{"id":19230,"date":"2025-07-30T12:22:59","date_gmt":"2025-07-30T16:22:59","guid":{"rendered":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/?post_type=profile&#038;p=19230"},"modified":"2025-12-19T16:32:59","modified_gmt":"2025-12-19T21:32:59","slug":"linnea-saunders","status":"publish","type":"profile","link":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/profiles\/linnea-saunders\/","title":{"rendered":"Linnea Saunders"},"content":{"rendered":"<p>Originally from New Hampshire, I attended Proctor Academy and developed a love of science from my high school coursework. Unable to decide whether I liked my chemistry or biology courses better, I chose both, majoring in Biochemistry at the University of Vermont. While at the University of Vermont I completed an undergraduate thesis project in the Hondal Lab, developing an affinity chromatography resin that can selectively bind proteins with thiol modifications, and elute them without removing those thiol modifications.<br \/>\nI knew when I finished college that I intended to pursue my PhD, but I wanted more experiences in scientific research before starting my PhD. After graduating, I moved to Boston and started working at Entrada Therapeutics in downstream protein purification, purifying recombinant antibody fragments from E. coli and yeast. A year later, I left Entrada for a role at Repertoire Immune Medicines, where I joined the yeast display team, leveraging yeast display to affinity mature TCRs against novel tumor-antigens. My industry experience fostered a passion for disease-focused research, with the hope of discovering new potential targets for therapeutics.<\/p>\n<p>Having always harbored an interest in prion diseases since learning about them in my AP Biology class, I entered BU hoping to find a lab researching neurodegenerative disorders. I joined Dr. David Harris\u2019 lab in the summer of 2025, where I am now investigating mechanisms of resistance to genetic CJD.<\/p>\n","protected":false},"author":8106,"template":"","tags":[],"_links":{"self":[{"href":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/wp-json\/wp\/v2\/profile\/19230"}],"collection":[{"href":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/wp-json\/wp\/v2\/profile"}],"about":[{"href":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/wp-json\/wp\/v2\/types\/profile"}],"author":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/wp-json\/wp\/v2\/users\/8106"}],"version-history":[{"count":2,"href":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/wp-json\/wp\/v2\/profile\/19230\/revisions"}],"predecessor-version":[{"id":19358,"href":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/wp-json\/wp\/v2\/profile\/19230\/revisions\/19358"}],"wp:attachment":[{"href":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/wp-json\/wp\/v2\/media?parent=19230"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/wp-json\/wp\/v2\/tags?post=19230"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}