{"id":16320,"date":"2021-04-20T10:29:09","date_gmt":"2021-04-20T14:29:09","guid":{"rendered":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/?p=16320"},"modified":"2026-01-07T15:13:40","modified_gmt":"2026-01-07T20:13:40","slug":"grant-award-dod-discovery-award-identification-of-receptors-for-tar-dna-binding-protein-43-tdp-43-that-mediate-cellular-uptake-and-neurotoxicity","status":"publish","type":"post","link":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/2021\/04\/20\/grant-award-dod-discovery-award-identification-of-receptors-for-tar-dna-binding-protein-43-tdp-43-that-mediate-cellular-uptake-and-neurotoxicity\/","title":{"rendered":"Grant Award: Department of Defense, Discovery Award"},"content":{"rendered":"

\"\"<\/p>\n

Robert Mercer<\/a>, a Postdoctoral Associate in the Harris Lab<\/a>, was recently awarded a Discovery Award research grant funded by the Department of Defense. This two-year, $200,000 grant is entitled \u201c Identification of Receptors for TAR DNA-binding Protein 43 (TDP-43) That Mediate Cellular Uptake and Neurotoxicity \u201d. This project aims to identify the cellular receptors of the pathological TDP-43 assemblies found in the brains of patients with\u00a0 Amyotrophic Lateral Sclerosis (ALS), Frontotemporal Lobar Degeneration (FTLD), and Chronic Traumatic Encephalopathy (CTE). The identification of these receptors will provide novel therapeutic targets to combat these devastating and currently untreatable diseases.<\/p>\n","protected":false},"excerpt":{"rendered":"

Robert Mercer, a Postdoctoral Associate in the Harris Lab, was recently awarded a Discovery Award research grant funded by the […]<\/p>\n","protected":false},"author":8106,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[104,102,4658],"tags":[],"_links":{"self":[{"href":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/wp-json\/wp\/v2\/posts\/16320"}],"collection":[{"href":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/wp-json\/wp\/v2\/users\/8106"}],"replies":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/wp-json\/wp\/v2\/comments?post=16320"}],"version-history":[{"count":2,"href":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/wp-json\/wp\/v2\/posts\/16320\/revisions"}],"predecessor-version":[{"id":16322,"href":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/wp-json\/wp\/v2\/posts\/16320\/revisions\/16322"}],"wp:attachment":[{"href":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/wp-json\/wp\/v2\/media?parent=16320"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/wp-json\/wp\/v2\/categories?post=16320"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/wp-json\/wp\/v2\/tags?post=16320"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}