Boston University Medical Campus
Neurology

Selected Faculty Publications

Below are selected publications of faculty in the Department of Neurology:

 

Ivan CS, Seshadri S, Beiser A, Au R, Kase CS, Kelly-Hayes M, Wolf PA. Dementia after stroke: The Framingham Study. Stroke 35: 1264-1269, 2004.

Jeerakathil T, Wolf PA, Beiser A, Hald JK, Au R, Kase CS, Massaro JM, DeCarli C. Cerebral microbleeds: Prevalence and associations with cardiovascular risk factors in the Framingham Study. Stroke 35: 1831-1835, 2004.

Seshadri S, Wolf PA, Beiser A, Elias MF, Au R, Kase CS, D’Agostino RB, DeCarli C. Stroke risk profile, brain volume, and cognitive function: The Framingham Offspring Study. Neurology 63: 1591-1599, 2004.

Kurth T, Slomke MA, Kase CS, Cook NR, Lee I, Gaziano JM, Diener HC, Buring JE. Migraine, headache, and the risk of stroke in women: a prospective study. Neurology 64: 1020-1026, 2005.

Kurth T, Gaziano JM, Rexrode KM, Kase CS, Cook NR, Manson JA, Buring JE. Prospective study of body mass index and risk of stroke in apparently healthy women. Circulation 111: 1992-1998, 2005.

Kahn JH, Viereck J, Kase CS, Jeerakathil T, Romero R, Mehta SD, Kociol R, Babikian VL. The use of intravenous recombinant tissue plasminogen activator in acute ischemic stroke. Journal of Emergency Medicine 29: 273-277, 2005.

Kase CS. The recombinant factor VIIa experience. Stroke 36: 2321-2322, 2005.

Estol CJ, Kase CS. Intracerebral hemorrhage after carotid revascularization procedures. Seminars in Cerebrovascular Diseases and Stroke 5: 194-201, 2005.

Park S, Kase CS. Re-anticoagulation after warfarin-related intracerebeal hemorrhage in patients with mechanical heart valves: the clinical dilemma. Seminars in Cerebrovascular Diseases and Stroke 5: 221-224, 2005.

Seshadri S, Beiser A, Kelly-Hayes M, Kase CS, Au R, Kannel WB, Wolf PA. The lifetime risk of stroke: estimates from the Framingham Study. Stroke 37: 345-350, 2006.

Juvela S, Kase CS,. Advances in intracerebral hemorrhage management. Stroke 37: 301-304, 2006.

Kurth T, Moore SC, Gaziano JM, Kase CS, Stampfer MJ, Berger K, Buring JE. Healthy lifestyle and the risk of stroke in women. Archives of Internal Medicine 166:1403-1409, 2006.

Bowman TS, Kurth T, Kase CS, Sesso HD, Gaziano JM. Blood pressure measures and risk of total, ischemic and hemorrhagic stroke in men. Neurology 67: 820-823, 2006.

Carandang R, Seshadri S, Beiser A, Kelly-Hayes M, Kase CS, Kannel WB, Wolf PA. Temporal trends in incidence, lifetime risk, severity and mortality of stroke over the past fifty years: The Framingham Study. Journal of the American Medical Association 296: 2939-2946, 2006.

Salaycik KJ, Kelly-Hayes M, Beiser A, Nguyen A-H, Brady SM, Kase CS, Wolf PA. Depressive symptoms and risk of stroke: The Framingham Study. Stroke 38: 16-21, 2007.

Aguilar MI, Hart RG, Kase CS, Freeman WD, Hoeben BJ, Garcia RC, Ansell JE, Mayer SA, Norrving B, Rosand J, Steiner T, Wijdicks EFM, Yamaguchi T, Yasaka M. Treatment of warfarin-associated intracerebral hemorrhage: Literature review and expert opinion. Mayo Clinic Proceedings 82:82-92, 2007.

Kurth T, Everett BM, Buring JE, Kase CS, Ridker PM, Gaziano JM. Lipid levels and the risk of stroke in women. Neurology 68:556-562, 2007.

Sherman DG, Albers GW, Bladin C, Fieschi C, Gabbai AA, Kase CS, O’Riordan W, Pineo GF, for the PREVAIL Investigators. The efficacy and safety of enoxaparin versus unfractionated heparin for the prevention of venous thromboembolism after acute ischaemic stroke (PREVAIL study): An open-label randomized comparison. Lancet 369:1347-1355, 2007.

Broderick J, Connolly S, Feldmann E, Hanley D, Kase CS, Krieger D, Mayberg M, Morgenstern L, Ogilvy CS, Vespa P, Zuccarello M. Guidelines for the management of spontaneous intracerebral hemorrhage in adults: 2007. Stroke 38:2001-2023, 2007.

Rudolph J, Chaglassian A, Pochay V, Wigginton J, Sorond F, Crittenden M, Babikian V.L. Severe extracranial internal carotid artery stenosis impacts cerebral hemodynamics during coronary artery bypass graft surgery. Neurology. 68:(S1): A131, 2007.

Wigginton J, Rudolph J, Babikian V, Khuri S, Pochay V, Marcantonio E.. Microemboli during cardiac surgery are not associated with postoperative delirium. J Am Geriatr Soc. 55:(4S): S218, 2007.

Rudolph J, Tilahun D, Treanor R, Pochay V, Mahendrakar M, Sagar P, Babikian V.. Use of large bore syringe creates significantly fewer high intensity transient signals into cardiopulmonary bypass sytem than a small bore syringe. Perfusion. 21: 67-71, 2006.

Romero JR, Babikian VL, Katz DI, Finkelstein SP.. Neuroprotection and stroke rehabilitation: Modulation and enhancement of recovery. Behavioral Neurology. 17: 17-24, 2006.

Wolk DA, Schacter DL, Berman AR, Holcomb PJ, Daffner KR, Budson AE. An electrophysiological investigation of the relationship between conceptual fluency and familiarity. Neuroscience Letters 2004 369 150-155.

Gallo DA, Sullivan AL, Daffner KR, Schacter DL, Budson AE. Associative recognition in Alzheimer’s disease: Evidence for impaired recall-to-reject. Neuropsychology 2004 18 556-563.

Budson AE, Simons JS, Sullivan AL, Beier JS, Solomon PR, Scinto LF, Daffner KR, Schacter DL. Memory and emotions for the September 11, 2001, terrorist attacks in patients with Alzheimer’s disease, patients with mild cognitive impairment, and healthy older adults. Neuropsychology 2004 18 315-327. See also supplementary materials Read the APA Monitor magazine press release

Pierce BH, Sullivan AL, Schacter DL, Budson AE. Comparing source-based and gist-based false recognition in aging and Alzheimer’s disease. Neuropsychology 2005 19 411-419.

Wolk DA, Schacter DL, Berman AR, Holcomb PJ, Daffner KR, Budson AE. Patients with Alzheimer’s disease attribute conceptual fluency to prior experience. Neuropsychologia 2005 43 1662-1672.

Budson AE, Droller DBJ, Dodson CS, Schacter DL, Rugg MD, Holcomb PJ, Daffner KR. Electrophysiological dissociation of picture versus word encoding: Understanding the distinctiveness heuristic as a retrieval orientation. Journal of Cognitive Neuroscience 2005 17 1181-1193.

Glick TH, Budson AE. Education and communication about memory: Using the terminology of cognitive neuroscience. American Journal of Alzheimer’s Disease and Other Dementias 2005 20 141-143.

Simons JS, Lee ACH, Graham KS, Verfaellie M, Koutstaal W, Hodges JR, Schacter DL, Budson AE. Failing to get the gist: Reduced false recognition of semantic associates in semantic dementia. Neuropsychology 2005 19 353-261.

Budson AE, Dodson CS, Daffner KR, Schacter DL. Metacognition and false recognition in Alzheimer’s disease: Further exploration of the distinctiveness heuristic. Neuropsychology 2005 19 253-258.

Budson AE, Dodson CS, Vatner JM, Daffner KR, Black PM, Schacter DL. Metacognition and false recognition in patients with frontal lobe lesions: The distinctiveness heuristic. Neuropsychologia 2005 43 860-871.

Budson AE, Price BH. Memory Dysfunction. The New England Journal of Medicine 2005 352 692-699. See also Supplementary Appendix.

Gallo DA, Shahid KR, Olson MA, Solomon TM, Schacter DL, Budson AE. Overdependence on degraded gist memory in Alzheimer’s disease. Neuropsychology 2006 20 625-632.

Wolk DA, Schacter DL, Lygizos M, Mandu-Sen N, Holcomb PJ, Daffner KR, Budson AE. ERP correlates of recognition memory: Effects of retention interval and false alarms. Brain Research 2006 1096 148-162.

Budson AE, Wolk DA, Chong H, Waring JD. Episodic memory in Alzheimer’s disease: Separating response bias from discrimination. Neuropsychologia 2006 44 2222-2232.

Budson AE, Todman RW, Chong H, Adams EH, Kensinger EA, Krangel TS, Wright CI. False recognition of emotional word lists in younger adults, older adults, and patients with Alzheimer’s disease. Cognitive and Behavioral Neurology 2006 19 71-78.

Budson AE, Mather M, Chong H. Memory for Choices in Alzheimer’s Disease. Dementia and Geriatric Cognitive Disorders 2006 22 150-158.

Mitchell JP, Sullivan AL, Schacter DL, Budson AE. Misattribution errors in Alzheimer’s disease: The illusory truth effect. Neuropsychology 2006 20 185-192.

