{"id":14235,"date":"2016-12-05T09:07:23","date_gmt":"2016-12-05T14:07:23","guid":{"rendered":"https:\/\/www.bumc.bu.edu\/busm-pathology\/?p=14235"},"modified":"2016-12-05T09:07:23","modified_gmt":"2016-12-05T14:07:23","slug":"pathology-laboratory-medicine-news-items-november-2016","status":"publish","type":"post","link":"https:\/\/www.bumc.bu.edu\/busm-pathology\/2016\/12\/05\/pathology-laboratory-medicine-news-items-november-2016\/","title":{"rendered":"Pathology &#038; Laboratory Medicine News Items \u2013 November 2016"},"content":{"rendered":"<p><strong><span style=\"text-decoration: underline;\">Pathology &amp; Laboratory Medicine News Items \u2013 November 2016<\/span><\/strong><\/p>\n<ul>\n<li><span style=\"text-decoration: underline;\"><strong>Announcements:<\/strong><\/span>\n<ul>\n<li><strong><span style=\"text-decoration: underline;\">Dr. Shinichiro Kurosawa <\/span><\/strong><span style=\"text-decoration: underline;\"><\/span>has been reappointed to the Boston University Laboratory Safety Committee. The term of his appointment is through December 31, 2018<\/li>\n<li><span style=\"text-decoration: underline;\">Dr. Chris Andry<\/span> has had his appointment extend as Chair of the Boston University Laboratory Safety Committee. The term of his extension is through December 31, 2018<\/li>\n<li><strong><span style=\"text-decoration: underline;\">Jacquelyn Sikora Hanson, PhD <\/span><\/strong><span style=\"text-decoration: underline;\"><\/span>(Lawreen Connors Lab) successfully defended her Thesis, \u201cTransthyretin gene regulation in wild-type transthyretin amyloidosis\u201d on November 21<sup>st<\/sup>, 2016, BRAVO!!<\/li>\n<li><strong>\u00a0 <\/strong><a href=\"\/busm-pathology\/files\/2016\/12\/Defense3.jpg\"><strong><img loading=\"lazy\" width=\"216\" height=\"216\" class=\"  wp-image-14236 alignleft\" alt=\"defense3\" src=\"\/busm-pathology\/files\/2016\/12\/Defense3-150x150.jpg\" srcset=\"https:\/\/www.bumc.bu.edu\/busm-pathology\/files\/2016\/12\/Defense3-150x150.jpg 150w, https:\/\/www.bumc.bu.edu\/busm-pathology\/files\/2016\/12\/Defense3-100x100.jpg 100w\" sizes=\"(max-width: 216px) 100vw, 216px\" \/><\/strong><\/a><strong>\u00a0\u00a0\u00a0<\/strong><\/li>\n<li><strong>\u00a0\u00a0\u00a0\u00a0\u00a0 <\/strong><\/li>\n<li><strong><\/strong><\/li>\n<li><strong>\u00a0<\/strong><\/li>\n<li><strong>\u00a0\u00a0 <\/strong><\/li>\n<li><strong>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <\/strong><\/li>\n<li><strong><\/strong><\/li>\n<li><strong><\/strong><\/li>\n<li><strong>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <\/strong><\/li>\n<li>Dr. Sikora Hanson\u2019s Defense Dissertation<\/li>\n<li><a href=\"\/busm-pathology\/files\/2016\/12\/Committee.Trinkaus.Randall.Connors.Hanson.Sherr_.jpg\"><\/a><\/li>\n<li>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Jacquelyn\u2019s Thesis Committee:\u00a0Dr. Vickery Trinkaus-Randall,<\/li>\n<li>Dr. Lawreen Connors (PI), new Dr. Sikora Hanson\u00a0and Dr. David Sherr\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<strong> <\/strong><\/li>\n<li><strong>\u00a0\u00a0\u00a0\u00a0\u00a0<\/strong><a href=\"\/busm-pathology\/files\/2016\/12\/Committee.Trinkaus.Randall.Connors.Hanson.Sherr_.jpg\"><strong><img loading=\"lazy\" width=\"210\" height=\"210\" class=\"alignleft  