{"id":1766,"date":"2010-09-02T14:07:00","date_gmt":"2010-09-02T18:07:00","guid":{"rendered":"https:\/\/www.bumc.bu.edu\/busm-pathology\/?page_id=1766"},"modified":"2015-06-03T11:30:55","modified_gmt":"2015-06-03T15:30:55","slug":"dominic-beal","status":"publish","type":"page","link":"https:\/\/www.bumc.bu.edu\/busm-pathology\/home\/people_main\/dominic-beal\/","title":{"rendered":"Dominic Beal"},"content":{"rendered":"<p><a href=\"\/busm-pathology\/files\/2008\/11\/dbeal.jpg\"><img loading=\"lazy\" class=\"alignnone size-full wp-image-596\" title=\"dbeal\" src=\"\/busm-pathology\/files\/2008\/11\/dbeal.jpg\" alt=\"dbeal\" width=\"164\" height=\"227\" \/><\/a><\/p>\n<h3>EDUCATION<\/h3>\n<ul>\n<li> September 2008 &#8211; present:\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 PhD\u00a0 Program \u2013 Department of Pathology and Laboratory Medicine<br \/>\nBoston University School of Medicine, Boston, MA<br \/>\nDr. Daniel Remick Lab \u2013 Advisor<\/li>\n<li>2006:\u00a0\u00a0 Master of Science (Immunology of Infectious Disease)<br \/>\nLondon School of Hygiene and Tropical Medicine; England<\/li>\n<li>2004:\u00a0\u00a0\u00a0 Master of Arts (Natural Sciences &#8211; Pathology)<br \/>\nUniversity of Cambridge: Cambridge, England<\/li>\n<li>2000:\u00a0\u00a0\u00a0\u00a0 GCSE and Advanced Level<br \/>\nEastbourne College: Eastbourne, England<\/li>\n<\/ul>\n<h3>RESEARCH INTERESTS<\/h3>\n<p style=\"padding-left: 30px;\">Asthma immunology, immune regulation, T-cell subsets<\/p>\n<h3>PUBLICATIONS<\/h3>\n<ul>\n<li>Infection with &#8220;escaped&#8221; virus variants impairs control of simian immunodeficiency virus SIVmac239 replication in Mamu-B*08-positive macaques. Valentine LE, Loffredo JT, Bean AT, Le\u00f3n EJ, MacNair CE, <strong>Beal DR<\/strong>, Piaskowski SM, Klimentidis YC, Lank SM, Wiseman RW, Weinfurter JT, May GE, Rakasz EG, Wilson NA, Friedrich TC, O&#8217;Connor DH, Allison DB, Watkins DI.\u00a0 J Virol. 2009 Nov;83(22):11514-27<\/li>\n<li> Two MHC class I molecules associated with elite control of immunodeficiency virus replication, Mamu-B*08 and HLA-B*2705, bind peptides with sequence similarity. Loffredo JT, Sidney J, Bean AT, <strong>Beal DR<\/strong>, Bardet W, Wahl A, Hawkins OE, Piaskowski S, Wilson NA, Hildebrand WH, Watkins DI, Sette A. J Immunol. 2009 Jun 15;182(12):7763-75<\/li>\n<li> Patterns of CD8+ immunodominance may influence the ability of Mamu-B*08-positive macaques to naturally control simian immunodeficiency virus SIVmac239 replication. Loffredo JT, Bean AT, <strong>Beal DR<\/strong>, Le\u00f3n EJ, May GE, Piaskowski SM, Furlott JR, Reed J, Musani SK, Rakasz EG, Friedrich TC, Wilson NA, Allison DB, Watkins DI. J Virol. 2008 Feb;82(4):1723-38<\/li>\n<li>CD8+ T cells from SIV elite controller macaques recognize Mamu-B*08-bound epitopes and select for widespread viral variation. Loffredo JT, Friedrich TC, Le\u00f3n EJ, Stephany JJ, Rodrigues DS, Spencer SP, Bean AT, <strong>Beal DR<\/strong>, Burwitz BJ, Rudersdorf RA, Wallace LT, Piaskowski SM, May GE, Sidney J, Gostick E, Wilson NA, Price DA, Kallas EG, Piontkivska H, Hughes AL, Sette A, Watkins DI. PLoS One. 2007 Nov 14;2(11):e1152<\/li>\n<li>Mamu-B*08-positive macaques control simian immunodeficiency virus replication. Loffredo JT, Maxwell J, Qi Y, Glidden CE, Borchardt GJ, Soma T, Bean AT,<strong> Beal DR<\/strong>, Wilson NA, Rehrauer WM, Lifson JD, Carrington M, Watkins DI. J Virol. 2007 Aug;81(16):8827-32<\/li>\n<li>The development of tolerance to Clostridium perfringens type D epsilon-toxin in MDCK and G-402 cells. <strong>Beal DR<\/strong>, Titball RW, Lindsay CD. Hum Exp Toxicol. 2003 Nov;22(11):593-605<\/li>\n<\/ul>\n<h3>MEMBERSHIPS IN ORGANIZATIONS<\/h3>\n<ul>\n<li>Member of GMSSO at Boston University<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>EDUCATION September 2008 &#8211; present:\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 PhD\u00a0 Program \u2013 Department of Pathology and Laboratory Medicine Boston University School of Medicine, Boston, MA Dr. Daniel Remick Lab \u2013 Advisor 2006:\u00a0\u00a0 Master of Science (Immunology of Infectious Disease) London School of Hygiene and Tropical Medicine; England 2004:\u00a0\u00a0\u00a0 Master of Arts (Natural Sciences &#8211; Pathology) University of Cambridge: Cambridge, [&hellip;]<\/p>\n","protected":false},"author":1131,"featured_media":0,"parent":3281,"menu_order":70,"comment_status":"closed","ping_status":"open","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/www.bumc.bu.edu\/busm-pathology\/wp-json\/wp\/v2\/pages\/1766"}],"collection":[{"href":"https:\/\/www.bumc.bu.edu\/busm-pathology\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.bumc.bu.edu\/busm-pathology\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/busm-pathology\/wp-json\/wp\/v2\/users\/1131"}],"replies":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/busm-pathology\/wp-json\/wp\/v2\/comments?post=1766"}],"version-history":[{"count":4,"href":"https:\/\/www.bumc.bu.edu\/busm-pathology\/wp-json\/wp\/v2\/pages\/1766\/revisions"}],"predecessor-version":[{"id":11923,"href":"https:\/\/www.bumc.bu.edu\/busm-pathology\/wp-json\/wp\/v2\/pages\/1766\/revisions\/11923"}],"up":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/busm-pathology\/wp-json\/wp\/v2\/pages\/3281"}],"wp:attachment":[{"href":"https:\/\/www.bumc.bu.edu\/busm-pathology\/wp-json\/wp\/v2\/media?parent=1766"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}