{"id":9273,"date":"2021-09-20T20:30:14","date_gmt":"2021-09-21T00:30:14","guid":{"rendered":"https:\/\/www.bumc.bu.edu\/anatneuro\/?page_id=9273"},"modified":"2025-03-04T15:35:18","modified_gmt":"2025-03-04T20:35:18","slug":"jennifer-luebke","status":"publish","type":"page","link":"https:\/\/www.bumc.bu.edu\/anatneuro\/jennifer-luebke\/","title":{"rendered":"Jennifer Luebke"},"content":{"rendered":"<\/div>\n<p><!-- ___________________Navbar___________________ --><\/p>\n<div id=\"navvy\"><\/div>\n<p><script type=\"text\/javascript\" src=\"\/anatneuro\/files\/2023\/08\/nav-08-2023.js\"><\/script><\/p>\n<p><!-- ___________________Banner___________________ --><\/p>\n<div class=\"mobile-title mobile-banner\">\n<p class=\"mobile-header\">Jennifer Luebke<\/p>\n<\/div>\n<div class=\"profile-parallax\">\n<div class=\"true-nav nav-border\"><\/div>\n<div style=\"width: 40%; float: left;\" class=\"title-padding\">\n<p class=\"title-header\">Jennifer Luebke<\/p>\n<p class=\"title-header2\" style=\"text-align: left;\">Professor<\/p>\n<\/div>\n<div style=\"width: 40%; float: right;\">\n<img loading=\"lazy\" style=\"padding-top: 50px;\" width=\"320\" height=\"320\" src=\"\/anatneuro\/files\/2021\/04\/jl.png\" alt=\"\">\n<\/div>\n<\/div>\n<p><!-- ___________________Profiles___________________ --><\/p>\n<div class=\"universal-pad\">\n<div class=\"col-md-8\">\n<p>Dr. Luebke received her doctorate in Anatomy &amp; Neurobiology from Chobanian &#038; Avedisian School of Medicine. She completed a first postdoctoral fellowship in neurophysiology at Harvard Medical School and a second postdoctoral fellowship in neurophysiology at Tufts University School of Medicine and then joined the Departments Anatomy &amp; Neurobiology and of Psychiatry at CAMED. Dr. Luebke maintains a laboratory in which whole-cell patch-clamp and intracellular filling techniques are used to examine the electrophysiological and morphological properties of neurons in in vitro slices of monkey and transgenic mouse neocortex.&nbsp; Research is focused on action potential firing patterns (and underlying ionic currents), glutamatergic and GABAergic synaptic response properties and detailed dendritic architecture.&nbsp; Data from single neurons are incorporated into computational models in collaboration with mathematicians at Mt. Sinai School of Medicine.&nbsp; In addition, collaborations are ongoing with investigators at CAMED who use molecular biological (single cell PCR and microarray) and electron microscopic (ultrastructural analysis) techniques to examine cells from which recordings are obtained. Overall goals include: 1) to examine the individual and network properties of cells in the prefrontal cortex; 2) to determine the effects of normal aging on these properties in the rhesus monkey, and; 3) to determine the effects of tau and amyloid on these properties in transgenic mouse models of Alzheimer\u2019s disease.&nbsp; Dr. Luebke\u2019s research is funded by the NIH.<\/p>\n<p>Dr. Luebke is a Waterhouse Professor and Chair of the Department.<\/p>\n<p><strong>Lab:&nbsp;<\/strong><a title=\"Laboratory of Cellular Neurobiology\" href=\"https:\/\/www.bumc.bu.edu\/anatneuro\/luebke-lab-2\/\" target=\"_self\" rel=\"noopener noreferrer\"><span class=\"standard\"><span>Laboratory of Cellular Neurobiology<\/span><\/span><\/a><\/p>\n<p><strong>CV:<\/strong><span>&nbsp;<\/span><a href=\"\/anatneuro\/files\/2021\/05\/JL-CV-2-1-21.pdf\">Luebke, Ph.D. \u2014 CV<\/a><\/p>\n<\/div>\n<div class=\"col-md-4\">\n<div class=\"block-pad\">\n<div class=\"block\">\n<p style=\"font-weight: bold;\">RESEARCH:<\/p>\n<p style=\"text-align: left;\">cortical neurons, normal and pathological aging, cerebral cortex<\/p>\n<p style=\"font-weight: bold;\">OFFICE:<\/p>\n<p>Office: X-314; Lab: X-317, 650 Albany St., CAMED<\/p>\n<p style=\"font-weight: bold;\">EMAIL:<\/p>\n<p>jluebke@bu.edu<\/p>\n<p style=\"font-weight: bold;\">PHONE:<\/p>\n<p>617-358-2200<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div style=\"padding-bottom: 20px;\">\n<a href=\"https:\/\/www.bumc.bu.edu\/anatneuro\/faculty\/\" class=\"btn\" style=\"width: 60vw;\"><br \/>\n  <span class=\"gradient-btn\">Faculty<\/span><br \/>\n<\/a>\n<\/div>\n<style>\n<p>article.post-12186 {\n   display: none;\n}<\/p>\n<p>\/* ----------------Blocks---------------- *\/<\/p>\n<p>.block {\n    background-color: #ffffff;\n    padding: 15px;\n    margin: auto;\n    height: 550px;\n    width: 300px;\n    border-radius: 3px;\n    align-items: center;\n    z-index: 2;\n    box-shadow: -50px 0 100px -50px #808080, 50px 0 100px -50px #808080;\n}<\/p>\n<p>.block-pad {\n    margin-top: 20px;\n    margin-bottom: 20px;\n}<\/p>\n<p>@media only screen and (min-width: 760px) {\n\t.block {\n\t\twidth: 300px;\n             height: 550px;\n\t}\n}<\/p>\n<p>.block h1 {\n    padding-bottom: 5px;\n    font-size: 24px;\n    text-align: center;\n}<\/p>\n<p>\/* ----------------Profile---------------- *\/<\/p>\n<p>.side-info {\n    background-color: #ffffff;\n}<\/p>\n<p>.universal-pad {\n    margin: 25px;\n    margin-left: 10vw;\n    margin-right: 10vw;\n}<\/p>\n<p>.firstinfo{\n  display: flex;\n  justify-content: center;\n  align-items: center;\n}<\/p>\n<p>.content1 {\n  position: relative;\n  animation: animatop 0.9s cubic-bezier(0.425, 1.14, 0.47, 1.125) forwards;\n  margin-left: 12vw;\n  margin-top: 10px;\n  margin-bottom: 10px;\n}<\/p>\n<p>.card {\n  width: 70vw;\n  min-height: 100px;\n  padding: 20px;\n  border-radius: 3px;\n  background-color: white;\n  box-shadow: 0px 10px 20px rgba(0, 0, 0, 0.2);\n  position: relative;\n  overflow: hidden;\n}\n.card:after {<\/p>\n<p>}<\/p>\n<p>.firstinfo {\n  flex-direction: row;\n  z-index: 2;\n  position: relative;\n}\n.firstinfo img {\n  display: none;\n}\n.firstinfo .profileinfo {\n  padding: 0px 20px;\n}\n.firstinfo .profileinfo h1 {\n  font-size: 35px;\n}\n.firstinfo .profileinfo h3 {\n  font-size: 20px;\n  color: #262262;\n  font-style: italic;\n}\n.firstinfo .profileinfo p.bio {\n  padding: 10px 0px;\n  color: #5A5A5A;\n  line-height: 1.2;\n  font-style: initial;\n}<\/p>\n<p>@keyframes animatop {\n  0% {\n    opacity: 0;\n    bottom: -500px;\n  }\n  100% {\n    opacity: 1;\n    bottom: 0px;\n  }\n}\n@keyframes animainfos {\n  0% {\n    bottom: 10px;\n  }\n  100% {\n    bottom: -42px;\n  }\n}\n@keyframes rotatemagic {\n  0% {\n    opacity: 0;\n    transform: rotate(0deg);\n    top: -24px;\n    left: -253px;\n  }\n  100% {\n    transform: rotate(-30deg);\n    top: -24px;\n    left: -78px;\n  }\n}<\/p>\n<p>@media only screen and (min-width: 900px) {\n.card:after {\n  content: \"\";\n  display: block;\n  width: 190px;\n  height: 300px;\n  background: #262262;\n  position: absolute;\n  animation: rotatemagic 0.75s cubic-bezier(0.425, 1.04, 0.47, 1.105) 1s both;\n}<\/p>\n<p>.firstinfo img {\n  border-radius: 50%;\n  width: 120px;\n  height: 120px;\ndisplay: block;\n}<\/p>\n<p>}\n\/* ----------------Animated Button---------------- *\/<\/p>\n<p>.gradient-btn {\n  \/* Fallback: Set a background color. *\/\n  background-color: #262262;<\/p>\n<p>  \/* Create the gradient. *\/\n  background-image: linear-gradient(\n    45deg,\n    #ffffff 50%,\n    #262262 50%\n  );<\/p>\n<p>  \/* Set the background size and repeat properties. *\/\n  background-size: 270%;\n  background-repeat: repeat;\n  background-position: top right;<\/p>\n<p>  \/* Use the text as a mask for the background. *\/\n  \/* This will show the gradient as a text color rather than element bg. *\/\n  -webkit-background-clip: text;\n  -webkit-text-fill-color: transparent; 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Neurobiology from Chobanian &#038; Avedisian School of Medicine. She completed a first postdoctoral fellowship in neurophysiology at Harvard Medical School and a second postdoctoral fellowship in neurophysiology at Tufts University School of Medicine and then joined the Departments Anatomy &amp; Neurobiology and [&hellip;]<\/p>\n","protected":false},"author":18550,"featured_media":0,"parent":0,"menu_order":46,"comment_status":"closed","ping_status":"closed","template":"page-templates\/no-sidebars.php","meta":[],"_links":{"self":[{"href":"https:\/\/www.bumc.bu.edu\/anatneuro\/wp-json\/wp\/v2\/pages\/9273"}],"collection":[{"href":"https:\/\/www.bumc.bu.edu\/anatneuro\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.bumc.bu.edu\/anatneuro\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/anatneuro\/wp-json\/wp\/v2\/users\/18550"}],"replies":[{"embeddable":true,"href":"https:\/\/www.bumc.bu.edu\/anatneuro\/wp-json\/wp\/v2\/comments?post=9273"}],"version-history":[{"count":15,"href":"https:\/\/www.bumc.bu.edu\/anatneuro\/wp-json\/wp\/v2\/pages\/9273\/revisions"}],"predecessor-version":[{"id":12507,"href":"https:\/\/www.bumc.bu.edu\/anatneuro\/wp-json\/wp\/v2\/pages\/9273\/revisions\/12507"}],"wp:attachment":[{"href":"https:\/\/www.bumc.bu.edu\/anatneuro\/wp-json\/wp\/v2\/media?parent=9273"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}