{"id":8439,"date":"2014-08-05T06:06:46","date_gmt":"2014-08-05T10:06:46","guid":{"rendered":"https:\/\/www.bumc.bu.edu\/busm-pathology\/?page_id=8439"},"modified":"2016-05-09T09:55:54","modified_gmt":"2016-05-09T13:55:54","slug":"walther-m-pfeifer-md","status":"publish","type":"page","link":"https:\/\/www.bumc.bu.edu\/busm-pathology\/home\/people_main\/walther-m-pfeifer-md\/","title":{"rendered":"Walther M. Pfeifer, MD"},"content":{"rendered":"

\"www.image-size.com\"<\/a><\/p>\n

 <\/p>\n

 <\/p>\n

Adjunct Assistant Professor
\nPathology & Laboratory Medicine
\nBoston University School of Medicine<\/p>\n

Lab Director, East Side Clinical Laboratory
\nSonic Healthcare
\nEast Providence, RI<\/p>\n

Education\/Training –<\/strong><\/h3>\n\n\n\n\n\n\n\n\n\n
1994 – 1995<\/td>\nInternal Medicine, Medizinische Poliklinik, University of Wuerzburg, Germany<\/td>\n<\/tr>\n
1996 – 1997<\/td>\nAnatomic Pathology, Medizinische Hochschule Hannover, Germany<\/td>\n<\/tr>\n
1997 – 1999<\/td>\nResearch Fellow, Experimental Pathology, Beth Israel Hospital, Boston, MA<\/td>\n<\/tr>\n
1999 – 2001<\/td>\nAnatomic Pathology, University of Wuerzburg, Germany<\/td>\n<\/tr>\n
2002 – 2005<\/td>\nResidency in Anatomic and Clinical Pathology, Beth Israel Deaconess Medical Center, Boston, MA<\/td>\n<\/tr>\n
2006 – 2006<\/td>\nClinical Fellow in Pediatric Pathology, Children’s Hospital, Boston, MA<\/td>\n<\/tr>\n
2006 – 2007<\/td>\nClinical Fellow in Hematopathology, Beth Israel Deaconess Medical Center, Boston, MA<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Board Certifications –<\/h3>\n

Anatomic and Clinical Pathology, 2007<\/p>\n

Hematopathology, 2008<\/p>\n

American Board of Pathology<\/em><\/p>\n

Membership in Professional Societies –<\/h3>\n
    \n
  • 2003 United States and Canadian Academy of Pathology<\/li>\n
  • 2003 American Society of Clinical Pathologists<\/li>\n
  • 2004 College of American Pathologists<\/li>\n
  • 2007 Massachusetts Medical Society<\/li>\n<\/ul>\n

    Research Interests –<\/h3>\n
      \n
    • Hematopathology<\/li>\n
    • Vascular Pathology<\/li>\n<\/ul>\n

      Recent Publications –<\/h3>\n
        \n
      • Pfeifer W<\/strong>, Levi E, Petrogiannis-Haliotis T, Lehmann L, Wang Z, Kadin ME. A murine xenograft model for human CD30+ anaplastic large cell lymphoma – successful growth inhibition with an anti-CD30 antibody (HeFi-1). Am J Pathol 1999; 155(4):1353-9.<\/li>\n
      • Schiemann WP, Pfeifer WM<\/strong>, Levi E, Kadin ME, Lodish HF. A deletion in the gene for transforming growth factor beta in a cutaneous T-cell lymphoma. Blood 1999; 15;94(8):2854-61.<\/li>\n
      • Levi E, Wang Z, Petrogiannis-Haliotis T, Pfeifer WM<\/strong>, Kempf W, Drews R, Kadin ME. Distinct effects of CD30 and Fas signalling in cutaneous anaplastic lymphomas: a possible mechanism for disease progression. J Invest Dermatol 2000; 115(6):1034-40.<\/li>\n
      • Mueller-Hermelink HK, Zettl A, Pfeifer W<\/strong>, Ott G. Pathology of lymphoma progression. Histopathology 2001; 38(4):285-306.<\/li>\n
      • Griesser H, Rauschert C, Pfeifer W<\/strong>, Monir H, Renner TJ, Embaye U, Neumann M. Different cell reactions upon stimulation of similar surface receptors: CD30 signaling in neoplastic T cell lines. Verh Dtsch Ges Zyt 2001; 22:114-122.<\/li>\n
      • Levi E, Pfeifer WM<\/strong>, Kadin ME. CD30-activation-mediated growth inhibition of anaplastic large-cell lymphoma cell lines: apoptosis or cell cycle arrest? Blood (letter) 2001; 98(5).<\/li>\n
      • Kempf W, Levi E, Kamarashev J, Kutzner H, Pfeifer W<\/strong>, Petrogiannis-Haliotis T, Burg G, Kadin ME. Fascin expression in CD30-positive cutaneous lymphoproliferative disorders. J Cutan Pathol 2002 May;29(5):295-300.<\/li>\n
      • Schiemann WP, Rotzer D, Pfeifer WM<\/strong>, Levi E, Rai KR, Knaus P, Kadin ME. Transforming growth factor-beta (TGF-beta)-resistant B cells from chronic lymphocytic leukemia patients contain recurrent mutations in the signal sequence of the type I TGF-beta receptor. Cancer Detect Prev 2004;28(1):57-64.<\/li>\n
      • Horn T, Kremer M, Dechow T, Pfeifer WM<\/strong>, Geist B, Perker M, Duyster J, Quintilla-Martinez L, Fend F. Detection of the activating JAK2 V617F mutation in paraffin-embedded trephine bone marrow biopsies of patients with chronic myeloproliferative diseases. J Mol Diagn. 2006 July;8(3):299-304.<\/li>\n
      • Maithel SK, Pratt W, Kelleher T, Avigan D, Goldman H, Pfeifer W<\/strong>, Pihan GA. Autoimmune pancreatitis in the setting of Castleman’s disease. Pancreas 2007 Nov:(35(4):384-7.<\/li>\n
      • Kremer M, Horn T, Koch I, Dechow T, Gattenloehner S, Pfeifer W<\/strong>, Quintanilla-Martinez L, Fend F. Qantitation of the JAK2V617F mutation in microdissected bone marrow trephines: equal mutational load in myeloid lineages and rare involvement of lymphoid cells. Am J Surg Pathol 2008 Jun;32(6):928-35.<\/li>\n<\/ul>\n

