HUMAN iPSCs
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| iPSC Type/Disease |
Name/Designation |
Description |
iPSC Reprogramming Method |
Starting Materials |
Karyotype |
Immunofluorescence Staining for Pluripotency Markers |
Reference |
| Alpha-1 PiZZ |
RC2 100-2 |
Alpha-1 Antitrypsin Deficiency, Genotype PiZZ |
EF1a-hSTEMCCA4 loxp lentiviral infection |
Dermal Fibroblasts |
ND |
Yes |
Kotton Lab |
| Alpha-1 PiZZ |
RC2 100-7 |
Alpha-1 Antitrypsin Deficiency, Genotype PiZZ |
EF1a-hSTEMCCA4 loxp lentiviral infection |
Dermal Fibroblasts |
ND |
Yes |
Kotton Lab |
| Alpha-1 PiZZ |
RC2 100-13 |
Alpha-1 Antitrypsin Deficiency, Genotype PiZZ |
EF1a-hSTEMCCA4 loxp lentiviral infection |
Dermal Fibroblasts |
ND |
Yes |
Kotton Lab |
| Alpha-1 PiZZ |
RC2 104 |
Alpha-1 Antitrypsin Deficiency, Genotype PiZZ |
EF1a-hSTEMCCA4 loxp lentiviral infection |
Dermal Fibroblasts |
ND |
Yes |
Somers A. Stem Cells 2011 |
| ALS |
ALS1 |
kAMYOTROPHIC LATERAL SCLEROSIS 1, TDP43 mutation |
EF1a-hSTEMCCA4 loxp lentiviral infection |
Dermal Fibroblast Corriell #ND32947 |
ND |
Yes |
Murphy Lab |
| Amyloidosis TTR |
TTR1 |
TRANSTHYRETIN; TTR amyloidosis, L55P mutation |
EF1a-hSTEMCCA4 loxp lentiviral infection |
Dermal Fibroblast Corriell #GM01998 |
46XX |
Yes |
Murphy Lab |
| Beta Thal |
THAL1-1 |
b-thalassemia (Glu26Lys) |
EF1a-hSTEMCCA4 loxp lentiviral infection |
PBMCs |
ND |
Yes |
Mostoslavsky Lab |
| Beta Thal |
THAL2-1 |
b-thalassemia (Glun39Term) |
EF1a-hSTEMCCA4 loxp lentiviral infection |
PBMCs |
ND |
Yes |
Mostoslavsky Lab |
| BMPR2 het |
BMPR2 |
hiPSC from Patient with Primary Pulmonary Hypertension (BMPR2 het mutant) |
EF1a-hSTEMCCA4 loxp lentiviral infection |
Dermal Fibroblasts |
46XX |
Yes |
Kotton Lab |
| ChILD-ABCA3 |
ABCA3 (SP300) |
hiPSC ChILD ABCA3 deficient, homo E609K, Pt 2-0300 |
EF1a-hSTEMCCA4 loxp lentiviral infection |
Dermal Fibroblasts |
ND |
Yes |
Kotton Lab |
| ChILD-NKX2.1 het |
T1 1Cr NKX2.1 Pt 1 |
hiPSC ChILD NKX2.1 het (Brain-Lung-Thyroid Syndrome) |
EF1a-hSTEMCCA4 loxp lentiviral infection |
Dermal Fibroblasts |
46XX |
Yes |
Kotton Lab |
| ChILD-NKX2.1 het |
T3 2Cr NKX2.1 Pt 3 |
hiPSC ChILD NKX2.1 het deletion (Brain-Lung-Thyroid Syndrome); large deletion |
EF1a-hSTEMCCA4 loxp lentiviral infection |
Dermal Fibroblasts |
46XX |
Yes |
Kotton Lab |
| ChILD-NKX2.1 het |
T4 32Cr NKX2.1 Pt 4 |
hiPSC ChILD NKX2.1 mutant (Brain-Lung-Thyroid Syndrome) |
EF1a-hSTEMCCA4 loxp lentiviral infection |
Dermal Fibroblasts |
46XY |
Yes |
Kotton Lab |
| ChILD-SPB homo |
SP 212 1Cr3 SPB |
hiPSC ChILD SPB deficient ,121ins2, Pt 2-0212 |
