Barbara E. Slack, PhD

Associate Professor, Pathology & Laboratory Medicine

Barbara Slack
617.358.2240
72 E. Concord St Instructional (L)

Biography

Barbara Slack, PhD, is an Associate Professor of Pathology & Laboratory Medicine at the Chobanian and Avedisian School of Medicine.She has been a member of the faculty since 1995. Previously, Dr. Slack was a research and postdoctoral fellow at both MIT and Harvard University. Her laboratory studies signal transduction pathways coupled to G protein-coupled receptors.

Other Positions

  • Graduate Faculty (Primary Mentor of Grad Students), Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences

Education

  • Queen's University, PhD
  • Queen's University, MSc
  • Queen's University, BS

Classes Taught

  • GMSPA600

Publications

  • Published on 1/1/2023

    Blusztajn JK, Slack BE. Accelerated Breakdown of Phosphatidylcholine and Phosphatidylethanolamine Is a Predominant Brain Metabolic Defect in Alzheimer's Disease. J Alzheimers Dis. 2023; 93(4):1285-1289. PMID: 37182883.

    Read at: PubMed
  • Published on 7/28/2017

    Blusztajn JK, Slack BE, Mellott TJ. Neuroprotective Actions of Dietary Choline. Nutrients. 2017 Jul 28; 9(8). PMID: 28788094.

    Read at: PubMed
  • Published on 3/23/2017

    Mellott TJ, Huleatt OM, Shade BN, Pender SM, Liu YB, Slack BE, Blusztajn JK. Correction: Perinatal Choline Supplementation Reduces Amyloidosis and Increases Choline Acetyltransferase Expression in the Hippocampus of the APPswePS1dE9 Alzheimer's Disease Model Mice. PLoS One. 2017; 12(3):e0174875. PMID: 28334015.

    Read at: PubMed
  • Published on 1/19/2017

    Mellott TJ, Huleatt OM, Shade BN, Pender SM, Liu YB, Slack BE, Blusztajn JK. Perinatal Choline Supplementation Reduces Amyloidosis and Increases Choline Acetyltransferase Expression in the Hippocampus of the APPswePS1dE9 Alzheimer's Disease Model Mice. PLoS One. 2017; 12(1):e0170450. PMID: 28103298.

    Read at: PubMed
  • Published on 11/11/2013

    Burke RM, Norman TA, Haydar TF, Slack BE, Leeman SE, Blusztajn JK, Mellott TJ. BMP9 ameliorates amyloidosis and the cholinergic defect in a mouse model of Alzheimer's disease. Proc Natl Acad Sci U S A. 2013 Nov 26; 110(48):19567-72. PMID: 24218590.

    Read at: PubMed
  • Published on 6/29/2012

    Akle V, Guelin E, Yu L, Brassard-Giordano H, Slack BE, Zhdanova IV. F-spondin/spon1b expression patterns in developing and adult zebrafish. PLoS One. 2012; 7(6):e37593. PMID: 22768035.

    Read at: PubMed
  • Published on 5/17/2011

    Cissé M, Duplan E, Guillot-Sestier MV, Rumigny J, Bauer C, Pagès G, Orzechowski HD, Slack BE, Checler F, Vincent B. The extracellular regulated kinase-1 (ERK1) controls regulated alpha-secretase-mediated processing, promoter transactivation, and mRNA levels of the cellular prion protein. J Biol Chem. 2011 Aug 19; 286(33):29192-206. PMID: 21586567.

    Read at: PubMed
  • Published on 5/17/2011

    Carey RM, Blusztajn JK, Slack BE. Surface expression and limited proteolysis of ADAM10 are increased by a dominant negative inhibitor of dynamin. BMC Cell Biol. 2011; 12:20. PMID: 21586144.

    Read at: PubMed
  • Published on 7/27/2009

    Kishi S, Slack BE, Uchiyama J, Zhdanova IV. Zebrafish as a genetic model in biological and behavioral gerontology: where development meets aging in vertebrates--a mini-review. Gerontology. 2009; 55(4):430-41. PMID: 19654474.

    Read at: PubMed
  • Published on 8/1/2008

    Slack BE, Blusztajn JK. Differential regulation of mTOR-dependent S6 phosphorylation by muscarinic acetylcholine receptor subtypes. J Cell Biochem. 2008 Aug 1; 104(5):1818-31. PMID: 18348264.

    Read at: PubMed

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