Selected Faculty Publications

Below are selected publications of faculty in the Department of Neurology:
Debette S, Beiser A, DeCarli C, Au R, Himali JJ, Kelly-Hayes M, Romero JR, Kase CS, Wolf PA, Seshadri S. Association of MRI markers of vascular brain injury with incident stroke, mild cognitive impairment, dementia, and mortality: The Framingham Offspring Study. Stroke 41: 600-606, 2010.

Rist PM, Berger K, Buring JE, Kase CS, Gaziano JM, Kurth T. Alcohol consumption and functional outcome after stroke in men. Stroke 41:141-146, 2010.

Kase CS, Albers GW, Bladin C, Fieschi C, Gabbai AA, O’Riordan W, Pineo GF, on behalf of the PREVAIL Investigators. Neurological outcomes in patients with ischemic stroke receiving enoxaparin or heparin for venous thromboembolism prophylaxis: subanalysis of the Prevention of VTE after Acute Ischemic Stroke With LMWH (PREVAIL) study. Stroke 40:3532-3240, 2009.

Karakis I, MacDonald JA, Stefanidou M, Kase CS. Clinical and radiological features of brainstem variant of hypertensive encephalopathy. Journal of Vascular and Interventional Neurology 2:172-176, 2009.

Sherman DG, Albers GW, Bladin C, Fieschi C, Gabbai AA, Kase CS, O’Riordan W, Pineo GF, for the PREVAIL Investigators. The efficacy and safety of enoxaparin versus unfractionated heparin for the prevention of venous thromboembolism after acute ischaemic stroke (PREVAIL study): An open-label randomized comparison. Lancet 369:1347-1355, 2007.

Aguilar MI, Hart RG, Kase CS, Freeman WD, Hoeben BJ, Garcia RC, Ansell JE, Mayer SA, Norrving B, Rosand J, Steiner T, Wijdicks EFM, Yamaguchi T, Yasaka M. Treatment of warfarin-associated intracerebral hemorrhage: Literature review and expert opinion. Mayo Clinic Proceedings 82:82-92, 2007.

Salaycik KJ, Kelly-Hayes M, Beiser A, Nguyen A-H, Brady SM, Kase CS, Wolf PA. Depressive symptoms and risk of stroke: The Framingham Study. Stroke 38: 16-21, 2007.

Kurth T, Everett BM, Buring JE, Kase CS, Ridker PM, Gaziano JM. Lipid levels and the risk of stroke in women. Neurology 68:556-562, 2007.

Broderick J, Connolly S, Feldmann E, Hanley D, Kase CS, Krieger D, Mayberg M, Morgenstern L, Ogilvy CS, Vespa P, Zuccarello M. Guidelines for the management of spontaneous intracerebral hemorrhage in adults: 2007. Stroke 38:2001-2023, 2007.

Seshadri S, Beiser A, Kelly-Hayes M, Kase CS, Au R, Kannel WB, Wolf PA. The lifetime risk of stroke: estimates from the Framingham Study. Stroke 37: 345-350, 2006.

Juvela S, Kase CS,. Advances in intracerebral hemorrhage management. Stroke 37: 301-304, 2006.

Kurth T, Moore SC, Gaziano JM, Kase CS, Stampfer MJ, Berger K, Buring JE. Healthy lifestyle and the risk of stroke in women. Archives of Internal Medicine 166:1403-1409, 2006.

Bowman TS, Kurth T, Kase CS, Sesso HD, Gaziano JM. Blood pressure measures and risk of total, ischemic and hemorrhagic stroke in men. Neurology 67: 820-823, 2006.

Carandang R, Seshadri S, Beiser A, Kelly-Hayes M, Kase CS, Kannel WB, Wolf PA. Temporal trends in incidence, lifetime risk, severity and mortality of stroke over the past fifty years: The Framingham Study. Journal of the American Medical Association 296: 2939-2946, 2006.

Aurora RN, Zak RS, Maganti RK, Auerbach SH, Casey KR, Chowdhuri S, Karippot A, Ramar K, Kristo DA, Morgenthaler TI; Standards of Practice Committee; American Academy of Sleep Medicine. Best practice guide for the treatment of REM sleep behavior disorder (RBD) J Clin Sleep Med. 2010 Feb 15;6(1):85-95. Erratum in: J Clin Sleep Med. 2010 Apr 15;6(2):

McNamara, P., Auerbach, S., Johnson, P., Harris, E., & Doros, G. Impact of REM sleep on distortions of self concept, mood and memory in depressed/anxious participants. Journal of Affective Disorders, 2010 May;122(3):198-207.

Brass S, Auerbach S, Sleep Disorders in Patients With Multiple Sclerosis: A Review. Sleep Med Rev. 2010 Apr;14(2):121-9.

Huang, MP, Radadia, K, Racone, BW, Auerbach, SH, Datta, S. Effects of eszopiclone and zolpidem on sleep–wake behavior, anxiety-like behavior and contextual memory in rats. Behavioral Brain Research. (2010). Jun 26;210(1):54-66.

