{"id":18822,"date":"2024-06-13T10:13:43","date_gmt":"2024-06-13T14:13:43","guid":{"rendered":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/?post_type=profile&#038;p=18822"},"modified":"2025-12-22T09:57:47","modified_gmt":"2025-12-22T14:57:47","slug":"jose-andres-alepuz-guillen","status":"publish","type":"profile","link":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/profiles\/jose-andres-alepuz-guillen\/","title":{"rendered":"Jose Andres Alepuz Guillen"},"content":{"rendered":"<p>I am currently a Postdoctoral Researcher in the laboratory of Dr. David A. Harris in the Department of Biochemistry at Boston University School of Medicine. I hold a B.Sc. Biochemistry from Queen Mary University of London, a M.Sc. from King&#8217;s College London and a Ph.D. from the School of Molecular Biosciences at the University of Glasgow, where I studied at the Institute for Translational Pharmacology under the guidance of Prof. Andrew B. Tobin and Prof. Graeme Milligan. During my doctoral work, I investigated the potential role of the M1 muscarinic acetylcholine receptor in misfolded protein propagation using primary neuronal cultures. My research at the Harris Lab is focused on Creutzfeldt-Jakob disease and the E200K PrP mutation utilizing iPSC-derived cells and primary neuronal and astrocyte cultures.<\/p>\n<p><span class=\"s1\"><div class=\"bu_collapsible_container \" aria-live=\"polite\" data-customize-animation=\"false\"><h4 class=\"bu_collapsible\" aria-expanded=\"false\"tabindex=\"0\" role=\"button\">Representative Publications<\/h4><div class=\"bu_collapsible_section\" style=\"display: none;\"><\/span><\/p>\n<p>Ashraf A, Alepuz Guillen JA, Aljuhani M, Hubens C, So PW. Low Cerebrospinal Fluid Levels of Melanotransferrin Are Associated With Conversion of Mild Cognitively Impaired Subjects to Alzheimer\u2019s Disease. Front Neurosci. 2019;13. PMID: 30906244<\/p>\n<p><span class=\"s1\"><\/div>\n<\/div>\n<\/span><\/p>\n","protected":false},"author":8106,"template":"","tags":[],"_links":{"self":[{"href":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/wp-json\/wp\/v2\/profile\/18822"}],"collection":[{"href":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/wp-json\/wp\/v2\/profile"}],"about":[{"href":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/wp-json\/wp\/v2\/types\/profile"}],"author":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/wp-json\/wp\/v2\/users\/8106"}],"version-history":[{"count":3,"href":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/wp-json\/wp\/v2\/profile\/18822\/revisions"}],"predecessor-version":[{"id":19514,"href":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/wp-json\/wp\/v2\/profile\/18822\/revisions\/19514"}],"wp:attachment":[{"href":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/wp-json\/wp\/v2\/media?parent=18822"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/wp-json\/wp\/v2\/tags?post=18822"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}