Seminar Series in the Department of Physiology & Biophysics

Spring 2014

Department of Physiology & Biophysics Seminar Series

Tuesdays 1:30, Room R103

Date Speaker Title & Host
1/14/14 John Samuelson, PhD
Goldman School of Dental Medicine
The low-hanging fruit of cyst and oocyst walls: strategies to discover the structural
components of the walls of parasitic protists
(Host: Esther Bullitt)
1/21/14 Mason Klein, PhD
Dept. of Physics, Harvard University
Cold avoidance, cold sensing, and cold circuits in the Drosophila larva
(Host: Chris Gabel)
2/4/14 Tyler Reddy, PhD
Dept. of Biochemistry, University of Oxford
Biophysical characterization of full-scale influenza and dengue virions
(Host: Barbara Seaton)
2/11/14 Barbara Corkey, PhD
Zoltan Kohn Professor of Medicine, BUSM
Redox Regulation in Obesity and Diabetes
(Host: Haya Herscovitz)
2/25/14 Olivier Kocher, PhD
Pathology, Harvard Medical School
Regulation of the HDL receptor SR-BI expression by the multi PDZ domain adaptor protein PDZK1
(Host: David Atkinson)
3/11/14 Zvonimir Dogic, PhD
Dept of Physics, Brandeis University
From Molecular Motors and Microtubules to Synthetic Cilia and the Beyond
(Host: Bill Lehman)
3/18/14
*Time: 9:30am
Daniel Saltzberg
BU Physiology & Biophysics Dept.
Thesis Defense: Substrate Specificity and Conformational Activation Mechanism of Beta-Phosphoglucomutase
(Advisor: Karen Allen)
3/25/14 Andrei Korostelev, PhD
UMass Medical Center
TBA
(Host: Chris Akey)
*Postponed* George Murphy, PhD
Hematology & Medical Oncology, BUSM
Pluripotent Stem Cell Modeling of Human Disease
(Host: Andy Zoeller)
4/22/14 Wendy L. Picking, PhD
Microbiology and Molecular Genetics, Oklahoma State University
No child should die from it: Toward a vaccine to prevent shigellosis
(Host: Esther Bullitt)

Additional Boston area seminars

Fall 2013

Department of Physiology & Biophysics Seminar Series

Tuesdays 1:30, Room R103

Date Speaker Title & Host
9/3/13 Willy Wriggers, PhD
D.E. Shaw Research
From Atoms to Living Organisms: Emergent Complexity of Multiscale Computational
Modeling
(Host: David Atkinson)
9/17/13 Hyesung Jeon, PhD
Harvard Medical School
Molecular imaging and functional studies of EGFR pathway in cancer cells
(Host: Graham Shipley)
10/1/13 Chris Akey, PhD
Physiology & Biophysics – BUSM
Structure of the SecY channel at an early stage of protein translocation
10/22/13 Michael Regnier, PhD
University of Washington
Mechanistic and translational studies of striated muscle contraction
(Host: Bill Lehman)
10/29/13 Jeremiah Farelli, PhD
Chemistry, Boston University
Panoramic functional view of the Haloalkanoic Acid Dehalogenase superfamily using a
sparse sampling high-throughput approach.”
(Host: Chris Akey)
11/5/13 Jeff Miller, PhD
Neurology, BUSM
Molecular Pathogenesis of Muscular Dystrophies
(Host: David Atkinson)
11/12/13 Steen Hansen, PhD
Boston Children’s Hospital
Rho signaling in epithelial cell growth and cell death
(Host: Lynne Coluccio)
12/3/13 David Harris, PhD
Biochemistry, BUSM
The Prion Protein: A Dual Role in Prion and Alzheimer’s Diseases
(Host: David Atkinson)
12/10/13 Michael Eck, PhD
Dana Farber Cancer Institute
Structural approaches to understanding and targeting EGFR mutations in Lung Cancer
(Host: Esther Bullitt)
1/14/13 John Samuelson, PhD
Goldman School of Dental Medicine
The low-hanging fruit of cyst and oocyst walls: strategies to discover the structural
components of the walls of parasitic protists
(Host: Esther Bullitt)

