Bertrand Russell Huber, MD, PhD

Assistant Professor, Neurology

Bertrand Huber
617.638.7730
150 S Huntington Avenue

Biography

Dr. Huber completed his undergraduate studies at the University of California Santa Cruz and earned a PhD degree in Biophysics at the University of California San Francisco. He earned his MD from the Harvard-MIT Health Science and Technology program. He completed residency training in Anatomic Pathology and fellowship training in Neuropathology at the University of Washington. Dr. Huber is an Assistant Professor of Neurology at Boston University and is the director of the PTSD Brain Bank at the Jamaica Plain Veterans Administration. He is a member of the New England Veterans Administration Medical Centers (VISN-1) Brain Banks and the Brain Banks for the Boston University Alzheimer’s Disease Center, Center for the Study of Traumatic Encephalopathy and Framingham Heart Study. Dr. Huber’s research interests center on the relationship between neurotrauma and neurodegenerative diseases, with a primary focus on the blood-brain barrier and neuroinflammation. Much of his current work centers on astrocytic injury in repetitive neurotrauma and the accumulation of tau pathology. He is an acting neuropathologist involved with the brain banks for the Boston University Alzheimer Disease Center, CTE Center, Framingham Heart Study, as well as the PTSD brain bank. Dr Huber is a member of the Society for Neuroscience, the College of American Pathologists, the American Society of Clinical Pathologists, and the International Society for Biological and Environmental Repositories.

Other Positions

  • Investigator, Framingham Heart Study
  • Director of PTSD Brain Bank, Chronic Traumatic Encephalopathy (CTE) Center, Alzheimer's Disease Center, Boston University Chobanian & Avedisian School of Medicine
  • VA Boston Healthcare System

Education

  • Harvard Medical School, MD
  • University of California San Francisco, PhD
  • University of California, Santa Cruz, BA

Publications

  • Published on 11/23/2022

    Yang J, Chang S, Chen IA, Kura S, Rosen GA, Saltiel NA, Huber BR, Varadarajan D, Balbastre Y, Magnain C, Chen SC, Fischl B, McKee AC, Boas DA, Wang H. Volumetric Characterization of Microvasculature in Ex Vivo Human Brain Samples By Serial Sectioning Optical Coherence Tomography. IEEE Trans Biomed Eng. 2022 Dec; 69(12):3645-3656. PMID: 35560084.

    Read at: PubMed
  • Published on 9/19/2022

    Butler MLMD, Dixon E, Stein TD, Alvarez VE, Huber B, Buckland ME, McKee AC, Cherry JD. Tau Pathology in Chronic Traumatic Encephalopathy is Primarily Neuronal. J Neuropathol Exp Neurol. 2022 Sep 19; 81(10):773-780. PMID: 35903039.

    Read at: PubMed
  • Published on 8/1/2022

    Atherton K, Han X, Chung J, Cherry JD, Baucom Z, Saltiel N, Nair E, Abdolmohammadi B, Uretsky M, Khan MM, Shea C, Durape S, Martin BM, Palmisano JN, Farrell K, Nowinski CJ, Alvarez VE, Dwyer B, Daneshvar DH, Katz DI, Goldstein LE, Cantu RC, Kowall NW, Alosco ML, Huber BR, Tripodis Y, Crary JF, Farrer L, Stern RA, Stein TD, McKee AC, Mez J. Association of APOE Genotypes and Chronic Traumatic Encephalopathy. JAMA Neurol. 2022 Aug 01; 79(8):787-796. PMID: 35759276.

    Read at: PubMed
  • Published on 6/4/2022

    Colvin LE, Foster ZW, Stein TD, Thakore-James M, Salajegheh MK, Carr K, Spencer KR, Abdul Rauf N, Adams L, Averill JG, Walker SE, Robey I, Alvarez VE, Huber BR, McKee AC, Kowall NW, Brady CB. Utility of the ALSFRS-R for predicting ALS and comorbid disease neuropathology: The Veterans Affairs Biorepository Brain Bank. Muscle Nerve. 2022 Aug; 66(2):167-174. PMID: 35585776.

    Read at: PubMed
  • Published on 5/26/2022

    Rosenbloom R, Gavrish I, Tseng AE, Seidel K, Yabaji SM, Gertje HP, Huber BR, Kramnik I, Crossland NA. Progression and Dissemination of Pulmonary Mycobacterium Avium Infection in a Susceptible Immunocompetent Mouse Model. Int J Mol Sci. 2022 May 26; 23(11). PMID: 35682679.

    Read at: PubMed
  • Published on 5/19/2022

    Alvia M, Aytan N, Spencer KR, Foster ZW, Rauf NA, Guilderson L, Robey I, Averill JG, Walker SE, Alvarez VE, Huber BR, Mathais R, Cormier KA, Nicks R, Pothast M, Labadorf A, Agus F, Alosco ML, Mez J, Kowall NW, McKee AC, Brady CB, Stein TD. MicroRNA Alterations in Chronic Traumatic Encephalopathy and Amyotrophic Lateral Sclerosis. Front Neurosci. 2022; 16:855096. PMID: 35663558.

    Read at: PubMed
  • Published on 4/13/2022

    Babcock KJ, Abdolmohammadi B, Kiernan PT, Mahar I, Cherry JD, Alvarez VE, Goldstein LE, Stein TD, McKee AC, Huber BR. Interface astrogliosis in contact sport head impacts and military blast exposure. Acta Neuropathol Commun. 2022 Apr 13; 10(1):52. PMID: 35418116.

    Read at: PubMed
  • Published on 4/4/2022

    Kenney DJ, O'Connell AK, Turcinovic J, Montanaro P, Hekman RM, Tamura T, Berneshawi AR, Cafiero TR, Al Abdullatif S, Blum B, Goldstein SI, Heller BL, Gertje HP, Bullitt E, Trachtenberg AJ, Chavez E, Nono ET, Morrison C, Tseng AE, Sheikh A, Kurnick S, Grosz K, Bosmann M, Ericsson M, Huber BR, Saeed M, Balazs AB, Francis KP, Klose A, Paragas N, Campbell JD, Connor JH, Emili A, Crossland NA, Ploss A, Douam F. Humanized mice reveal a macrophage-enriched gene signature defining human lung tissue protection during SARS-CoV-2 infection. Cell Rep. 2022 Apr 19; 39(3):110714. PMID: 35421379.

    Read at: PubMed
  • Published on 3/5/2022

    Carossino M, Kenney D, O'Connell AK, Montanaro P, Tseng AE, Gertje HP, Grosz KA, Ericsson M, Huber BR, Kurnick SA, Subramaniam S, Kirkland TA, Walker JR, Francis KP, Klose AD, Paragas N, Bosmann M, Saeed M, Balasuriya UBR, Douam F, Crossland NA. Fatal Neurodissemination and SARS-CoV-2 Tropism in K18-hACE2 Mice Is Only Partially Dependent on hACE2 Expression. Viruses. 2022 03 05; 14(3). PMID: 35336942.

    Read at: PubMed
  • Published on 2/26/2022

    Pierce ME, Hayes J, Huber BR, Jeromin A, Fortier CB, Fonda JR, Lasseter H, Chaby L, McGlinchey R, Milberg W. Plasma biomarkers associated with deployment trauma and its consequences in post-9/11 era veterans: initial findings from the TRACTS longitudinal cohort. Transl Psychiatry. 2022 02 26; 12(1):80. PMID: 35217643.

    Read at: PubMed

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