Ally BA, Jones GE, Cole JA, Budson AE. The P300 component in patients with Alzheimer’s disease and their biological children. Biological Psychology 2006 72 180-187.

Budson AE, Todman RW, Schacter DL. Gist memory in Alzheimer’s disease: Evidence from categorized pictures. Neuropsychology 2006 20 113-122.

Wolk DA, Schacter DL, Lygizos M, Mandu-Sen N, Chong H, Holcomb PJ, Daffner KR, Budson AE. ERP correlates of Remember/Know decisions: Association with the late posterior negativity. Biological Psychology 2007 75 131-135.

Ally BA, Budson AE. The worth of pictures: Using high density event-related potentials to understand the memorial power of pictures and the dynamics of recognition memory. NeuroImage 2007 35 378-395.

Ally BA, Jones GE, Cole JA, Budson AE. Sensory gating in patients with Alzheimer’s disease and their biological children. American Journal of Alzheimer’s Disease and Other Dementias 2007 21 439-447.

Frank S., Jozefowicz R. The Challenges of Residents Teaching Neurology. The Neurologist 10(4):216-220, July 2004.

Gill D., Frank S. The Neurology Resident as Teacher: Evaluating and Improving Our Role. Neurology 63 (7); Oct 12, 2004:1334-1338.

Richard I.H., Frank S., McDermott M., Wang H., Justus A., LaDonna K., Kurlan R. The Ups and Downs of Parkinson’s Disease: A Prospective Study of Mood and Anxiety Fluctuations in PD. Cognitive and Behavioral Neurology 17(4); December 2004:201-207.

Richard I, Frank S, LaDonna K, Wang H, McDermott M, Kurlan R. Mood Fluctuations in Parkinson’s Disease: A Pilot Study Comparing the Effects of Intravenous and Oral Levodopa Administration. Neuropsychiatric Disease and Treatment 1(3); July 2005:261-268.

Kim S., Frank S, Holloway R, Zimmerman C, Wilson R, Kieburtz K. Science and ethics of sham surgery: A survey of Parkinson’s disease clinical researchers. Archives of Neurology 62;Sept 2005: 1357-60.

Frank S, Barbano R. Trauma-Induced Spinal Vascular Event Producing Hemipseudoathetosis. Movement Disorders 20 (10); October 2005: 1378-1380.

Frank S, Kieburtz K, Holloway R, Kim S. What is the Risk of Sham Surgery in Parkinson’s Disease Clinical Trials? A Review of Published Reports. Neurology 65; October 2005: 1101-1103. [With editorial and letter to the editor].

Huntington Study Group (Frank S, third author and medical monitor). Tetrabenazine as Anti-Chorea Therapy in Huntington’s Disease: A Randomized Control Trial. Neurology 66 (3);Feb 14, 2006:366-372.

Kim S, Holloway R, Frank S, Beck C, Zimmerman C, Wilson R, Kieburtz K. Volunteering for early phase gene transfer research in Parkinson’s disease. Neurology 2006 Apr 11;66(7):1010-5. Epub 2006 Mar 15.

Frank S. Training Matters: Teaching Residents to Be Teachers. Nature Clinical Practice Neurology. Nature Clinical Practice Neurology 3(4); April 2007:235.

Frank S, Ondo W, Hunter C, Marshall F, Walker F, Eberly S, Factor S, Fahn S, Hunt V, Oakes D, Plumb S, Shinaman A, Shoulson I, Zhao H, Jankovic J. A Randomized, Double-Blind, Placebo-Controlled, Staggered Withdrawal Study in Patients with Huntington’s Disease Treated with Tetrabenazine. Clinical Neuropharmacology. In press.

Cupples LA, Farrer LA, Sadovnick D, Relkin N, Whitehouse P, Green RC: Estimating risk curves for first-degree relatives of patients with Alzheimer’s disease: The REVEAL Study. Genetics in Medicine, 6:192-196, 2004.

Roberts JS, Barber M, Brown T, Cupples LA, Farrer L, LaRusse SA, Post S, Quaid K, Ravdin L, Relkin N, Sadovnick D, Whitehouse P, Woodard J, Green RC: Who seeks genetic susceptibility testing for Alzheimer’s disease? Findings from a multi-site, randomized clinical trial. Genetics in Medicine, 6:197-203, 2004.

Henderson VW, Benke KS, Green RC, Cupples LA, Farrer LA: Postmenopausal hormone therapy and Alzheimer’s disease risk: Interaction with age. Journal of Neurology, Neurosurgery and Psychiatry, 76:103-105, 2005.

LaRusse SA, Roberts JS, Marteau T, Katzen H, Linnenbringer E, Barber M, Whitehouse P, Quaid K, Brown T, Green RC, Relkin N: Predictive genetic testing for Alzheimer’s disease: Impact on perceived risk of Alzheimer’s disease. Genetics in Medicine, 7:48-53, 2005.

Yip AG, Green RC, Huyck M, Cupples LA, Farrer LA. Nonsteroidal anti-inflammatory drug use and Alzheimer disease risk: The MIRAGE Study. Biomed Central Geriatrics 5:2, 2005

Marteau T, Roberts JS, LaRusse SA, Green RC: Genetic susceptibility testing versus family history-based risk assessment: Impact upon perceived risk of Alzheimer’s disease. Risk Analysis, 25:397-404. 2005.

Zick CD, Matthews C, Roberts JS, Cook-Deegan, R, Pokorski RJ, Green RC: Genetic susceptibility testing for Alzheimer’s disease and its impact on health insurance behavior. Health Affairs, 24:483-490, 2005.

Yip G, McKee A, Green RC, Wells J, Young H, Cupples LA, Farrer LA: APOE, vascular pathology and the AD brain. Neurology, 65:259-265, 2005.

Lyketsos CG, Toone L, Tschanz J, Rabins PV, Steinberg M, Onyike CU, Corcoran C, Norton M, Zandi P, Breitner JC, Welsh-Bohmer K, Anthony J, Ostbye T, Bigler E, Pieper C, Burke J, Plassman B, Green RC, Steffens DC, Klein L, Leslie C, Townsend JJ, Wyse BW, Munger R, Williams M. Population-based study of medical comorbidity in early dementia and “cognitive impairment, no dementia (CIND)”: association with functional and cognitive impairment: The Cache County Study. Am J Geriatr Psychiatry, 13:656-654, 2005.

Roberts JS, Cupples LA, Relkin NR, Whitehouse PJ, Green RC: Genetic risk assessment for adult children of people with Alzheimer’s disease. J Ger Psychiatr Neurol, 18:250-255, 2005.

Hurley AC, Harvey R, Roberts JS, Wilson-Chase C, Lloyd S, Prest J, Lock M, Horvath KJ, Green RC: Genetic susceptibility for Alzheimer’s disease: Why did adult offspring seek testing? Am J Alzheimer’s Dis Oth Dem, 20:374-381, 2005.

Erlich PM, Lunetta KL, Cupples LA, Huyck M, Green RC, Baldwin CT, Farrer LA: Polymorphisms in the PON gene cluster are associated with Alzheimer disease. Hum Mol Genetics, 15:77-85, 2006.,

Green RC, McNagny SE, Jayakumar P, Cupples LA, Benke K, Farrer LA: Statin use and the risk of Alzheimer’s disease. Alzheimer’s & Dementia, 2:96-103, 2006.

Tsai DH, Green RC, Benke KS, Silliman RA, Farrer LA: Predictors of subjective memory complaint in cognitively normal relatives of patients with Alzheimer’s disease. Journal of Neuropsychiatry and Clinical Neuroscience, 18:384-388, 2006.

Wolozin B, Manger J, Bryant R, Cordy J, Green RC, McKee A. Cholesterol, Alzheimer’s disease and statins: Re-assessing the relationship between cholesterol, statins and Alzheimer’s disease. Acta Neuropathologica 114:63-70, 2006.

Tschanz JT, Welsh-Bohmer KA, Lyketsos CG, Corcoran C, Green RC…. Breitner JCS: Conversion to dementia from mild cognitive disorder: the Cache County Study. Neurology, 67:229-234, 2006.

Akomolafe A, Lunetta KL, Erlich PM, Cupples LA, Baldwin CT, Huyck M, Green RC, Farrer LA: Genetic association between endothelial Nitric Oxide Synthase (NOS3) and Alzheimer disease. Clinical Genetics, 70:49-56, 2006.

Jefferson AL, Wong S, Bolen E, Ozonoff A, Green RC, Stern RA: Cognitive correlates of HVOT performance differ between individuals with mild cognitive impairment and normal controls. Archives of Clinical Neuropsychology, 21:405-412, 2006.

Binetti G, Benussi L, Roberts S, Villa A, Pasqualetti P, Sheu C-F, Gigola L, Lussignoli G, Dal Forno G, Barbiero L, Corbellini, Green RC, Rossini PM, Ghidoni R. Areas of intervention for genetic counselling of dementia: Cross-cultural comparison between Italians and Americans. Patient Education & Counseling, 64:285-293, 2006.

Green RC,Dekosky ST: Primary prevention trials in Alzheimer’s disease. Neurology 67:S2-5, 2006.

Gooding HC, Linnebringer EL, Burack J, Roberts JS, Green RC, Biesecker BB: Genetic susceptibility testing for Alzheimer disease: Motivation to obtain information and control as precursors to coping with increased risk. Patient Education & Counseling, 64:259-267, 2006.