Saczynski JS, Beiser A, Seshadri S, Auerbach S, Wolf P, Au R. Depressive symptoms and risk of dementia The Framingham Heart Study. Neurology 2010;75:35–41

Aurora RN, Zak RS, Auerbach SH, Casey KR, Chowdhuri S, Karippot A, Maganti RK, Ramar K, Kristo DA, Bista SR, Lamm CI, Morgenthaler TI; Best practice guide for the treatment of nightmare disorder in adults. J Clin Sleep Med. 2010 Aug 15;6(4):389-401.

Aurora, RN, Casey, KR, Kristo, D, Auerbach, SH, Maganti, RK, Bista, SR, Chowdhuri, S, Karippot, A, Lamm, CI, Ramar, K, Zak, RS, Morgenthaler, TI. Practice Parameters for the Surgical Modifications of the Upper Airway for Obstructive Sleep Apnea in Adults. Sleep. 2010;33(10):1408-1413.

Lieb,W, Beiser, AS, Vasan,RS; Tan, ZS; Au,R ; Harris,TB ; Roubenoff,R; Auerbach, S; DeCarli,C; Wolf,PA; Seshadri,S. Serum Leptin Levels Predict Incident Alzheimer’s Disease and MRI Measures Of Brain Aging: The Framingham Study. JAMA. 2009;302(23):2565-2572

Stavitsky, K., McNamara, P., Durso, R., Harris, E., Auerbach, S. and Cronin-Golomb, A. (2008) Hallucinations, dreaming and frequent dozing in Parkinson’s disease: Impact of right-hemisphere neural networks. Cognitive and Behavioral Neurology, Sep;21(3):143-9.

Datta S, Li G, Auerbach S. Activation of phasic pontine-wave generator in the rat: a mechanism for expression of plasticity-related genes and proteins in the dorsal hippocampus and amygdale. European Journal of Neuroscience, Vol. 27, pp. 1876–1892, 2008.

Outcome improvement in acute stroke revascularization procedures. Babikian VL, Nguyen TN. Stroke. 2010 Apr;41(4):577-8. Epub 2010 Feb 18.

Microemboli are not associated with delirium after coronary artery bypass graft surgery. Rudolph JL, Babikian VL, Treanor P, Pochay VE, Wigginton JB, Crittenden MD, Marcantonio ER.
Perfusion. 2009 Nov;24(6):409-15.

Balloon angioplasty of the A2 segment of the anterior cerebral artery for recurrent, symptomatic atherosclerotic disease. Karakis I, Nguyen TN, Babikian VL, Norbash AM. J Neurosurg. 2010 Mar;112(3):582-4.

Cerebral hemodynamics during coronary artery bypass graft surgery: the effect of carotid stenosis. Rudolph JL, Sorond FA, Pochay VE, Haime M, Treanor P, Crittenden MD, Babikian VL. Ultrasound Med Biol. 2009 Aug;35(8):1235-41. Epub 2009 Jun 21.

Cerebral ischemic events associated with ‘bubble study’ for identification of right to left shunts. Romero JR, Frey JL, Schwamm LH, Demaerschalk BM, Chaliki HP, Parikh G, Burke RF, Babikian VL. Stroke. 2009 Jul;40(7):2343-8. Epub 2009 Jun 4.

Intraoperative cerebral high-intensity transient signals and postoperative cognitive function: a systematic review. Martin KK, Wigginton JB, Babikian VL, Pochay VE, Crittenden MD, Rudolph JL. Am J Surg. 2009 Jan;197(1):55-63. Epub 2008 Aug 23. Review.

Rudolph J, Chaglassian A, Pochay V, Wigginton J, Sorond F, Crittenden M, Babikian V.L. Severe extracranial internal carotid artery stenosis impacts cerebral hemodynamics during coronary artery bypass graft surgery. Neurology. 68:(S1): A131, 2007.

Wigginton J, Rudolph J, Babikian V, Khuri S, Pochay V, Marcantonio E.. Microemboli during cardiac surgery are not associated with postoperative delirium. J Am Geriatr Soc. 55:(4S): S218, 2007.

Rudolph J, Tilahun D, Treanor R, Pochay V, Mahendrakar M, Sagar P, Babikian V.. Use of large bore syringe creates significantly fewer high intensity transient signals into cardiopulmonary bypass sytem than a small bore syringe. Perfusion. 21: 67-71, 2006.

Romero JR, Babikian VL, Katz DI, Finkelstein SP. Neuroprotection and stroke rehabilitation: Modulation and enhancement of recovery. Behavioral Neurology. 17: 17-24, 2006.

Simons JS, Peers PV, Hwang DY, Ally BA, Fletcher PC, Budson AE. Is the parietal lobe necessary for recollection in humans? Neuropsychologia, 2008; 46:1185-1191.

