Bertrand Russell Huber, MD, PhD

Assistant Professor, Neurology

Bertrand Huber
617.638.7730
150 S Huntington Avenue

Biography

Dr. Huber completed his undergraduate studies at the University of California Santa Cruz and earned a PhD degree in Biophysics at the University of California San Francisco. He earned his MD from the Harvard-MIT Health Science and Technology program. He completed residency training in Anatomic Pathology and fellowship training in Neuropathology at the University of Washington. Dr. Huber is an Assistant Professor of Neurology at Boston University and is the director of the PTSD Brain Bank at the Jamaica Plain Veterans Administration. He is a member of the New England Veterans Administration Medical Centers (VISN-1) Brain Banks and the Brain Banks for the Boston University Alzheimer’s Disease Center, Center for the Study of Traumatic Encephalopathy and Framingham Heart Study. Dr. Huber’s research interests center on the relationship between neurotrauma and neurodegenerative diseases, with a primary focus on the blood-brain barrier and neuroinflammation. Much of his current work centers on astrocytic injury in repetitive neurotrauma and the accumulation of tau pathology. He is an acting neuropathologist involved with the brain banks for the Boston University Alzheimer Disease Center, CTE Center, Framingham Heart Study, as well as the PTSD brain bank. Dr Huber is a member of the Society for Neuroscience, the College of American Pathologists, the American Society of Clinical Pathologists, and the International Society for Biological and Environmental Repositories.

Other Positions

  • VA Boston Healthcare System
  • Director of PTSD Brain Bank, Chronic Traumatic Encephalopathy (CTE) Center, Alzheimer's Disease Center, Boston University School of Medicine
  • Investigator, Framingham Heart Study

Education

  • Harvard Medical School, MD
  • University of California San Francisco, PhD
  • University of California, Santa Cruz, BA

Publications

  • Published on 6/5/2020

    Cherry JD, Kim SH, Stein TD, Pothast MJ, Nicks R, Meng G, Huber BR, Mez J, Alosco ML, Tripodis Y, Farrell K, Alvarez VE, McKee AC, Crary JF. Evolution of neuronal and glial tau isoforms in chronic traumatic encephalopathy. Brain Pathol. 2020 Jun 05. PMID: 32500646.

    Read at: PubMed
  • Published on 4/8/2020

    Greenberg A, Huber BR, Liu DX, Logue JP, Hischak AMW, Hart RJ, Abbott M, Isic N, Hisada YM, Mackman N, Bennett RS, Hensley LE, Connor JH, Crossland NA. Quantification of Viral and Host Biomarkers in the Liver of Rhesus Macaques: A Longitudinal Study of Zaire Ebolavirus Strain Kikwit (EBOV/Kik). Am J Pathol. 2020 Jul; 190(7):1449-1460. PMID: 32275904.

    Read at: PubMed
  • Published on 3/14/2020

    Logue MW, Miller MW, Wolf EJ, Huber BR, Morrison FG, Zhou Z, Zheng Y, Smith AK, Daskalakis NP, Ratanatharathorn A, Uddin M, Nievergelt CM, Ashley-Koch AE, Baker DG, Beckham JC, Garrett ME, Boks MP, Geuze E, Grant GA, Hauser MA, Kessler RC, Kimbrel NA, Maihofer AX, Marx CE, Qin XJ, Risbrough VB, Rutten BPF, Stein MB, Ursano RJ, Vermetten E, Vinkers CH, Ware EB, Stone A, Schichman SA, McGlinchey RE, Milberg WP, Hayes JP, Verfaellie M. An epigenome-wide association study of posttraumatic stress disorder in US veterans implicates several new DNA methylation loci. Clin Epigenetics. 2020 Mar 14; 12(1):46. PMID: 32171335.