Eckert SL, Katzen H, Roberts JS, Barber M, Ravdin LD, Relkin NR, Whitehouse PJ, Green RC: Recall of disclosed Apolipoprotein E genotype and lifetime risk estimate for Alzheimer’s disease: The REVEAL Study. Genetics in Medicine 8:746-751, 2006.

Akomolafe A, Beiser A, Meigs JB, Au R, Green RC, Farrer LA, Wolf PA, Seshadri S: Diabetes mellitus and risk of developing Alzheimer disease. Arch Neurol 63:1551-1555, 2006.

ADAPT Research Group. Cardiovascular and cerebrovascular events in the randomized, controlled Alzheimer’s Disease Anti-inflammatory Prevention Trial (ADAPT). PloS Clinical Trials, 1(7):e33, 2006.

Rogaeva E, Meng Y, Lee JH, Gu Y-J, Kawarai T, Katayama T, Erlich PM, Baldwin CT, Cheng R, Hasegawa H, Chen F, Shibata N, Lunetta KL, Cupples LA, Green RC….St. George-Hyslop, P: The sortilin-related receptor SorLA is associated with Alzheimer’s disease. Nature Genetics, 39:168-77, 2007.

Onyike CU, Sheppard JME, Tschanz JT, Mayer LS, Green RC… Lyketsos CG: Epidemiology of apathy in older adults: The Cache County Study. J Ger Psychiatry, 15(5):365-75, 2007.

Jefferson AL, Wong S, Gracer TS, Ozonoff A, Green RC, Stern RA. Geriatric performances on the Boston Naming Test-30 item even version. Applied Neuropsychology. in press.

Lyketsos CG, Breitner JCS, Green RC, Martin BK, Piantadosi S, Sabbagh M: Naproxen or celecoxib treatment and the incidence of Alzheimer’s disease: Early results from the Alzheimer’s Disease Anti-inflammatory prevention trial (ADAPT). Neurology, in press.

Lunetta KL, Erlich PM, Cuenco KT, Cupples LA, Green RC, Farrer LA, DeCarli C: Heritability of magnetic resonance imaging (MRI) traits in Alzheimer disease cases and their siblings in the MIRAGE Study. Alz Dis Oth Disorders, in press.

Cuenco KR, Green RC, Zhang J, Lunetta K, Erlich PM, Cupples LA, Farrer LA, DeCarli C: Magnetic resonance imaging traits in siblings discordant for Alzheimer disease. J Neuroimaging, in press.

Cosentino SA, Jefferson AL, Kaplan E, Chute D, Libon DJ. Clock drawing errors in dementia: Neuropsychological and neuroanatomical considerations. Behavioral & Cognitive Neurology, 2004; 17(2):74-83.

Cosentino SA, Jefferson AL, Carey ME, Price CC, Davis KL, Swenson R, Libon DJ. The clinical diagnosis of vascular dementia: A comparison among four classification systems and a proposal for a new paradigm. The Clinical Neuropsychologist, 2004; 18(1):6-21.

Gunstad J, MacGregor KL, Paul RH, Poppas A, Jefferson AL, Todaro J, Cohen RA. Cardiac rehabilitation improves cognitive performance: A preliminary examination. Journal of Cardiopulmonary Rehabilitation, 2005; 25:173-176.

Brickman AM, Paul RH, Cohen RA, Williams LM, MacGregor KL, Jefferson AL, Tate DF, Gunstad J, Gordon E. Category and phonemic verbal fluency across the adult lifespan: Relationship to EEG theta power. Archives of Clinical Neuropsychology, 2005; 20:561-573.

Paul RH, Brickman AM, Navia B, Hinkin C, Malloy PF, Jefferson AL, Cohen RA, Tate DF, Flanigan TP. Apathy is associated with volume of the nucleus accumbens in patients infected with HIV. Journal of Neuropsychiatry & Clinical Neurosciences, 2005; 17:167-171.

Paul RH, Gunstad J, Poppas A, Tate DF, Forman D, Brickman AM, Jefferson AL, Hoth K, Cohen RA. Neuroimaging and cardiac correlates of cognitive function among patients with cardiac disease. Cerebrovascular Diseases, 2005; 20(2):129-133.

Paul RH, Haque O, Gunstad J, Tate DF, Grieve SM, Hoth K, Brickman AM, Cohen RA, Lange K, Jefferson AL, MacGregor K, Gordon E. Subcortical hyperintensities impact cognitive function among a select subset of healthy elderly. Archives of Clinical Neuropsychology, 2005; 20(6):697-704.

Price CC, Jefferson AL, Merino JG, Heilman KM, Libon DJ. Subcortical vascular dementia: Integrating neuropsychological and neuroradiological data. Neurology, 2005; 65(3):376-382.

Gunstad J, Cohen RA, Tate D, Paul R, Poppas A, Hoth K, MacGregor K, & Jefferson AL. Blood pressure variability and white matter hyperintensities in older adults with cardiovascular disease. Blood Pressure, 2005; 14(6):353-358.

Jefferson AL, Glosser G, Detre JA, Sinson G, Liebeskind DS. Neuropsychological and perfusion MRI correlates of revascularization in a case of moyamoya syndrome. American Journal of Neuroradiology, 2006; 27(1):98-100.

Gunstad J, Bausserman L, Paul RH, Tate D, Hoth K, Poppas A, Jefferson AL, Cohen RA. C-reactive protein, but not homocysteine, is related to cognitive dysfunction in older adults with cardiovascular disease. Journal of Clinical Neurosciences, 2006; 13(5): 540-546.

Gunstad J, Poppas A, Smeal S, Paul RH, Tate DF, Jefferson AL, Forman D, Cohen RA. Relation of brain natriuretic Peptide levels to cognitive dysfunction in adults >55 years of age with cardiovascular disease. American Journal of Cardiology, 2006; 98(4): 538-540.

Jefferson AL, Paul RH, Ozonoff A, Cohen RA. Evaluating elements of executive functioning as predictors of instrumental activities of daily living (IADLs). Archives of Clinical Neuropsychology, 2006; 21(4): 311-320.

Jefferson AL, Barakat LP, Giovannetti T, Paul RH, Glosser G. Object perception impairments predict instrumental activities of daily living in Alzheimer’s disease. Journal of Clinical & Experimental Neuropsychology, 2006; 28(6): 884-897.

Jefferson AL, Cahn-Weiner D, Boyle P, Paul RH, Gordon N, Moser D, Cohen RA. Cognitive predictors of changes in activities of daily living among patients with vascular dementia. International Journal of Geriatric Psychiatry, 2006; 21(8):752-754.

Jefferson AL, Wong S, Bolen E, Ozonoff A, Green RC, Stern RA. Cognitive predictors of HVOT performance differ between patients with mild cognitive impairment and normal controls. Archives of Clinical Neuropsychology, 2006; 21:405-412.

Hoth KF, Tate DF, Poppas A, Gunstad J, Forman D, Moser DJ, Paul RH, Jefferson AL, Haley A, Cohen RA. Endothelial dysfunction is associated with cerebral white matter hyperintensities in older adults with cardiovascular disease. Stroke, 2007; 38(2):308-312.

Jefferson AL, Paul RH, Poppas A, Cohen RA. Systemic hypoperfusion is associated with executive dysfunction in geriatric cardiac patients. Neurobiology of Aging, 2007; 28(3):477-483.

Keary TA, Gunstad J, Poppas A, Paul RH, Jefferson AL, Hoth KF, Sweet LH, Forman DE, Cohen RA. Blood pressure variability and Dementia Rating Scale performance in older adults with cardiovascular disease. Cognitive and Behavioral Neurology, 2007; 20(1):73-77.

Jefferson AL, Massaro JM, Larson MG, Wolf PA, Au R, D’Agostino RB, Seshadri S, Lipinska I, Meigs JB, Keaney Jr. JF, Vasan RS, Beiser A, Benjamin EJ, DeCarli C. Inflammatory biomarkers are associated with total brain volume: The Framingham Heart Study. Neurology, 2007; 68: 1032-1038.

Haley AP, Forman DE, Poppas A, Hoth KF, Gunstad J, Jefferson AL, Paul, RH, Ler ASH, Sweet LH, Cohen, RA. Carotid artery intima-media thickness and cognition in cardiovascular disease. International Journal of Cardiology, (In press).

Jefferson AL, Wong S, Gracer TS, Ozonoff A, Green RC, Stern RA. Geriatric performances on the Boston Naming Test-30 item even version. Applied Neuropsychology. (In press).

Jefferson AL, Tate DF, Poppas A, Brickman, AM, Paul RH, Gunstad J, Cohen RA. Lower cardiac output is associated with white matter hyperintensities in older adults with cardiovascular disease. Journal of the American Geriatrics Society. (In press).

Katz DI, Giacino JT: Disorders of consciousness. In M Rizzo, PJ Eslinger (eds.), Principles and Practice of behavioral neurology and neuropsychology. Philadelphia: Elsevier Saunders, 2004.

Katz DI, White DK, Alexander MP, Klein RB: Recovery of ambulation after traumatic brain injury. Arch Phys Med Rehabil. 85: 865-869, 2004.

White DK, Katz DI, Ellis T, Buyan Dent L, Saint Hilaire M: Rehabilitation of patients with atypical parkinsonian disorders. In Litvan I (ed.): Atypical Parkinsonian Disorders: Clinical and Research Aspects. Current Clinical Neurology Series. Humana Press, 2005.

Stuss DT, Alexander MP, Shallice T, Picton TW, Binns MA, Macdonald R, Borowiec A, Katz DI: Multiple frontal systems controlling response speed. Neuropsychologia 43: 396-417, 2005.

