Thomas A. Einhorn, MD, Professor and Chairman

Professor and Chairman

Thomas A. Einhorn, M.D. is Chairman of the Department of Orthopaedic Surgery and Professor of Orthopaedic Surgery, Biochemistry and Biomedical Engineering at Boston University.  A graduate of Rutgers University and Cornell Medical College, he completed his internship at the Hospital of the University of Pennsylvania, orthopaedic residency at St. Luke’s – Roosevelt Hospital in New York City, and a fellowship at the Hospital for Special Surgery.  His professional interests include research on the repair and regeneration of bone and cartilage, reconstructive surgery of the hip and knee, and the treatment of metabolic bone disease. 

Dr. Einhorn has served as Chairman of the Orthopaedics and Musculoskeletal Study Section of the National Institutes of Health, President of the Orthopaedic Research Society, President of the International Society for Fracture Repair and Chairman of both the Committee on Examinations and the Council on Research and Scientific Affairs of the American Academy of Orthopaedic Surgeons.  Currently, he serves on the Board of Trustees of the Orthopaedic Research and Education Foundation and the National Osteoporosis Foundation. 

His awards include the Marshall R. Urist Award and the Alfred R. Shands, Jr. Award from the Orthopaedic Research Society, the Kappa Delta Award from the American Academy of Orthopaedic Surgeons, the Dr. Marian Ropes Physician Achievement Award from the Arthritis Foundation and the Marshall Schiff Award from the American College of Rheumatology.  He is Deputy Editor for Current Concepts Reviews for The Journal of Bone and Joint Surgery, and serves on the Editorial Boards of The Journal of Bone and Mineral Research, Journal of Orthopaedic Research and Bone. Since 1997, he has been listed in Best Doctors. An author of over 165 peer-reviewed articles, his career goals are dedicated to exploring the role of molecular medicine in orthopaedic surgery.

Specialty
Hip and Knee Replacement Surgery

Office Address
Boston University Orthopaedic Surgical Associates
725 Albany St.
Shapiro 4th Floor, Suite 4B
Boston, MA  02118

Phone 617-638-8435
Fax: 617-638-8493
Email: thomas.einhorn@bmc.org

Patient Appointments/Referrals
Please call 617-638-5633 to schedule an appointment.

Medical School and Graduation Year
Cornell University Medical College, New York, New York MD, 1976

Residency, Specialty, and Graduation Year
July 1, 1978 – June 30, 1981
Resident, Orthopaedic Surgery
St. Luke’s Roosevelt Hospital Center, College of Physicians and Surgeons New York, New York

March 1, 1980 – June 30, 1980
Resident, Pediatric Orthopaedics
Alfred I. duPont Institute
Wilmington, Delaware

July 1, 1977 – June 30, 1978
Resident, General Surgery
St. Vincent’s Hospital and Medical Center
New York, New York

Residency Fellowship, Specialty, and Graduation Year
July 1, 1981 – June 30, 1982
Fellow, Metabolic Bone Disease and Orthopaedic Research
The Hospital for Special Surgery
New York, New York

Board Certification, Year Received
National Board of Medical Examiners
July 1, 1977
American Board of Orthopaedic Surgery
July 27, 1984
Recertification – July 25, 1997 

Research Interests
The Biology of Skeletal Repair and Regeneration

Clinical Interests
Hip and Knee Replacement and Reconstructive Surgery
Treatment of Avascular Necrosis (Osteonecrosis) of the Hip and Knee

Awards
Alfred R. Shands, Jr., M.D. Award (Orthopaedic Research Society and American Orthopaedic Association), 2008

Dr. Marian Ropes – Physician Achievement Award (Arthritis Foundation ), 2006

Marshall Schiff Award (American College of Rheumatology), 2000

Kappa Delta Award,  (American Academy of Orthopaedic Surgeons), 1999

Listed in “The Best Doctors in America” 1997-present

ABC (American British Canadian) Traveling Fellowship, 1989 (American Orthopaedic Association)
M.R. Urist Award, 1997

Scientific Articles
Gerstenfeld, L. C., Thiede, M., Seibert, K., Mielke, C., Phippard, D., Svagr, B., Cullinane, D. and Einhorn, T. A.: Differential Inhibition of Fracture Healing by Non-Selective and Cyclooxygenase-2 Selective Non-Steroidal Anti-Inflammatory Drugs. J. ORTHOP. RES. 21:670-675, 2003.

Bhattacharyya, T., Tornetta, P., Healy, W. L., and Einhorn, T. A.: The Validity of Supporting Data for Claims Made in Orthopaedic Print Advertisements. J. BONE JOINT SURG. 85A:1224-1228, 2003.

Einhorn, T. A., Majeska, R. J., Mohaideen, A., Kagel, E. M., Bouxsein, M. L., Turek, T. J. and Wozney, J. M.: A Single Percutaneous Injection of Recombinant Human Bone Morphogenetic Protein-2 Accelerates Fracture Repair. J. BONE JOINT SURG. 85A:1425-1435, 2003.

Einhorn, T. A.: Clinical Applications of Recombinant Human BMPs: Early Experience and Future Development. J. BONE JOINT SURG. 85A(Suppl. 3):82-88, 2003.

Gerstenfeld, L.C., Cho, T-J., Kon, T., Aizawa, T., Tsay, A., Barnes, G. L., Graves, D. T., and Einhorn, T. A.: Impaired Fracture Healing in the Absence of Tumor Necrosis Factor-Ą Signaling: The Role of TNF-a in Endochondral Cartilage Resorption. J. BONE MINER. RES., 18:1584-1592, 2003.

