Sassan Falsafi MD
Sassan Falsafi, MD, MS ChE
PGY5

Resident (7/2002-6/2004)
Department of Otolaryngology – Head & Neck Surgery
Boston Medical Center
Boston, MA
Education/Training
Otolaryngology Resident (7/2000-6/2002)
Department of Otolaryngology – Head & Neck Surgery, SUNY–Buffalo, Buffalo, NY
Surgical Intern (6/99-6/00)
Stanford University Medical Center Stanford, CA
MD
Indiana University School of Medicine (5/98)
MS Chemical Engineering
University of California, Davis (5/88)
Thesis: Flow Visualization of Superposed Flows: Study of Interfacial Shape and Stability
Advisor: Professor Brian G. Higgins, Ph.D.
B.S. Chemical Engineering
University of California, Berkeley (12/84)
Research
Post Doctoral Research Fellow ( 6/1/98 – 6/1/99)
Biomaterials Development & Tissue Engineering Laboratory
Division of Otolaryngology – Head & Neck Surgery, R-135
Stanford University Medical Center, Stanford, California 94305-5328
Development and study of novel 3D cell culture systems for invitro growth of cartilage for craniofacial reconstruction applications.
P.I.: Professor R. James Koch, MD
Associate (8/93- 6/94)
Department of Biological Chemistry and Molecular Pharmacology
Harvard Medical School
Boston, Massachusetts
Structural investigation of the SRY response element and its complex with the high mobility group (HMG) motif of the SRY binding protein using Homology
Modeling, 2D/3D NMR and Restrained Molecular Dynamics.
P.I.: Professor Michael Weiss , MD, Ph.D.
Staff Research Associate
(9/90-7/92)
Department of Chemistry University of California, Santa Barbara, Santa Barbara, California
Dynamics Simulation of DNA Structure via Assisted Model Building Using Energy Refinements (AMBER): Kinetic Studies of DNA Methylation.
P.I.: Professor Norbert O. Reich, Ph.D.
Publications/Abstracts/Meetings
Tissue Engineering of Human Septal Cartilage Using Cryogenically Preserved Chondrocytes. Gorti GK, Lo J, Falsafi S, Kosek J, Lum J, Koch RJ, Archives of Otolaryngology(accepted)
Serum-Free Tissue Engineering of Human Septal Cartilage. Falsafi S, Lum J, Kosek J, Gorti GK & Koch RJ, Plastic& Reconstructive Surgery(submitted)
Growth of Tissue-Engineered Human Nasoseptal Cartilage in Simulated Microgravity (Sassan Falsafi and R. James Koch Arch Otolaryngol Head Neck
Surg. 2000;126:759-765)
Meyer TA, Svirsky MA, Castor MB, Falsafi S, Simmons PM. A psychophysically based model of consonant perception by multichannel cochlear implant users. J. Acous. Soc. Am. 1997; 102(5,Pt. 2):3187
An SRY Mutation Causing Human Sex Reversal Resolves a General Mechanism of Structure-Specific DNA Recognition: Application to the Four-Way DNA Junction (R. Peters, C.Y. King, E. Ukiyama, S. Falsafi, P. K. Donahoe, and M.A. Weiss, Biochemistry, 34, 4569-4576, 1995)
Molecular Basis of Mammalian Sexual Determination: Activation of Mullerian Inhibiting Substance Gene Expression (C.M. Haqq, C.-Y. King, E. Ukiyama, S. Falsafi, T.N. Haqq, P.K. Donahoe, M.A. Weiss, Science, 266, 2 Dec. 1994)
Molecular Dynamics Simulation of B-DNA: An Analysis of the Role of Initial Molecular Configuration and Randomly Assigned Velocity Distribution, Long Integration Times, and Non-ConstrainedTermini (Sassan Falsafi & Norbert O. Reich, Biopolymers, 33, 459-473, 1993)
A Comparison Of Right Versus Left Vocal Fold Function In Fluent And Dysfluent Speakers Meghan Dolan, Brooke Evans, Gary Jones, Howard Reid, Sassan Falsafi, The Voice Foundation’s 31st Annual Symposium: Care of the Professional Voice, June 5- 9, 2002 Philadelphia, Pennsylvania
The Effects Of Three Therapy Techniques On Muscle Tension Dysphonia Daniel Miller, Paul Ochs, Gary Jones, Sassan Falsafi, The Voice Foundation’s 31st Annual Symposium: Care of the Professional Voice, June 5- 9, 2002, Philadelphia, Pennsylvania
Sassan Falsafi and R. James Koch: Growth of Tissue-Engineered Human Nasoseptal Cartilage in Simulated Microgravity. Presented at the 1999 Annual Meeting of the American Academy of Otolaryngology-Head and Neck Surgery, New Orleans, La, September 27, 1999.