Whyte J, Katz DI, Long D, DiPasquale MC, Polansky M, Kalmar K, Giacino J, Childs N, Mercer W, Novak P, Maurer P, Eifert B: Predictors of Outcome in Prolonged Posttraumatic Disorders of Consciousness and Assessment of Medication Effects: A Multicenter Study. Arch Phys Med Rehabil, 86: 453-62, 2005.

Povlishock JT, Katz DI: Update of neuropathology and neurological recovery after traumatic brain injury. J Head Trauma Rehabilitation, 20: 76-94, 2005.

Katz DI: Emerging minds: pharmaceutical interventions offer potential to remediate the effects of TBI. Advance for Directors in Rehab, 15(3): 21-24, 2006.

Romero JR, Babikian VL, Katz DI, Finklestein SP: Neuroprotection and stroke rehabilitation: modulation and enhancement of recovery. Behavioural Neurology, 17: 17-24, 2006.

Katz DI, Ashley MJ, O’Shanick GJ, Connors SH: Cognitive rehabilitation: the evidence, funding and case for advocacy in brain injury. McLean, VA: Brain Injury Association of America, 2006.

Warden DL; Gordon B; McAllister TW; Silver JM; Barth JT; Bruns J; Drake A; Gentry T; Jagoda A; Katz DI; Kraus J; Labbate LA; Ryan LM; Sparling MB; Walters B; Whyte J; Zapata A; Zitnay G. Guidelines for the pharmacologic treatment of neurobehavioral sequelae of traumatic brain injury. J Neurotrauma, 23: 1468-1501, 2006.

Silver JM, Koumaras B, Chen M, Mirski D, Potkin SG, Reyes P, Warden D, Harvey PD, Arciniegas D, Katz DI, Gunay I: The Effects of Rivastigmine on Cognitive Function in Patients with Traumatic Brain Injury. Neurology, 67: 748-755, 2006.

Zasler ND, Katz DI, Zafonte RD (eds.): Brain injury medicine: principles and practice. New York: Demos, 2007.

Katz DI, Zasler ND, Zafonte RD: Clinical continuum of care and natural history. In Zasler ND, Katz DI, Zafonte RD (eds.): Brain injury medicine: principles and practice. New York: Demos, 2007.

Giacino JT, Katz DI, Schiff N: Assessment and Management of Individuals with Disorders of Consciousness. In Zasler ND, Katz DI, Zafonte RD (eds.): Brain injury medicine: principles and practice. New York: Demos, 2007.

Albright CD, Siwek DF, Craciunescu CN, Mar MH, Kowall NW, Williams CL, Zeisel SH. Choline availability alters the localization of calretinin in developing and aging mouse hippocampus. Nutr Neurosci. 2003;6:129-34.

McKeon-O’Malley C, Siwek D, Lamoureux JA, Williams CL, Kowall NW. Prenatal choline deficiency decreases the cross-sectional area of cholinergic neurons in the medial septal nucleus. Brain Res. 2003;977:278-83.

Sheridan PL, Solomont J, Kowall N, Hausdorff, JM. Influence of Executive Function on Locomotor Function: Divided Attention Increases Gait Variability in Alzheimer’s Disease J Amer Ger Soc 2003; 51:1633-37

Ferrante RJ, Kubilus JK, Lee J, Ryu H, Beesen A, Zucker B, Smith K, Kowall NW, Ratan RR, Luthi-Carter R, Hersch SM. Histone deacetylase inhibition by sodium butyrate chemotherapy ameliorates the neurodegenerative phenotype in Huntington’s disease mice. J Neurosci. 2003;23:9418-27.

Dedeoglu A, Choi JK, Cormier K, Kowall NW, Jenkins BG. Magnetic resonance spectroscopic analysis of Alzheimer’s disease mouse brain that express mutant human APP shows altered neurochemical profile. Brain Res. 2004 Jun 25;1012:60-5.

Dedeoglu A, Cormier K, Payton S, Tseitlin KA, Kremsky JN, Lai L, Li X, Moir RD, Tanzi RE, Bush AI, Kowall NW, Rogers JT, Huang X. Preliminary studies of a novel bifunctional metal chelator targeting Alzheimer’s amyloidogenesis. Exp Gerontol. 2004 Nov-Dec;39(11-12):1641-9.

Kraytsberg Y, Kudryavtseva E, McKee AC, Geula C, Kowall NW, Khrapko K. Mitochondrial DNA deletions are abundant in neurons of the aged human substantia nigra and are associated with respiratory chain deficiency. Nature Genetics 2006;38:518-20

McKee AC, Au, R, Cabral, HJ, Kowall NW, Seshadri, S, Kubilus CA, Drake J, Philip A. Wolf PA. Visual Association Pathology in Preclinical Alzheimer Disease. J Neuropathol Exptl Neurol 2006; 65:621-30.

Lee J, Kosaras B, Aleyasin H, Han JA, Park DS, Ratan RR, Kowall NW, Ferrante RJ, Lee SW, Ryu H. Role of cyclooxygenase-2 induction by transcription factor Sp1 and Sp3 in neuronal oxidative and DNA damage response. FASEB J. 2006;20:2375-7

Mellott TJ, Kowall NW, Lopez-Coviella I, Blusztajn JK. Prenatal choline deficiency increases choline transporter expression in the septum and hippocampus during postnatal development and in adulthood in rats. Brain Res 2007, in press.

McNamara P, Benson E, McGeeney B, Brown A, Albert ML. Modes of Remembering in Patients With Chronic Pain: Relation to Current Pain. J Nerv Ment Dis. 2005 Jan;193(1):53-57.

McGeeney BE. Cluster headache pharmacotherapy. Am J Ther. 2005 Jul-Aug;12(4):351-8.

McGeeney BE, Barest G, Grillone G. Thunderclap headache from complicated sinusitis. Headache 2006;46:517-520.

McGeeney BE. Headache and Anosmia. Headache 2006;46:1199.

McGeeney BE. Valsalva-Induced Cluster Headache. J Headache Pain 2006 7: 416-418

Loder E, Rizzoli P, McGeeney, B et al. Cluster headache treatment dilemmas: the experts respond. Curr Pain Headache Rep. 2007 Apr;11(2):141-7.

Gao W, Eisenhauer PB, Conn K, Lynch JA, Wells JM, Ullman MD, McKee A, Thatte HS, Fine RE. Insulin degrading enzyme is expressed in the human cerebrovascular endothelium and in cultured human cerebrovascular endothelial cells. Neurosci Lett. 2004 371 (1):6-11

Conn K, Gao W, McKee A, Lan MS, Ullman MD, Eisenhauer PB, Fine R and Wells JM. Identification of the protein disulfide isomerase family member PDIp in experimental Parkinson’s diease and Lewy Body Pathology, Brain Res. 2004 1022 (1-2):164-72

Yip AG, McKee AC, Wells J, Green RC, Young H, Cupples A, Farrer LA. ApoE, vascular pathology, and the AD brain. Neurology, 2005; 65:259-265.

Wolozin B, Manger J, Bryant R, Cordy J, Green R, McKee A. Cholesterol, Alzheimer’s disease and statins: re-assessing the relationship between cholesterol, statins and Alzheimer’s disease. Acta Neuropathologica, in press.

Kraytsberg Y, Kudryavtseva E, McKee AC, Geula C, Kowall NW, Krapko K. Mitochondrial DNA deletions are abundant and cause functional impairment of select human substantia nigra neurons. Nature Genetics, 2006 May;38(5):518-20.

McKee, AC, Au R, Cabral HJ, Kowall NW, Seshadri, S, Kubilus C, Drake J, Wolf P. Visual Association Pathology in Preclinical AD. Journal Neuropath Exp Neurol 2006 June; 65(6):621-630.

Morrell, MJ and Montouris, GD, Reproductive disturbances in patients with epilepsy, Cleveland Clinic Journal of Medicine, 2004 Suppl 2, Vol 71, S19-24.

Montouris, GD, Commentary on Muira, Seizure: European Journal of Epilepsy, Vol 13, Suppl 1, December, 2004, S24-25.

Uthman, B, Miller, S, Montouris, GD, Safety of Open-label 25 and 50 mg Zonisamide in the Initiation of Therapy in Patients with Epilepsy, an uncontrolled, open-label study, Curr Med Res Opin, 2004:20:837-842.

Montouris, GD, Women and Epilepsy: Special Considerations, Johns Hopkins Advanced Studies in Nursing, Vol 2, Number 5, December, 2004, p 183-190.

Caserta, F, Montouris, GD, New Onset Epilepsy in Women: the Art and Science of Individualized Care for Women, Johns Hopkins Advanced Studies in Nursing, Vol 2, Number 5, December, 2004 ,p 175-176

Long, Lucretia, Montouris, GD, Knowledge of Women’s Issues and Epilepsy: A Survey of Healthcare Professionals, Epilepsy and Behavior, Vol 6, Number 1, February 2004.

Browne, TR, Holmes, GL, Montouris, GD,Special Considerations in Women and Elderly, in Handbook of Epilepsy, Lippincott, Williams and Wilkins, Philadelphia, 2004:216-226.

Blumer, D, Montouris, G, Davies, K, The interictal dyphoric disorder: recognition, pathogenesis, and treatment of the major psychiatric disorder of epilepsy, Epilepsy and Behavior, Vol 5,Oct, 2004, p 826-840.

Montouris, GD, Safety of the newer antiepileptic drug oxcarbazepine during pregnancy, Cur Med Res and Opin, Vol 21, Number 5, May 2005, p 693-701.