Additional Boston area seminars

Spring 2013

Department of Physiology & Biophysics Seminar Series

Tuesdays 1:30, Room R103

Date Speaker Title & Host
1/10/13*Special Seminar: Thursday in Rm. R-115 Lynne M. Coluccio, PhD
Boston Biomedical Research Institute
Mammalian class I myosins: Myo1c in adaptation in the inner ear and cell-cell contact
(Host: Andy Zoeller)
1/22/13 Celia Schiffer, PhD
University of Massachusetts Medical School
Combating Drug Resistance: Lessons from the Viral Proteases of HIV-1 and HCV
(Host: Olga Gursky)
1/29/13 Stefan Raunser, PhD
Max Planck Institute of Molecular Physiology
A Structural Biologist Looks at Molecular Life and Death of a Bug
(Host: Bill Lehman)
2/19/13 Robert Griffin, PhD
Massachusetts Institute of Technology
High Resolution Studies of Amyloid Fibrils
(Host: Graham Shipley)
2/26/13 Mikel Garcia-Marcos, PhD
Boston University School of Medicine
Discovering Novel G Protein Signaling Circuits: Implications in Cancer Metastasis
(Host: David Atkinson)
3/12/13 Melissa Moore, PhD
University of Massachusetts Medical School
Structure and Dynamics of Uber Complex RNPs
(Host: Assen Marintchev)
3/19/13 Daniel Oprian, PhD
Brandeis University
Structure and Mechanism of Proteins from the Rod Cell Phototransduction Cascade
(Host: Carter Cornwall)
4/2/13 James Rothman, PhD
Yale University School of Medicine
The Mechanism of Membrane Fusion and its Regulation for Quantal Synaptic Transmission
(Host: Graham Shipley/David Harris)
4/9/13 Maureen Estevez, PhD
Brown University
A Visual System in Vestibular Coordinates: The role of ON-type Direction-Selective Retinal Ganglion Cells in Retina and Brain
(Host: Carter Cornwall)
4.23/13 Jorge Haller, PhD
Massachusetts General Hospital
Role of the ABCA12 Lipid Transporter in Skin Ceramide Biosynthesis
(Host: Andy Zoeller)
5/14/13 David Stokes, PhD
Skirball Institute
A novel conformational change drives the alternating access mechanism for Zn2+ transport by YiiP
(Host: Esther Bullitt)

Additional Boston area seminars

Fall 2012

Department of Physiology & Biophysics Seminar Series

Tuesdays 1:15, Room R103

Date Speaker Title & Host
9/25/12 Nikolaus Grigorieff, PhD
Brandeis University
Restoring high-resolution contrast in images affected by beam-induced motion
(Host: Chris Akey)
10/9/12 John Condeelis, PhD
Albert Einstein College of Medicine
Mechanism-based insights into prognosis and treatment of breast cancer derived from high resolution multiphoton imaging
(Host: Bill Lehman)
10/23/12 Michael Reedy, PhD
Duke University
Time-Resolved Molecular Dynamics of Stretch Activation, Length-Dependent Activation and Force Generation in Insect Flight Muscle and Mammalian Heart
(Host: Bill Lehman)
11/13/12 John Hartwig, PhD
Harvard Medical School
The Filamins, organizers of cell structure, mechanics and function
(Host: Bill Lehman)
11/20/12 Tim Gardner, PhD
Boston University, Biology Dept.
Neural circuits and their development: vocal learning in songbirds
(Host: Chris Gabel)
11/27/12 Wolfgang Peti, PhD
Brown University
Structural mechanics and function of large protein signaling complexes
(Host: Assen Marintchev)
12/4/12 Michael Previs, PhD
University of Vermont
The molecular mechanics of cardiac myosin-binding Protein C in the modulation
of cardiac contractility

