{"id":16508,"date":"2021-08-31T14:45:13","date_gmt":"2021-08-31T18:45:13","guid":{"rendered":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/?page_id=16508"},"modified":"2026-03-16T19:02:51","modified_gmt":"2026-03-16T23:02:51","slug":"publications","status":"publish","type":"page","link":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/varelaslab\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"

Complete List of Published Work in MyBibliography<\/a><\/p>\n

2026<\/h3>
<\/p>\n

A highly resolved integrated single-cell atlas of HPV-negative head and neck cancer.<\/a><\/strong> Kroehling L, Chen A, Spinella A, Reed E, Kukuruzinska M, Varelas X, Monti S. Commun Med<\/strong><\/span> (Lond). 2026 Mar 11;6(1):138. doi: 10.1038\/s43856-026-01401-3. PMID: 41813916<\/span><\/span><\/span><\/p>\n

Up-regulation of an epithelial miRNA is associated with immune evasion in progressive bronchial premalignant lesions.<\/a><\/strong> Ning B, Chiu DJ, Pfefferkorn RM, Cullinane E, Kefella Y, Kane E, Reyes-Ortiz V, Liu G, Zhang X, Liu H, Sultan L, Green E, Constant M, Spira AE, Campbell JD, Reid ME, Varelas X, Burks EJ, Lenburg ME, Mazzilli SA, Beane JE. Cancer Immunol Res<\/strong><\/span>. 2026 Feb 11. doi: 10.1158\/2326-6066.CIR-25-0431. PMID: 41670462<\/span><\/span><\/span><\/p>\n

Inhibitory probes for spatiotemporal analysis of G\u03b1s protein signaling.<\/a><\/strong> Zhao J, Luebbers A, Savransky S, Lin TY, Cheng N, Wilcox A, Janicot R, Green E, Sharma A, Maziarz M, Varelas X, Irannejad R, Vilardaga JP, Garcia-Marcos M. Nat Chem Biol.<\/strong><\/span> 2026 Feb 3. doi: 10.1038\/s41589-025-02138-1. PMID: 41634441<\/span><\/span><\/span><\/p>\n

LSD1 Inhibition Induces MHC-I and Dendritic Cell Activation to Promote Antitumor Immunity in Head and Neck Squamous Cell Carcinoma.<\/a><\/strong> Chakraborty AK, Kroehling L, Raut RD, Choudhury C, Kukuruzinska MA, Gutkind JS, Varelas X, Sahay B, Monti S, Bais MV. Cancer Res<\/strong><\/span>. 2026 Jan 16;86(2):503-518. doi: 10.1158\/0008-5472.CAN-24-3239. PMID: 41066547<\/span><\/span><\/span><\/p>\n

A large-scale balloon model of confluent cells validates stress inference from geometry.<\/a><\/strong> Hall JK, Deng Y, Kontodimas K, Nia H, Varelas X, Lutchen KR, Bates J, Suki B. NPJ Biol Phys Mech<\/strong><\/span>. 2026;3(1):1. doi: 10.1038\/s44341-025-00031-5. Epub 2026 Jan 7. PMID: 41523857<\/span><\/span><\/span><\/p>\n

Airway Goblet Metaplasia Resulting from YAP\/TAZ Deletion Drives Pulmonary Inflammatory Responses.<\/a><\/strong> Cheng N, Kontodimas K, Matschulat A, Hicks-Berthet J, Varelas X. Am J Respir Cell Mol Biol<\/strong><\/span>.\u00a0 2026 Feb 1;74(2):177-191. doi: 10.1165\/rcmb.2025-0169OC. PMID: 40920963<\/span><\/span><\/span><\/p>\n

<\/div>\n<\/div>\n\n

2025<\/h3>
<\/p>\n

Age-dependent glioma progression and functional decline in a syngeneic murine model: Host vulnerabilities and opportunities for targeted intervention.<\/a><\/strong> Leblanc H, Buzharsky M, Varelas X, Binello E, Ramirez S. Neurooncol Adv.<\/strong><\/span> 2025 Oct 15;8(1):vdaf222. doi: 10.1093\/noajnl\/vdaf222. eCollection 2026 Jan-Dec. PMID: 41613043 <\/span><\/span><\/span><\/p>\n

Life-long functional regeneration of in vivo airway epithelium by the engraftment of airway basal stem cells<\/span>.<\/a><\/strong> Ma L, Thapa BR, Le Suer JA, Tilston-L\u00fcnel A, Herriges MJ, Wang F, Bawa PS, Varelas X, Hawkins FJ, Kotton DN. Nat Protoc<\/strong><\/span>. 2025 Mar;20(3):810-842. doi: 10.1038\/s41596-024-01067-y. PMID: 39501108 <\/span><\/span><\/span><\/p>\n

Protocol for the differentiation of human alveolar epithelial type I cells from pluripotent stem cell-derived type II-like cells.<\/a><\/strong><\/span> Burgess CL, Ayers LJ, Minakin K, Alysandratos KD, Varelas X, Kotton DN. STAR Protoc<\/strong><\/span>. 2025 Mar 5;6(1):103667. doi: 10.1016\/j.xpro.2025.103667. PMID: 40048418<\/span><\/span><\/span><\/p>\n

Reply to Huang et al.: Sowing Tailored Seeds: Gene-edited Basal Cells for Precision Regulation of Airway Phenotypes.<\/a><\/strong><\/span>
\nBerical AC, Kiyokawa H, Beermann ML, Wallman D, Cherfane G, Dunphy V, Pan J, Tilston-Lunel A, Varelas X, Horani A, Brody SL, Kotton DN, Hawkins FJ. Am J Respir Crit Care Med<\/strong><\/span>. 2025 Feb 25. doi: 10.1164\/rccm.202412-2535LE. PMID: 39999444 <\/span><\/span><\/span><\/p>\n

LATS1\/2 inactivation in the mammary epithelium drives the evolution of a tumor-associated niche.<\/a><\/strong><\/span>\u00a0Kern JG, Kroehling L, Spinella AJ, Monti S, Varelas X. EMBO Rep<\/strong><\/span>. 2025 Feb 14. doi: 10.1038\/s44319-025-00370-3. \u00a0PMID: 39953252<\/span><\/span><\/span><\/p>\n