Montouris, GD, Traditional Anitepileptics: Adverse Events and Their Impact on Quality of Life, PeerView in Review, 2005,p 6-8.

Montouris, GD, Morris,GL, Reproductive and Sexual Dysfunction in Men with Epilepsy, Epilepsy and Behavior, Vol 7, Suppl 2, December, 2005, p S7-14.

Montouris, G, Safety of newer antiepileptic drug oxcarbazepine during pregnancy, Current Medical Research and Opinion, Vol 21, Number 5, May 2005, p 693-701.

Shulman, L, Montouris, GD, Clinical Perspective in Women with Epilepsy, Clinical Guidelines, Supplement to The Female Patient, April, 2007, p. 5-12.

Montouris, GD, Jagoda, A, ”Management of Breakthrough Seizures in the Emergency Department: Continuity of Care, Current Medical Research and Opinion, Vol 23, No 7, 1583-1592.

Montouris, GD, “Seizures and Reproductive Health of Women”Primary Neuro News, Spring 2007, Vol 1, issue 2, pp 1-6.

Karamohamed S, Golbe LI, Mark MH, Lazzarini AM, Suchowersky O, Labelle N, Guttman M, Currie LJ, Wooten GF, Stacy M, Saint-Hilaire M, Feldman RG, Liu J, Shoemaker CM, Wilk JB, DeStefano AL, Latourelle JC, Xu G, Watts R, Growdon J, Lew M, Waters C, Vieregge P, Pramstaller PP, Klein C, Racette BA, Perlmutter JS, Parsian A, Singer C, Montgomery E, Baker K, Gusella JF, Herbert A, Myers RH. Absence of previously reported variants in the SCNA (G88C and G209A), NR4A2 (T291D and T245G) and the DJ-1 (T497C) genes in familial Parkinson’s disease from the GenePD study. Movement Disorders 2005; 20:1188-1191.

Karamohamed S, Latourelle JC, Racette BA, Perlmutter JS, Wooten GF, Lew MF, Klein C, Shill H, Golbe LI, Mark MH, Guttman M, Nicholson G, Wilk JB, Saint-Hilaire MH, DeStefano AL, Prakash R, Williamson S, Tobin J, Suchowersky O, Labelle N, Growdon JH, Singer C, Watts RL, Goldwurm S, Pezzoli G, Baker KB, Giroux ML, Pramstaller PP, Burn DJ, Chinnery PF, Sherman S, Vieregge P, Litvan I, Gusella JF, Myers RH, Parsian A. BDNF genetic variants are associated with onset-age of familial Parkinson’s disease: GenePD study. Neurology 2005; 65:1823-1825.

Seong IS, Ivanova E, Lee JM, Choo YS, Fossale E, Anderson M, Gusella JF, Laramie JM, Myers RH, Lesort M, Macdonald ME. The HD CAG Repeat Implicates a Dominant Property of Huntingtin in Mitochondrial Energy Metabolism. Human Molecular Genetics. 2005; 14:2871-2880.

Wilk JB, Myers RH, Pankow JS, Hunt SC, Leppert MF, Freedman BI, Province MA, Ellison RC. Adrenergic receptor polymorphisms associated with resting heart rate: The HyperGEN Study. Annals of Human Genetics 2006; 70:566-573.

Sun M, Latourelle JC, Wooten GF, Lew MF, Klein C, Shill HA, Golbe LI, Mark MH, Racette BA, Perlmutter JS, Parsian A, Guttman M, Nicholson G, Xu G, Wilk JB, Saint-Hilaire MH, DeStefano AL, Prakash R, Williamson S, Suchowersky O, Labelle N, Growdon JH, Singer C, Watts RL, Goldwurm S, Pezzoli G, Baker KB, Pramstaller PP, Burn DJ, Chinnery PF, Sherman S, Vieregge P, Litvan I, Gillis T, MacDonald ME, Myers RH, Gusella JF. Heterozygosity for Parkin Mutation Influences Onset Age in Familial Parkinson’s Disease: The GenePD Study. Archives of Neurology 2006;63:826-832.

Laramie JM, Wilk JB, Hunt SC, Ellison RC, Chakravarti A, Boerwinkle E, Myers RH. Evidence for a Gene Influencing Heart Rate on Chromosome 5p13-14 in a Meta-Analysis of Genome-Wide Scans from the NHLBI Family Blood Pressure Program. BMC Medical Genetics 2006; 7:17.

Myers RH. Considerations for Genomewide Association Studies in Parkinson Disease. (editorial). American Journal of Human Genetics 2006; 78:1081.

Lloret A, Dragileva E, Teed A, Espinola J, Fossale E, Gillis T, Lopez E, Myers RH, MacDonald ME, Wheeler VC. Genetic background modifies nuclear mutant huntingtin accumulation and HD CAG repeat instability in Huntington’s disease knock-in mice. Human Molecular Genetics 2006; 15:2015-2024.

Kishikawa S, Li J-L, Gillis T, Hakky MH, Warby S, Hayden M, MacDonald ME, Myers RH, Gusella JF. Brain-derived neurotrophic factor does not influence age at neurologic onset of Huntington’s disease. Neurobiology of Disease 2006; 24:280-285.

Li J-L, Hayden MR, Warby SC, Durr A, Morrison PJ, Nance M, Ross CA, Margolis RL, Rosenblatt A, Squitieri F, Frati L, Gomez-Tortosa E, Ayuso Garcia C, Suchowersky O, Klimek ML, Trent RA, McCusker E, Novelletto A, Frontali M, Paulsen JS, Jones R, Ashizawa T, Lazzarini A, Wheeler VC, Prakash R, Xu G, Djousse L, Mysore JS, Gillis T, Hakky M, Cupples LA, Saint-Hilaire MH, Cha J-HJ, Hersch SM, Penney JB, Harrison MB, Perlman SL, Zanko A, Abramson RK, Lechich AJ, Duckett A, Marder K, Conneally PM, Gusella JF, MacDonald ME, Myers RH. Genome-wide Significance for a Modifier of Age at Neurological Onset in Huntington Disease at 6q23-24: the HD MAPS Study. BMC Medical Genetics 2006, 7:71

Zeng W, Gillis T, Hakky M, Djousse L, Myers RH, MacDonald ME, Gusella JF. Genetic analysis of the GRIK2 modifier effect in Huntington’s disease. BMC Neuroscience 2006, 7:62.

Wilk JB, Tobin JE, Suchowersky O, Shill H, Klein C, Wooten GF, Lew M, Mark MH, Guttman M, Watts RL, Singer C, Growdon J, Latourelle JC, Saint-Hilaire M, DeStefano AL, Prakash R, Williamson S, Berg CJ, Sun M, Goldwurm S, Pezzoli G, Racette BA, Perlmutter JS, Parsian A, Baker K, Giroux ML, Litvan I, Pramstaller PP, Nicholson GA, Burn DJ, Chinnery PF, Vieregge P, Slevin JT, Cambi F, MacDonald ME, Gusella JF, Myers RH, Golbe LI. Herbicide exposure modifies GSTP1 haplotype association to Parkinson onset age: The GenePD Study. Neurology 2006; 67:2206-2210.

Feitosa MF, Province MA, Heiss G, Arnett DK, Myers RH, Pankow JS, Hopkins PN, Borecki IB. Evidence of QTL on 15q21 for High-Density Lipoprotein Cholesterol: The National Heart, Lung, and Blood Institute Family Heart Study. Atherosclerosis 2007;190:232-237

Tobin JE, Cui J, Wilk JB, Latourelle JC, Laramie JM, McKee AC, Guttman M, Karamohamed S, DeStefano AL, Myers, RH. Sepiapterin reductase expression is increased in Parkinson’s disease brain tissue. Brain Research 2007; 1139:42-47.

Nair A, Boeve BF, Edland SD, Jack CR, Slusser TC, Knopman DS, Petersen RC. Hippocampal Asymmetry Predicts Neuropsychological Performance in Alzheimer’s Disease. Abstract presented at American Academy of Neurology, Mayo Clinic, Rochester, MN, April 29 2004.

Nair A, Boeve BF, Smith GE, Ivnik RJ , Knopman DS, Hutton ML, Baker MC, Edland SC, Kuntz K, Petersen RC, Neuropsychological Findings in Mild Frontotemporal Dementia Associated With Tau Mutations. Presented at 9th International Conference on Alzheimer’s Disease and Related Disorders, Philadelphia, PA, USA, July 17-22, 2004.

Widdess-Walsh P, Nair A, Staugaitis SM. Primary CNS lymphoma (Diffuse large B-cell lymphoma). Brain Pathology. October 2004

Boeve BF, Tremont-Lukats IW, Waclawik AJ, Murrell JR, Hermann B, Jack CR Jr, Shiung MM, Smith GE, Nair A, Lindor N, Koppikar V, Ghetti B. Longitudinal characterization of two siblings with frontotemporal dementia and parkinsonism linked to chromosome 17 associated with the S305N tau mutation. Brain. 2004 Dec 22; [Epub ahead of print]

Boeve BF, Tremont-Lukats IW, Waclawik AJ, Murrell JR, Hermann B, Jack CR Jr, Shiung MM, Smith GE, Nair A, Lindor N, Koppikar V, Ghetti B. Longitudinal characterization of two siblings with frontotemporal dementia and parkinsonism linked to chromosome 17 associated with the S305N tau mutation. Brain. 2005 Apr;128(Pt 4):752-72.