    Read at: PubMed
  • Published on 11/26/2019

    Minaeva O, Hua N, Franz ES, Lupoli N, Mian AZ, Farris CW, Hildebrandt AM, Kiernan PT, Evers LE, Griffin AD, Liu X, Chancellor SE, Babcock KJ, Moncaster JA, Jara H, Alvarez VE, Huber BR, Guermazi A, Latour LL, McKee AC, Soto JA, Anderson SW, Goldstein LE. Nonhomogeneous Gadolinium Retention in the Cerebral Cortex after Intravenous Administration of Gadolinium-based Contrast Agent in Rats and Humans. Radiology. 2020 Feb; 294(2):377-385. PMID: 31769744.

    Read at: PubMed
  • Published on 11/23/2019

    Mez J, Daneshvar DH, Abdolmohammadi B, Chua AS, Alosco ML, Kiernan PT, Evers L, Marshall L, Martin BM, Palmisano JN, Nowinski CJ, Mahar I, Cherry JD, Alvarez VE, Dwyer B, Huber BR, Stein TD, Goldstein LE, Katz DI, Cantu RC, Au R, Kowall NW, Stern RA, McClean MD, Weuve J, Tripodis Y, McKee AC. Duration of American Football Play and Chronic Traumatic Encephalopathy. Ann Neurol. 2020 01; 87(1):116-131. PMID: 31589352.

    Read at: PubMed
  • Published on 8/5/2019

    Alosco ML, Stein TD, Tripodis Y, Chua AS, Kowall NW, Huber BR, Goldstein LE, Cantu RC, Katz DI, Palmisano JN, Martin B, Cherry JD, Mahar I, Killiany RJ, McClean MD, Au R, Alvarez V, Stern RA, Mez J, McKee AC. Association of White Matter Rarefaction, Arteriolosclerosis, and Tau With Dementia in Chronic Traumatic Encephalopathy. JAMA Neurol. 2019 Aug 05. PMID: 31380975.

    Read at: PubMed
  • Published on 6/10/2019

    Standring OJ, Friedberg J, Tripodis Y, Chua AS, Cherry JD, Alvarez VE, Huber BR, Xia W, Mez J, Alosco ML, Nicks R, Mahar I, Pothast MJ, Gardner HM, Meng G, Palmisano JN, Martin BM, Dwyer B, Kowall NW, Cantu RC, Goldstein LE, Katz DI, Stern RA, McKee AC, Stein TD. Contact sport participation and chronic traumatic encephalopathy are associated with altered severity and distribution of cerebral amyloid angiopathy. Acta Neuropathol. 2019 09; 138(3):401-413. PMID: 31183671.

    Read at: PubMed
  • Published on 12/1/2018

    Walt GS, Burris HM, Brady CB, Spencer KR, Alvarez VE, Huber BR, Guilderson L, Abdul Rauf N, Collins D, Singh T, Mathias R, Averill JG, Walker SE, Robey I, McKee AC, Kowall NW, Stein TD. Chronic Traumatic Encephalopathy Within an Amyotrophic Lateral Sclerosis Brain Bank Cohort. J Neuropathol Exp Neurol. 2018 12 01; 77(12):1091-1100. PMID: 30299493.

    Read at: PubMed
  • Published on 11/4/2018

    Cherry JD, Mez J, Crary JF, Tripodis Y, Alvarez VE, Mahar I, Huber BR, Alosco ML, Nicks R, Abdolmohammadi B, Kiernan PT, Evers L, Svirsky S, Babcock K, Gardner HM, Meng G, Nowinski CJ, Martin BM, Dwyer B, Kowall NW, Cantu RC, Goldstein LE, Katz DI, Stern RA, Farrer LA, McKee AC, Stein TD. Variation in TMEM106B in chronic traumatic encephalopathy. Acta Neuropathol Commun. 2018 11 04; 6(1):115. PMID: 30390709.

    Read at: PubMed
  • Published on 10/23/2018

    Morrison FG, Miller MW, Wolf EJ, Logue MW, Maniates H, Kwasnik D, Cherry JD, Svirsky S, Restaino A, Hildebrandt A, Aytan N, Stein TD, Alvarez VE, McKee AC, Huber BR. Reduced interleukin 1A gene expression in the dorsolateral prefrontal cortex of individuals with PTSD and depression. Neurosci Lett. 2019 01 23; 692:204-209. PMID: 30366016.

    Read at: PubMed

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