(Host: Jeff Moore/Bill Lehman)
12/11/12 Adam Cohen, PhD
Harvard University
Optical electrophysiology with microbial rhodopsins
(Host: Chris Gabel)
12/18/12
*To be held in Kiefer Auditorium*
Jack Szostak, PhD TBA
(Host: James Hamilton)

Additional Boston area seminars

Spring 2012

Department of Physiology & Biophysics Seminar Series

Tuesdays 1:15, Room R115

Date Speaker Title & Host
1/17/12 Didem Vardar, PhD
Wellesly College
It is all in the details: Probing Notch regulation one amino acid at a time
(Host: Jamie McKnight)
1/24/12 Allen Ehrlicher, PhD
Harvard University
Molecular Mechanotransduction: How forces trigger cytoskeletal dynamics
(Host: Jeff Moore)
1/31/12 David Weitz, PhD
Harvard University
Fluctuations and Dynamics arrest in cells
(Host: Bill Lehman)
2/21/12 Bert Van Den Berg, PhD
U Mass Medical School
Outer membrane uptake channels for small molecules in Pseudomonas aeruginosa : Why so many?
(Host: Chris Akey)
3/6/12 Ty Chang, PhD
Dartmouth Medical School
Cellular cholesterol esterification in atherosclerosis and neurodegenerative diseases
(Host: Andy Zoeller)
3/13/12 Nurit Haspel, PhD
U Mass Boston
Conformational exploration and self-assembly of protein molecules
(Host: Barbara Seaton)
3/20/12 No Seminar

3/27/12 Sandor Vajda, PhD
Boston University
TBA
(Host: Barbara Seaton)
4/24/12 Douglas Golenbock, PhD
UMass Medical School
TBA
(Host: Andy Zoeller)
5/15/12 Athar Chishti, PhD
Tufts University School of Medicine
Regulation of Cell Polarity
(Host: Jamie McKnight)

Additional Boston area seminars

Fall 2011

Department of Physiology & Biophysics Seminar Series

Tuesdays 1:15, Room R103

Date Speaker Title & Host
9/13/11 Rahm Gummuluru, PhD
BU School of Medicine
Parasitization of Dendritic Cell Functions by HIV
(Host: Andy Zoeller)
9/27/11 Roberto Dominguez, PhD
University of Penn School of Medicine
Structure-Function of Actin Filament Assembly
(Host: Bill Lehman)
10/4/11 Natalia Beglova, PhD
Harvard Medical School
On the way to understanding molecular mechanisms of antiphospholipid syndrome
(Host: Olga Gursky)
10/11/11 Zemin Yao, PhD
University of Ottawa
New insights into structure/function relationship within human apoB
(Host: Jamie McKnight)
10/18/11 Dan Kirschner, PhD
Boston College
Nerve Myelin: A New Rap On An Old Wrap – Pushing the Boundaries of Analysis
(Host: Esther Bullitt)
10/25/11 David W. Christianson
University of Pennsylvania
Evolutionary Divergence of Structure and Function in Arginase, Histone Deacetylase, and Polyamine Deacetylase
(Host: Barbara Seaton)
11/1/11 Bob Murphy, PhD
University of Colorado
TBA
(Host: Andy Zoeller)
11/8/11 David Berson, PhD
Brown University
TBA
(Host: Carter Cornwall)
11/15/11 John Engen, PhD
Northeastern University
Hydrogen exchange mass spectrometry to probe the conformation of proteins both in solution and in membranes
(Host: Esther Bullitt)
12/6/11 Jim Baleja, PhD
Tufts University School of Medicine
Structure and Function of EH domain Interactions in Endocytosis and Cell Signaling
(Host: Barbara Seaton)
12/14/11
in rm. L301
Peter Gunning, PhD
University of New South Wales
Tropomyosin diversifies actin cytoskeleton function in time and space and is a new target for chemotherapy
(Host: Bill Lehman)