EF1a-hSTEMCCA4 loxp lentiviral infection |
Dermal Fibroblasts |
46XX |
Yes |
Kotton Lab |
| ChILD-SPC |
S1 2Cr SPC |
hiPSC ChILD SPC mutant |
EF1a-hSTEMCCA4 loxp lentiviral infection |
Dermal Fibroblasts |
46XX |
Yes |
Kotton Lab |
| Cystic Fibrosis DF508 |
RC2 200 |
hiPSC DF508 CFTR Homozygous (CYSTIC FIBROSIS) |
EF1a-hSTEMCCA4 loxp lentiviral infection |
Dermal Fibroblasts |
ND |
Yes |
Somers A. Stem Cells 2011 |
| Cystic Fibrosis DF508 |
RC2 201 |
hiPSC DF508 CFTR Homozygous (CYSTIC FIBROSIS) |
EF1a-hSTEMCCA4 loxp lentiviral infection |
Dermal Fibroblasts |
ND |
Yes |
Somers A. Stem Cells 2011 |
| Cystic Fibrosis DF508 |
RC2 203 |
hiPSC DF508 CFTR Homozygous (CYSTIC FIBROSIS) |
EF1a-hSTEMCCA4 loxp lentiviral infection |
Dermal Fibroblasts |
ND |
Yes |
Somers A. Stem Cells 2011 |
| FAP |
FAP6965-1 |
Familial adenomatous polyposis; FAP (P1542X) |
EF1a-hSTEMCCA4 loxp lentiviral infection |
Dermal Fibroblasts (Coriell# GM06965) |
46XX |
Yes |
Mostoslavsky Lab |
| FAP |
FAP3948-1 |
FAP (Q541X) |
EF1a-hSTEMCCA4 loxp lentiviral infection |
Dermal Fibroblasts (Coriell# GM03948) |
46XX |
Yes |
Mostoslavsky Lab |
| Giant platelet syndrome |
GM10461 |
GIANT PLATELET SYNDROME |
EF1a-hSTEMCCA4 loxp lentiviral infection |
Dermal Fibroblast Corriell #GM10461 |
ND |
Yes |
Murphy Lab |
| Hemochromatosis |
HC1-1 |
Hemochromatosis (H63D/V256I) |
EF1a-hSTEMCCA4 loxp lentiviral infection |
Dermal Fibroblasts |
46XY |
Yes |
Mostoslavsky Lab |
| Hemochromatosis |
HC2-1 |
Hemochromatosis (C282Y) |
EF1a-hSTEMCCA4 loxp lentiviral infection |
Dermal Fibroblasts |
46XX |
Yes |
Mostoslavsky Lab |
| Hemochromatosis |
HC3-1 |
Hemochromatosis (C282Y) |
EF1a-hSTEMCCA4 loxp lentiviral infection |
Dermal Fibroblasts |
46XX |
Yes |
Mostoslavsky Lab |
| K chanell polymorphisms |
HR II 3Cr5 |
hIPSC Control- mother of Long QT3 family; benign K channel polymorphism KCNH2 K897T |
EF1a-hSTEMCCA4 loxp lentiviral infection |
Dermal Fibroblasts |
46XX |
Yes |
Kotton Lab |
| K chanell polymorphisms |
HR II 5A |
hIPSC Control- mother of Long QT3 family; benign K channel polymorphism KCNH2 K897T (pe-excision) |
EF1a-hSTEMCCA4 loxp lentiviral infection |
Dermal Fibroblasts |
46XX |
Yes |
Kotton Lab |
| K chanell polymorphisms |
HR II 9A |
hIPSC Control- mother of Long QT3 family; benign K channel polymorphism KCNH2 K897T (pre-excision) |
EF1a-hSTEMCCA4 loxp lentiviral infection |
Dermal Fibroblasts |
46XX |
Yes |
Kotton Lab |
| Long QT3 Syndrome |
OA6 9Cr8 |
hIPSC Long QT3 syndrome (Na channel SCN5A F1473C; and K polymorphism) |
EF1a-hSTEMCCA4 loxp lentiviral infection |
Dermal Fibroblasts |