Koch, R.J. & Falsafi, S.: Facial Reconstruction using Autologous Tissue-Engineered Septal Cartilage. Presented at the Stanford University, Division of Otolaryngology-Head & Neck Surgery 11th Annual Symposium, June 18, 1999
Predicting consonant perception for individual CI users with a psychophysically-based mathematical model, Meyer TA, Svirsky MA, Castor MB, Falsafi S, Miyam oto RT. (1998). Association for Research in Otolaryngology. Twenty-first Midwint er Meeting, St. Petersburg, FL.
A psychophysically based model of consonant perception by multichannel cochlear implant users, Meyer, T. A., Svirsky, M. A., Castor, M. B., Falsafi, Simmons, P. M. (1997). 134th Meeting of the Acoustical Society of America, San Diego, CA.
Modeling the auditory system: From basic science to clinical utility, Meyer, T.A., Svirsky, M.A., Falsafi, S., Gilkey, R.H., Skinner, M.W., Holden, L.K. & Holden, T.A. (1997). 13th Annual Marlow Manion Lectures. Department Of
Industrial Experience/Advanced Process Engineer
3M Data Storage Products Division , Camarillo, CA (8/88-5/90)
Designed, initiated, and coordinated factory experiments to determine the effects of process and formulation changes on Data Cartridge media yield and performance.
Collaborated with manufacturing and R&D personnel in planning and carrying out experiments that resulted in new formulations and coating processes
Designed and coordinated the fabrication of a new filtration system for Data Cartridge magnetic and blackback dispersions
Designed and carried out experiments to determine the effect of turbulent field intensity and volumetric throughput on magnetic dispersions
Conducted preliminary literature search on Ultrasonic Liquid Processing. Fabricated a pilot scale sonicating device for handling process fluids.
Carried out experiments to evaluate the feasibility of using the device in Production
Provided general engineering support in compounding, coating, and fluid handling areas
Collaborated with R&D personnel to solve production problems and communicated the solutions to the manufacturing personnel
Generated technical reports and data packages including statistically computed experimental data in all the above applicable areas
Technical Reports
Coercivity Trends in Data Cartridge Media Filtration
Evaluation: Disposable vs. Standard Media
Particle Counts in Coating Transport, Slitting, and Assembly
Determination of HCA Removal Characteristics of Disposable Filter Media
Data Cartridge Yield Improvement by Means of Rheological Enhancement and Improved Filtration
Data Cartridge Blackback Filtration: Feasibility Study-Disposable Filter Media
Data Cartridge Blackback Filtration: Data Package
Ultrasonic Liquid Processing
Observations of “Frictional Polymer Tester”: Role of Chemistry vs. Process in Polymer Degradation at High Shear Rates
New Feeder Bar – Doctoring Assembly
Teaching ExperienceTeaching Assistant
Department of Chemical Engineering, University of California, Davis
Ech 154B, Mass Transfer Applications(1/87-3/87)
Ech 150B, Fluid Mechanics (4/87-6/87)
Department of Mathematics, University of California, Davis
Math 140, Computer Modeling (4/86-6/86)
Math 22B, Ordinary Differential Equations (4/86-6/86)
Math 16C, Multi-Variable Calculus (1/86-6/86)
Math 16B, Calculus (1/86-3/86)
Community ServiceCommunity Service
Student Volunteer
Department of Emergency, St. Francis Hospital, Santa Barbara, CA 9/90-12/90.
Department of surgery, St. Francis Hospital, Santa Barbara, CA 12/90-6/91.
Intensive Care Unit, Cottege Hospital, Santa Barbara, CA 1/92-3/92.
Skills
Surgical experience – Available upon request
Flow Visualization: Laser illuminated dark background still photography
Numerical Simulation Techniques: Finite Element Methods, Finite Difference
Methods
Computational Algorithms: 3D Reconstruction, AMBER, CDW, MidasPlus, CORMA,
MARDIGRAS
Computer Environments: UNIX, Silicon Graphics, Apple, PC
High Level Programming Language: Fortran, UNIX Shell / Operating System (V),
HyperText Markup Language (HTML)
Familiarity With Analytical Techniques: XRF, ICP, FTIR, SEM, Light Scattering,
2D/3D FT-NMR
Excellent written and verbal communications skills