Additional Boston area seminars

Spring 2011

Department of Physiology & Biophysics Seminar Series

Tuesdays 1:15, Room R115

Date Speaker Title & Host
1/4/11 No Seminar
1/11/11 Suzanne Walker, PhD
Harvard Medical School
Structure and Inhibition of Human O-GlcNAc transferase
(Host: Jamie McKnight)
1/18/11 Charles Serhan, PhD
Brigham and Women’s Hospital
Functional Metabolomics Uncover Novel Lipid Mediators in Resolving Inflammatory Exudates

(Host: Donald M. Small)
1/25/11 Peter B. Moore, PhD
Yale University
Conformational Contributions to Antibiotic Resistance: Lessons Learned from the Ribosome
(Host: Graham Shipley)
2/1/11 Gerhard Wagner, PhD
Harvard University
NMR studies of membrane proteins

(Host: Assen Marintchev)
2/8/11 No Seminar
2/15/11 Frank McCormack, MD
University of Cincinnati
Antimicrobial Functions of the Pulmonary Collectins
(Host: Barbara Seaton)
2/22/11 Michael H. A. Roehrl, MD, PhD Patholgy of Cancer
(Host: Assen Marintchev)
3/1/11 David Berson, PhD
Brown University
TBA
(Host: Carter Cornwall)
3/8/11 No Seminar

3/15/11 John D. Gross, PhD
UCSF
Insights into the structure, activity and control of HIV Vif
(Host: Assen Marintchev)
3/22/11 Tatyana Svitkina, PhD
University of Pennsylvania
Roles of Non-Muscle Myosin II in Protrusion, Adhesion and Contraction
(Host: Bill Lehman)
3/29/11 Shujun Yuan, PhD
Boston University
Structure and function of the apopt
(Host: Christopher Akey)
4/5/11 Corey Wilson, PhD
Yale University
Assembling a Molecular Switch: Reconciling Protein Folding And Design of a Complex System

(Host: Jamie McKnight)
4/12/11 Daniel Rossignol, PhD
Eisai Product Creation Systems
In vitro, in vivo and clinical development of a Toll-like receptor-4 antagonist
(Host: Graduate Students)
4/19/11 Albert Wang, PhD
BBRI
Actin Dynamics and Its Regulation by Caldesmon
(Host: Bill Lehman)
4/26/11 Michael Welte, PhD
University of Rochester
Fat, flies and videotape: Dynamic lipid droplets in Drosophila embryos
(Host: Donald M. Small)
5/3/11 Xinchao Yu, PhD
Research Fellow, Howard Hughes Medical Institute and the Structural Biology Program
Sloan-Kettering Institute
Functional and Structural Studies of the Complex Between Coatomer and Arfl

(Host: Chris Akey)
5/10/11 Michael Rynkiewicz, PhD
Boston University School of Medicine
Department of Physiology & Biophysics
Mechanisms of Interaction Between Surfactant Protein-D and Influenza A Virus Hemagglutinin

(Host: Jim Head)
5/17/11 Jonathan Soboloff, PhD
Temple University School of Medicine
Assistant Professor, Dept. of Biochemistry
Fels institute for Cancer Research and Molecular Biology
Mechanisms Regulating STIM Expression and Function in Ca² Signaling
(Host: R. Andrew Zoeller)

Additional Boston area seminars

Fall 2010

Department of Physiology & Biophysics Seminar Series

Tuesdays 1:15, Room R103

Date Speaker Title & Host
9/28/10 Christopher Fang-Yen, PhD
Harvard University, Department of Physics
Optical dissection of behavior in C. elegans (Host: Christopher Gabel)
10/05/10 No Seminar
10/12/10 Karen Allen, PhD
CAS, Dept of Chemistry
Boston University
Uncovering new functions in a super family of phosphatases

(Host: Carter Cornwall)
10/19/10 No Seminar
10/26/10 Deborah Perlstein, PhD
Boston University, CAS Chemistry
Microbe, Microbe, toxic microbe, How does your cell wall grow?