Ally BA, Waring JD, Beth EH, McKeever JD, Milberg WP, Budson AE. Aging memory for pictures: Using high-density event-related potentials to understand the effects of aging on the picture superiority effect. Neuropsychologia, 2008; 46(2): 679-689.

Waring JD, Chong H, Wolk DA, Budson AE. Preserved metamemorial ability in patients with mild Alzheimer’s disease: Shifting response bias. Brain and Cognition, 2008; 66(1): 32-39.

Wolk DA, Schacter DL, Lygizos M, Mandu-Sen N, Chong H, Holcomb PJ, Daffner KR, Budson AE. ERP correlates of Remember/Know decisions: Association with the late posterior negativity. Biological Psychology 2007 75 131-135.

Ally BA, Budson AE. The worth of pictures: Using high density event-related potentials to understand the memorial power of pictures and the dynamics of recognition memory. NeuroImage 2007 35 378-395.

Ally BA, Jones GE, Cole JA, Budson AE. Sensory gating in patients with Alzheimer’s disease and their biological children. American Journal of Alzheimer’s Disease and Other Dementias 2007 21 439-447.

Gallo DA, Shahid KR, Olson MA, Solomon TM, Schacter DL, Budson AE. Overdependence on degraded gist memory in Alzheimer’s disease. Neuropsychology 2006 20 625-632.

Wolk DA, Schacter DL, Lygizos M, Mandu-Sen N, Holcomb PJ, Daffner KR, Budson AE. ERP correlates of recognition memory: Effects of retention interval and false alarms. Brain Research 2006 1096 148-162.

Budson AE, Wolk DA, Chong H, Waring JD. Episodic memory in Alzheimer’s disease: Separating response bias from discrimination. Neuropsychologia 2006 44 2222-2232.

Budson AE, Todman RW, Chong H, Adams EH, Kensinger EA, Krangel TS, Wright CI. False recognition of emotional word lists in younger adults, older adults, and patients with Alzheimer’s disease. Cognitive and Behavioral Neurology 2006 19 71-78.

Budson AE, Mather M, Chong H. Memory for Choices in Alzheimer’s Disease. Dementia and Geriatric Cognitive Disorders 2006 22 150-158.

Mitchell JP, Sullivan AL, Schacter DL, Budson AE. Misattribution errors in Alzheimer’s disease: The illusory truth effect. Neuropsychology 2006 20 185-192.

Ally BA, Jones GE, Cole JA, Budson AE. The P300 component in patients with Alzheimer’s disease and their biological children. Biological Psychology 2006 72 180-187.

Budson AE, Todman RW, Schacter DL. Gist memory in Alzheimer’s disease: Evidence from categorized pictures. Neuropsychology 2006 20 113-122.

Kim SY, Schrock L, Wilson R, Frank S, Holloway RG, Kieburtz K, De Vries RG. An Approach to Evaluating Therapeutic Misconception. IRB: Ethics & Human Research 2009 31(5): 7-14.

Huntington Study Group/Tetra-HD Investigators (Frank S corresponding author). Tetrabenazine as anti-chorea therapy in Huntington Disease: an open-label continuation study. BMC Neurology 2009, 9:62 (18 December 2009).

Frank S, Wilson R, Holloway R, Zimmerman C, Peterson D, Kieburtz K, Kim SYH. Ethics of sham surgery: Perspective of Patients. Movement Disorders January 2008;23(1): 63-68.

Frank S, Ondo W, Hunter C, Marshall F, Walker F, Eberly S, Factor S, Fahn S, Hunt V, Oakes D, Plumb S, Shinaman A, Shoulson I, Zhao H, Jankovic J. A Randomized, Double-Blind, Placebo-Controlled, Staggered Withdrawal Study in Patients with Huntington’s Disease Treated with Tetrabenazine. Clinical Neuropharmacology 2008 31 (3):127-133.

Kim SY, Holloway RG, Frank S, Wilson R, Kieburtz K. Trust in early phase research: therapeutic optimism and protective pessimism. Med Health Care Philos 2008 (11):393-401. 2008 Jul 16 [Epub ahead of print].

Huntington Study Group/TREND-HD Investigators (Frank S, site investigator). Randomized controlled trial of ethyl-eicosapentaenoic acid in Huntington disease: the TREND-HD study Arch Neurol. 2008 Dec;65(12):1582-9.

Dorsey ER, Beck CA, Adams M, Chadwick G, de Blieck EA, McCallum C, Briner L, Deuel L, Clarke A, Stewart R, Shoulson I; Huntington Study Group/TREND-HD Investigators (Frank S, site investigator). Communicating clinical trial results to research participants Arch Neurol. 2008 Dec;65(12):1590-5.

Frank S. Training Matters: Teaching Residents to be Teachers. Nature Clinical Practice Neurology 3(4); April 2007:235.

Huntington Study Group (Frank S, third author and medical monitor). Tetrabenazine as Anti-Chorea Therapy in Huntington’s Disease: A Randomized Control Trial. Neurology 66 (3);Feb 14, 2006:366-372.

