{"id":19635,"date":"2026-01-15T14:19:35","date_gmt":"2026-01-15T19:19:35","guid":{"rendered":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/?p=19635"},"modified":"2026-01-15T14:19:35","modified_gmt":"2026-01-15T19:19:35","slug":"new-research-from-the-grishok-lab-spermatogenic-argonaute-proteins-are-activated-by-insulin-igf-1-signaling-and-promote-aging-in-c-elegans","status":"publish","type":"post","link":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/2026\/01\/15\/new-research-from-the-grishok-lab-spermatogenic-argonaute-proteins-are-activated-by-insulin-igf-1-signaling-and-promote-aging-in-c-elegans\/","title":{"rendered":"New research from the Grishok Lab: spermatogenic Argonaute proteins are activated by Insulin\/IGF-1 Signaling and promote aging in C. elegans"},"content":{"rendered":"<div class=\"x_elementToProof\" data-olk-copy-source=\"MessageBody\">January 12, 2026<\/div>\n<div data-olk-copy-source=\"MessageBody\"><\/div>\n<h3 class=\"x_elementToProof\">New research from the Grishok Lab: spermatogenic Argonaute proteins are activated by Insulin\/IGF-1 Signaling and promote aging in<span>\u00a0<\/span><i>C. elegans<\/i><\/h3>\n<div><\/div>\n<div class=\"x_elementToProof\">Published in EMBO Reports on January 8<sup>th<\/sup>\u00a02026.<\/div>\n<p><img loading=\"lazy\" src=\"\/biochemcellbio\/files\/2026\/01\/Synopsis_graphical_abstract-1024x822.png\" alt=\"\" width=\"208\" height=\"167\" class=\"alignleft  wp-image-19636\" srcset=\"https:\/\/www.bumc.bu.edu\/biochemcellbio\/files\/2026\/01\/Synopsis_graphical_abstract-1024x822.png 1024w, https:\/\/www.bumc.bu.edu\/biochemcellbio\/files\/2026\/01\/Synopsis_graphical_abstract-374x300.png 374w, https:\/\/www.bumc.bu.edu\/biochemcellbio\/files\/2026\/01\/Synopsis_graphical_abstract-768x617.png 768w, https:\/\/www.bumc.bu.edu\/biochemcellbio\/files\/2026\/01\/Synopsis_graphical_abstract-1536x1234.png 1536w, https:\/\/www.bumc.bu.edu\/biochemcellbio\/files\/2026\/01\/Synopsis_graphical_abstract-2048x1645.png 2048w\" sizes=\"(max-width: 208px) 100vw, 208px\" \/><\/p>\n<div><\/div>\n<div class=\"x_elementToProof\"><u><a id=\"OWA5d23f2e4-ce40-75c8-6212-498b77485cb6\" class=\"x_OWAAutoLink\" data-auth=\"NotApplicable\" href=\"https:\/\/link.springer.com\/article\/10.1038\/s44319-025-00682-4\" data-linkindex=\"0\" title=\"https:\/\/link.springer.com\/article\/10.1038\/s44319-025-00682-4\">https:\/\/link.springer.com\/article\/10.1038\/s44319-025-00682-4<\/a><\/u><\/div>\n<div class=\"x_elementToProof\" aria-hidden=\"true\"><\/div>\n<div aria-hidden=\"true\"><\/div>\n<div><\/div>\n<div><\/div>\n<div><\/div>\n<div><\/div>\n<div>This work from the Grishok laboratory was co-authored by a GPGG Graduate Student Thomas Liontis, BU undergraduates Valentina Pannarale and Sasiru Pathiranage, and a former summer high school student Jeeya Patel.<\/div>\n","protected":false},"excerpt":{"rendered":"<p>January 12, 2026 New research from the Grishok Lab: spermatogenic Argonaute proteins are activated by Insulin\/IGF-1 Signaling and promote aging [&hellip;]<\/p>\n","protected":false},"author":8106,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[104,4666],"tags":[],"_links":{"self":[{"href":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/wp-json\/wp\/v2\/posts\/19635"}],"collection":[{"href":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/wp-json\/wp\/v2\/users\/8106"}],"replies":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/wp-json\/wp\/v2\/comments?post=19635"}],"version-history":[{"count":5,"href":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/wp-json\/wp\/v2\/posts\/19635\/revisions"}],"predecessor-version":[{"id":19642,"href":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/wp-json\/wp\/v2\/posts\/19635\/revisions\/19642"}],"wp:attachment":[{"href":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/wp-json\/wp\/v2\/media?parent=19635"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/wp-json\/wp\/v2\/categories?post=19635"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/wp-json\/wp\/v2\/tags?post=19635"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}