YAP Deficiency Drives NF-\u03baB Hyperactivation to Disrupt Airway Epithelium Differentiation in Congenital Diaphragmatic Hernia.<\/a><\/strong> Aubert O, Amonkar GM, Varelas X, Tilston-Lunel A, Lerou PH, Zalieckas JM, Buchmiller TL, Varisco B, Marotta M, Peiro JL, Ai X. Am J Respir Cell Mol Biol<\/strong><\/span>.<\/strong> 2025 Jan;72(1):112-115. doi: 10.1165\/rcmb.2024-0270LE. PMID: 41378967<\/span><\/span><\/span><\/p>\n

<\/div>\n<\/div>\n\n

2024<\/h3>
<\/p>\n

Multiomic profiling of chronically activated CD4+ T cells identifies drivers of exhaustion and metabolic reprogramming.<\/a><\/strong><\/span> Lawton ML, Inge MM, Blum BC, Smith-Mahoney EL, Bolzan D, Lin W, McConney C, Porter J, Moore J, Youssef A, Tharani Y, Varelas X, Denis GV, Wong WW, Padhorny D, Kozakov D, Siggers T, Wuchty S, Snyder-Cappione J, Emili A. PLoS Biol.<\/strong><\/span> 2024 Dec 17;22(12):e3002943. doi: 10.1371\/journal.pbio.3002943.PMID: 39689157<\/span><\/span><\/span><\/p>\n

Fetal Tracheal Occlusion Corelates with Normalized YAP Expression and Alveolar Epithelial Differentiation in CDH.<\/a><\/strong><\/span>\u00a0 Aubert O, Miyake Y, Amonkar GM, Dinwoodie OM, Varisco BM, Marotta M, Zhao C, Wagner R, Chen YW, Moscatello A, Tiozzo C, Varelas X, Lerou PH, Peiro JL, Keijzer R, Ai X. Am J Respir Cell Mol Biol<\/strong><\/span>. 2024 Dec 11. doi: 10.1165\/rcmb.2024-0323OC. PMID: 39661950<\/span><\/span><\/span><\/p>\n

Airway Disease Modeling with Gene-edited Human Basal Cell Transplantation<\/span>.<\/a><\/strong> Berical AC, Kiyokawa H, Beermann ML, Wallman D, Cherfane G, Dunphy V, Pan J, Tilston-Lunel A, Varelas X, Horani A, Brody SL, Kotton DN, Hawkins FJ. Am J Respir Crit Care Med.<\/span>\u00a0<\/strong> 2024 Nov 8. doi: 10.1164\/rccm.202406-1110RL. PMID: 39514838<\/span><\/span><\/span><\/span><\/a><\/strong><\/span><\/span><\/span><\/p>\n

Influenza induces lung lymphangiogenesis independent of YAP\/TAZ activity in lymphatic endothelial<\/span> cells.<\/a><\/strong>\u00a0Crossey E, Carty S, Shao F, Henao-Vasquez J, Ysasi AB, Zeng M, Hinds A, Lo M, Tilston-Lunel A, Varelas X, Jones MR, Fine A. Sci Rep<\/strong><\/span>. 2024 Sep 12;14(1):21324. doi: 10.1038\/s41598-024-72115-6.
\nPMID: 39266641 <\/span><\/span><\/span><\/p>\n

Lung injury-induced activated endothelial cell states persist in aging-associated progressive fibrosis.<\/span><\/a> <\/strong>Raslan AA, Pham TX, Lee J, Kontodimas K, Tilston-Lunel A, Schmottlach J, Hong J, Dinc T, Bujor AM, Caporarello N, Thiriot A, von Andrian UH, Huang SK, Nicosia RF, Trojanowska M, Varelas X*, Ligresti G*. Nat Commun<\/strong><\/span>. 2024 Jun 27;15(1):5449. doi: 10.1038\/s41467-024-49545-x.
\nPMID: 38937456<\/span><\/span><\/span><\/p>\n

B cells in the pneumococcus-infected lung are heterogeneous and require CD4+ T cell help including CD40L to become resident memory B cells cells.<\/span><\/a> <\/strong>Etesami NS, Barker KA, Shenoy AT, De Ana CL, Arafa EI, Grifno GN, Matschulat AM, Vannini ME, Pihl RMF, Breen MP, Soucy AM, Goltry WN, Ha CT, Betsuyaku H, Browning JL, Varelas X, Traber KE, Jones MR, Quinton LJ, Maglione PJ, Nia HT, Belkina AC, Mizgerd JP. Front Immunol.<\/strong><\/span> 2024 Apr 23;15:1382638. doi: 10.3389\/fimmu.2024.1382638. eCollection 2024.
\nPMID: 38715601 <\/span><\/span><\/span><\/p>\n

Generation of human alveolar epithelial type I cells from pluripotent stem cells.<\/span><\/a> <\/strong>Burgess CL, Huang J, Bawa PS, Alysandratos KD, Minakin K, Ayers LJ, Morley MP, Babu A, Villacorta-Martin C, Yampolskaya M, Hinds A, Thapa BR, Wang F, Matschulat A, Mehta P, Morrisey EE, Varelas X, Kotton DN. Cell Stem Cell<\/strong><\/span>. 2024 Apr 15:S1934-5909(24)00098-5. doi: 10.1016\/j.stem.2024.03.017. PMID: 38642558<\/span><\/span><\/span><\/p>\n

<\/div>\n<\/div>\n\n

2023<\/h3>
<\/p>\n

Airway stem cell reconstitution by the transplantation of primary or pluripotent stem cell-derived basal cells<\/a>.<\/strong> Ma L, Thapa BR, Le Suer JA, Tilston-L\u00fcnel A, Herriges MJ, Berical A, Beermann ML, Wang F, Bawa PS, Kohn A, Ysasi AB, Kiyokawa H, Matte TM, Randell SH, Varelas X, Hawkins FJ, Kotton DN. Cell Stem Cell<\/strong><\/span>.<\/strong> 2023 Sep 7;30(9):1199-1216.e7. doi: 10.1016\/j.stem.2023.07.014. Epub 2023 Aug 24. PMID: 37625411\u00a0<\/span><\/span><\/span><\/p>\n

Total RNA sequencing reveals gene expression and microbial alterations shared by oral pre-malignant lesions and cancer. <\/a> <\/strong>Khan MM, Frustino J, Villa A, Nguyen BC, Woo SB, Johnson WE, Varelas X, Kukuruzinska M, Monti S. Hum Genomics<\/span>.<\/strong> 2023 Aug 4;17(1):72. doi: 10.1186\/s40246-023-00519-y. PMID: 37542347<\/span><\/span><\/span><\/p>\n

