Ajit K. Bharti, PhD

Research Assistant Professor, Medicine

(617) 414-1694
650 Albany St Evans Biomed Research Ctr

Biography

Expertise in regulation of proteins by post-translation modifications, determining the molecular mechanisms of anti cancer drugs.

Other Positions

  • Boston Medical Center

Education

  • Ranchi University, PhD
  • Ranchi University, MS
  • Ranchi University, BS

Publications

  • Published on 7/4/2017

    Ando K, Shah AK, Sachdev V, Kleinstiver BP, Taylor-Parker J, Welch MM, Hu Y, Salgia R, White FM, Parvin JD, Ozonoff A, Rameh LE, Joung JK, Bharti AK. Camptothecin resistance is determined by the regulation of topoisomerase I degradation mediated by ubiquitin proteasome pathway. Oncotarget. 2017 Jul 04; 8(27):43733-43751. PMID: 28415827.

    Read at: PubMed
  • Published on 8/12/2015

    Raina D, Agarwal P, Lee J, Bharti A, McKnight CJ, Sharma P, Kharbanda S, Kufe D. Characterization of the MUC1-C Cytoplasmic Domain as a Cancer Target. PLoS One. 2015; 10(8):e0135156. PMID: 26267657.

    Read at: PubMed
  • Published on 12/10/2013

    Rolle CE, Kanteti R, Surati M, Nandi S, Dhanasingh I, Yala S, Tretiakova M, Arif Q, Hembrough T, Brand TM, Wheeler DL, Husain AN, Vokes EE, Bharti A, Salgia R. Combined MET inhibition and topoisomerase I inhibition block cell growth of small cell lung cancer. Mol Cancer Ther. 2014 Mar; 13(3):576-84. PMID: 24327519.

    Read at: PubMed
  • Published on 1/5/2012

    Icli B, Bharti A, Pentassuglia L, Peng X, Sawyer DB. ErbB4 localization to cardiac myocyte nuclei, and its role in myocyte DNA damage response. Biochem Biophys Res Commun. 2012 Feb 3; 418(1):116-21. PMID: 22244893.

    Read at: PubMed
  • Published on 7/29/2011

    Tamayo AG, Slater L, Taylor-Parker J, Bharti A, Harrison R, Hung DT, Murphy JR. GRP78(BiP) facilitates the cytosolic delivery of anthrax lethal factor (LF) in vivo and functions as an unfoldase in vitro. Mol Microbiol. 2011 Sep; 81(5):1390-401. PMID: 21797942.

    Read at: PubMed
  • Published on 11/9/2010

    Murshid A, Chou SD, Prince T, Zhang Y, Bharti A, Calderwood SK. Protein kinase A binds and activates heat shock factor 1. PLoS One. 2010; 5(11):e13830. PMID: 21085490.

    Read at: PubMed
  • Published on 4/1/2010

    Shah A, Singh H, Sachdev V, Lee J, Yotsukura S, Salgia R, Bharti A. DIFFERENTIAL SERUM LEVEL OF SPECIFIC HAPTOGLOBIN ISOFORMS IN SMALL CELL LUNG CANCER. Curr Proteomics. 2010 Apr 01; 7(1):49-65. PMID: 20526421.

    Read at: PubMed
  • Published on 9/21/2008

    Chitalia VC, Foy RL, Bachschmid MM, Zeng L, Panchenko MV, Zhou MI, Bharti A, Seldin DC, Lecker SH, Dominguez I, Cohen HT. Jade-1 inhibits Wnt signalling by ubiquitylating beta-catenin and mediates Wnt pathway inhibition by pVHL. Nat Cell Biol. 2008 Oct; 10(10):1208-16. PMID: 18806787.

    Read at: PubMed
  • Published on 3/20/2008

    Tamayo AG, Bharti A, Trujillo C, Harrison R, Murphy JR. COPI coatomer complex proteins facilitate the translocation of anthrax lethal factor across vesicular membranes in vitro. Proc Natl Acad Sci U S A. 2008 Apr 1; 105(13):5254-9. PMID: 18356299.

    Read at: PubMed
  • Published on 5/1/2007

    Bharti A, Ma PC, Salgia R. Biomarker discovery in lung cancer--promises and challenges of clinical proteomics. Mass Spectrom Rev. 2007 May-Jun; 26(3):451-66. PMID: 17407130.

    Read at: PubMed

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