46XY |
Yes |
Kotton Lab |
| Long QT3 Syndrome |
OA6 17Cr8 |
hIPSC Long QT3 syndrome (Na channel SCN5A F1473C; and K polymorphism) |
EF1a-hSTEMCCA4 loxp lentiviral infection |
Dermal Fibroblasts |
46XY |
Yes |
Kotton Lab |
| Long QT3 Syndrome |
OA6 22Cr8 |
hIPSC Long QT3 syndrome (Na channel SCN5A F1473C; and K polymorphism) |
EF1a-hSTEMCCA4 loxp lentiviral infection |
Dermal Fibroblasts |
46XY |
Yes |
Kotton Lab |
| Normal |
HR I 2 |
hIPSC Control- father of Long QT3 family (pre-cre excision) |
EF1a-hSTEMCCA4 loxp lentiviral infection |
Dermal Fibroblasts |
46XY |
Yes |
Kotton Lab |
| Normal |
HR I 2Cr2R |
hIPSC Control- father of Long QT3 family (post-cre excision) |
EF1a-hSTEMCCA4 loxp lentiviral infection |
Dermal Fibroblasts |
46XY |
Yes |
Kotton Lab |
| Normal |
HR I 7A |
hIPSC Control- father of Long QT3 family (pre-cre excision) |
EF1a-hSTEMCCA4 loxp lentiviral infection |
Dermal Fibroblasts |
46XY |
Yes |
Kotton Lab |
| Normal |
HR I 15 |
hIPSC Control- father of Long QT3 family (pre-cre excision) |
EF1a-hSTEMCCA4 loxp lentiviral infection |
Dermal Fibroblasts |
46XY |
Yes |
Kotton Lab |
| Scleroderma |
SCL1 |
hIPSC SCLERODERMA; Pt1 |
EF1a-hSTEMCCA4 loxp lentiviral infection |
Dermal Fibroblasts |
ND |
Yes |
Somers A. Stem Cells 2011 |
| Scleroderma |
SCL2 |
hIPSC SCLERODERMA; Pt1 |
EF1a-hSTEMCCA4 loxp lentiviral infection |
Dermal Fibroblasts |
ND |
Yes |
Somers A. Stem Cells 2011 |
| Scleroderma |
SCL3 |
hIPSC SCLERODERMA; Pt1 |
EF1a-hSTEMCCA4 loxp lentiviral infection |
Dermal Fibroblasts |
ND |
Yes |
Somers A. Stem Cells 2011 |
| Sickle Cell SS |
SS-002-1 |
Sikle Cell Disease |
EF1a-hSTEMCCA4 loxp lentiviral infection |
PBMCs |
ND |
Yes |
Murphy/Mostoslavsky Lab |
| Sickle Cell SS |
SS-002-2 |
Sikle Cell Disease |
EF1a-hSTEMCCA4 loxp lentiviral infection |
PBMCs |
ND |
Yes |
Murphy/Mostoslavsky Lab |
| Sickle Cell SS |
SS-002-3 |
Sikle Cell Disease |
EF1a-hSTEMCCA4 loxp lentiviral infection |
PBMCs |
ND |
Yes |
Murphy/Mostoslavsky Lab |
| Sickle Cell SS |
SS-004-1 |
Sikle Cell Disease |
EF1a-hSTEMCCA4 loxp lentiviral infection |
PBMCs |
ND |
Yes |
Murphy/Mostoslavsky Lab |
| Sickle Cell SS |
SS-004-2 |
Sikle Cell Disease |
EF1a-hSTEMCCA4 loxp lentiviral infection |
PBMCs |
ND |
Yes |
Murphy/Mostoslavsky Lab |
| Sickle Cell SS |
SS-004-3 |
Sikle Cell Disease |
EF1a-hSTEMCCA4 loxp lentiviral infection |
PBMCs |
ND |
Yes |
Murphy/Mostoslavsky Lab |
| Sickle Cell SS |
SS-005-1 |
Sikle Cell Disease |
EF1a-hSTEMCCA4 loxp lentiviral infection |
PBMCs |
ND |
Yes |
Murphy/Mostoslavsky Lab |
| Sickle Cell SS |
SS-005-2 |