\u03b2-catenin\/CBP activation of mTORC1 signaling promotes partial epithelial-mesenchymal states in head and neck cancer. <\/a> <\/strong>Reed ER, Jankowski SA, Spinella AJ, Noonan V, Haddad R, Nomoto K, Matsui J, Bais MV, Varelas X, Kukuruzinska MA, Monti S. Transl Res<\/span>.<\/strong> 2023 Oct;260:46-60. doi: 10.1016\/j.trsl.2023.05.007. Epub 2023 Jun 21. PMID: 37353110 <\/span><\/span><\/span><\/p>\n

Structure learning for gene regulatory networks.<\/a>\u00a0 <\/strong>Federico A, Kern J, Varelas X, Monti S. PLoS Comput Biol<\/span>.<\/strong> 2023 May 18;19(5):e1011118. doi: 10.1371\/journal.pcbi.1011118. eCollection 2023 May. PMID: 37200395<\/span><\/span><\/span><\/p>\n

Convergence of YAP\/TAZ, TEAD and TP63 activity is associated with bronchial premalignant severity and progression.<\/a>\u00a0 <\/strong>Ning B, Tilston-Lunel AM, Simonetti J, Hicks-Berthet J, Matschulat A, Pfefferkorn R, Spira A, Edwards M, Mazzilli S, Lenburg ME, Beane JE, Varelas X*. J Exp Clin Cancer Res<\/span>.<\/strong> 2023 May 8;42(1):116. doi: 10.1186\/s13046-023-02674-5. PMID: 37150829<\/span><\/span><\/span><\/p>\n

Polarity in respiratory development, homeostasis and disease.<\/a>\u00a0 <\/strong>Tilston-Lunel AM, Varelas X*. Curr Top Dev Biol<\/span>.<\/strong> 2023;154:285-315. doi: 10.1016\/bs.ctdb.2023.02.004. Epub 2023 Mar 15. PMID: 37100521<\/span><\/span><\/span><\/p>\n

<\/div>\n<\/div>\n\n

2022<\/h3>
<\/p>\n

Inactivation of LATS1\/2 drives luminal-basal plasticity to initiate basal-like mammary carcinomas.<\/a> <\/strong>Kern JG, Tilston-Lunel AM, Federico A, Ning B, Mueller A, Peppler GB, Stampouloglou E, Cheng N, Johnson RL, Lenburg ME, Beane JE, Monti S, <\/span>Varelas X*. <\/b>Nat Commun<\/span>.<\/strong> 2022 Nov 28;13(1):7198. doi: 10.1038\/s41467-022-34864-8.\u00a0<\/span>PMID: 36443313<\/span><\/span><\/p>\n

Virtual screening for small-molecule pathway regulators by image-profile matching.<\/a> <\/strong>Rohban MH, Fuller AM, Tan C, Goldstein JT, Syangtan D, Gutnick A, DeVine A, Nijsure MP, Rigby M, Sacher JR, Corsello SM, Peppler GB, Bogaczynska M, Boghossian A, Ciotti GE, Hands AT, Mekareeya A, Doan M, Gale JP, Derynck R, Turbyville T, Boerckel JD, Singh S, Kiessling LL, Schwarz TL, Varelas X, Wagner FF, Kafri R, Eisinger-Mathason TSK, Carpenter AE. Cell Syst<\/span>.<\/strong> 2022 Sep 21;13(9):724-736.e9. doi: 10.1016\/j.cels.2022.08.003. Epub 2022 Sep 2. PMID: 36057257 <\/span><\/span><\/p>\n

Basal extrusion of single-oncogenic mutant cells induces dome-like structures with altered microenvironments.<\/a> <\/strong>Shirai T, Sekai M, Kozawa K, Sato N, Tanimura N, Kon S, Matsumoto T, Murakami T, Ito S, Tilston-Lunel A, Varelas X, Fujita Y.\u00a0Cancer Sci<\/span>.<\/strong> 2022 Nov;113(11):3710-3721. doi: 10.1111\/cas.15483. Epub 2022 Aug 30.\u00a0PMID: 35816400\u00a0<\/span><\/span><\/p>\n

Verteporfin protects against Th17 cell-mediated EAE independently of YAP inhibition.<\/a> <\/strong>Brosinsky P, Leister H, Cheng N, Varelas X, Visekruna A, Luu M.\u00a0Eur J Immunol<\/span>.<\/strong> 2022 Sep;52(9):1523-1526. doi: 10.1002\/eji.202149564. Epub 2022 Jul 25.\u00a0PMID: 35776890<\/span><\/span><\/p>\n

Inactivation of the Hippo tumor suppressor pathway promotes melanoma.<\/a> <\/strong>Vittoria MA, Kingston N, Kotynkova K, Xia E, Hong R, Huang L, McDonald S, Tilston-Lunel A, Darp R, Campbell JD, Lang D, Xu X, Ceol CJ, Varelas X, Ganem NJ.\u00a0Nat Commun<\/span>.<\/strong> 2022 Jun 29;13(1):3732. doi: 10.1038\/s41467-022-31399-w.\u00a0PMID: 35768444<\/span><\/span><\/p>\n

Obesity-induced senescent macrophages activate a fibrotic transcriptional program in adipocyte progenitors.<\/a> <\/strong>Rabhi N, Desevin K, Belkina AC, Tilston-Lunel A, Varelas X, Layne MD, Farmer SR.\u00a0Life Sci Alliance<\/span>.<\/strong> 2022 Feb 18;5(5):e202101286. doi: 10.26508\/lsa.202101286. Print 2022 May.\u00a0PMID: 35181634<\/p>\n

Epithelial LIF signaling limits apoptosis and lung injury during bacterial pneumonia.<\/a>\u00a0<\/strong>Na E, Allen E, Baird LA, Odom CV, Korkmaz FT, Shenoy AT, Matschulat AM, Jones MR, Kotton DN, Mizgerd JP, Varelas X, Traber KE, Quinton LJ.\u00a0Am J Physiol Lung Cell Mol Physiol<\/span>.<\/strong> 2022 Feb 9. doi: 10.1152\/ajplung.00325.2021. Online ahead of print.\u00a0PMID: 35137631<\/p>\n

