Robin Ingalls M.D.
Office: 650 Albany St. 6th floor
Dr. Ingalls’ primary area of research is focused on understanding the immune defenses of the female genital tract. The area of mucosal immunology is relatively undeveloped, and the immunology of the reproductive system is a truly important area of study that impacts the treatment and prevention of STDs, including HIV, the social and economic burden of infertility, and development of vaccines and other immune modulating therapies. Dr. Ingalls’ research goals are currently focused on the role of TLRs and other aspects of innate immunity in the defense of the lower female urogenital tract to STDs. She has developed an in vitro model for studying the interaction of genital tract pathogens, specifically N. gonorrhoeae and C. trachomatis, with human epithelial cells derived from various levels of the female genital tract. In addition, her laboratory in collaboration with Drs. Genco and Freedman has recently begun both in vitro and in vivo studies on the impact of innate immunity on the development of C. pneumoniae-induced pneumonia and atherosclerosis. She also has a long-standing interest in bacterial sepsis, LPS signaling, and leukocyte integrins.