Pi Day 2014

March 14th, 2014

Bring them if you’ve got them!


Congratulations to Dr. Arwa Badahdah on the successful defense of her Doctor of Science (D.Sc.) dissertation

March 2nd, 2014

Dr. Arwa Badahdah has successfully defended her DSc dissertation, “Effect of a
Salivary Peptide on the Structure of Bacterial Pili and Bacterial Adhesion to Host

Dr. Badahdah completed her research in a Physiology & Biophysics lab, and is a
member of the Oral Biology & Periodontology program at the BU Goldman School of
Dental Medicine.

She has passed her written Dental Board Exam, and will graduate in May 2014 with a
combined DDS / DSc degree.

Congratulations to Dr. Mengxiao Lu on a successful defense of her PhD dissertation

January 31st, 2014

Congratulations to Dr. Mengxiao Lu on a successful defense of her PhD dissertation “Structural Stability and Fusion of Human Low-Density Lipoproteins” (advisor: Dr. Gursky)

Dr. Barbara Seaton’s research is the on the cover of the November issue of Immunology

October 29th, 2013

The journal Immunology has published Dr. Seaton’s article titled; “The binding sites of monoclonal antibodies to the non-reducing end of Francisella tularensis O-antigen accommodate mainly the terminal saccharide.”

Drs. Lynne Coluccio and Hiroshi Tokuo have published a paper in Molecular Biology of the Cell on the regulation of cell-cell adhesion.

October 24th, 2013

The article is titled;”Myosin-1c regulates the dynamic stability of E-cadherin–based cell–cell contacts in polarized Madin–Darby canine kidney cells” and can be found in the September 15 issue of Molecular Biology of the Cell.

New article in Nature Letters by Prof. Chris Akey titled; “Structure of the SecY channel during initiation of protein translocation”.

October 24th, 2013

“Similar to passengers on an urban transit system, every protein made in the cell has a specific destination and function. Channels in cell membranes help direct these proteins to their appropriate target. Researchers at Boston University School of Medicine (BUSM) and their colleagues have now captured images of these channels as they open to allow proteins to pass through a membrane, while the proteins are being made. These findings are published as a Letter in Nature.”

More information here.

New J. Biol. Chem article on membrane remodeling by a viral protein

August 9th, 2013

Congratulations to Drs. Jing Wang and Esther Bullitt on their new publication in collaboration with Drs. J. Ptacek  and K. Kirkegaard,
Double-Membraned Liposomes Sculpted by Poliovirus 3AB Protein
now in press at the Journal of Biological Chemistry.

Congratulations to Mengxiao Lu, a PhD student in the Gursky lab.

July 11th, 2013

Congratulations to Mengxiao Lu, a PhD student  in the Gursky lab, who is a corresponding author on an invited review “Aggregation and fusion of low-density lipoproteins in vivo and in vitro” accepted for publication in BMC.

Physiology and Biophysics gets NIH grant to update NMR Facility!

July 11th, 2013

The BUSM has just been awarded a Shared Instrument Grant from the NIH to upgrade our Core Facility for Structural NMR.  The proposal  ”A Console Upgrade and Cryogenic Probe for a 500 MHz NMR System for Biomedical Research” will provide state-of-the art electronics and a superconducting probe that will increase the sensitivity of the instrument approximately ten-fold.  This will provide superior spectra with less instrument time and allow research on samples not possible with the current instrument.

The PI of the proposal is C. James McKnight and the Major Users are Assen Marintchev, James Hamilton, Christopher Akey and David Atkinson from the Department of Physiology and Biophysics.  The Major Users outside of Physiology and Biophysics are Susan Fisher (Microbiology), David Harris (Biochemistry), Erdjan Salih (Oral Biology) and Stephen Blacklow (Dana Farber Cancer Institute, Harvard Medical School).  The upgraded Facility will be managed by Jonathan Vural.

Here is a link to the Core Facility for Structural NMR:


Congratulations to Dr. Olga Gursky for receiving an NIH grant to study “Structural stability and functional remodeling of high-density lipoproteins”

July 9th, 2013

Congratulations to Dr. Olga Gursky for receiving a new RO1 grant to study “Structural stability and functional remodeling of high-density lipoproteins”.

March 14, 2014
Primary teaching affiliate
of BU School of Medicine