(Host: Bill Lehman)
11/2/10 Thomas Charles Pochapsky, PhD
Brandeis University
Department of Chemistry
Are you my substrate? NMR insights into enzyme-substrate interactions
(Host: Barbara Seaton)
11/9/10 Jim Hogle, PhD
Harvard Medical School
BU School of Medicine, Department of Biology
TBA
(Host: Barbara Seaton)
11/16/10 Carlos Fernandez-Hernando, PhD
NY University School of Medicine
miR-33 as a Therapeutic target for metabolic syndrome?
(Host: Donald Small)
11/23/10 No Seminar

11/30/10 Rosalie K. Crouch, PhD
Medical University of South Carolina
Opthalmology
TBA
(Host: Carter Cornwall)
12/7/10 Dagmar Ringe, PhD
Brandeis University
Departments of Biochemistry and Chemistry
TBA
(Host: Barbara Seaton)
12/14/10 No Seminar
12/21/10 No Seminar

Additional Boston area seminars

Spring 2010

Department of Physiology & Biophysics Seminar Series

1:00-2:20pm
Rm R115
Last update 7 January 2010

Date Speaker Title & Host
1/19/10 Samara Reck-Peterson, PhD
Harvard University, Department of Cell Biology
Walking Mechanism of Cytoplasmic Dynein
(Host: Dr. Bill Lehman)
1/26/10 Andres Leschziner, PhD
Harvard University, Department of Molecular and Cellular Biology
Structural studies of ATP-dependent chromatin remodeling
(Host: Dr. Christopher Akey)
2/09/10 John Straub, PhD
Dept of Chemistry
Boston University
Exploring the role of sequence and environment in the early stages of the protein aggregation pathway
(Host: Dr. Barbara Seaton)
4/6/10 Vladimir Kefalov, PhD
Dept Ophthalmology and Visual Sciences Washington University School of Medicine
Cone visual cycle in the vertebrate retina?
(Host: Dr. Carter Cornwall)

Additional Boston area seminars

Fall 2009

Department of Physiology & Biophysics Seminar Series

1:00-2:20pm,
Rm L301

Last update 24 August 2009

Date Speaker Title & Host
09/29/09 John Straub, PhD
Dept of Chemistry, Theoretical & Computational Chemistry & Biophysics
BU
TBA
(Host: Dr. Barbara Seaton)
10/13/09 Donald M. Engelman, PhD
Dept of Molecular Biology and Biophysics
Yale University
TBA
(Host: Dr. Graham Shipley)
10/20/09 Reid Gilmore, PhD
Dept of Biochemistry and Molecular Pharmacology
UMass Medical School
TBA
(Host: Dr. Christopher Akey)
10/27/09 Michael C. Phillips, PhD
Dept of Pediatrics
UPenn
TBA
(Host: Dr. Donald M. Small)
11/03/09 Douglas M. Swank, PhD
Dept of Biology
RPI
TBA
(Host: Dr. Jeff Moore)
11/10/09 Uwe Beffert, PhD
Dept of Biology
BUSM
TBA
(Host: Dr. Donald M. Small)
11/17/09 Osamu Shimomura, PhD
BUSM Professor Emeritus
Special Seminar
3pm in the 670 Albany St. Auditorium
12/15/09 Bruce Furie, MD, PhDBIDMC
Harvard University
TBA
(Host: Dr. Barbara Seaton)

Additional Boston area seminars

Spring 2009

Department of Physiology & Biophysics Seminar Series

1:00-2:20pm,
NEW ROOM: 670 Albany St, Rm 107/108

Last update 5 February 2009
Please contact Dr. Haya Herscovitz (haya@bu.edu) with any questions.