Sikle Cell Disease |
EF1a-hSTEMCCA4 loxp lentiviral infection |
PBMCs |
ND |
Yes |
Murphy/Mostoslavsky Lab |
| Sickle Cell SS |
SS-005-3 |
Sikle Cell Disease |
EF1a-hSTEMCCA4 loxp lentiviral infection |
PBMCs |
ND |
Yes |
Murphy/Mostoslavsky Lab |
| Sickle Cell SS |
SS-006-1 |
Sikle Cell Disease |
EF1a-hSTEMCCA4 loxp lentiviral infection |
PBMCs |
ND |
Yes |
Murphy/Mostoslavsky Lab |
| Sickle Cell SS |
SS-006-2 |
Sikle Cell Disease |
EF1a-hSTEMCCA4 loxp lentiviral infection |
PBMCs |
ND |
Yes |
Murphy/Mostoslavsky Lab |
| Sickle Cell SS |
SS-006-3 |
Sikle Cell Disease |
EF1a-hSTEMCCA4 loxp lentiviral infection |
PBMCs |
ND |
Yes |
Murphy/Mostoslavsky Lab |
| Sickle Cell SS |
SS-008-1 |
Sikle Cell Disease |
EF1a-hSTEMCCA4 loxp lentiviral infection |
PBMCs |
ND |
Yes |
Murphy/Mostoslavsky Lab |
| Sickle Cell SS |
SS-008-2 |
Sikle Cell Disease |
EF1a-hSTEMCCA4 loxp lentiviral infection |
PBMCs |
ND |
Yes |
Murphy/Mostoslavsky Lab |
| Sickle Cell SS |
SS-008-3 |
Sikle Cell Disease |
EF1a-hSTEMCCA4 loxp lentiviral infection |
PBMCs |
ND |
Yes |
Murphy/Mostoslavsky Lab |
| Sickle Cell SS |
SS-009-1 |
Sikle Cell Disease |
EF1a-hSTEMCCA4 loxp lentiviral infection |
PBMCs |
ND |
Yes |
Murphy/Mostoslavsky Lab |
| Sickle Cell SS |
SS-009-2 |
Sikle Cell Disease |
EF1a-hSTEMCCA4 loxp lentiviral infection |
PBMCs |
ND |
Yes |
Murphy/Mostoslavsky Lab |
| Sickle Cell SS |
SS-009-3 |
Sikle Cell Disease |
EF1a-hSTEMCCA4 loxp lentiviral infection |
PBMCs |
ND |
Yes |
Murphy/Mostoslavsky Lab |
| Sickle Cell SS |
SS-012-1 |
Sikle Cell Disease |
EF1a-hSTEMCCA4 loxp lentiviral infection |
PBMCs |
ND |
Yes |
Murphy/Mostoslavsky Lab |
| Sickle Cell SS |
SS-012-2 |
Sikle Cell Disease |
EF1a-hSTEMCCA4 loxp lentiviral infection |
PBMCs |
ND |
Yes |
Murphy/Mostoslavsky Lab |
| Sickle Cell SS |
SS-012-3 |
Sikle Cell Disease |
EF1a-hSTEMCCA4 loxp lentiviral infection |
PBMCs |
ND |
Yes |
Murphy/Mostoslavsky Lab |
| Sickle Cell SS |
SS-013-1 |
Sikle Cell Disease |
EF1a-hSTEMCCA4 loxp lentiviral infection |
PBMCs |
ND |
Yes |
Murphy/Mostoslavsky Lab |
| Sickle Cell SS |
SS-013-2 |
Sikle Cell Disease |
EF1a-hSTEMCCA4 loxp lentiviral infection |
PBMCs |
ND |
Yes |
Murphy/Mostoslavsky Lab |
| Sickle Cell SS |
SS-013-3 |
Sikle Cell Disease |
EF1a-hSTEMCCA4 loxp lentiviral infection |
PBMCs |
ND |
Yes |
Murphy/Mostoslavsky Lab |
| Sickle Cell SS |
SS-014-1 |
Sikle Cell Disease |
EF1a-hSTEMCCA4 loxp lentiviral infection |
PBMCs |
ND |
Yes |
Murphy/Mostoslavsky Lab |
| Sickle Cell SS |
SS-014-2 |
Sikle Cell Disease |
EF1a-hSTEMCCA4 loxp lentiviral infection |
PBMCs |
ND |
Yes |
