Andrea I. Havasi, MD

Assistant Professor, Medicine

Andrea Havasi
617.638.7330
650 Albany St Evans Biomed Research Ctr

Biography

Andrea Havasi, M.D. is an Assistant Professor of Medicine at Boston University. She is board certified in Internal Medicine and Nephrology. As a recipient of the National Kidney Foundation Research Fellow Award, she undertook research training at BMC investigating the cytoprotective mechanisms of heat shock proteins in ischemic renal cell injury and apoptosis. She joined the Renal Section Faculty in 2008, and continues basic and translational research in the area of renal cell injury and proteinuric kidney diseases using cell culture and animal models. She is the recipient of the American Heart Association Scientist Development Grant and NIH K08 award. She also has a special clinical and research interest in onco-nephrology and amyloidosis, and is a faculty in BU’s Amyloidosis Center. Dr. Havasi is a Co-Director of BU’s Mitochondria Affinity Research Collaborative, and Director of Nephrology Fellowship Program’s Onco-nephrology / Amyloidosis Pathway. Her clinical roles include attending time on the consult and dialysis/transplant services and weekly outpatient clinics (amyloidosis, chronic kidney disease, hemodialysis and peritoneal dialysis clinics).
Current research interest:
1. Amyloid renal disease
Mechanism of amyloid fibril formation and deposition in the kidney.
2. Proteinuria and renal fibrosis
Mechanisms of proteinuria induced tubular damage, interstitial fibrosis and inflammation in progressive kidney diseases. Proteinuria is associated with progressive chronic kidney disease. It is well known that exposure of proximal tubular epithelial cells to large amounts of albumin leads to the development of tubular atrophy and fibrosis. However, the possible pathogenic role of albumin in this process has not been fully elucidated. Development of new therapeutic tools to prevent or slow the progression of proteinuric chronic kidney disease requires clear understanding of the effect of proteinuria on tubular cell function.

Other Positions

  • Active Staff Hospital Privileges, Medicine, Boston Medical Center

Education

  • Semmelweis University, MD

Publications

  • Published on 1/1/2019

    Wang Z, Salih E, Igwebuike C, Mulhern R, Bonegio RG, Havasi A, Borkan SC. Nucleophosmin Phosphorylation as a Diagnostic and Therapeutic Target for Ischemic AKI. J Am Soc Nephrol. 2019 Jan; 30(1):50-62. PMID: 30573638.

    Read at: PubMed
  • Published on 12/21/2018

    Angel-Korman A, Stern L, Sarosiek S, Sloan JM, Doros G, Sanchorawala V, Havasi A. Long-term outcome of kidney transplantation in AL amyloidosis. Kidney Int. 2019 Feb; 95(2):405-411. PMID: 30580886.

    Read at: PubMed
  • Published on 2/24/2018

    Havasi A, Doros G, Sanchorawala V. Predictive value of the new renal response criteria in AL amyloidosis treated with high dose melphalan and stem cell transplantation. Am J Hematol. 2018 05; 93(5):E129-E132. PMID: 29430701.

    Read at: PubMed
  • Published on 9/12/2017

    Wang Z, Gall JM, Bonegio R, Havasi A, Illanes K, Schwartz JH, Borkan SC. Correction for Wang et al., "Nucleophosmin, a Critical Bax Cofactor in Ischemia-Induced Cell Death". Mol Cell Biol. 2017 10 01; 37(19). PMID: 28899998.

    Read at: PubMed
  • Published on 9/1/2017

    Batalini F, Econimo L, Quillen K, Sloan JM, Sarosiek S, Brauneis D, Havasi A, Stern L, Dember LM, Sanchorawala V. High-Dose Melphalan and Stem Cell Transplantation in Patients on Dialysis Due to Immunoglobulin Light-Chain Amyloidosis and Monoclonal Immunoglobulin Deposition Disease. Biol Blood Marrow Transplant. 2018 01; 24(1):127-132. PMID: 28865972.

    Read at: PubMed
  • Published on 7/29/2017

    Prokaeva T, Akar H, Spencer B, Havasi A, Cui H, O'Hara CJ, Gursky O, Leszyk J, Steffen M, Browning S, Rosenberg A, Connors LH. Hereditary Renal Amyloidosis Associated With a Novel Apolipoprotein A-II Variant. Kidney Int Rep. 2017 Nov; 2(6):1223-1232. PMID: 29270531.

    Read at: PubMed
  • Published on 9/21/2016

    Havasi A, Lu W, Cohen HT, Beck L, Wang Z, Igwebuike C, Borkan SC. Blocking peptides and molecular mimicry as treatment for kidney disease. Am J Physiol Renal Physiol. 2017 Jun 01; 312(6):F1016-F1025. PMID: 27654896.

    Read at: PubMed
  • Published on 9/15/2016

    Menn-Josephy H, Lee CS, Nolin A, Christov M, Rybin DV, Weinberg JM, Henderson J, Bonegio R, Havasi A. Renal Interstitial Fibrosis: An Imperfect Predictor of Kidney Disease Progression in Some Patient Cohorts. Am J Nephrol. 2016; 44(4):289-299. PMID: 27626625.

    Read at: PubMed
  • Published on 8/31/2016

    Nolin AC, Mulhern RM, Panchenko MV, Pisarek-Horowitz A, Wang Z, Shirihai O, Borkan SC, Havasi A. Proteinuria causes dysfunctional autophagy in the proximal tubule. Am J Physiol Renal Physiol. 2016 Dec 01; 311(6):F1271-F1279. PMID: 27582098.

    Read at: PubMed
  • Published on 7/14/2016

    Havasi A, Stern L, Lo S, Sun F, Sanchorawala V. Validation of new renal staging system in AL amyloidosis treated with high dose melphalan and stem cell transplantation. Am J Hematol. 2016 10; 91(10):E458-60. PMID: 27356490.

    Read at: PubMed

View 20 more publications: View full profile at BUMC

View all profiles