Baker M, Dickson DW, Lin W, DeLucia M, Kumar N, Hutton M, Ellison J, Fredericks GV, Duffy J, Woodruff BK, Nair AK, Kuntz K, Jack CR, Westmoreland BF, Boeve BF. Characterization of a Kindred with a Novel Twelve Octapeptide Repeat Insertion in the Prion Protein Gene. Article submitted for publication.

Boeve B, Shiung M, Jack C, Knopman D, Smith G, Ivnik R, Nair A, Lewis J, Hutton M, Wszolek Z, Murrell J, Waclawik A, Koppikar V , Kodras R, Duff K , Kuntz K, Ghetti B, Petersen R. Changes in the Rate of Functional, Clinical, and Radiologic Progression in FTDP-17 Associated With Lithium Administration. Article submitted for publication.

Nair A, Green RC: Alzheimer’s disease at 100 years. Practical Neurology, in press. [PDF]

Au R, Seshadri S, Wolf PA, Sullivan L, D’Agostino RB. New Norms for a new generation: cognitive performance in the Framingham Offspring Cohort. Experimental Aging Research 2004;30: 333-358.

Elias MF, Sullivan LM, D’Agostino RB, Elias PK, Beiser A, Au R, Seshadri S, DeCarli C, Wolf PA. Framingham Stroke Risk Profile and Lowered Cognitive Performance. Stroke 2004;35: 404-409.

Jeerakathil T, Wolf PA, Beiser A, Massaro J, Seshadri S, D’Agostino RB, DeCarli C. Stroke risk profile predicts white matter hyperintensity volume: the Framingham Study. Stroke 2004;35: 1857-61.

Ivan CS, Seshadri S, Beiser A, Au R, Kase CS, Kelly-Hayes M, Wolf PA. Dementia after stroke: The Framingham Study. Stroke 2004;35: 1264-69.

Zaldy ST, Seshadri S, Beiser A, et al. Bone mineral disease and the risk of Alzheimer’s disease. Arch Neurol 2005;62: 107-111.

Ellias MF, Sullivan LM, D’Agostino RB, Elias PK, Jacques PF, Selhub J, Seshadri S, Au R, Beiser A, Wolf PA. Homocysteine and cognitive performance in the Framingham Offspring Study: age is important. Am J Epidemiol 2005;162:644-53.

Seshadri S, Beiser A, et al. Lifetime risk of stroke and dementia. Stroke 2006; 37(2):345-50.

Seshadri S. Elevated plasma homocysteine levels: risk factor or risk marker for the development of dementia and Alzheimer’s disease? J Alz Dis 2006;9:393-8.

Elias MF, Sullivan LM, Elias PK, Vasan RS, D’Agostino RB, Seshadri S, Au R, Wolf PA, Benjamin EJ. Atrial fibrillation is associated with lower cognitive performance in the Framingham Offspring men. Journal of Stroke and Cerebrovascular Diseases 2006;15:214-222.

Seshadri S. Methodology for measuring cerebrovascular disease burden. Int Rev Psych 2006;37:345-50.

Seshadri S, Wolf PA, Besier A, Elias MF, Au R, Kase CS, D’Agostino RB, DeCarli C. Stroke Risk Profile, Brain Volume and Cognitive Function: The Framingham Offspring Study. Neurology 2004;63: 1591-99. Akomolafe A, Beiser AS, Meigs JB, Au R, Green RC, Farrer LA, Wolf PA, Seshadri S. Diabetes mellitus and risk of developing Alzheimer’s dementia: results from the Framingham Study. Arch Neurol 2006; 63:1551-5.

Carandang R, Seshadri S, Beiser A, Kelly-Hayes M, Kase CS, Kannel WB, Wolf PA. Temporal trends in incidence, lifetime risk, severity and mortality of stroke over the past fifty years. JAMA 2006;296:2939-46.

Au R, Massaro JM, Wolf PA, Young ME. Beiser AS, Seshadri S, D’Agostino RB, DeCarli C. Association of white matter hyperintensity volume with cognitive functioning- The Framingham Heart Study. Arch Neurol 2006;63:246-250.

McKee AC, Au R, Cabral HJ, Kowall NW, Seshadri S, Kubilus CA, Drake J, Drake BS, Wolf PA. Pathological involvement of the visual association cortex in cognitively intact, mildly impaired and demented subjects with Alzheimer’s Disease. Neuropathol Exp Neurol. 2006;65:621-30.

Tan ZS, Beiser AS, Vasan RS, Roubenoff R, Dinarello CA, Harris TB, Benjamin EJ, Au R, Kiel DP, Wolf PA, Seshadri S. Inflammatory markers and the risk of Alzheimer’s disease: The Framingham Study. Neurology 2007;68:1902-1908.

Wolf PA, Beiser A, Elias MF, Au R, Vasan RS, Seshadri S. Relation of Obesity to Cognitive Function: Importance of Central Obesity and Synergistic Influence of Concomitant Hypertension. The Framingham Heart study. Current Alzheimer Research 2007;4:111-116.

MF Elias, LM Sullivan, EJ. Benjamin, PK Elias, RB D’Agostino, Sr., PA Wolf, Seshadri S, Au R, Vasan RS. Left Ventricular Mass, Blood Pressure and Lowered Cognitive Performance in the Framingham Offspring. Hypertension. 2007;49:439-45.

Jefferson AL, Massaro JM, Wolf PA, Seshadri S, Au R, Vasan R, Larson MG, Meigs JB, Keaney JF, Lipinska I, Kathiresan S, Benjamin EJ, DeCarli C.Inflammatory Biomarkers are Associated with Total Brain Volume: The Framingham Heart Study. Neurology 2007;68:1032-1038.

Seshadri S, Wolf PA. Lifetime Risk of Stroke. Lancet Neurology [in press].

Seshadri S, DeStefano AL, Au R, Massaro JM, Beiser AS, Kelly-Hayes M, Kase CS, D’Agostino RB Sr., DeCarli C, Atwood LD, Wolf PA. Genetic correlates of brain aging on MRI and cognitive test measures: a genome wide association and linkage analysis in the Framingham study. BMC Genetics [in press].

Temple, R.O. Stern, R.A., Latham, J., Ruffolo, J.S., Arruda, J.E. & Tremont, G. (2004). Assessment of Mood State in Dementia by Use of the Visual Analog Mood Scales (VAMS). American Journal of Geriatric Psychiatry, 12. 527-530.

Stern, R.A., Davis, J.D., Rogers, B.L., Smith, K.M., Harrington, C.J., Ott, B.R., Jackson, I.M.D., & Prange, A.J. Jr. (2004). Preliminary study of the relationship between thyroid status and cognitive and neuropsychiatric functioning in euthyroid patients with Alzheimer’s dementia. Cognitive and Behavioral Neurology, 17, 219-223.

Brown, L.B., Stern, R.A., Cahn-Weiner, D.A., Rogers, B., Davis, M.A., Lannon, M.C., Maxwell, C., Souza, T., White, T., & Ott, B.R. (2005). Driving Scenes test of the Neuropsychological Assessment Battery (NAB) and on-road driving performance in aging and very mild dementia. Archives of Clinical Neuropsychology, 20, 209-215.

Jefferson, A.L., Wong, S., Bolen, E., Ozonoff, A., Green, R.C., & Stern, R.A. (2006). Cognitive correlates of HVOT performance differ between patients with mild cognitive impairment and normal controls. Archives of Clinical Neuropsychology, 21, 405-412.

Westervelt, H.J., Brown, L.B, Tremont, G., Javorsky, D.J., & Stern, R.A. (2006). Patient and family perceptions of the neuropsychological evaluation: How Are We Doing? The Clinical Neuropsychologist, . 1385-4046

Bhalla, R.K., Papandonatos, G.D., Stern, R.A., & Ott, B.R. (2007). Alzheimer’s disease patients’ anxiety prior to and following a standardized on-road driving test. Alzheimer’s and Dementia, 3, 33-39.

Ropacki, S.A.L., Bert, A.A., Ropacki, M.T., Rogers, B.L., & Stern, R.A. (2007). The influence of cognitive reserve on neuropsychological functioning after coronary artery bypass grafting (CABG). Archives of Clinical Neuropsychology,.22, 73-85.

Jefferson, A.L., Wong, S., Gracer, T.S. Ozonoff, A., Green, R.C., & Stern, R.A. (in press). Geriatric norms for an abbreviated version of the Boston Naming Test. Applied Neuropsychology.

Posternak, M.A., Novak, S.P., Stern, R.A., Hennessey, J.V., Joffe, R., Prange, A.J. Jr, & Zimmerman, M. (in press). A pilot effectiveness study: placebo-controlled trial of adjunctive L-triiodothyronine (T3) used to accelerate and potentiate the antidepressant response. The International Journal of Neuropsychopharmacology.

Viereck J., F.L. Ruberg, Y. Qiao, A.S. Perez, K. Detwiller, M. Johnstone, and J.A. Hamilton (2005). MRI of Atherothrombosis Associated With Plaque Rupture. Arteriosclerosis, Thrombosis, and Vascular Biology, 25:240-245.

Kahn, J.H., J. Viereck, C. Kase, T. Jeerakathil, R. Romero, S.D. Mehta, R. Kociol, and V. Babikian (2005). The use of intravenous recombinant tissue plasminogen activator in acute ischemic stroke. Journal of Emergency Medicine, 29:273-277.

Ruberg F.L.,J. Viereck, A. Phinikaridou, Y. Qiao, J. Loscalzo, and J.A. Hamilton (2006). Identification of cholesteryl esters in human carotid atherosclerosis by ex vivo image-guided proton MRS. Journal of Lipid Research, 47(2):310-7.

