Lin L, Osan R, Tsien JZ. (2006) Organizing principles of real-time memory encoding: neural clique assemblies and universal neural codes. Trends Neurosci.: 2006 :48-57[ PDF ]

Cui Z, Lindl KA, Mei B, Zhang S, Tsien JZ. (2005) Requirement of NMDA receptor reactivation for consolidation and storage of nondeclarative taste memory revealed by inducible NR1 knockout. Eur J Neurosci.: 22 :755-63 [ PDF ]

Lin L, Osan R, Shoham S, Jin W, Zuo W, and Tsien JZ. (2005). Identification of network-level coding units for real-time representation of episodic experiences in the hippocampus. Proc Natl Acad Sci U S A. : 102: 6125-6130 [ PDF ]

Cui ZZ, Wang H, Tan Y, Zaia K, Zhang S, and Tsien JZ. (2004). Inducible and reversible NR1 knockout reveals crucial role of the NMDA receptor in preserving remote memories in the brain. Neuron: 41: 781-793. [ PDF ]

Feng R, Wang H, Wang J, Shrom D, Zeng X, Tsien JZ. (2004). Forebrain degeneration and ventricle enlargement caused by double knockout of Alzheimer's presenilin-1 and presenilin-2. Proc Natl Acad Sci U S A : 101: 8162-7. [ PDF ]

Wang H, Shimizu E, Tang YP, Cho M, Kyin M, Zuo W, Robinson DA, Alaimo PJ, Zhang C, Morimoto H, Zhuo M, Feng R, Shokat KM, Tsien JZ (2003). Inducible protein knockout reveals temporal requirement of CaMKII reactivation for memory consolidation in the brain. PNAS 100 :4287-4292. [ PDF ]

Wittenberg GM, Tsien JZ (2002). An emerging molecular and cellular framework for memory processing by the hippocampus. Trends Neurosci. 25 :501-505. [ PDF ]

Feng R, Rampon C, Tang YP, Shrom D, Jin J, Kyin M, Sopher B, Miller MW, Ware CB, Martin GM, Kim SH, Langdon RB, Sisodia SS, Tsien JZ (2001). Deficient neurogenesis in forebrain-specific presenilin-1 knockout mice is associated with reduced clearance of hippocampal memory traces. Neuron 32 :911-926. [ PDF ]

Mody M, Cao Y, Cui Z, Tay KY, Shyong A, Shimizu E, Pham K, Schultz P, Welsh D, Tsien JZ (2001). Genome-wide gene expression profiles of the developing mouse hippocampus. PNAS 98 :8862-8867. [ PDF ]

Shimizu E, Tang YP, Rampon C, Tsien JZ (2000). NMDA receptor-dependent synaptic reinforcement as a crucial process for memory consolidation. Science 290 :1170-1174. [ PDF ]

Bishop AC, Ubersax JA, Petsch DT, Matheos DP, Gray NS, Blethrow J, Shimizu E, Tsien JZ, Schultz PG, Rose MD, Wood JL, Morgan DO, Shokat KM (2000). A chemical switch for inhibitor-sensitive alleles of any protein kinase. Nature 407 :395-401. [ PDF ]

Tsien JZ (2000). Building a brainier mouse. Scientific American 282 :62-68. [ PDF ]

Tsien JZ (2000). Linking Hebb's coincidence-detection to memory formation. Curr. Opin. Neurobiol. 10 :266-273. [ PDF ]

Rampon C, Tang YP, Goodhouse J, Shimizu E, Kyin M, Tsien JZ (2000). Enrichment induces structural changes and recovery from nonspatial memory deficits in CA1 NMDAR1-knockout mice. Nat Neurosci. 3 :238-244. [ PDF ]

Tang YP, Shimizu E, Dube GR, Rampon C, Kerchner GA, Zhuo M, Liu G, Tsien JZ (1999). Genetic enhancement of learning and memory in mice. Nature 401 :63-69. [ PDF ]

Tsien JZ, Chen DF, Gerber D, Tom C, Mercer EH, Anderson DJ, Mayford M, Kandel ER, Tonegawa S (1996). Subregion- and cell type-restricted gene knockout in mouse brain. Cell 87 :1317-1326. [ PDF ]

Tsien JZ, Huerta PT, Tonegawa S (1996). The essential role of hippocampal CA1 NMDA receptor-dependent synaptic plasticity in spatial memory. Cell 87 :1327-1338. [ PDF ]

McHugh TJ, Blum KI, Tsien JZ, Tonegawa S, Wilson MA (1996) Impaired hippocampal representation of space in CA1-specific NMDAR1 knockout mice. Cell 87 :1339-1349. [ PDF ]

Tsien JZ, Gilbert ME, Colicos MA, Kandel ER, and Kuhl D (1993). Tissue-plasminogen activator is induced as an immediate-early gene during seizure, kindling and long-term potentiation. Nature 361 : 453-457.