        Selected Abstracts –<\/h3>\n
          \n
        1. Pfeifer W<\/strong>, Levi E, Petrogiannis-Haliotis T, Zhenxi W, Kadin ME. Cytokine expression of CD30+ anaplastic large cell lymphoma cell lines – comparison of nodal versus cutaneous ALCL. United States and Canadian Academy of Pathology, San Francisco, 1999. Poster presentation.<\/li>\n
        2. Pfeifer W<\/strong>, Levi E, Petrogiannis-Haliotis T, Zhenxi W, Kadin ME. Ki 1+ anaplastic large cell lymphoma expressing the t(2;5) translocation in triple immuno-deficient (SCID BEIGE) mice. German Society of Pathology, Jena, 1999. Platform presentation.<\/li>\n
        3. Pfeifer W<\/strong>, Monir M, Neumann M, Berberich H, Griesser H. CD30 mutations and abnormal signal transduction in Hodgkin`s disease (HD)- and large cell anaplastic lymphoma (LCAL)-related cell lines. European Association of Hematopathology, London, 2000. Poster presentation.<\/li>\n
        4. Pfeifer W<\/strong>, Vogel P, Griesser H. Analysis of cytokeratin 20 as a potential marker of malignancy. German Society of Pathology, Kiel, 2000. Platform presentation.<\/li>\n
        5. Pfeifer W<\/strong>, Bryan B, Avigan D, Pihan G. Osteosclerotic\/ myelofibrotic chronic myelogenous leukemia (CML) at presentation: A rare and possibly unique subset of CML. International Academy of Pathology, Athens, 2008, Poster presentation.<\/li>\n
        6. Pfeifer W<\/strong>, Vakil H, Kurrer M, Levi E. Phosphorylation Status of retinoblastoma protein predicts survival in rituxan-treated follicular lymphomas. International Academy of Pathology, Athens, 2008, Poster presentation.<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"

              Adjunct Assistant Professor Pathology & Laboratory Medicine Boston University School of Medicine Lab Director, East Side Clinical Laboratory Sonic Healthcare East Providence, RI Education\/Training – 1994 – 1995 Internal Medicine, Medizinische Poliklinik, University of Wuerzburg, Germany 1996 – 1997 Anatomic Pathology, Medizinische Hochschule Hannover, Germany 1997 – 1999 Research Fellow, Experimental Pathology, Beth […]<\/p>\n","protected":false},"author":1111,"featured_media":0,"parent":3281,"menu_order":89,"comment_status":"closed","ping_status":"closed","template":"profiles.php","meta":[],"_links":{"self":[{"href":"https:\/\/www.bumc.bu.edu\/busm-pathology\/wp-json\/wp\/v2\/pages\/8439"}],"collection":[{"href":"https:\/\/www.bumc.bu.edu\/busm-pathology\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.bumc.bu.edu\/busm-pathology\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/busm-pathology\/wp-json\/wp\/v2\/users\/1111"}],"replies":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/busm-pathology\/wp-json\/wp\/v2\/comments?post=8439"}],"version-history":[{"count":15,"href":"https:\/\/www.bumc.bu.edu\/busm-pathology\/wp-json\/wp\/v2\/pages\/8439\/revisions"}],"predecessor-version":[{"id":13884,"href":"https:\/\/www.bumc.bu.edu\/busm-pathology\/wp-json\/wp\/v2\/pages\/8439\/revisions\/13884"}],"up":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/busm-pathology\/wp-json\/wp\/v2\/pages\/3281"}],"wp:attachment":[{"href":"https:\/\/www.bumc.bu.edu\/busm-pathology\/wp-json\/wp\/v2\/media?parent=8439"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}