{"id":18230,"date":"2023-04-27T14:06:28","date_gmt":"2023-04-27T18:06:28","guid":{"rendered":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/?p=18230"},"modified":"2026-01-07T15:12:41","modified_gmt":"2026-01-07T20:12:41","slug":"perissi-lab-awarded-a-new-nigms-maximizing-investigators-research-award-mira","status":"publish","type":"post","link":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/2023\/04\/27\/perissi-lab-awarded-a-new-nigms-maximizing-investigators-research-award-mira\/","title":{"rendered":"Perissi Lab awarded a new NIGMS Maximizing Investigator&#8217;s Research Award (MIRA)"},"content":{"rendered":"<p>The Perissi Lab has received a new NIGMS Maximizing Investigator&#8217;s Research Award (MIRA) to investigate the &#8220;Coordination of PAR and Ub signaling in mitochondria&#8221;. Research supported by the R35GM149339 award will investigate the spatial and functional regulation of mitochondria retrograde signaling in response to mitochondrial stress and explore the crosstalk between ubiquitination and ADP-ribosylation in regulating mitochondrial homeostasis.\u00a0 Successful completion of the proposed studies will lead to a better understanding of the mechanisms regulating metabolic adaptation to mitochondrial stress and possibly reveal novel pathways to target for therapeutic purposes.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The Perissi Lab has received a new NIGMS Maximizing Investigator&#8217;s Research Award (MIRA) to investigate the &#8220;Coordination of PAR and [&hellip;]<\/p>\n","protected":false},"author":8106,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[104,4665,1],"tags":[],"_links":{"self":[{"href":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/wp-json\/wp\/v2\/posts\/18230"}],"collection":[{"href":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/wp-json\/wp\/v2\/users\/8106"}],"replies":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/wp-json\/wp\/v2\/comments?post=18230"}],"version-history":[{"count":2,"href":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/wp-json\/wp\/v2\/posts\/18230\/revisions"}],"predecessor-version":[{"id":18232,"href":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/wp-json\/wp\/v2\/posts\/18230\/revisions\/18232"}],"wp:attachment":[{"href":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/wp-json\/wp\/v2\/media?parent=18230"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/wp-json\/wp\/v2\/categories?post=18230"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/wp-json\/wp\/v2\/tags?post=18230"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}