Kim S, Holloway R, Frank S, Beck C, Zimmerman C, Wilson R, Kieburtz K. Volunteering for early phase gene transfer research in Parkinson’s disease. Neurology 2006 Apr 11;66(7):1010-5. Epub 2006 Mar 15.

The role of the neurologist in cases of abuse and neglect. Hohler AD, Rush SR. Neurologist. 2007 Mar;13(2):73-8. Review.

Effectiveness of an inpatient multidisciplinary rehabilitation program for people with Parkinson disease. Ellis T, Katz DI, White DK, DePiero TJ, Hohler AD, Saint-Hilaire M. Phys Ther. 2008 Jul;88(7):812-9. Epub 2008 Apr 24.

Differences in Motor and Cognitive Function in Patients with Parkinson’s Disease with and without Orthostatic Hypotension. Hohler AD, Zuzuárregui JR, Katz DI, Depiero TJ, Hehl CL, Leonard A, Allen V, Dentino J, Gardner M, Phenix H, Saint-Hilaire M, Ellis T. Int J Neurosci. 2011 Nov 24.

Effectiveness of an inpatient movement disorders program for patients with atypical parkinsonism. Hohler AD, Tsao JM, Katz DI, Dipiero TJ, Hehl CL, Leonard A, Allen V, Gardner M, Phenix H, Saint-Hilaire M, Ellis T. Parkinsons Dis. 2012;2012:871974. Epub 2011 Nov 10.

Differences in motor and cognitive function in patients with Parkinson’s disease with and without orthostatic hypotension. Hohler AD, Zuzuárregui JR, Katz DI, Depiero TJ, Hehl CL, Leonard A, Allen V, Dentino J, Gardner M, Phenix H, Saint-Hilaire M, Ellis T. Int J Neurosci. 2012 May;122(5):233-6. Epub 2011 Dec 22.

Probable hereditary multiple system atrophy-autonomic (MSA-A) in a family in the United States. Hohler AD, Singh VJ. J Clin Neurosci. 2012 Mar;19(3):479-80. Epub 2012 Jan 16.

The American Academy of Neurology position statement on abuse and violence. Schulman EA, Hohler AD. Neurology. 2012 Feb 7;78(6):433-5. Epub 2012 Jan 25.

Diagnostic utility of the NAB List Learning test in Alzheimer’s disease and amnestic mild cognitive impairment. Gavett BE, Poon SJ, Ozonoff A, Jefferson AL, Nair AK, Green RC, Stern RA. J Int Neuropsychol Soc. 2009 Jan;15(1):121-9.

Sustained attention is associated with left ventricular ejection fraction in older adults with heart disease. Jerskey BA, Cohen RA, Jefferson AL, Hoth KF, Haley AP, Gunstad JJ, Forman DE, Sweet LH, Poppas A. J Int Neuropsychol Soc. 2009 Jan;15(1):137-41.

Atlas-derived perfusion correlates of white matter hyperintensities in patients with reduced cardiac output. Jefferson AL, Holland CM, Tate DF, Csapo I, Poppas A, Cohen RA, Guttmann CR. Neurobiol Aging. 2011 Jan;32(1):133-9. Epub 2009 Mar 9.

Leukoaraiosis severity and list-learning in dementia. Price CC, Garrett KD, Jefferson AL, Cosentino S, Tanner JJ, Penney DL, Swenson R, Giovannetti T, Bettcher BM, Libon DJ. Clin Neuropsychol. 2009 Aug;23(6):944-61.

Longitudinal cognitive performance in older adults with cardiovascular disease: evidence for improvement in heart failure. Stanek KM, Gunstad J, Paul RH, Poppas A, Jefferson AL, Sweet LH, Hoth KF, Haley AP, Forman DE, Cohen RA. J Cardiovasc Nurs. 2009 May-Jun;24(3):192-7.

Regional White Matter Signal Abnormalities and Cognitive Correlates Among Geriatric Patients with Treated Cardiovascular Disease. Tate DF, Jefferson AL, Brickman AM, Hoth KF, Gunstad J, Bramley K, Paul RH, Poppas A, Cohen RA. Brain Imaging Behav. 2008 Sep 1;2(3):200-206.

Subjective cognitive complaints relate to white matter hyperintensities and future cognitive decline in patients with cardiovascular disease. Haley AP, Hoth KF, Gunstad J, Paul RH, Jefferson AL, Tate DF, Ono M, Jerskey BA, Poppas A, Sweet LH, Cohen RA. Am J Geriatr Psychiatry. 2009 Nov;17(11):976-85.

Predicting cognitive decline and conversion to Alzheimer’s disease in older adults using the NAB List Learning test. Gavett BE, Ozonoff A, Doktor V, Palmisano J, Nair AK, Green RC, Jefferson AL, Stern RA. J Int Neuropsychol Soc. 2010 Jul;16(4):651-60. Epub 2010 Apr 7.

Cardiac output as a potential risk factor for abnormal brain aging. Jefferson AL. J Alzheimers Dis. 2010;20(3):813-21. Review.