Murphy/Mostoslavsky Lab |
| Sickle Cell SS |
SS-014-3 |
Sikle Cell Disease |
EF1a-hSTEMCCA4 loxp lentiviral infection |
PBMCs |
ND |
Yes |
Murphy/Mostoslavsky Lab |
| Sickle Cell SS |
SS-015-1 |
Sikle Cell Disease |
EF1a-hSTEMCCA4 loxp lentiviral infection |
PBMCs |
ND |
Yes |
Murphy/Mostoslavsky Lab |
| Sickle Cell SS |
SS-015-2 |
Sikle Cell Disease |
EF1a-hSTEMCCA4 loxp lentiviral infection |
PBMCs |
ND |
Yes |
Murphy/Mostoslavsky Lab |
| Sickle Cell SS |
SS-015-3 |
Sikle Cell Disease |
EF1a-hSTEMCCA4 loxp lentiviral infection |
PBMCs |
ND |
Yes |
Murphy/Mostoslavsky Lab |
| Sickle Cell SS |
SS-016-1 |
Sikle Cell Disease |
EF1a-hSTEMCCA4 loxp lentiviral infection |
PBMCs |
ND |
Yes |
Murphy/Mostoslavsky Lab |
| Sickle Cell SS |
SS-016-2 |
Sikle Cell Disease |
EF1a-hSTEMCCA4 loxp lentiviral infection |
PBMCs |
ND |
Yes |
Murphy/Mostoslavsky Lab |
| Sickle Cell SS |
SS-016-3 |
Sikle Cell Disease |
EF1a-hSTEMCCA4 loxp lentiviral infection |
PBMCs |
ND |
Yes |
Murphy/Mostoslavsky Lab |
| Sickle Cell SS |
SS-018-1 |
Sikle Cell Disease |
EF1a-hSTEMCCA4 loxp lentiviral infection |
PBMCs |
ND |
Yes |
Murphy/Mostoslavsky Lab |
| Sickle Cell SS |
SS-018-2 |
Sikle Cell Disease |
EF1a-hSTEMCCA4 loxp lentiviral infection |
PBMCs |
ND |
Yes |
Murphy/Mostoslavsky Lab |
| Sickle Cell SS |
SS-018-3 |
Sikle Cell Disease |
EF1a-hSTEMCCA4 loxp lentiviral infection |
PBMCs |
ND |
Yes |
Murphy/Mostoslavsky Lab |
| Sickle Cell SS |
SS-019-1 |
Sikle Cell Disease |
EF1a-hSTEMCCA4 loxp lentiviral infection |
PBMCs |
ND |
Yes |
Murphy/Mostoslavsky Lab |
| Sickle Cell SS |
SS-019-2 |
Sikle Cell Disease |
EF1a-hSTEMCCA4 loxp lentiviral infection |
PBMCs |
ND |
Yes |
Murphy/Mostoslavsky Lab |
| Sickle Cell SS |
SS-019-3 |
Sikle Cell Disease |
EF1a-hSTEMCCA4 loxp lentiviral infection |
PBMCs |
ND |
Yes |
Murphy/Mostoslavsky Lab |
| Sickle Cell SS |
SS-024-1 |
Sikle Cell Disease |
EF1a-hSTEMCCA4 loxp lentiviral infection |
PBMCs |
ND |
Yes |
Murphy/Mostoslavsky Lab |
| Sickle Cell SS |
SS-024-2 |
Sikle Cell Disease |
EF1a-hSTEMCCA4 loxp lentiviral infection |
PBMCs |
ND |
Yes |
Murphy/Mostoslavsky Lab |
| Sickle Cell SS |
SS-024-3 |
Sikle Cell Disease |
EF1a-hSTEMCCA4 loxp lentiviral infection |
PBMCs |
ND |
Yes |
Murphy/Mostoslavsky Lab |
| Sickle Cell SS |
SS-025-1 |
Sikle Cell Disease |
EF1a-hSTEMCCA4 loxp lentiviral infection |
PBMCs |
ND |
Yes |
Murphy/Mostoslavsky Lab |
| Sickle Cell SS |
SS-025-2 |
Sikle Cell Disease |
EF1a-hSTEMCCA4 loxp lentiviral infection |
PBMCs |
ND |
Yes |
Murphy/Mostoslavsky Lab |
| Sickle Cell SS |
SS-025-3 |
Sikle Cell Disease |
