November 16, 2018 BU Pharmacology-Biogen Symposium: Innovations in Neuroscience Discovery

Innovations in Neuroscience Drug Discovery

Friday, November 16th 2018, 8:00 a.m. – 6:30 p.m.

BU Pharmacology & Experimental Therapeutics – Biogen Symposium

Biogen, 300 Binney Street, Cambridge, MA  02142

Free and open to the public. 


Registration has now closed.  There is no onsite registration.

BU-Biogen Symposium booklet_20181107_230pm


Registration and Breakfast

David H. Farb, Ph.D., Boston University: Academia-Industry Alliances: Catalyzing Discovery Science

Anabella Villalobos, Ph.D., Biogen: Biogen Opening Remarks

Session 1: Harnessing Cutting-Edge Technology to Enable Drug Discovery

Georgios Skiniotis, Ph.D., Stanford University: CryoEM Insights into GPCR Activation and Signaling

Anthony W. P. Fitzpatrick, Ph.D., Columbia University: Untangling Neurodegenerative Diseases Using Patient-Based Structural Biology

Shelley J. Russek, Ph.D., Boston University: JAK/STATs and the Brain: a Pharmacological Window on the BDNF Transcriptome of Neurological Disease

Hongkui Zeng, Ph.D., Allen Institute for Brain Science: Cell Type Classification and Circuit Mapping in the Brain: Mapping a Path to Discovery

Xue Han, Ph.D., Boston University: Optical Analysis of Biological Neural Networks Across Scales

Session 2: Neuroinflammation at the Nexus of CNS Diseases

Anirvan Ghosh, Ph.D., Biogen: Introductory Remarks

Staci Bilbo, Ph.D., MGH/Harvard Medical School: Neuroimmune Interactions in Development: Implications for Health Throughout the Lifespan

Dorothy P. Schafer, Ph.D., UMASS Medical Center: Microglial Phagocytic Mechanisms Governing Brain Plasticity in Health and Disease

Tsuneya Ikezu, M.D., Ph.D., Boston University: Proteomic and Neuropathological Characterization of Extracellular Vesicles in Alzheimer’s Disease 

Benjamin Wolozin, M.D., Ph.D., Boston University: Membrane-Less Organelles and RNA Binding Proteins as Targets  for Therapy of Neurodegenerative Diseases 

Session 3: Pharmacology, Models and Biomarkers: Bench to Bedside

Leonard Petrucelli, Ph.D., Mayo Clinic-Jacksonville: Therapeutic Insights into Repeat Expansion Disorders

Wendy Qiu, M.D., Ph.D., Boston University: Alzheimer’s Disease: The Brain Disease or the Peripheral System-Brain Axis Disease?

Thomas Kornecook, Ph.D., Biogen: Animal Models in Neuroscience Drug Discovery: The Good, the Bad, and the Ugly

Himanshu Naik, Ph.D., Biogen: Application of Pharmacokinetic and Pharmacodynamic Modeling in Drug Development

Closing Remarks