Date Speaker Title & Host
01/13/09 Monte Krieger, Ph.D.
Dept. of Biology
MIT
Charting the Fate of the ‘Good Cholesterol’ – Characterization of the HDL receptor SR-BI and its influence on Coronary Heart Disease
01/20/09 Dawn Braseamle, Ph.D.
Dept. of Nutritional Sciences
Rutgers University
Lipid Droplet-Associated Proteins Control Triacylglycerol Metabolism
02/03/09 Mary Roberts, Ph.D.
Merkert Chemistry Center
Boston College
Akt and PTEN: the yin and yang of signaling
02/10/09 Jane Kondev, Ph.D.
Dept. of Physics
Brandeis Univ.
Geography of bacterial chromosomes
02/17/09 Sunney Xiaoliang Xie, Ph.D.
Dept. of Chemistry & Chem. Biol.
Harvard Univ.
Holding Life Processes up to the Light, at the Single-Molecule Level
2/24/09 Lila Geirasch, Ph.D.Dept. of Biochem & Mol Biol, Dept of Chem
U Mass, Amherst
(Host: Dr. James McKnight)
FRIDAY
02/27/09
Alexey Ladokhin, Ph.D.
Dept. Biochem. & Mol. Biol.
Kansas Univ. Medical Center
Thermodynamics of pH-Triggered Membrane Protein Insertion: what can we learn about membrane protein stability?
(Host: Dr. Olga Gursky)
03/10/09 Adam Lerner, Ph.D.
Dept. Medicine & Pathology
Director, Hematology Training Pgm
Boston Univ. School of Medicine
Mechanistic studies of the anti-estrogen resistance gene AND-34/BCAR3
03/17/09 Lee Makowski, Ph.D.
Div. of Biological Sciences
Argonne National Lab
Linking the Protein Ensemble to Function
03/31/09 John Clardy, Ph.D.
Department of Biological Chemistry & Molecular Pharmacology
Harvard Medical School
What We Can Learn from Bugs
04/07/09 Stanley Hazen, Ph.D.
Dept. of Mol. Med.
Cleveland Clinic, Lerner College of Medicine
Case Western Reserve Univ.
Myloperoxidase, HDL and PON1 – functional partners in atherosclerosis (Host: Dr. Donald M. Small)
FRIDAY
04/17/09
9a-4:15p
Rm R115
STUDENT SEMINAR DAY
Graduate Student Talks
FRIDAY
04/24/09
9a-4:15p
Rm R115
STUDENT SEMINAR DAY
Graduate Student Talks
04/28/09 Dr. Mason W. Freeman
Lipid Metabolism Unit
Dept. of Medicine
Mass General Hospital / Harvard Medical School
ABCA Transporters: Lipid Movers and Shakers (Host: Dr. David Atkinson)
05/05/09 Dr. Jim Delikatny
Assistant Director, Molecular Imaging Laboratory
Research Associate Professor, Dept. of Radiology
University of Pennsylvania
Probing lipid metabolism non-invasively with MR and optical imaging (Host: Dr. David Atkinson)
06/16/09 Dr. Charles Sindelar
Staff Scientist
Dept. of Biochemistry
Brandeis University
A ‘catalytic engine’ that accounts for kinesin motility and directionality
(Host: Dr. William Lehman)

Fall 2008

Department of Physiology & Biophysics Seminar Series

1:00-2:20pm, room L301

Last update 12/04/2008
You may contact Dr. Haya Herscovitz (haya@bu.edu), the fall seminar coordinator, with any questions.