Inhibition of LSD1 attenuates oral cancer development and promotes therapeutic efficacy of immune checkpoint blockade and Yap\/Taz inhibition.<\/a>\u00a0<\/strong>Alhousami T, Diny M, Ali F, Shin J, Kumar G, Kumar V, Campbell J, Noonan V, Hanna G, Denis GV, Monti S, Kukuruzinska MA, Varelas X, Bais MV.\u00a0Mol Cancer Res<\/span>.<\/strong> 2022 Feb 1:molcanres.0310.2021. doi: 10.1158\/1541-7786.MCR-21-0310. Online ahead of print.\u00a0PMID: 35105672<\/p>\n

<\/div>\n<\/div>\n\n

2021<\/h3>
<\/p>\n

The Hsp70-Bag3 complex modulates the phosphorylation and nuclear translocation of Hippo pathway protein Yap.<\/a>\u00a0<\/strong>Baldan S, Meriin AB, Yaglom J, Alexandrov I, Varelas X, Xiao ZJ, Sherman MY.
\nJ Cell Sci<\/strong><\/span>.<\/strong> 2021 Dec 1;134(23):jcs259107. doi: 10.1242\/jcs.259107. Epub 2021 Dec 2.\u00a0PMID: 34761265<\/p>\n

Patient-specific iPSCs carrying an SFTPC mutation reveal the intrinsic alveolar epithelial dysfunction at the inception of interstitial lung disease<\/a>.\u00a0<\/strong>Alysandratos KD, Russo SJ, Petcherski A, Taddeo EP, Ac\u00edn-P\u00e9rez R, Villacorta-Martin C, Jean JC, Mulugeta S, Rodriguez LR, Blum BC, Hekman RM, Hix OT, Minakin K, Vedaie M, Kook S, Tilston-Lunel AM, Varelas X, Wambach JA, Cole FS, Hamvas A, Young LR, Liesa M, Emili A, Guttentag SH, Shirihai OS, Beers MF, Kotton DN.\u00a0Cell Rep<\/span>.<\/strong> 2021 Aug 31;36(9):109636. doi: 10.1016\/j.celrep.2021.109636.\u00a0PMID: 34469722<\/p>\n

Yap\/Taz inhibit goblet cell fate to maintain lung epithelial homeostasis<\/a>.<\/strong> Hicks-Berthet J, Ning B, Federico A, Tilston-Lunel A, Matschulat A, Ai X, Lenburg ME, Beane J, Monti S, Varelas X*.\u00a0Cell Rep<\/strong><\/span>.<\/strong> 2021 Jul 13;36(2):109347. doi: 10.1016\/j.celrep.2021.109347.\u00a0PMID: 34260916<\/p>\n

Gene expression alterations in salivary gland epithelia of Sj\u00f6gren’s syndrome patients are associated with clinical and histopathological manifestations<\/a>.<\/strong> Dela Cruz A*, Kartha V*, Tilston-Lunel A*, Mi R, Reynolds TL, Mingueneau M, Monti S, Jensen JL, Skarstein K, Varelas X*, Kukuruzinska MA*. Sci Rep<\/span>. <\/strong>2021 May 27;11(1):11154. doi: 10.1038\/s41598-021-90569-w.\u00a0PMID: 34045583<\/p>\n

Aberrant epithelial polarity cues drive the development of precancerous airway lesions<\/a>.\u00a0<\/strong>Tilston-Lunel A, Mazzilli S, Kingston NM, Szymaniak AD, Hicks-Berthet J, Kern JG, Abo K, Reid ME, Perdomo C, Wilson AA, Spira A, Beane J, Varelas X*.\u00a0Proc Natl Acad Sci U S A<\/span>.<\/strong> 2021 May 4;118(18):e2019282118. doi: 10.1073\/pnas.2019282118.\u00a0PMID: 33903236<\/p>\n

ZNF416 is a pivotal transcriptional regulator of fibroblast mechanoactivation<\/a>.\u00a0<\/strong>Jones DL, Meridew JA, Link PA, Ducharme MT, Lydon KL, Choi KM, Caporarello N, Tan Q, Diaz Espinosa AM, Xiong Y, Lee JH, Ye Z, Yan H, Ordog T, Ligresti G, Varelas X, Tschumperlin DJ.\u00a0J Cell Biol<\/span>.<\/strong> 2021 May 3;220(5):e202007152. doi: 10.1083\/jcb.202007152.\u00a0PMID: 33625469<\/p>\n

Loss of G-Protein Pathway Suppressor 2 Promotes Tumor Growth Through Activation of AKT Signaling<\/a>.\u00a0<\/strong>Chan S, Smith E, Gao Y, Kwan J, Blum BC, Tilston-Lunel AM, Turcinovic I, Varelas X, Cardamone MD, Monti S, Emili A, Perissi V.\u00a0Front Cell Dev Biol.<\/span><\/strong> 2021 Jan 7;8:608044. doi: 10.3389\/fcell.2020.608044. eCollection 2020.\u00a0PMID: 33490071<\/p>\n

Actionable Cytopathogenic Host Responses of Human Alveolar Type 2 Cells to SARS-CoV-2<\/a>.\u00a0<\/strong>Hekman RM, Hume AJ, Goel RK, Abo KM, Huang J, Blum BC, Werder RB, Suder EL, Paul I, Phanse S, Youssef A, Alysandratos KD, Padhorny D, Ojha S, Mora-Martin A, Kretov D, Ash PEA, Verma M, Zhao J, Patten JJ, Villacorta-Martin C, Bolzan D, Perea-Resa C, Bullitt E, Hinds A, Tilston-Lunel A, Varelas X, Farhangmehr S, Braunschweig U, Kwan JH, McComb M, Basu A, Saeed M, Perissi V, Burks EJ, Layne MD, Connor JH, Davey R, Cheng JX, Wolozin BL, Blencowe BJ, Wuchty S, Lyons SM, Kozakov D, Cifuentes D, Blower M, Kotton DN, Wilson AA, M\u00fchlberger E, Emili A.\u00a0Mol Cell<\/span>.<\/strong> 2021 Jan 7;81(1):212. doi: 10.1016\/j.molcel.2020.12.028.\u00a0PMID: 33417854<\/p>\n

<\/div>\n<\/div>\n\n

2020<\/h3>
<\/p>\n

Naturally occurring hotspot cancer mutations in G\u03b113 promote oncogenic signaling<\/a>.\u00a0<\/strong>Maziarz M, Federico A, Zhao J, Dujmusic L, Zhao Z, Monti S, Varelas X, Garcia-Marcos M.\u00a0J Biol Chem<\/span>.<\/strong> 2020 Dec 4;295(49):16897-16904. doi: 10.1074\/jbc.AC120.014698. Epub 2020 Oct 27.\u00a0PMID: 33109615<\/p>\n