Perceptions, knowledge, incentives, and barriers of brain donation among African American elders enrolled in an Alzheimer’s research program. Lambe S, Cantwell N, Islam F, Horvath K, Jefferson AL. Gerontologist. 2011 Feb;51(1):28-38. Epub 2010 Aug 2.

Cardiac index is associated with brain aging: the Framingham Heart Study. Jefferson AL, Himali JJ, Beiser AS, Au R, Massaro JM, Seshadri S, Gona P, Salton CJ, DeCarli C, O’Donnell CJ, Benjamin EJ, Wolf PA, Manning WJ. Circulation. 2010 Aug 17;122(7):690-7. Epub 2010 Aug 2.

Factors associated with African American and White elders’ participation in a brain donation program. Jefferson AL, Lambe S, Cook E, Pimontel M, Palmisano J, Chaisson C. Alzheimer Dis Assoc Disord. 2011 Jan-Mar;25(1):11-6.

Clinical research participation among aging adults enrolled in an Alzheimer’s Disease Center research registry. Jefferson AL, Lambe S, Chaisson C, Palmisano J, Horvath KJ, Karlawish J. J Alzheimers Dis. 2011;23(3):443-52.

Bone mineral content and density in Rett syndrome and their contributing factors. Jefferson AL, Woodhead HJ, Fyfe S, Briody J, Bebbington A, Strauss BJ, Jacoby P, Leonard H. Pediatr Res. 2011 Apr;69(4):293-8.

Conceptual and Measurement Challenges in Research on Cognitive Reserve. Jones RN, Manly J, Glymour MM, Rentz DM, Jefferson AL, Stern Y. J Int Neuropsychol Soc. 2011 Mar 17:1-9.

Inflammatory markers and neuropsychological functioning: the Framingham Heart Study. Jefferson AL, Massaro JM, Beiser AS, Seshadri S, Larson MG, Wolf PA, Au R, Benjamin EJ. Neuroepidemiology. 2011;37(1):21-30. Epub 2011 Jul 13.

A life course model of cognitive activities, socioeconomic status, education, reading ability, and cognition. Jefferson AL, Gibbons LE, Rentz DM, Carvalho JO, Manly J, Bennett DA, Jones RN. J Am Geriatr Soc. 2011 Aug;59(8):1403-11. doi: 10.1111/j.1532-5415.2011.03499.x. Epub 2011 Jul 28.

Relation of left ventricular ejection fraction to cognitive aging (from the Framingham Heart Study). Jefferson AL, Himali JJ, Au R, Seshadri S, Decarli C, O’Donnell CJ, Wolf PA, Manning WJ, Beiser AS, Benjamin EJ. Am J Cardiol. 2011 Nov 1;108(9):1346-51. Epub 2011 Aug 30.

Prediction of memory rehabilitation outcomes in traumatic brain injury by using functional magnetic resonance imaging. Strangman GE, O’Neil-Pirozzi TM, Goldstein R, Kelkar K, Katz DI, Burke D, Rauch SL, Savage CR, Glenn MB. Arch Phys Med Rehabil. 2008 May;89(5):974-81.

Neurophysiological alterations during strategy-based verbal learning in traumatic brain injury. Strangman GE, Goldstein R, O’Neil-Pirozzi TM, Kelkar K, Supelana C, Burke D, Katz DI, Rauch SL, Savage CR, Glenn MB. Neurorehabil Neural Repair. 2009 Mar-Apr;23(3):226-36. Epub 2008 Dec 1.

Long-term effects of rivastigmine capsules in patients with traumatic brain injury. Silver JM, Koumaras B, Meng X, Potkin SG, Reyes PF, Harvey PD, Katz DI, Gunay I, Arciniegas DB. Brain Inj. 2009 Feb;23(2):123-32.

Predictors of short-term outcome in brain-injured patients with disorders of consciousness. Whyte J, Gosseries O, Chervoneva I, DiPasquale MC, Giacino J, Kalmar K, Katz DI, Novak P, Long D, Childs N, Mercer W, Maurer P, Eifert B. Prog Brain Res. 2009;177:63-72.

Natural history of recovery from brain injury after prolonged disorders of consciousness: outcome of patients admitted to inpatient rehabilitation with 1-4 year follow-up. Katz DI, Polyak M, Coughlan D, Nichols M, Roche A. Prog Brain Res. 2009;177:73-88.

A controlled treatment study of internal memory strategies (I-MEMS) following traumatic brain injury. O’Neil-Pirozzi TM, Strangman GE, Goldstein R, Katz DI, Savage CR, Kelkar K, Supelana C, Burke D, Rauch SL, Glenn MB. J Head Trauma Rehabil. 2010 Jan-Feb;25(1):43-51.

Test-re-test reliability of the virtual planning test in individuals with traumatic brain injury. O’Neil-Pirozzi TM, Goldstein R, Strangman GE, Katz DI, Glenn MB. Brain Inj. 2010;24(3):509-16.

