Andrew Henderson Ph.D.
Office: 650 Albany St. 6th floor
Research in the Henderson laboratory focuses on cellular mechanisms that regulate HIV replication and transcription. Active projects in the laboratory include elucidating T cell co-stimulatory signal transduction cascades that positively and negatively regulate HIV transcription, determining mechanisms by which HIV circumvents anti-inflammatory signals to promote HIV replication and AIDS-associated inflammatory diseases and characterizing the transcriptional status of HIV provirus in T cell and macrophage subsets. Although, HIV is the primary experimental system, research in Dr. Henderson’s laboratory provides general insights into signal transduction, tissue-specific gene expression, immune cell function and mechanisms that contribute to inflammatory disorders and autoimmunity.