Lung Atelectasis Promotes Immune and Barrier Dysfunction as Revealed by Transcriptome Sequencing in Female Sheep.<\/strong><\/a>\u00a0Zeng C, Motta-Ribeiro GC, Hinoshita T, Lessa MA, Winkler T, Grogg K, Kingston NM, Hutchinson JN, Sholl LM, Fang X, Varelas X, Layne MD, Baron RM, Vidal Melo MF.\u00a0Anesthesiology<\/span>.<\/strong> 2020 Nov 1;133(5):1060-1076. doi: 10.1097\/ALN.0000000000003491.\u00a0PMID: 32796202<\/p>\n

The Tumor Suppressor CYLD Inhibits Mammary Epithelial to Mesenchymal Transition by the Coordinated Inhibition of YAP\/TAZ and TGFbeta Signaling.<\/strong><\/a>\u00a0Pseftogas A, Xanthopoulos K, Poutahidis T, Ainali C, Dafou D, Panteris E, Kern JG, Varelas X, Hardas A, Gonidas C, Tsingotjidou A, Hatzivassiliou E, Mosialos G.\u00a0Cancers (Basel)<\/span>.<\/strong> 2020 Jul 24;12(8):2047. doi: 10.3390\/cancers12082047.\u00a0PMID: 32722292<\/p>\n

<\/a>Targeting the Hippo pathway in cancer, fibrosis, wound healing and regenerative medicine.<\/a>\u00a0<\/strong>Dey A, Varelas X, Guan KL.\u00a0Nat Rev Drug Discov.<\/span> <\/strong>2020 Jul;19(7):480-494. doi: 10.1038\/s41573-020-0070-z. Epub 2020 Jun 17.\u00a0PMID: 32555376<\/p>\n

The in vivo genetic program of murine primordial lung epithelial progenitors.<\/strong><\/a>\u00a0Ikonomou L, Herriges MJ, Lewandowski SL, Marsland R 3rd, Villacorta-Martin C, Caballero IS, Frank DB, Sanghrajka RM, Dame K, Ka\u0144du\u0142a MM, Hicks-Berthet J, Lawton ML, Christodoulou C, Fabian AJ, Kolaczyk E, Varelas X, Morrisey EE, Shannon JM, Mehta P, Kotton DN.\u00a0Nat Commun<\/strong><\/span>.<\/strong>2020 Jan 31;11(1):635. doi: 10.1038\/s41467-020-14348-3.\u00a0PMID: 32005814<\/p>\n

Yap suppresses T-cell function and infiltration in the tumor microenvironment.<\/a>\u00a0<\/strong>Stampouloglou E, Cheng N, Federico A, Slaby E, Monti S, Szeto GL*, Varelas X*. PLoS Biol<\/span>.<\/strong> 2020 Jan 13;18(1):e3000591. doi: 10.1371\/journal.pbio.3000591. eCollection 2020 Jan.\u00a0PMID: 31929526<\/p>\n

<\/div>\n<\/div>\n\n

2019<\/h3>
<\/p>\n

Identification of candidate cancer drivers by integrative Epi-DNA and Gene Expression (iEDGE) data analysis.<\/strong><\/a>\u00a0Li A, Chapuy B, Varelas X, Sebastiani P, Monti S.\u00a0Sci Rep<\/strong><\/span>.<\/strong>2019 Nov 15;9(1):16904. doi: 10.1038\/s41598-019-52886-z.\u00a0PMID: 31729402<\/p>\n

Selective YAP\/TAZ inhibition in fibroblasts via dopamine receptor D1 agonism reverses fibrosis.<\/a>\u00a0<\/strong>Haak AJ, Kostallari E, Sicard D, Ligresti G, Choi KM, Caporarello N, Jones DL, Tan Q, Meridew J, Diaz Espinosa AM, Aravamudhan A, Maiers JL, Britt RD Jr, Roden AC, Pabelick CM, Prakash YS, Nouraie SM, Li X, Zhang Y, Kass DJ, Lagares D, Tager AM, Varelas X, Shah VH, Tschumperlin DJ.\u00a0Sci Transl Med<\/span>.<\/strong> 2019 Oct 30;11(516):eaau6296. doi: 10.1126\/scitranslmed.aau6296.\u00a0PMID: 31666402<\/p>\n

TGFbeta-induced fibroblast activation requires persistent and targeted HDAC-mediated gene repression.<\/strong><\/a>\u00a0Jones DL, Haak AJ, Caporarello N, Choi KM, Ye Z, Yan H, Varelas X, Ordog T, Ligresti G, Tschumperlin DJ.\u00a0J Cell Sci<\/span>. <\/strong>2019 Oct 18;132(20):jcs233486. doi: 10.1242\/jcs.233486.\u00a0PMID: 31527052<\/p>\n

TAZ Forces Lateral Inhibition.<\/a>\u00a0<\/strong>Kern JG, Varelas X*. Dev Cell<\/span>. <\/strong>2019 Mar 25;48(6):748-750. doi: 10.1016\/j.devcel.2019.03.006.
\nPMID: 30913406<\/p>\n

CaDrA: A Computational Framework for Performing Candidate Driver Analyses Using Genomic Features.<\/a>\u00a0<\/strong>Kartha VK, Sebastiani P, Kern JG, Zhang L, Varelas X, Monti S.\u00a0Front Genet<\/span>.<\/strong> 2019 Feb 19;10:121. doi: 10.3389\/fgene.2019.00121. eCollection 2019.\u00a0PMID: 30838036<\/p>\n

Immunofluorescence Microscopy to Study Endogenous TAZ in Mammalian Cells.<\/a>\u00a0<\/strong>Kingston NM, Tilston-Lunel AM, Hicks-Berthet J, Varelas X*. Methods Mol Biol<\/span>.<\/strong> 2019;1893:107-113. doi: 10.1007\/978-1-4939-8910-2_9.\u00a0PMID: 30565129<\/p>\n

<\/div>\n<\/div>\n\n

2018<\/h3>
<\/p>\n

Phosphatidic Acid Signals via the Hippo Pathway.<\/a>\u00a0<\/strong>Stampouloglou E, Varelas X*. Mol Cell<\/span>. <\/strong>2018 Oct 18;72(2):205-206. doi: 10.1016\/j.molcel.2018.10.004.\u00a0PMID: 30340020<\/p>\n