Regional brain morphometry predicts memory rehabilitation outcome after traumatic brain injury. Strangman GE, O’Neil-Pirozzi TM, Supelana C, Goldstein R, Katz DI, Glenn MB. Front Hum Neurosci. 2010 Oct 14;4:182.

Assessment scales for disorders of consciousness: evidence-based recommendations for clinical practice and research. American Congress of Rehabilitation Medicine, Brain Injury-Interdisciplinary Special Interest Group, Disorders of Consciousness Task Force, Seel RT, Sherer M, Whyte J, Katz DI, Giacino JT, Rosenbaum AM, Hammond FM, Kalmar K, Pape TL, Zafonte R, Biester RC, Kaelin D, Kean J, Zasler N. Arch Phys Med Rehabil. 2010 Dec;91(12):1795-813. Review.

Dissociations between behavioural and functional magnetic resonance imaging-based evaluations of cognitive function after brain injury. Bardin JC, Fins JJ, Katz DI, Hersh J, Heier LA, Tabelow K, Dyke JP, Ballon DJ, Schiff ND, Voss HU. Brain. 2011 Mar;134(Pt 3):769-82.

Placebo-controlled trial of amantadine for severe traumatic brain injury. Giacino JT, Whyte J, Bagiella E, Kalmar K, Childs N, Khademi A, Eifert B, Long D, Katz DI, Cho S, Yablon SA, Luther M, Hammond FM, Nordenbo A, Novak P, Mercer W, Maurer-Karattup P, Sherer M. N Engl J Med. 2012 Mar 1;366(9):819-26.

Motor neuronal protection by L-arginine prolongs survival of mutant SOD1 (G93A) ALS mice. Lee J, Ryu H, Kowall NW. Biochem Biophys Res Commun. 2009 Jul 0;384(4):524-9. Epub 2009 May 8.

Differential regulation of neuronal and inducible nitric oxide synthase (NOS) in the spinal cord of mutant SOD1 (G93A) ALS mice. Lee J, Ryu H, Kowall NW. Biochem Biophys Res Commun. 2009 Sep 11;387(1):202-6. Epub 2009 Jul 4.

Anti-inflammatory treatment in AD mice protects against neuronal pathology. Choi JK, Jenkins BG, Carreras I, Kaymakcalan S, Cormier K, Kowall NW, Dedeoglu A. Exp Neurol. 2010 Jun;223(2):377-84. Epub 2009 Aug 10.

Moderate exercise delays the motor performance decline in a transgenic model of ALS. Carreras I, Yuruker S, Aytan N, Hossain L, Choi JK, Jenkins BG, Kowall NW, Dedeoglu A. Brain Res. 2010 Feb 8;1313:192-201. Epub 2009 Dec 5.

TDP-43 proteinopathy and motor neuron disease in chronic traumatic encephalopathy. McKee AC, Gavett BE, Stern RA, Nowinski CJ, Cantu RC, Kowall NW, Perl DP, Hedley-Whyte ET, Price B, Sullivan C, Morin P, Lee HS, Kubilus CA, Daneshvar DH, Wulff M, Budson AE. J Neuropathol Exp Neurol. 2010 Sep;69(9):918-29.

Modulation of lipid peroxidation and mitochondrial function improves neuropathology in Huntington’s disease mice. Lee J, Kosaras B, Del Signore SJ, Cormier K, McKee A, Ratan RR, Kowall NW, Ryu H. Acta Neuropathol. 2011 Apr;121(4):487-98. Epub 2010 Dec 16.

Differential expression of c-Ret in motor neurons versus non-neuronal cells is linked to the pathogenesis of ALS. Ryu H, Jeon GS, Cashman NR, Kowall NW, Lee J. Lab Invest. 2011 Mar;91(3):342-52. Epub 2011 Jan 31.

Memantine for posttraumatic stress disorder in an older veteran. Chopra MP, Trevino KM, Kowall NW. J Clin Psychopharmacol. 2011 Dec;31(6):787-8.

ATRX induction by mutant huntingtin via Cdx2 modulates heterochromatin condensation and pathology in Huntington’s disease. Lee J, Hong YK, Jeon GS, Hwang YJ, Kim KY, Seong KH, Jung MK, Picketts DJ, Kowall NW, Cho KS, Ryu H. Cell Death Differ. 2012 Jan 13. doi: 10.1038/cdd.2011.196.

McGeeney BE, Barest G, Grillone G. Thunderclap headache from complicated sinusitis. Headache 2006;46:517-520.

McGeeney BE. Headache and Anosmia. Headache 2006;46:1199.

McGeeney BE. Valsalva-Induced Cluster Headache. J Headache Pain 2006 7: 416-418

Loder E, Rizzoli P, McGeeney, B et al. Cluster headache treatment dilemmas: the experts respond. Curr Pain Headache Rep. 2007 Apr;11(2):141-7.

