Rigor and Reproducibility of Scientific Research

Students are expected to acquire skills in experimental design and analysis, replication of experimental findings, and critical analysis of the validity of experimental approaches to enhance the rigor of their work and its potential reproducibility by other investigators. Publications addressing deficiencies in these aspects of scientific research are posted below:

Collins and Tabak 2014 Nature 505 (7485) 612-613

Prinz et al Nature Review _ Drug Discovery

Story Landis 2012 Nature 490(7419) 187-191

Students will be expected to consider these issues as part of the critique of publications in the course Current Topics in the Pharmacological Sciences.