Date Speaker Title & Host
9/2/08 Christopher Gabel, PhDHarvard University, Dept. Of Physics
Dept. of Physiology & Biophysics
“The Study of Neural Regeneration in C. Elegans Using Femtosecond Laser Surgery” (Host: Dr. Andy Zoeller)
9/9/08 Alexei Kurakin, PhDBeth Israel Deaconess HospitalMedical Center “Adaptice plasticity in protein interactions and cellular organization”
(Host: Dr. Andy Zoeller)
9/19/08Friday Hanna Rapaport, PhDBen-Gurion University of NegevDept. Biotechnology Engineering “Structure of Amphiphilic Peptides at Interfaces” (Host: Dr. Donald M. Small)
9/23/08 Rajesh Ramachandran, PhDThe Scripps Research InstituteDept. Cell Biology - NEW Date! Fluorescence-detected dynamics of dynamin-membrane interactions inclathrin-mediated endocytosis (Host: Dr. Andy Zoeller)
10/07/08 Kenneth Walsh, PhD,BU School of Medicine,
Whitaker Cardiovascular Institute
TBA (Host: Dr. William Lehman)
10/21/08 Laura Liscum, PhDTufts School of Medicine, Dept. Physiology TBA (Host: Haya Herscovitz and Barbara Schrieber)
10/28/08 Richard Cohen, PhDBU School of Medicine, Vascular Biology Oxidative post-translational modification of proteins and cellular function (Host: Dr. Haya Herscovitz)
11/04/08 Matt Lang,Ph.D.MIT Advances in Single Molecule Biophysics, Studies of Actin Machinery and the Force Generation Mechanism of Kinesin (Host: Dr. Haya Herscovitz and Michael Greenberg)
12/02/08 Alan Engelman, Ph.D.Dept. of Pathology
Harvard Medical School
Integrase-Binding Co-factors and HIV-1 Infection
12/09/08 Charles Brenner, Ph.D.Depts. of Genetics & Biochemistry & the Norris Cotton Cancer CenterDartmouth Medical School TBA
12/16/08 Lila Geirasch, Ph.D.
Dept. of Biochem & Mol Biol, Dept of Chem U Mass, Amherst
POSTPONED due to weather (Host: Dr. James McKnight)

Spring 2008

Department of Physiology & Biophysics Seminar Series

1:00-2:20pm, room L301

Date Speaker Title & Host
1/15/08 Dr. Karen AllenBoston University School of MedicineDept. of Physiology & Biophysics “Structural Enzymology”
1/22/08 Dr. Biju PillaiBoston University School of Medicine
Dept. of Physiology & Biophysics
“How fast do very long chain saturated fatty acids flip and flop?” (Host: Hamilton lab)
1/29/08 Dr. Krishna MurthyUniversity of Alabama at Birmingham “Structure of ApoA-1” (Hosts: D. Atkinson, D. Small and G. Shipley)
2/12/08 Dr. Jonathan GoldbergMemorial Sloan-Kettering
Cancer Center, New York
“Structure and Function of COPII Transport Vesicles” (Hosts: G. Shipley, C. Akey)
2/26/08 Dr. M. Elizabeth StroupeBrandeis University “Structural studies of splicing complexes”(Host: E. Bullitt)
3/04/08 Dr. Barry Honig
Center for Computational Biology and BioinformaticsColumbia University, New York
“Relating Cellular to Molecular Specificity”(Hosts: D. Small/D. Atkinson)
3/11/08 Dr. David RonSkirball Institute,
New York University Medical Center
“Physiological considerations in unfolded protein responses” (Host: H. Herscovitz)
3/18/08 Dr. Rex F. Pratt, Ph.D.Professor of Biochemistryand Beach Professor of ChemistryWesleyan University “Enzyme mechanisms” (Host: K. Allen)
3/25/08 Hwai-Chen Guo, Ph.D.BUSM Glycosylasparaginase cis- to trans-hydrolysis of amide bonds
4/08/08 Dr. Martin KarplusHarvard University,Department of Chemistryand Chemical Biology “How Proteins Work: Insights from Simulations” (Host: B. Lehman)
4/18/08 & 4/25/08 Student Seminar Days (Hosts: Drs. C. Akey, K. Allen)
4/29/08 Dr. Ramanujan HegdeCell Biology and Metabolism Branch
National Institute of Child Health and Human development (NIH)Bethesda, MD 20892
“The biosynthesis of secretory and membrane proteins” (Host: C. Akey)
5/06/08 Dr. Guangwei DuSUNY, Stonybrook (NY)Center for Developmental Genetics
Dept. of Pharmacology
“Lipid signal regulation of membrane trafficking and oncogenesis” (Host: R.A. Zoeller)
Friday,
5/09/083:00pmRoom L303
Seemantini Nadkarni, PhDHarvard Medical School
Massachusetts General HospitalWellman Center for Photomedicine
“Optical Techniques to Evaluate Atherosclerosis: a Multi-factorial Perspective” (Host: R.A. Zoeller)
5/13/08 Dr. Mary MunsonUMass Medical Center “The Exocyst Complex: Molecular Architecture and Function in Exocytosis”
(Host: CJ McKnight)
5/20/08 Norman A. Mazer, M.D., PhD
Boston University School of Medicine
“A Physiologically-Based Mathematical Model of the Metabolic Clearance Rate of Testosterone” (Host: D. Atkinson)