Functional and genomic analyses reveal therapeutic potential of targeting \u03b2-catenin\/CBP activity in head and neck cancer.<\/strong><\/a>\u00a0Kartha VK, Alamoud KA, Sadykov K, Nguyen BC, Laroche F, Feng H, Lee J, Pai SI, Varelas X, Egloff AM, Snyder-Cappione JE, Belkina AC, Bais MV, Monti S, Kukuruzinska MA.\u00a0Genome Med<\/span>.<\/strong> 2018 Jul 20;10(1):54. doi: 10.1186\/s13073-018-0569-7.\u00a0PMID: 30029671<\/p>\n

Hsp70-Bag3 complex is a hub for proteotoxicity-induced signaling that controls protein aggregation.<\/strong><\/a>\u00a0Meriin AB, Narayanan A, Meng L, Alexandrov I, Varelas X, Ciss\u00e9 II, Sherman MY.\u00a0Proc Natl Acad Sci U S A<\/strong><\/span>. <\/strong>2018 Jul 24;115(30):E7043-E7052. doi: 10.1073\/pnas.1803130115. Epub 2018 Jul 9.\u00a0PMID: 29987014<\/p>\n

Glutamine-utilizing transaminases are a metabolic vulnerability of TAZ\/YAP-activated cancer cells.<\/a>\u00a0<\/strong>Yang CS, Stampouloglou E, Kingston NM, Zhang L, Monti S, Varelas X*. EMBO Rep<\/span>. <\/strong>2018 Jun;19(6):e43577. doi: 10.15252\/embr.201643577. Epub 2018 Apr 16.\u00a0PMID: 29661856<\/p>\n

<\/div>\n<\/div>\n\n

2017<\/h3>
<\/p>\n

Therapeutic Targeting of TAZ and YAP by Dimethyl Fumarate in Systemic Sclerosis Fibrosis.<\/strong><\/a>\u00a0Toyama T, Looney AP, Baker BM, Stawski L, Haines P, Simms R, Szymaniak AD, Varelas X, Trojanowska M.\u00a0J Invest Dermatol<\/span>. 2018 Jan;138(1):78-88. doi: 10.1016\/j.jid.2017.08.024. Epub 2017 Sep 1.\u00a0PMID: 28870693<\/p>\n

Targeted apoptosis of myofibroblasts with the BH3 mimetic ABT-263 reverses established fibrosis.<\/a>\u00a0<\/strong>Lagares D, Santos A, Grasberger PE, Liu F, Probst CK, Rahimi RA, Sakai N, Kuehl T, Ryan J, Bhola P, Montero J, Kapoor M, Baron M, Varelas X, Tschumperlin DJ, Letai A, Tager AM.\u00a0Sci Transl Med<\/span>. 2017 Dec 13;9(420):eaal3765. doi: 10.1126\/scitranslmed.aal3765.\u00a0PMID: 29237758<\/p>\n

Inhibition of LSD1 epigenetically attenuates oral cancer growth and metastasis.<\/a>\u00a0<\/strong>Alsaqer SF, Tashkandi MM, Kartha VK, Yang YT, Alkheriji Y, Salama A, Varelas X, Kukuruzinska M, Monti S, Bais MV.\u00a0Oncotarget. <\/span>2017 Jul 27;8(43):73372-73386. doi: 10.18632\/oncotarget.19637. eCollection 2017 Sep 26.\u00a0PMID: 29088714.<\/p>\n

Expression of Piwi protein MIWI2 defines a distinct population of multiciliated cells.<\/a>\u00a0<\/strong>Wasserman GA, Szymaniak AD, Hinds AC, Yamamoto K, Kamata H, Smith NM, Hilliard KL, Carrieri C, Labadorf AT, Quinton LJ, Ai X, Varelas X, Chen F, Mizgerd JP, Fine A, O’Carroll D, Jones MR.\u00a0J Clin Invest<\/span>. 2017 Oct 2;127(10):3866-3876. doi: 10.1172\/JCI94639. Epub 2017 Sep 18.\u00a0PMID: 28920925<\/p>\n

Integrin-FAK-CDC42-PP1A signaling gnaws at YAP\/TAZ activity to control incisor stem cells.<\/strong><\/a> Hicks-Berthet J, Varelas X*.\u00a0Bioessays<\/span>. 2017 Oct;39(10):10.1002\/bies.201700116. doi: 10.1002\/bies.201700116. Epub 2017 Sep 11.\u00a0PMID: 28891248<\/p>\n

Arterial stiffness induces remodeling phenotypes in pulmonary artery smooth muscle cells via YAP\/TAZ-mediated repression of cyclooxygenase-2.<\/a>\u00a0<\/strong>Dieffenbach PB, Haeger CM, Coronata AMF, Choi KM, Varelas X, Tschumperlin DJ, Fredenburgh LE.\u00a0Am J Physiol Lung Cell Mol Physiol<\/span>. 2017 Sep 1;313(3):L628-L647. doi: 10.1152\/ajplung.00173.2017. Epub 2017 Jun 22.\u00a0PMID: 28642262<\/p>\n

The Hippo pathway effector YAP is an essential regulator of ductal progenitor patterning in the mouse submandibular gland.<\/a>\u00a0<\/strong>Szymaniak AD, Mi R, McCarthy SE, Gower AC, Reynolds TL, Mingueneau M, Kukuruzinska M, Varelas X*. Elife<\/span>. 2017 May 11;6:e23499. doi: 10.7554\/eLife.23499.\u00a0PMID: 28492365<\/p>\n

Systematic morphological profiling of human gene and allele function via Cell Painting.<\/a>\u00a0<\/strong>Rohban MH, Singh S, Wu X, Berthet JB, Bray MA, Shrestha Y, Varelas X, Boehm JS, Carpenter AE.\u00a0Elife<\/span>. 2017 Mar 18;6:e24060. doi: 10.7554\/eLife.24060.\u00a0PMID: 28315521<\/p>\n

TAZ activation drives fibroblast spheroid growth, expression of profibrotic paracrine signals, and context-dependent ECM gene expression.<\/a>\u00a0<\/strong>Jorgenson AJ, Choi KM, Sicard D, Smith KM, Hiemer SE, Varelas X, Tschumperlin DJ.\u00a0Am J Physiol Cell Physiol<\/span>. 2017 Mar 1;312(3):C277-C285. doi: 10.1152\/ajpcell.00205.2016. Epub 2016 Nov 23.\u00a0PMID: 27881410 Free PMC article.<\/p>\n

