{"id":1440,"date":"2009-12-04T09:49:57","date_gmt":"2009-12-04T14:49:57","guid":{"rendered":"https:\/\/www.bumc.bu.edu\/busm-pathology\/2009\/12\/04\/december-2009\/"},"modified":"2009-12-04T09:49:57","modified_gmt":"2009-12-04T14:49:57","slug":"december-2009","status":"publish","type":"post","link":"https:\/\/www.bumc.bu.edu\/busm-pathology\/2009\/12\/04\/december-2009\/","title":{"rendered":"December 2009"},"content":{"rendered":"<h2>Pathology &amp; Laboratory Medicine News Items<\/h2>\n<h3>Announcements<\/h3>\n<ul>\n<li><strong>Bryan Belikoff, MD\/PhD candidate<\/strong> has recently been placed on the Hematology Training Grant.<\/li>\n<li><strong>Grants:<\/strong>\n<ul>\n<li><strong>Marten Steffen\u2019s, PhD <\/strong>recently awarded Grand Opportunity Grant (1RC2GM092602-01; multi-PI: Steffen, Kasif, Roberts) has been highlighted in an <a href=\"http:\/\/www.nih.gov\/news\/health\/nov2009\/nigms-23.htm\">NIH news release<\/a>. The goal of the grant, entitled \u201cSciBay: A New Methodology for Scientific Collaboration and Gene Function Determination,\u201d is to catalyze experimental validation of gene function for genes with no known function in bacterial genomes. This grant will implement the experimental validation model proposed by co-PI Rich Roberts, the recipient of the 1993 Nobel Prize in Physiology or Medicine for his discovery of introns.\u00a0\u00a0 We will form a consortium of experimental and computational biologists that would collaborate directly to test experimentally the predicted functions of high-priority genes of currently unknown function or specificity. This high profile initiative is our attempt to ameliorate a profound problem exacerbated by next generation sequencing methods.\u00a0\u00a0 If one were to sequence a newly discovered microbe today, the percentage of genes of unknown function would be very similar to that obtained a decade ago.\u00a0\u00a0 We anticipate that, in the near future, as the new methods become more widely used, and generate giga- and tera-bases of new sequence data, this problem will become quantitatively worse.\u00a0\u00a0 It is therefore imperative that we develop both new methods and opportunities for determining gene function.<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<h3>Publications-ACCEPTED<\/h3>\n<ul>\n<li><strong>Marier Hernandez-Perez MD<\/strong>, one of our current residents, has a paper accepted for publication at The American Journal of Surgical Pathology Title:\u00a0 \u201cDistinctive Association of p16INK4a Over-expression with Penile Intraepithelial Neoplasia (PeIN)Depicting Warty and\/or Basaloid Features: A study of 141 Cases Evaluating a New Nomenclature.\u201d \u00a0 Authors: Alcides Chaux, M.D.; Rolf Pfannl, M.D.; Bel\u00e9n Lloveras; Mar\u00eda Alejo; Omar Clavero; Cecilia Lezcano; Nubia Mu\u00f1oz; de Sanjos\u00e9 Silvia, M.D., Ph.D.; Xavier Bosch;<strong> Marier Hern\u00e1ndez-P\u00e9rez, M.D.<\/strong>; Elsa F Velazquez, M.D.; Antonio L Cubilla, M.D.<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Pathology &amp; Laboratory Medicine News Items Announcements Bryan Belikoff, MD\/PhD candidate has recently been placed on the Hematology Training Grant. Grants: Marten Steffen\u2019s, PhD recently awarded Grand Opportunity Grant (1RC2GM092602-01; multi-PI: Steffen, Kasif, Roberts) has been highlighted in an NIH news release. The goal of the grant, entitled \u201cSciBay: A New Methodology for Scientific Collaboration [&hellip;]<\/p>\n","protected":false},"author":1131,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[1],"tags":[],"_links":{"self":[{"href":"https:\/\/www.bumc.bu.edu\/busm-pathology\/wp-json\/wp\/v2\/posts\/1440"}],"collection":[{"href":"https:\/\/www.bumc.bu.edu\/busm-pathology\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.bumc.bu.edu\/busm-pathology\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/busm-pathology\/wp-json\/wp\/v2\/users\/1131"}],"replies":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/busm-pathology\/wp-json\/wp\/v2\/comments?post=1440"}],"version-history":[{"count":0,"href":"https:\/\/www.bumc.bu.edu\/busm-pathology\/wp-json\/wp\/v2\/posts\/1440\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.bumc.bu.edu\/busm-pathology\/wp-json\/wp\/v2\/media?parent=1440"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/busm-pathology\/wp-json\/wp\/v2\/categories?post=1440"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/busm-pathology\/wp-json\/wp\/v2\/tags?post=1440"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}