{"id":16314,"date":"2021-04-18T09:18:27","date_gmt":"2021-04-18T13:18:27","guid":{"rendered":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/?post_type=profile&p=16314"},"modified":"2025-02-09T07:09:47","modified_gmt":"2025-02-09T12:09:47","slug":"remi-janicot","status":"publish","type":"profile","link":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/profiles\/remi-janicot\/","title":{"rendered":"Remi Janicot"},"content":{"rendered":"

I was born in Paris (France) and grew up in Europe until I was 18. After graduating high school, I moved to America to pursue my passion for basketball while continuing high level studies. I played collegiate basketball and earned my bachelor’s at Ursinus College, a small school around Philadelphia where I graduated from in 2018. After that incredible experience, I worked at Johns Hopkins in Baltimore as a research assistant investigating mechanisms and treatments for pediatric epilepsy. Although I had obviously always been interested in science, my experience at Hopkins convinced me that I wanted to be a full-time researcher, which is what brought me into the exceptional BU research community.<\/span><\/p>\n

As a member of the Garcia-Marcos lab, the focus of my research is to investigate heterotrimeric G-proteins and their regulation. The clinical importance of this research is evident, as over 35% of FDA approved drugs target G-protein coupled receptors (GPCRs). The lab has established multiple models and developed tools to precisely measure G-protein activity in the cell. These tools can be used to develop a better understanding of how G-proteins get activated and regulated. While I did not have a biochemistry background before rotating in this lab, I was drawn by the clear pharmacological and clinical impacts that my research can have.<\/span><\/p>\n

Publications<\/strong><\/p>\n

Shao L-R, Janicot R & Stafstrom CE. 2021. Na+-K+-ATPase Functions in the Developing Hippocampus: Regional Differences in CA1 and CA3 Neuronal Excitability and Role in Synchronous Network Bursting. Journal of Neurophysiology, vol. 125(1), 1-11. doi: 10.1152\/jn.00453.2020<\/span><\/p>\n

Janicot R, Stafstrom CE & Shao L-R. 2020. The Efficacy of Fructose-1,6-Bisphosphate in Suppressing Status Epilepticus in Developing Rats. Epilepsy Research, vol. 168, 106500. doi: 10.1016\/j.eplepsyres.2020.106500<\/span><\/p>\n

Janicot R, Stafstrom CE & Shao L-R. 2020. 2-Deoxyglucose Terminates Pilocarpine-induced Status Epilepticus in Neonatal Rats. Epilepsia, vol. 61(7), 1528-37. doi: 10.1111\/epi.16583<\/span><\/p>\n

Janicot R, Shao L-R & Stafstrom CE. 2020. Infantile Spasms: An update on Pre-clinical Models and EEG Mechanisms. Children, vol. 7(1), 5. doi: 10.3390\/children7010005<\/span><\/p>\n

Loomis C, Stephens A, Janicot R, Baqai U, Drebushenko L & Round J. 2020. Identification of MAGUK scaffold proteins as intracellular binding partners of synaptic adhesion protein Slitrk2. Molecular and Cellular Neuroscience, vol. 103, 103465. doi: 10.1016\/j.mcn.2019.103465<\/span><\/p>\n","protected":false},"author":1191,"template":"","tags":[],"_links":{"self":[{"href":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/wp-json\/wp\/v2\/profile\/16314"}],"collection":[{"href":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/wp-json\/wp\/v2\/profile"}],"about":[{"href":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/wp-json\/wp\/v2\/types\/profile"}],"author":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/wp-json\/wp\/v2\/users\/1191"}],"version-history":[{"count":1,"href":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/wp-json\/wp\/v2\/profile\/16314\/revisions"}],"predecessor-version":[{"id":16315,"href":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/wp-json\/wp\/v2\/profile\/16314\/revisions\/16315"}],"wp:attachment":[{"href":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/wp-json\/wp\/v2\/media?parent=16314"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/wp-json\/wp\/v2\/tags?post=16314"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}