<\/div>\n<\/div>\n\n

2016<\/h3>
<\/p>\n

Altered RNA editing in 3′ UTR perturbs microRNA-mediated regulation of oncogenes and tumor-suppressors.<\/a>\u00a0<\/strong>Zhang L, Yang CS, Varelas X, Monti S.\u00a0Sci Rep.<\/span> 2016 Mar 16;6:23226. doi: 10.1038\/srep23226.\u00a0PMID: 26980570 Free PMC article.<\/p>\n

<\/div>\n<\/div>\n\n

2015<\/h3>
<\/p>\n

Crumbs3-Mediated Polarity Directs Airway Epithelial Cell Fate through the Hippo Pathway Effector Yap.<\/a>\u00a0<\/strong>Szymaniak AD, Mahoney JE, Cardoso WV, Varelas X*. Dev Cell<\/span>. 2015 Aug 10;34(3):283-96. doi: 10.1016\/j.devcel.2015.06.020. Epub 2015 Jul 30.\u00a0PMID: 26235047 Free PMC article.<\/p>\n

A YAP\/TAZ-Regulated Molecular Signature Is Associated with Oral Squamous Cell Carcinoma.<\/strong><\/a> Hiemer SE, Zhang L, Kartha VK, Packer TS, Almershed M, Noonan V, Kukuruzinska M, Bais MV, Monti S, Varelas X*.\u00a0Mol Cancer Res<\/span>. 2015 Jun;13(6):957-68. doi: 10.1158\/1541-7786.MCR-14-0580. Epub 2015 Mar 20.\u00a0PMID: 25794680<\/p>\n

Distinct polarity cues direct Taz\/Yap and TGF\u03b2 receptor localization to differentially control TGF\u03b2-induced Smad signaling.\u00a0<\/strong><\/a>Narimatsu M, Samavarchi-Tehrani P, Varelas X*, Wrana JL*.\u00a0Dev Cell.<\/span> 2015 Mar 9;32(5):652-6. doi: 10.1016\/j.devcel.2015.02.019.\u00a0PMID: 25758863 Free article.<\/p>\n

Notch3-Jagged signaling controls the pool of undifferentiated airway progenitors.\u00a0<\/strong><\/a>Mori M, Mahoney JE, Stupnikov MR, Paez-Cortez JR, Szymaniak AD, Varelas X, Herrick DB, Schwob J, Zhang H, Cardoso WV.\u00a0Development.<\/span> 2015 Jan 15;142(2):258-67. doi: 10.1242\/dev.116855.\u00a0PMID: 25564622<\/p>\n

Mechanosignaling through YAP and TAZ drives fibroblast activation and fibrosis.<\/strong>\u00a0<\/a>Liu F, Lagares D, Choi KM, Stopfer L, Marinkovi\u0107 A, Vrbanac V, Probst CK, Hiemer SE, Sisson TH, Horowitz JC, Rosas IO, Fredenburgh LE, Feghali-Bostwick C, Varelas X, Tager AM, Tschumperlin DJ.\u00a0Am J Physiol Lung Cell Mol Physiol<\/span>. 2015 Feb 15;308(4):L344-57. doi: 10.1152\/ajplung.00300.2014. Epub 2014 Dec 12.\u00a0PMID: 25502501<\/p>\n

<\/div>\n<\/div>\n\n

2014<\/h3>
<\/p>\n

Head and neck cancer: from research to therapy and cure.<\/a>\u00a0<\/strong>Varelas X, Kukuruzinska MA.\u00a0Ann N Y Acad Sci<\/span>. 2014 Dec;1333:1-32. doi: 10.1111\/nyas.12613.\u00a0PMID: 25532687<\/p>\n

The hippo pathway effector Yap controls patterning and differentiation of airway epithelial progenitors. <\/strong><\/a>Mahoney JE, Mori M, Szymaniak AD, Varelas X, Cardoso WV.\u00a0Dev Cell.<\/span> 2014 Jul 28;30(2):137-50. doi: 10.1016\/j.devcel.2014.06.003. Epub 2014 Jul 17.\u00a0PMID: 25043473<\/p>\n

Protein N-glycosylation in oral cancer: dysregulated cellular networks among DPAGT1, E-cadherin adhesion and canonical Wnt signaling.<\/a>\u00a0<\/strong>Varelas X, Bouchie MP, Kukuruzinska MA.\u00a0Glycobiology<\/span>. 2014 Jul;24(7):579-91. doi: 10.1093\/glycob\/cwu031. Epub 2014 Apr 17.\u00a0PMID: 24742667<\/p>\n

The Hippo pathway effectors TAZ and YAP in development, homeostasis and disease.<\/a>\u00a0<\/strong>Varelas X*. Development<\/span>. 2014 Apr;141(8):1614-26. doi: 10.1242\/dev.102376.\u00a0PMID: 24715453<\/p>\n

The transcriptional regulators TAZ and YAP direct transforming growth factor \u03b2-induced tumorigenic phenotypes in breast cancer cells<\/strong><\/a>. <\/strong>Hiemer SE, Szymaniak AD, Varelas X*. J Biol Chem<\/span>. 2014 May 9;289(19):13461-74. doi: 10.1074\/jbc.M113.529115. Epub 2014 Mar 19.\u00a0PMID: 24648515<\/p>\n

<\/div>\n<\/div>\n\n

2013<\/h3>
<\/p>\n

Switch enhancers interpret TGF-\u03b2 and Hippo signaling to control cell fate in human embryonic stem cells.<\/a>\u00a0<\/strong>Beyer TA, Weiss A, Khomchuk Y, Huang K, Ogunjimi AA, Varelas X, Wrana JL.\u00a0Cell Rep<\/span>. 2013 Dec 26;5(6):1611-24. doi: 10.1016\/j.celrep.2013.11.021. Epub 2013 Dec 12.\u00a0PMID: 24332857<\/p>\n

The Hippo pathway effectors TAZ\/YAP regulate dicer expression and microRNA biogenesis through Let-7.<\/a>\u00a0<\/strong>Chaulk SG, Lattanzi VJ, Hiemer SE, Fahlman RP*, Varelas X*. J Biol Chem<\/span>. 2014 Jan 24;289(4):1886-91. doi: 10.1074\/jbc.C113.529362. Epub 2013 Dec 9.\u00a0PMID: 24324261<\/p>\n