wp-image-14237\" alt=\"committee-trinkaus-randall-connors-hanson-sherr\" src=\"\/busm-pathology\/files\/2016\/12\/Committee.Trinkaus.Randall.Connors.Hanson.Sherr_-150x150.jpg\" srcset=\"https:\/\/www.bumc.bu.edu\/busm-pathology\/files\/2016\/12\/Committee.Trinkaus.Randall.Connors.Hanson.Sherr_-150x150.jpg 150w, https:\/\/www.bumc.bu.edu\/busm-pathology\/files\/2016\/12\/Committee.Trinkaus.Randall.Connors.Hanson.Sherr_-100x100.jpg 100w\" sizes=\"(max-width: 210px) 100vw, 210px\" \/><\/strong><\/a><strong>\u00a0<\/strong><strong>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/strong><\/li>\n<\/ul>\n<p><strong>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/strong>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<strong> <\/strong><\/li>\n<li><\/li>\n<li><a href=\"\/busm-pathology\/files\/2016\/12\/Dr.-Hanson-and-Family.-Stephen.Brother.Ginger.MomandRay.Dad_.jpg\"><img loading=\"lazy\" width=\"206\" height=\"206\" class=\"  wp-image-14239 aligncenter\" alt=\"dr-hanson-and-family-stephen-brother-ginger-momandray-dad\" src=\"\/busm-pathology\/files\/2016\/12\/Dr.-Hanson-and-Family.-Stephen.Brother.Ginger.MomandRay.Dad_-150x150.jpg\" srcset=\"https:\/\/www.bumc.bu.edu\/busm-pathology\/files\/2016\/12\/Dr.-Hanson-and-Family.-Stephen.Brother.Ginger.MomandRay.Dad_-150x150.jpg 150w, https:\/\/www.bumc.bu.edu\/busm-pathology\/files\/2016\/12\/Dr.-Hanson-and-Family.-Stephen.Brother.Ginger.MomandRay.Dad_-100x100.jpg 100w\" sizes=\"(max-width: 206px) 100vw, 206px\" \/><\/a><\/li>\n<li><strong>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 \u00a0<\/strong>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 \u00a0\u00a0Dr. Jacquelyn Sikora Hanson and her proud family<\/li>\n<li>&nbsp;<\/li>\n<li><strong><\/strong><strong><span style=\"text-decoration: underline;\">Shark Tank Winners<\/span><\/strong>. The Cancer Center held a retreat on November 29<sup>th<\/sup> that featured a \u201cShark Tank\u201d styled competition for research funds. Prior to the retreat faculty were asked to submit brief proposals and the top 4 proposals were selected for presentation. During lunch each group had 5 minutes to make their pitch to the Sharks on the expert panel. <strong><span style=\"text-decoration: underline;\">David Sherr<\/span><\/strong> and <strong><span style=\"text-decoration: underline;\">Dan Remick<\/span><\/strong> submitted a proposal <strong>AHR Inhibitors as Novel Immune Checkpoint Inhibitors. <\/strong>\u00a0Their idea was selected as the winner. Portions of the funds will be used for processing specimens in the Ex+.<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<ul><\/ul>\n<p>&nbsp;<\/p>\n<p><strong><span style=\"text-decoration: underline;\">Publications ACCEPTED:<\/span><\/strong><b><strong><span style=\"text-decoration: underline;\"><\/span><\/strong><\/b><\/p>\n<ul>\n<li><b><strong><span style=\"text-decoration: underline;\">Hot Off the Presses: <\/span><\/strong><\/b><span style=\"text-decoration: underline;\"><\/span>The manuscript below has been accepted for publication in <em>Neuropsychiatric Genetics<\/em>. \u00a0While the first four authors worked in <span style=\"text-decoration: underline;\"><strong>Dr. Ivana Delalle\u2019s<\/strong><\/span> laboratory, it is really a multi-institutional effort that Dr. Delalle was fortunate to lead. \u00a0&#8220;Exosomal miR-149 and miR-29c as Candidates for Bipolar Disorder Biomarkers&#8221; by\u00a0Jason L. Choi<sup>1<\/sup>, <span style=\"text-decoration: underline;\"><strong>Patricia