Adjuvant agents in cancer pain. McGeeney BE. Clin J Pain. 2008 May;24 Suppl 10:S14-20. Review.

Postural headache. Lavigne C, McGeeney BE. Headache. 2009 Jun;49(6):938-40.

Pharmacological management of neuropathic pain in older adults: an update on peripherally and centrally acting agents. McGeeney BE. J Pain Symptom Manage. 2009 Aug;38(2 Suppl):S15-27. Review.

Correlation of Alzheimer Disease Neuropathologic Changes With Cognitive Status: A Review of the Literature. Nelson PT, Alafuzoff I, Bigio EH, Bouras C, Braak H, Cairns NJ, Castellani RJ, Crain BJ, Davies P, Tredici KD, Duyckaerts C, Frosch MP, Haroutunian V, Hof PR, Hulette CM, Hyman BT, Iwatsubo T, Jellinger KA, Jicha GA, Kövari E, Kukull WA, Leverenz JB, Love S, Mackenzie IR, Mann DM, Masliah E, McKee AC, Montine TJ, Morris JC, Schneider JA, Sonnen JA, Thal DR, Trojanowski JQ, Troncoso JC, Wisniewski T, Woltjer RL, Beach TG. J Neuropathol Exp Neurol. 2012 Apr 13.

The Framingham Brain Donation Program: Neuropathology Along The Cognitive Continuum. Au R, Seshadri S, Knox K, Beiser A, Himali JJ, Cabral HJ, Auerbach S, Green RC, Wolf PA, McKee AC. Curr Alzheimer Res. 2012 Apr 2.

Long-term consequences of repetitive brain trauma: chronic traumatic encephalopathy. Stern RA, Riley DO, Daneshvar DH, Nowinski CJ, Cantu RC, McKee AC. PM R. 2011 Oct;3(10 Suppl 2):S460-7. Review.

Exosome-associated tau is secreted in tauopathy models and is selectively phosphorylated in cerebrospinal fluid in early Alzheimer disease. Saman S, Kim W, Raya M, Visnick Y, Miro S, Saman S, Jackson B, McKee AC, Alvarez VE, Lee NC, Hall GF. J Biol Chem. 2012 Feb 3;287(6):3842-9. Epub 2011 Nov 4.

Long-term consequences: effects on normal development profile after concussion. Daneshvar DH, Riley DO, Nowinski CJ, McKee AC, Stern RA, Cantu RC. Phys Med Rehabil Clin N Am. 2011 Nov;22(4):683-700, ix. Epub 2011 Sep 23. Review.

Clinical appraisal of chronic traumatic encephalopathy: current perspectives and future directions. Gavett BE, Cantu RC, Shenton M, Lin AP, Nowinski CJ, McKee AC, Stern RA. Curr Opin Neurol. 2011 Dec;24(6):525-31. Review.

Pyroglutamate-Aβ 3 and 11 colocalize in amyloid plaques in Alzheimer’s disease cerebral cortex with pyroglutamate-Aβ 11 forming the central core. Sullivan CP, Berg EA, Elliott-Bryant R, Fishman JB, McKee AC, Morin PJ, Shia MA, Fine RE. Neurosci Lett. 2011 Nov 14;505(2):109-12. Epub 2011 Oct 6.

Chronic traumatic encephalopathy: a potential late effect of sport-related concussive and subconcussive head trauma. Gavett BE, Stern RA, McKee AC. Clin Sports Med. 2011 Jan;30(1):179-88, xi. Review.

Helmets and mouth guards: the role of personal equipment in preventing sport-related concussions. Daneshvar DH, Baugh CM, Nowinski CJ, McKee AC, Stern RA, Cantu RC. Clin Sports Med. 2011 Jan;30(1):145-63, x. Review.

The epidemiology of sport-related concussion. Daneshvar DH, Nowinski CJ, McKee AC, Cantu RC. Clin Sports Med. 2011 Jan;30(1):1-17, vii. Review.

TDP-43 proteinopathy and motor neuron disease in chronic traumatic encephalopathy. McKee AC, Gavett BE, Stern RA, Nowinski CJ, Cantu RC, Kowall NW, Perl DP, Hedley-Whyte ET, Price B, Sullivan C, Morin P, Lee HS, Kubilus CA, Daneshvar DH, Wulff M, Budson AE. J Neuropathol Exp Neurol. 2010 Sep;69(9):918-29.

Shulman, L, Montouris, GD, Clinical Perspective in Women with Epilepsy, Clinical Guidelines, Supplement to The Female Patient, April, 2007, p. 5-12.

Montouris, GD, Jagoda, A, ”Management of Breakthrough Seizures in the Emergency Department: Continuity of Care, Current Medical Research and Opinion, Vol 23, No 7, 1583-1592.

Montouris, GD, “Seizures and Reproductive Health of Women”Primary Neuro News, Spring 2007, Vol 1, issue 2, pp 1-6.