Fall 2007

Department of Physiology & Biophysics Seminar Series

1:00-2:20pm, room L301

Date Speaker Title & Host
9/18/07 Dr. Nicholas R. SilvaggiBoston University School of MedicineDept. of Physiology & Biophysics Structural Insights into Inhibition of the Clostridium botulinum Neurotoxin Serotype A Light Chain”
(Host: Allen lab)
9/25/07 Dr. David Cane, Professor
Brown University Department of Chemistry
“Nature’s Dirty Secrets” (Host: K. Allen)
10/09/07 Dr. Alexey OnufrievAssistant ProfessorDepartments of Computer Science and Physics, Virginia Tech “Dynamics” (Host: B. Lehman)
10/16/07 Dr. Tom CroninUniversity of Maryland at Baltimore County in the Department of Biology “Color Madness: The Evolution of Color and Polarization Vision in Mantis Shrimps”(Host: C. Cornwall)
10/23/07 Dr. Jay NeitzDepartment of Cell Biology, Neurobiology & Anatomy
Medical College of Wisconsin
“Evolutionary endgame for the eye” or “Welcome to the wonderful world of color: gene therapy for colorblindness in a primate” (Host: C. Cornwall)
11/06/07 Dr. William BachovchinTufts University
Biochemistry Department
Are enzymes templates or mechanical devices?” (Host: J. Hamilton)
11/13/07 Dr. Michael RadermacherHealth Science Research Facility
Univ of Vermont Medical School
“The Structure of Complex I in the Mitochondrial Respiratory Chain” (Host: C Akey)
11/27/07 Preethi ChandramouliBoston University School of MedicineDept. of Physiology & Biophysics “Structure of the 80S ribosome”
(Host: Akey lab)
12/04/07 Dr. Ernst J. Schaefer, MD
Director, Cardiovascular Research & Lipid Metabolism Laboratories & Lipid and Heart Disease Prevention Program Tufts University School of Medicine Friedman School of Nutrition Science & Policy
“The Metabolism of High Density Lipoprotein Particles”(Host: J. Hamilton)
12/18/07 Dr. Jeff HochDepartment of Molecular, Microbial, and Structural BiologyUniversity of Connecticut Health Center “Folding, Stability, and Structure of Human Prolactin” (Host: CJ. McKnight)
<!–[if gte mso 9]> Normal 0 false false false EN-US X-NONE X-NONE MicrosoftInternetExplorer4 <![endif]–><!–[if gte mso 9]> <![endif]–> <!–[endif]–>Dr. Christopher Fang-Yen
Directory|BUMC
April 1, 2014
Primary teaching affiliate
of BU School of Medicine