F. Kao<\/strong><\/span><strong><sup>1<\/sup><\/strong><strong>, Elena Itriago<\/strong><sup>1<\/sup>, Yougen Zhan<sup>1<\/sup>, James A. Kozubek<sup>2<\/sup>, Andrew G. Hoss<sup>3<\/sup>, Meredith G. Banigan<sup>4<\/sup>, Charles R. Vanderburg<sup>4<\/sup>, Amir H. Rezvani<sup>5<\/sup>, Jeanne C. Latourelle<sup>3<\/sup>, Howard Cabral<sup>6<\/sup>, and <span style=\"text-decoration: underline;\"><strong>Ivana Delalle<\/strong><\/span><sup><span style=\"text-decoration: underline;\"><strong>1<\/strong><\/span>#<\/sup><span style=\"text-decoration: underline;\">; <\/span><sup>1<\/sup>Department of Pathology and Laboratory Medicine, Boston University School of Medicine, Boston, MA 02118<span style=\"text-decoration: underline;\">; <\/span><sup>2<\/sup>Broad Institute, Cambridge, MA 02142; Brigham and Women\u2019s Hospital, Boston, MA 02112<span style=\"text-decoration: underline;\">; <\/span><sup>3<\/sup>Department of Neurology, Boston University School of Medicine, Boston, MA 02118<span style=\"text-decoration: underline;\">; <\/span><sup>4<\/sup>Advanced Tissue Resource Center, Harvard NeuroDiscovery Center, Charlestown, MA 02129<span style=\"text-decoration: underline;\">; <\/span><sup>5<\/sup>Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC 27710<span style=\"text-decoration: underline;\">; <\/span><sup>6<\/sup>Department of Biostatistics, Boston University School of Public Health and Boston University Clinical and Translational Science Institute, Boston, MA, 02118<\/li>\n<\/ul>\n<p><strong><span style=\"text-decoration: underline;\">Publications PUBLISHED:<\/span><\/strong><\/p>\n<ul>\n<li><a href=\"https:\/\/urldefense.proofpoint.com\/v2\/url?u=https-3A__www.ncbi.nlm.nih.gov_pubmed_27838321&amp;d=DgMFAg&amp;c=2rxEOw2KLbNB-I14iNYDhE3HM0YslhWt2FDmep0EPOI&amp;r=wXf9IMKUcD0GxK0qDtR-eMBPxD9t9uZWl7ma9NGVY7g&amp;m=R8MOu2qIFhmRcnqRYd6h2I2zjlu1Obv48nrJzryTzG4&amp;s=ilZP62fI9bFd7uhSZtdNe1hwatkSa_88TaOaS6Qy8VM&amp;e=\">Wang YH, Meyer RD, Bondzie PA, Jiang Y, Rahimi I, Rezazadeh K, Mehta M, Laver NM, Costello CE, Rahimi N. IGPR-1 Is Required for Endothelial Cell-Cell Adhesion and Barrier Function. \u00a0<em>J Mol Biol.<\/em><\/a><em> 2016 Nov 9. pii: S0022-2836(16)30472-7. doi: 10.1016\/j.jmb.2016.11.003. [Epub ahead of print]<\/em><\/li>\n<\/ul>\n<ul><\/ul>\n<p>The Department has been actively engaged in biobanking initiatives for several years. These important biobanking projects provide specimens to several investigators to help understand the basic mechanisms of disease. Banking these specimens also honors the patients\u2019 wishes to provide tissue for research.On behalf of the patients who donated biospecimens, and investigators who use the biospecimens, thank you. Your efforts ensure that pathology provides high quality biospecimens.Here is the impressive list of current and recent projects, including the pathology personnel that are participating in each project.<\/p>\n<p><strong>Biobanking grants in Pathology and Laboratory Medicine<\/strong><\/p>\n<p><strong><\/strong><\/p>\n<ul>\n<li style=\"text-align: left;\">2016-2018: Thrombosis in Cancer Patients (TCP). Pre-analytic Variables that May Impact Standardization,<\/li>\n<li>NCI. Contract award HHSN261200800001E\u00a0 &#8211; $1.4M total cost<\/li>\n<li>PI: Dr. Andry.