The Hippo signaling pathway is required for salivary gland development and its dysregulation is associated with Sjogren’s syndrome.<\/a>\u00a0<\/strong>Enger TB, Samad-Zadeh A, Bouchie MP, Skarstein K, Galtung HK, Mera T, Walker J, Menko AS, Varelas X, Faustman DL, Jensen JL, Kukuruzinska MA.\u00a0Lab Invest<\/span>. 2013 Nov;93(11):1203-18. doi: 10.1038\/labinvest.2013.114. Epub 2013 Sep 30.
\nPMID: 24080911<\/p>\n

N-glycosylation induces the CTHRC1 protein and drives oral cancer cell migration.<\/a>\u00a0<\/strong>Liu G, Sengupta PK, Jamal B, Yang HY, Bouchie MP, Lindner V, Varelas X, Kukuruzinska MA.\u00a0J Biol Chem<\/span>. 2013 Jul 12;288(28):20217-27. doi: 10.1074\/jbc.M113.473785. Epub 2013 May 23.\u00a0PMID: 23703614<\/p>\n

Stem cell regulation by the Hippo pathway.<\/strong><\/a> Hiemer SE, Varelas X*. Biochim Biophys Acta<\/span>. 2013 Feb;1830(2):2323-34. doi: 10.1016\/j.bbagen.2012.07.005. Epub 2012 Jul 20.\u00a0PMID: 22824335<\/p>\n

<\/div>\n<\/div>\n\n

2012<\/h3>
<\/p>\n

Coordinating developmental signaling: novel roles for the Hippo pathway.<\/a>\u00a0<\/strong>Varelas X*, Wrana JL*. Trends Cell Biol.<\/span> 2012 Feb;22(2):88-96. doi: 10.1016\/j.tcb.2011.10.002. Epub 2011 Dec 5.\u00a0PMID: 22153608<\/p>\n

Integrating developmental signals: a Hippo in the (path)way.<\/a>\u00a0<\/strong>Mauviel A*, Nallet-Staub F, Varelas X*. Oncogene<\/span>. 2012 Apr 5;31(14):1743-56. doi: 10.1038\/onc.2011.363. Epub 2011 Aug 29.\u00a0PMID: 21874053<\/p>\n

<\/div>\n<\/div>\n\n

2011&before<\/h3>
<\/p>\n

An allosteric inhibitor of the human Cdc34 ubiquitin-conjugating enzyme.<\/a><\/strong> Ceccarelli DF, Tang X, Pelletier B, Orlicky S, Xie W, Plantevin V, Neculai D, Chou YC, Ogunjimi A, Al-Hakim A, Varelas X, Koszela J, Wasney GA, Vedadi M, Dhe-Paganon S, Cox S, Xu S, Lopez-Girona A, Mercurio F, Wrana J, Durocher D, Meloche S, Webb DR, Tyers M, Sicheri F. Cell. 2011 Jun 24;145(7):1075-87. doi: 10.1016\/j.cell.2011.05.039. Epub 2011 Jun 16. PMID: 21683433<\/span><\/span><\/span><\/p>\n

The Crumbs complex couples cell density sensing to Hippo-dependent control of the TGF-\u03b2-SMAD pathway.<\/a><\/strong> Varelas X, Samavarchi-Tehrani P, Narimatsu M, Weiss A, Cockburn K, Larsen BG, Rossant J, Wrana JL.\u00a0Dev Cell<\/span>. 2010 Dec 14;19(6):831-44. doi: 10.1016\/j.devcel.2010.11.012.\u00a0PMID: 21145499<\/span><\/span><\/span><\/p>\n

The Hippo pathway regulates Wnt\/beta-catenin signaling<\/span>.<\/a><\/strong> <\/strong>Varelas X, Miller BW, Sopko R, Song S, Gregorieff A, Fellouse FA, Sakuma R, Pawson T, Hunziker W, McNeill H, Wrana JL, Attisano L.\u00a0Dev Cell<\/span>. 2010 Apr 20;18(4):579-91. doi: 10.1016\/j.devcel.2010.03.007.\u00a0PMID: 20412773<\/span><\/span><\/span><\/p>\n

The ubiquitin binding region of the Smurf HECT domain facilitates polyubiquitylation and binding of ubiquitylated substrates. <\/a><\/strong>Ogunjimi AA, Wiesner S, Briant DJ, Varelas X, Sicheri F, Forman-Kay J, Wrana JL. J Biol Chem<\/span>. 2010 Feb 26;285(9):6308-15. doi: 10.1074\/jbc.M109.044537. Epub 2009 Dec 21. PMID: 20026602<\/span><\/span><\/span><\/p>\n

Phosphorylation of the tumor suppressor fat is regulated by its ligand Dachsous and the kinase discs overgrown.<\/a><\/strong> Sopko R, Silva E, Clayton L, Gardano L, Barrios-Rodiles M, Wrana J, Varelas X, Arbouzova NI, Shaw S, Saburi S, Matakatsu H, Blair S, McNeill H.\u00a0Curr Biol<\/strong>.<\/span> 2009 Jul 14;19(13):1112-7. doi: 10.1016\/j.cub.2009.05.049. Epub 2009 Jun 18.\u00a0PMID: 19540118<\/span><\/span><\/span><\/p>\n

TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal<\/span>.<\/a><\/strong> Varelas X, Sakuma R, Samavarchi-Tehrani P, Peerani R, Rao BM, Dembowy J, Yaffe MB, Zandstra PW, Wrana JL.\u00a0Nat Cell Biol.<\/strong><\/span> 2008 Jul;10(7):837-48. doi: 10.1038\/ncb1748. Epub 2008 Jun 22.\u00a0PMID: 18568018<\/span><\/span><\/span><\/p>\n

<\/div>\n<\/div>\n\n

 <\/p>\n

Varelas Lab Home<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Complete List of Published Work in MyBibliography   Varelas Lab Home<\/p>\n","protected":false},"author":1191,"featured_media":0,"parent":14902,"menu_order":4,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/wp-json\/wp\/v2\/pages\/16508"}],"collection":[{"href":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/wp-json\/wp\/v2\/users\/1191"}],"replies":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/wp-json\/wp\/v2\/comments?post=16508"}],"version-history":[{"count":50,"href":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/wp-json\/wp\/v2\/pages\/16508\/revisions"}],"predecessor-version":[{"id":19700,"href":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/wp-json\/wp\/v2\/pages\/16508\/revisions\/19700"}],"up":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/wp-json\/wp\/v2\/pages\/14902"}],"wp:attachment":[{"href":"https:\/\/www.bumc.bu.edu\/biochemcellbio\/wp-json\/wp\/v2\/media?parent=16508"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}