Shea, C. M., Edgar, C. M., Einhorn, T. A., and Gerstenfeld, L. C.: BMP Treatment of C3H10T1/2 Mesenchymal Stem Cells Induces Both Chondrogenesis and Osteogenesis. J. CELL BIOCHEM, 15:1112-1127, 2003.

Pacicca, D. M., Patel, N., Lee, C., Salisbury, K., Lehman, W., Carvalho, R., Gerstenfeld, L.C., and Einhorn, T. A.: Expression of Angiogenic Factors during Distraction Osteogenesis. BONE, 33:889-898, 2003.

Schmidmaier, G., Wildemann, B., Melis, B., Krummrey, G., Einhorn, T. A., Haas, N. P. And Raschke, M.: Development and Characterization of a Standard Closed Tibial Fracture Model in the Rat. EUR. J. TRAUMA, 30:35-42, 2004.

Gerstenfeld, L. C. and Einhorn, T. A.: COX Inhibitors and Their Effects on Bone Healing. EXPERT OPIN. DRUG SAF., 2:131-136, 2004.

Nakazawa, T., Nakajima, A., Seki, N., Okawa, A., Kato, M., Moriya, H., Amizuka, N., Einhorn, T.A. and Yamazaki, M.: Gene Expression of Periostin in the Early Stage of Fracture Healing Detected by cDNA Microarray Analysis. J. ORTHOP. RES., 22:520-525, 2004.

Carvalho, R. S., Einhorn, T. A., Lehman, W., Edgar, C., Alyamani, A., Apazidis, A., Pacicca, D., Clemens, T. L., and Gerstenfeld, L. C.: The Role of Angiogenesis in a Murine Model of Distraction Osteogenesis. BONE 34:849-861, 2004.

Barnes, G. L., Hebert, K., Kamal, M., Javed, A., Einhorn, T. A., Lian, J.B., Stein, G. S., and Gerstenfeld, L. C.: Fidelity of Runx2 Activity in Breast Cancer Cells is Required for the Generation of Metastases Associated Osteolytic Disease. CANCER RES., 64:4506-4513, 2004.

Bhandari, M., Swiontkowski, M., Einhorn, T. A., Tornetta III, P., Schemitsch, E., and Wright, J., G.: Inter-observer Agreement in the Application of the Levels of Evidence to Scientific Papers in The Journal of Bone and Joint Surgery. J. BONE JOINT SURG., 86A:1717-1720, 2004.

Lochner, H. V. and Einhorn, T. A. : Advances in Therapeutic Diagnostics: Hormone Replacement Therapy. J. AMER. ACAD. ORTHOP. SURG., 12:291-294, 2004.

Kim, H. J. W., Bian, H., Randall, T., Garces, A., Gerstenfeld, L. C., and Einhorn, T. A.: Increased VEGF Expression in the Epiphyseal Cartilage Following Ischemic Necrosis of the Capital Femoral Epiphysis. J. BONE MINER. RES., 19:2041-2048, 2004.

Lehmann, W., Schinke, T., Catala-Lehnen, P., Gebauer, M., Pogoda, P., Gerstenfeld, L.C., Rueger, J.M., Einhorn, T. A., and Amling, M.: Absence of Mouse Pleiotrophin Does Not Affect Bone Formation In Vivo. BONE, 35:1247-1255, 2004.

Mont, M. A., Ragland, P. S., Biggins, B., Friedlaender, G., Patel, T., Cook, S., Etienne, G., Shimmin, A., Kildey, R., Rueger, D.C., and Einhorn, T. A.: Use of Bone Morphogenetic Proteins for Musculoskeletal Applications: An Overview. J. BONE JOINT SURG., 86A:S2:41-55, 2004.

Bhandari, M., Bajammal, S., Guyatt, G. H., Griffith, L., Busse, J., W., Schunermann, H., and Einhorn, T., A.:The Effect of Bisphosphonates on Periprosthetic Bone Mineral Density After Total Joint Arthroplasty. A Meta-Analysis. J. BONE JOINT SURG., 87A:293-301, 2005.

Lehmann, W., Edgar, C. M., Wang, K., Cho, T-J., Barnes, G. L., Kakar, S., Graves, D. T., Rueger, J. M., Gerstenfeld, L. C., and Einhorn, T. A.: Tumor Necrosis Factor Alpha (TNF-Ą) Coordinately Regulates the Expression of Specific Matrix Metalloproteinases (MMPs) and Angiogenic Factors During Fracture Healing. BONE, 36:300-310, 2005.

Textbooks
Orthopaedic Basic Science: The Biology and Biomechanics of the Musculoskeletal System. 2nd Edition. J.A. Buckwalter, T.A. Einhorn, and S.R. Simon, Eds., Rosemont, Illinois, AM. ACAD. ORTHOP. SURG., 2000.

Orthopaedic Surgery Essentials: P. Tornetta, III and T. A. Einhorn, Series Eds., Philadelphia, PA., LIPPINCOTT WILLIAMS & WILKINS, 2003.

Bone Tissue Engineering: J. O. Hollinger, T. A. Einhorn, B. Doll and C. Sfeir Eds., Boca Raton, Fla. CRC Press, 2004.

Primary teaching affiliate
of BU School of Medicine