Ziouzenkova O., G. Orasanu, M. Sharlach, T.E. Akiyama, J.P. Berger, J. Viereck, J.A. Hamilton, G. Tang, G.G. Dolnikowski, S. Vogel, G. Duester and J. Plutzky (2007). Retinaldehyde represses adipogenesis and diet-induced obesity. Nature Medicine, in press.

Qiao Y., I. Ronen, J. Viereck, F.L. Ruberg, and J.A. Hamilton (2007). Identification of Atherosclerotic Lipid Deposits by Diffusion Weighted Imaging. Arteriosclerosis, Thrombosis, and Vascular Biology, 27:1440-1446.

Michaelides, C., and Wiesman, J., Letter to the Editor: Subacute Combined Degeneration of the Spinal Cord in a Young African-American Male, Southern Medical Journal, Vol 99 (1); 1311, 2006

Berk JL, Wiesman JF, Skinner M, Sanchorawala V. Diaphragm paralysis in primary systemic amyloidosis. Amyloid. 2005 Sep;12(3):193-6.

Skinner, M, et al. “High-Dose Melphalan and Autologous Stem-Cell Transplantation in Patients with AL Amyloidosis: An 8-Year Study. Annals of Internal Medicine 2004; 140:85.

Wiesman, J. “Overview of Overactive Bladder”, an article review, Journal Watch, May, 2004.

Elias MF, Sullivan LM, D’Agostino RB, Elias PK, Beiser A, Au, R, Seshadri S, DeCarli C, Wolf PA. The Framingham Stroke Risk Profile and Lowered Cognitive Performance. Stroke 2004,35(2):404-409. [PMID: 14726556],

Massaro JM, D’Agostino RB, Sullivan LM, Beiser A, DeCarli C, Au R, Elias MF, Wolf PA. Managing and Analysing Data From a Large-Scale Study on Framingham Offspring Relating Brain Structure to Cognitive Function. Stat Med 2004;23(2):351-367. [PMID: 14716734]

Wang TJ, Larson MG, Levy D, Benjamin EJ, Leip EP, Omland T, Wolf PA, Vasan RS. Plasma Natriuretic Peptide Levels and the Risk of Cardiovascular Events and Death. N Engl J Med 2004;350(7):655-663. [PMID: 14960742],

Millen BE, Quatromoni PA, Nam B-H, O’Horo CE, Polak JF, Wolf PA, D’Agostino RB. Dietary Patterns, Smoking, and Subclinical Heart Disease in Women: Opportunities for Primary Prevention from the Framingham Nutrition Studies. J Am Diet Assn 2004;104(2);208-214. [PMID: 14760568]

Janardhan V, Wolf PA, Kase CS, Massaro JM, D’Agostino RB, Franzblau C, Wilson PWF. Anticardiolipin Antibodies and the Risk of Ischemic Stroke and Transient Ischemic Attack: The Framingham Cohort and Offspring Study. Stroke 2004;35(3):736-741. [PMID: 14764933],

Fox CS, Larson MG, Corey D, Feng D, Lindpaintner K, Polak JF, Wolf PA, D’Agostino RB, Tofler GH, O’Donnell CJ. Absence of Association Between Polymorphisms in the Hemostatic Factor Pathway Genes and Carotid Intimal Medial Thickness: The Framingham Heart Study. Stroke 2004, 35:e65-e67. [PMID: 14963283]

Fox CS, Cupples LA, Chazaro I, Polak JF, Wolf PA, D’Agostino RB, Ordovas JM, O’Donnell CJ. Genomewide Linkage Analysis for Internal Carotid Artery Intimal Medial Thickness: Evidence for Linkage to Chromosome 12. Am J Hum Genet 2004, 74(2):253-261. Erratum in: Am J Hum Genet 2004, 74(5):1080. [PMID: 14730480]

Djoussé L, Levy D, Benjamin EJ, Blease SJ, Russ A, Larson MG, Massaro JM, D’Agostino RB, Wolf PA, Ellison RC. Long-term Alcohol Consumption and the Risk of Atrial Fibrillation in the Framingham Study. Am J Cardiol 2004;93(6):710-713. [PMID: 15019874]

Ivan CS, Seshadri S, Beiser A, Au R, Kase CS, Wolf PA. Dementia After Stroke: The Framingham Study. Stroke 2004;35(6):1264-1269. [PMID: 15118167]

Fox CS, Parise H, D’Agostino RB, Lloyd-Jones D, Vasan RS, Wang TJ, Levy D, Wolf PA, Benjamin EJ. Parental Atrial Fibrillation as a Risk Factor for Atrial Fibrillation in Offspring. JAMA 2004;291(23):2851-2855. [PMID: 15199036]

Jeerakathil T, Wolf PA, Beiser A, Hald JK, Au R, Kase CS, Massaro JM, DeCarli C. Cerebral Microbleeds. Prevalence and Associations with Cardiovascular Risk Factors in the Framingham Study. Stroke 2004;35(8):1831-1835. [PMID: 15155954]

Jeerakathil T, Wolf PA, Beiser A, Massaro J. Stroke Risk Profile Predicts White Matter Hyperintensity Volume: The Framingham Study. Stroke 2004;35(8):1857-1861. [PMID: 15218158]

Atwood LD, Wolf PA, Heard-Costa NL, Massaro J, Beiser A, D’Agostino RB, DeCarli C. Genetic Variation in White Matter Hyperintensity Volume in the Framingham Study. Stroke 2004;35(7):1609-1613. [PMID: 15143299]

Au R, Wolf PA, Beiser A, Seshadri S. New Norms for a New Generation: Cognitive Performance in the Framingham Offspring Cohort. Exp Aging Res 2004;30(4):333-358. [PMID: 15371099]

Seshadri S, Wolf PA, Beiser A, Elias MF, Au R, Kase CS, D’Agostino R, DeCarli C. Stroke Risk Profile, Brain Volume and Cognitive Function: The Framingham Offspring Study. Neurology 2004;63(9):1591-1599. [PMID: 15534241]

Seshadri S, Beiser A, Ivan CS, Au R, Kase CS, Kelly-Hayes M, Wolf PA. Letter to the Editor, Response. Does Preventing Stroke Prevent All Kinds of Dementia? Stroke 2004;35(11):2436-2437. [PMID: 15486325]

Wang TJ, Parise H, Levy D, D’Agostino RB,Sr, Wolf PA, Vasan RS, Benjamin EJ. Obesity and the Risk of New-Onset Atrial Fibrillation: The Framingham Heart Study. JAMA 2004;292(20):2471-2477. [PMID: 15562125]

DeCarli C, Atwood LD, Wolf PA. Letter to the Editor, Response. White Matter Hyperintensities: Pearls and Pitfalls in Interpretation of MRI Abnormalities. Stroke 2004;35:2756-2757. [PMID: 15528462]

Elosua R, Ordovas JM, Cupples LA, Fox CS, Polak JF, Wolf PA, D’Agostino Sr RA, O’Donnell CJ. Association of APOE Genotype with Carotid Atherosclerosis in Men and Women: The Framingham Heart Study. J Lipid Res 2004;45(10):1868-1875. [PMID: 15258198]

Sam C, Massaro JM, D’Agostino RB Sr, Levy D, Lambert JW, Wolf PA, Benjamin EJ. Warfarin and Aspirin Use and the Predictors of Major Bleeding Complication in Atrial Fibrillation (the Framingham Heart Study). Am J Cardiol 2004;94(7):947-951 [PMID: 15464686].

Lloyd-Jones, DM, Wang TJ, Leip EP, Larson MG, Levy D, Vasan RS, D’Agostino RB, Massaro JM, Beiser A, Wolf PA, Benjamin EJ. Lifetime Risk for Development of Atrial Fibrillation: The Framingham Heart Study. Circulation 2004, 110:1042-1046. [PMID: 15313941].

Wang TJ, Parise H, Sullivan LM, D’Agostino RB, Sr, Levy D. Wolf PA, Benjamin EJ. Reply to Letter to the Editor Obesity and the Risk of New-Onset Atrial Fibrillation. . JAMA 2005; 293(16):1974-1975.,

DeCarli C, Massaro J, Harvey D, Hald J, Tullberg M, Au R, Beiser A, D’Agostino R, Wolf PA. Measures of Brain Morphology and Infarction in the Framingham Heart Study: Establishing What Is Normal. Neurobiol Aging 2005;26(4):491-510. [PMID: 15653178]

Tan ZS, Seshadri S, Beiser A, Zhang Y, Felson D, Hannan MT, Au R, Wolf PA, Kiel DP. Bone Mineral Density and the Risk of Alzheimer’s Disease. Arch Neurol 2005;62(1):107-111. [PMID: 15642856],

Elias PK, Elias MF, D’Agostino RB, Sullivan LM, Wolf PA Serum Cholesterol and Cognitive Performance in the Framingham Heart Study. Psychosom Med 2005;67(1):24-30. [PMID: 15673620],

Radziszewska B., Hart RG, Wolf PA, D’Agostino RB, Sr., Cutler JA. Clinical Research in Primary Stroke Prevention: Needs, Opportunities, and Challenges. Neuroepidemiology. 2005;25(2):91-104. [PMID: 15956806]

Elias MF, Sullivan LM, D’Agostino RB, Elias PK, Jacques PF, Selhub J, Seshadri S, Au R, Beiser A, Wolf PA. Homocysteine and Cognitive Performance in the Framingham Offspring Study: Age is Important. Am J Epidemiol 2005;162(1):644-653. [PMID: 16107567]