EF1a-hSTEMCCA4 loxp lentiviral infection |
PBMCs |
ND |
Yes |
Murphy/Mostoslavsky Lab |
| Sickle Cell SS |
SS-028-1 |
Sikle Cell Disease |
EF1a-hSTEMCCA4 loxp lentiviral infection |
PBMCs |
ND |
Yes |
Murphy/Mostoslavsky Lab |
| Sickle Cell SS |
SS-028-2 |
Sikle Cell Disease |
EF1a-hSTEMCCA4 loxp lentiviral infection |
PBMCs |
ND |
Yes |
Murphy/Mostoslavsky Lab |
| Sickle Cell SS |
SS-028-3 |
Sikle Cell Disease |
EF1a-hSTEMCCA4 loxp lentiviral infection |
PBMCs |
ND |
Yes |
Murphy/Mostoslavsky Lab |
| Sickle Cell SS |
SS-029-1 |
Sikle Cell Disease |
EF1a-hSTEMCCA4 loxp lentiviral infection |
PBMCs |
ND |
Yes |
Murphy/Mostoslavsky Lab |
| Sickle Cell SS |
SS-029-2 |
Sikle Cell Disease |
EF1a-hSTEMCCA4 loxp lentiviral infection |
PBMCs |
ND |
Yes |
Murphy/Mostoslavsky Lab |
| Sickle Cell SS |
SS-029-3 |
Sikle Cell Disease |
EF1a-hSTEMCCA4 loxp lentiviral infection |
PBMCs |
ND |
Yes |
Murphy/Mostoslavsky Lab |
| Sickle Cell SS |
SS-032-1 |
Sikle Cell Disease |
EF1a-hSTEMCCA4 loxp lentiviral infection |
PBMCs |
ND |
Yes |
Murphy/Mostoslavsky Lab |
| Sickle Cell SS |
SS-032-2 |
Sikle Cell Disease |
EF1a-hSTEMCCA4 loxp lentiviral infection |
PBMCs |
ND |
Yes |
Murphy/Mostoslavsky Lab |
| Sickle Cell SS |
SS-035-1 |
Sikle Cell Disease |
EF1a-hSTEMCCA4 loxp lentiviral infection |
PBMCs |
ND |
Yes |
Murphy/Mostoslavsky Lab |
| Sickle Cell SS |
SS-035-2 |
Sikle Cell Disease |
EF1a-hSTEMCCA4 loxp lentiviral infection |
PBMCs |
ND |
Yes |
Murphy/Mostoslavsky Lab |
| Sickle Cell SS |
SS-035-3 |
Sikle Cell Disease |
EF1a-hSTEMCCA4 loxp lentiviral infection |
PBMCs |
ND |
Yes |
Murphy/Mostoslavsky Lab |
| Sickle Cell SS |
SS-036-1 |
Sikle Cell Disease |
EF1a-hSTEMCCA4 loxp lentiviral infection |
PBMCs |
ND |
Yes |
Murphy/Mostoslavsky Lab |
| Sickle Cell SS |
SS-036-2 |
Sikle Cell Disease |
EF1a-hSTEMCCA4 loxp lentiviral infection |
PBMCs |
ND |
Yes |
Murphy/Mostoslavsky Lab |
| Sickle Cell SS |
SS-036-3 |
Sikle Cell Disease |
EF1a-hSTEMCCA4 loxp lentiviral infection |
PBMCs |
ND |
Yes |
Murphy/Mostoslavsky Lab |
| Sickle Cell SS |
SS-037-1 |
Sikle Cell Disease |
EF1a-hSTEMCCA4 loxp lentiviral infection |
PBMCs |
ND |
Yes |
Murphy/Mostoslavsky Lab |
| Sickle Cell SS |
SS-038-1 |
Sikle Cell Disease |
EF1a-hSTEMCCA4 loxp lentiviral infection |
PBMCs |
ND |
Yes |
Murphy/Mostoslavsky Lab |
| Sickle Cell SS |
SS-038-2 |
Sikle Cell Disease |
EF1a-hSTEMCCA4 loxp lentiviral infection |
PBMCs |
ND |
Yes |
Murphy/Mostoslavsky Lab |
| Sickle Cell SS |
SS-038-3 |
Sikle Cell Disease |
EF1a-hSTEMCCA4 loxp lentiviral infection |
PBMCs |
ND |
Yes |
Murphy/Mostoslavsky Lab |