{"id":18189,"date":"2023-04-03T10:19:46","date_gmt":"2023-04-03T14:19:46","guid":{"rendered":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/?p=18189"},"modified":"2026-01-07T15:12:44","modified_gmt":"2026-01-07T20:12:44","slug":"robert-mercer-recently-awarded-a-research-grant-funded-by-creutzfeldt-jakob-disease-foundation","status":"publish","type":"post","link":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/2023\/04\/03\/robert-mercer-recently-awarded-a-research-grant-funded-by-creutzfeldt-jakob-disease-foundation\/","title":{"rendered":"Robert Mercer recently awarded a research grant funded by Creutzfeldt-Jakob Disease Foundation."},"content":{"rendered":"<p><img loading=\"lazy\" src=\"\/biochemcellbio\/files\/2020\/04\/DSC_4377.jpg\" alt=\"\" width=\"154\" height=\"210\" class=\"wp-image-15309 alignleft\" srcset=\"https:\/\/www.bumc.bu.edu\/biochemcellbio\/files\/2020\/04\/DSC_4377.jpg 850w, https:\/\/www.bumc.bu.edu\/biochemcellbio\/files\/2020\/04\/DSC_4377-219x300.jpg 219w, https:\/\/www.bumc.bu.edu\/biochemcellbio\/files\/2020\/04\/DSC_4377-768x1050.jpg 768w, https:\/\/www.bumc.bu.edu\/biochemcellbio\/files\/2020\/04\/DSC_4377-749x1024.jpg 749w\" sizes=\"(max-width: 154px) 100vw, 154px\" \/>Robert Mercer,\u00a0an Instructor in the Harris lab, was recently awarded a research grant funded by Creutzfeldt-Jakob Disease Foundation. This two-year, $100,000 grant is entitled \u201cMicroenvironment mapping of the PrP<sup>Sc<\/sup>\u00a0Interactome\u201d.<\/p>\n<p>Prion diseases are fatal and currently untreatable neurodegenerative diseases of humans and animals. The central event underlying these diseases is the 3D conversion of the prion protein (PrP<sup>C<\/sup>) to a pathogenic shape, denoted PrP<sup>Sc<\/sup>. In attempts to elucidate its function, there have been multiple studies analyzing the interaction network, or interactome, of\u00a0PrP<sup>C<\/sup>. However, almost nothing is known about the interaction network of\u00a0PrP<sup>Sc<\/sup>. Here, we propose to examine the PrP<sup>Sc<\/sup>\u00a0interactome for the first time, providing a wealth of new targets for therapeutic intervention.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Robert Mercer,\u00a0an Instructor in the Harris lab, was recently awarded a research grant funded by Creutzfeldt-Jakob Disease Foundation. This two-year, [&hellip;]<\/p>\n","protected":false},"author":8106,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[104,4658,100],"tags":[],"_links":{"self":[{"href":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/wp-json\/wp\/v2\/posts\/18189"}],"collection":[{"href":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/wp-json\/wp\/v2\/users\/8106"}],"replies":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/wp-json\/wp\/v2\/comments?post=18189"}],"version-history":[{"count":3,"href":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/wp-json\/wp\/v2\/posts\/18189\/revisions"}],"predecessor-version":[{"id":18192,"href":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/wp-json\/wp\/v2\/posts\/18189\/revisions\/18192"}],"wp:attachment":[{"href":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/wp-json\/wp\/v2\/media?parent=18189"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/wp-json\/wp\/v2\/categories?post=18189"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/wp-json\/wp\/v2\/tags?post=18189"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}