<\/li>\n<li>Co-I: Drs. Stearns-Kurosawa, Kurosawa, Henderson, Sloane, &amp; Ms. Duffy, Sun<\/li>\n<li>Other personnel: Cheryl Spencer, Morgan Thompson<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<ul>\n<li>\u00a02016-2017: Boston Medical Center Biospecimen Source Site for the Clinical Proteomic Tumor\u00a0Analysis Consortium (CPTAC)<\/li>\n<li>NCI contract HHSN261201600011I &#8211; $89,229.07.<\/li>\n<li>PI: Dr. Andry<\/li>\n<li>Co-I: Henderson<\/li>\n<li>Other personnel: Spencer, Kim, Chen<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<ul>\n<li>2011-2017: Detection of Early Lung Cancer Among Military Personnel (DE-CAMP), pulmonary<\/li>\n<li>Department of Defense W81XWH-11-2-0161 &#8211; $2,378,826<\/li>\n<li>PI: Avrum Spira, M.D.<\/li>\n<li>\u00a0Co-I: Remick, Pistey<\/li>\n<li>Other personnel: Spencer<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<ul>\n<li>2016-present: Framingham Heart Study Biospecimen Core<\/li>\n<li>\u00a0Lab Director \u2013 Dr. Henderson<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<ul>\n<li>2014-2016: Biospecimen Source Site for Cancer Human Biospecimens (caHUB).<\/li>\n<li>NCI. Biospecimen Preanalytical Variables Program 11XS1007T1 &#8211; $332,508<\/li>\n<li>Co-I: Drs. Pistey, Henderson<\/li>\n<li>Other personnel: Spencer, Duffy<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<ul>\n<li>2014-2015: Biospecimen Source Site for the National Disease Research Interchange (NDRI)<\/li>\n<li>Biospecimen procurement contract &#8211; $14,600<\/li>\n<li>PI: Dr. Andry<\/li>\n<li>Other personnel: Bondzie, Spencer<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<ul>\n<li>2013-2015: Tissue Source Site for The Cancer Genome Atlas Project (TCGA)<\/li>\n<li>NCI. Initial Task Order 13XS114 \u2013 $15,350<\/li>\n<li>PI: Dr. Andry<\/li>\n<li>Co-I: Henderson<\/li>\n<li>Other personnel: Spencer, Mei Cao<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Pathology &amp; Laboratory Medicine News Items \u2013 November 2016 Announcements: Dr. Shinichiro Kurosawa has been reappointed to the Boston University Laboratory Safety Committee. The term of his appointment is through December 31, 2018 Dr. Chris Andry has had his appointment extend as Chair of the Boston University Laboratory Safety Committee. The term of his extension [&hellip;]<\/p>\n","protected":false},"author":939,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[1],"tags":[],"_links":{"self":[{"href":"https:\/\/www.bumc.bu.edu\/busm-pathology\/wp-json\/wp\/v2\/posts\/14235"}],"collection":[{"href":"https:\/\/www.bumc.bu.edu\/busm-pathology\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.bumc.bu.edu\/busm-pathology\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/busm-pathology\/wp-json\/wp\/v2\/users\/939"}],"replies":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/busm-pathology\/wp-json\/wp\/v2\/comments?post=14235"}],"version-history":[{"count":9,"href":"https:\/\/www.bumc.bu.edu\/busm-pathology\/wp-json\/wp\/v2\/posts\/14235\/revisions"}],"predecessor-version":[{"id":14248,"href":"https:\/\/www.bumc.bu.edu\/busm-pathology\/wp-json\/wp\/v2\/posts\/14235\/revisions\/14248"}],"wp:attachment":[{"href":"https:\/\/www.bumc.bu.edu\/busm-pathology\/wp-json\/wp\/v2\/media?parent=14235"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/busm-pathology\/wp-json\/wp\/v2\/categories?post=14235"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/busm-pathology\/wp-json\/wp\/v2\/tags?post=14235"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}