Terry DF, Pencina M, Vasan RS, Murabito JM, Wolf PA, Kelly-Hayes M, Levy D, D’Agostino RB, Sr,. Benjamin E. Cardiovascular Risk Factors Predictive for Survival and Morbidity-Free Survival in the Oldest Old Framingham Heart Study Participants. J Am Geriatr Soc 2005; 53(11):1944-1950. [PMID 16274376]

Lessov-Schlaggar CN, Reed T, Swan GE, Krasnow RE, DeCarli C, Marcus R, Holloway L, Wolf PA, Carmelli D. Association of Sex Steroid Hormones with Brain Morphology and Cognition in Healthy Elderly Men. Neurology, 2005;65(10):1591-1596. [PMID: 16301487]

Elias MF, Elias PK, Sullivan LM, Wolf PA, D’Agostino RB. Obesity, Diabetes and Cognitive Deficit: The Framingham Study. Neurobiol Aging, 2005;26S1:S11-S16. [PMID: 16223549]

Babikian VL, Wolf PA. Invited Letter to the Editor. Retinal and Cerebral Microembolism During On-Pump and Off-Pump Coronary Artery Bypass Graft Surgery. Circulation 2005;112(25):3816-3817. [PMID: 16365204]

DeStefano AL, Atwood L, Massaro JM, Heard-Costa N, Beiser A, Au R, Wolf P, DeCarli C. Genome-wide Scan for White Matter Hyperintensity: The Framingham Heart Study. Stroke 2006;37(1):77-81 [PMID: 16322484].

Najarian RM, Sullivan LM, Kannel WB, Wilson PF, D’Agostino RB, Wolf PA. Metabolic Syndrome Compared with Type 2 Diabetes Mellitus as a Risk Factor for Stroke: The Framingham Study. Arch Intern Med 2006;166(1):106-111. [PMID 16401818]

Seshadri S, Beiser A, Kelly-Hayes M, Kase CS, Au R, Wolf PA. The Lifetime Risk of Stroke: Estimates from the Framingham Study. Stroke 2006, 37(2):345-350. [PMID: 16397184]

Au R, Massaro JM, Wolf PA, Young ME, Beiser A, Seshadri S, D’Agostino RB, DeCarli C. Association of White Matter Hyperintensity Volume with Decreased Cognitive Functioning: The Framingham Heart Study. Arch Neurol, 2006;63(2):246-250. [PMID: 16476813]

Lloyd-Jones D, Leip EP, Larson MG, D’Agostino RB, Beiser A, Wilson PWF, Wolf PA, Levy D. Prediction of Lifetime Risk for Cardiovascular Disease by Risk Factor Burden at 50 Years of Age. Circulation 2006;113(6):791-798. [PMID: 16461820]

Elosua R, Ordovas JM, Cupples LA, Lai CQ, Demissie S, Fox CS, Polak JF, Wolf PA, D’Agostino RB, O’Donnell CJ. Variants at the APOA5 Locus, Association with Carotid Atherosclerosis and Modification by Obesity: The Framingham Study. J Lipid Res 2006;47(5):990-996. [PMID: 16474174]

Najarian RM, Sullivan LM, Kannel WB, Wilson PWF, D’Agostino RB, Wolf PA. Reply to Letter to the Editor. Stroke, Obstructive Sleep Apnea, and Disorders of Glucose Metabolism. Arch Intern Med 2006;166:1418-1419.

McKee AC, Au R, Cabral HJ, Kowall NW, Seshadri S, Kubilus CA, Drake J, Wolf PA. Visual Association Pathology in Preclinical Alzheimer Disease. J Neuropathol Exp Neurol 2006;65;(6):621-630. [PMID: 16783172]

Elias MF, Sullivan LM, Elias PK, Vasan RS, D’Agostino RB Sr., Seshadri S, Au R, Wolf PA, Benjamin EJ. Atrial Fibrillation Is Associated With Lower Cognitive Performance in the Framingham Offspring Men. J Stroke and Cerebrovascular Disease, 2006;15 (5):214-222.

Elosua R, Cupples LA, Fox CS, Polak JF, D’Agostino RB, Wolf PA, O’Donnell CJ, Ordovas JM. Association Between Well-Characterized Lipoprotein-Related Genetic Variants and Carotid Intimal Medial Thickness and Stenosis: The Framingham Heart Study. Atherosclerosis 2006;189(1):222-228. [PMID: 16430904]

Schaefer EJ, Bongard V, Beiser A, Lamon-Fava S, Au R, Tucker KL, Kyle D, Wilson PWF, Wolf PA. Plasma Phosphotidylcholine Docosahexaenoic AcidContent and Risk of Dementia and Alzheimer Disease: The Framingham Heart Study. Arch Neurol 2006;63:1545-1550. [PMID: 17101822]

Akomolafe A, Beiser A, Meigs J, Au R, Green RC, Farrer LA, Wolf PA, Seshadri S. Diabetes Mellitus and Risk of Developing Alzheimer’s Dementia: Results from the Framingham Study. Arch Neurol 2006;63:1551-1555. [PMID: 17101823]

Carandang R, Seshadri S, Beiser A, Kelly-Hayes M , Kase CS, Kannel WB, Wolf PA. Trends in Incidence, Lifetime Risk, Severity, and 30-day Mortality of Stroke Over the Past 50 Years: The Framingham Study. JAMA 2006;296;24:2939-2946. [PMID: 17190894]

Lessov-Schlaggar CN, Swan GE, Reed T, Wolf PA, Carmelli D. Longitudinal Genetic Analysis of Executive Function in Elderly Men. Neurobiol Aging 2006; Sep 9. [PMID: 16965841]

Wolf PA. Lipids and Ischemic Stroke. Journal Watch 2007;9:1;1-2.

Salaycik KJ, Kelly-Hayes M, Beiser A, Nguyen A-H, Brady SM, Kase CS, Wolf PA. Depressive Symptoms and Risk of Stroke: The Framingham Study. Stroke 2007;38:16-21. [PMID: 17138952]

Kathiresan S, Larson MG, Keyes MJ, Polak JF, Wolf PA, D’Agostino RB, Jaffer FA, Clouse ME, Levy D, Manning WJ, O’Donnell CJ. Assessment by Cardiovascular Magnetic Resonance, Electron Beam Computed tomography, and Carotid Ultrasonography of the distribution of Subclinical Atherosclerosis Across Framingham Risk Strata. Am J Cardiol 2007;99(3):310-314. [PMID: 17261388]

Elias MF, Sullivan LM, Elias Pk, D’Agostino Sr RB, Wolf PA, Seshadri S, Au R, Benjamin EJ, Vasan RJ. Left Ventricular Mass, Blood Pressure, and Lowered Cognitive Performance in the Framingham Offspring. Hypertension, March 2007;49:439-445. [PMID 17224472]

Jefferson AL, Massaro JM, Wolf PA, Seshadri S, Au R, Vasan RS, Larson MG, Meigs JB, Keaney JF, Lipinska I, Kathiresan S, Benjamin EJ, DeCarli C. Inflammatory Biomarkers Are Associated with Total Brain Volume: The Framingham Heart Study. Neurology 2007;68:1032-1038 [PMID: 17389308].

Wolf PA, Beiser A, Elias MF, Au R, Vasan RS, Seshadri S. Relation of Obesity to Cognitive Function: Importance of Central Obesity and Synergistic Influence of Concomitant Hypertension. The Framingham Heart Study. Curr Alzheimer Res 2007;4;2:111-116. [PMID: 17430232]

Terry DF, Evans JC, Pencina MJ, Murabito JM, Vasan RS, Wolf PA, Kelly-Hayes M, Levy D, D’Agostino Sr. RB, Benjamin EJ. Characteristics of Framingham Offspring Participants With Long-Lived Parents. Arch Intern Med 2007;167:438-444. [PMID: 17353490]

Splansky GL, Corey D, Yang Q, Atwood LD, Cupples LA, Benjamin EJ, D’Agostino Sr. RB, Fox CS, Larson MG, Murabito JM, O’Donnell CJ, Vasan RS, Wolf PA, Levy D. The Third Generation Cohort of the National Heart, Lung and Blood Institute’s Framingham Heart Study: Design, Recruitment and Initial Examination. Am J Epidemiol 2007;165:1328-1335. [PMID: 17372189]

Ingelsson E, Sullivan LM, Murabito JM, Fox CS, Benjamin EJ, Polak JF, Meigs JB, Keyes MJ, O’Donnell CJ, Wang TJ, D’Agostino Sr. RB, Wolf PA, Vasan RS. Prevalence and Prognostic Impact of Subclinical Cardiovascular Disease in Individuals with the Metabolic Syndrome and Diabetes. Diabetes 2007;56:1718-1726. PMID: 17369522].

Tan ZS, Beiser AS, Vasan RS, Roubenoff R, Dinarello CA, Harris TB, Benjamin EJ, Au R, Kiel DP, Wolf PA, Seshadri S. Inflammatory Markers and the Risk of Alzheimer Disease: The Framingham Study. Neurology 2007;68:1902-1908.

Kelly-Hayes M, Wolf PA. Response to Letter by Salvador Vale, M.D. to the Editor on Depressive Symptoms and Risk of Stroke: The Framingham Study. Stroke June, 2007;38:e35.

Carandang R, Seshadri S, Beiser A, Kelly-Hayes M, Kase CS, Kannel WB, Wolf PA. Trends in Stroke Over the Past 50 Years. Cardiology Review, August, 2007.