The Role of Notch Signaling in Renal Development (Dr. Bonegio)

Ramon Bonegio, M.D. works with Dr. David Salant and is completing a Ph.D. thesis on the role of notch signaling in renal development and the glomerular injury response.


  1. Aprahamian, T., Rifkin, I., Bonegio, R., Hugel, B., Freyssinet, J. M., Sato, K., Castellot, J. J., Jr., and Walsh, K. (2004). Impaired clearance of apoptotic cells promotes synergy between atherogenesis and autoimmune disease. J Exp Med 199, 1121-1131.
  2. Bonegio, R. G., Fuhro, R., Wang, Z., Valeri, C. R., Andry, C., Salant, D. J., and Lieberthal, W. (2005). Rapamycin ameliorates proteinuria-associated tubulointerstitial inflammation and fibrosis in experimental membranous nephropathy. J Am Soc Nephrol 16, 2063-2072.
  3. Bonegio, R.,Fuhro, R., Ragno, G., Robert Valeri, C., and Lieberthal, W. (2006). A comparison of the acute hemodynamic and delayed effects of 50% exchange transfusion with two different cross-linked hemoglobin based oxygen carrying solutions and Pentastarch. Artif Cells Blood Substit Immobil Biotechnol 34, 145-157.
  4. Aprahamian, T., Bonegio, R.,Rizzo, J., Perlman, H., Lefer, D. J., Rifkin, I. R., and Walsh, K. (2006). Simvastatin treatment ameliorates autoimmune disease associated with accelerated atherosclerosis in a murine lupus model. J Immunol 177, 3028-3034.

Book Chapters

  1. Bonegio, R. and Lieberthal W.: Cisplatin nephrotoxicity and analogues: Toxicology of the kidney – edited by Joan Tarloff and Larry Lash (3rd Ed.) Taylor and Francis (London) 2004

Primary teaching affiliate
of BU School of Medicine