Conversions between monotherapies in epilepsy: expert consensus. St Louis EK, Gidal BE, Henry TR, Kaydanova Y, Krumholz A, McCabe PH, Montouris GD, Rosenfeld WE, Smith BJ, Stern JM, Waterhouse EJ, Schulz RM, Garnett WR, Bramley T. Epilepsy Behav. 2007 Sep;11(2):222-34. Epub 2007 Jun 22.

Report of the American Epilepsy Society and the Epilepsy Foundation joint task force on sudden unexplained death in epilepsy. So EL, Bainbridge J, Buchhalter JR, Donalty J, Donner EJ, Finucane A, Graves NM, Hirsch LJ, Montouris GD, Temkin NR, Wiebe S, Sierzant TL. Epilepsia. 2009 Apr;50(4):917-22. Epub 2008 Nov 24.

A quick and reliable EEG montage for the detection of seizures in the critical care setting. Karakis I, Montouris GD, Otis JA, Douglass LM, Jonas R, Velez-Ruiz N, Wilford K, Espinosa PS. J Clin Neurophysiol. 2010 Apr;27(2):100-5.

Rational approach to treatment options for Lennox-Gastaut syndrome. Montouris GD. Epilepsia. 2011 Aug;52 Suppl 5:10-20. doi: 10.1111/j.1528-1167.2011.03178.x.

Karamohamed S, Golbe LI, Mark MH, Lazzarini AM, Suchowersky O, Labelle N, Guttman M, Currie LJ, Wooten GF, Stacy M, Saint-Hilaire M, Feldman RG, Liu J, Shoemaker CM, Wilk JB, DeStefano AL, Latourelle JC, Xu G, Watts R, Growdon J, Lew M, Waters C, Vieregge P, Pramstaller PP, Klein C, Racette BA, Perlmutter JS, Parsian A, Singer C, Montgomery E, Baker K, Gusella JF, Herbert A, Myers RH. Absence of previously reported variants in the SCNA (G88C and G209A), NR4A2 (T291D and T245G) and the DJ-1 (T497C) genes in familial Parkinson’s disease from the GenePD study. Movement Disorders 2005; 20:1188-1191.

Karamohamed S, Latourelle JC, Racette BA, Perlmutter JS, Wooten GF, Lew MF, Klein C, Shill H, Golbe LI, Mark MH, Guttman M, Nicholson G, Wilk JB, Saint-Hilaire MH, DeStefano AL, Prakash R, Williamson S, Tobin J, Suchowersky O, Labelle N, Growdon JH, Singer C, Watts RL, Goldwurm S, Pezzoli G, Baker KB, Giroux ML, Pramstaller PP, Burn DJ, Chinnery PF, Sherman S, Vieregge P, Litvan I, Gusella JF, Myers RH, Parsian A. BDNF genetic variants are associated with onset-age of familial Parkinson’s disease: GenePD study. Neurology 2005; 65:1823-1825.

Seong IS, Ivanova E, Lee JM, Choo YS, Fossale E, Anderson M, Gusella JF, Laramie JM, Myers RH, Lesort M, Macdonald ME. The HD CAG Repeat Implicates a Dominant Property of Huntingtin in Mitochondrial Energy Metabolism. Human Molecular Genetics. 2005; 14:2871-2880.

Wilk JB, Myers RH, Pankow JS, Hunt SC, Leppert MF, Freedman BI, Province MA, Ellison RC. Adrenergic receptor polymorphisms associated with resting heart rate: The HyperGEN Study. Annals of Human Genetics 2006; 70:566-573.

Sun M, Latourelle JC, Wooten GF, Lew MF, Klein C, Shill HA, Golbe LI, Mark MH, Racette BA, Perlmutter JS, Parsian A, Guttman M, Nicholson G, Xu G, Wilk JB, Saint-Hilaire MH, DeStefano AL, Prakash R, Williamson S, Suchowersky O, Labelle N, Growdon JH, Singer C, Watts RL, Goldwurm S, Pezzoli G, Baker KB, Pramstaller PP, Burn DJ, Chinnery PF, Sherman S, Vieregge P, Litvan I, Gillis T, MacDonald ME, Myers RH, Gusella JF. Heterozygosity for Parkin Mutation Influences Onset Age in Familial Parkinson’s Disease: The GenePD Study. Archives of Neurology 2006;63:826-832.

Laramie JM, Wilk JB, Hunt SC, Ellison RC, Chakravarti A, Boerwinkle E, Myers RH. Evidence for a Gene Influencing Heart Rate on Chromosome 5p13-14 in a Meta-Analysis of Genome-Wide Scans from the NHLBI Family Blood Pressure Program. BMC Medical Genetics 2006; 7:17.

Myers RH. Considerations for Genomewide Association Studies in Parkinson Disease. (editorial). American Journal of Human Genetics 2006; 78:1081.

Lloret A, Dragileva E, Teed A, Espinola J, Fossale E, Gillis T, Lopez E, Myers RH, MacDonald ME, Wheeler VC. Genetic background modifies nuclear mutant huntingtin accumulation and HD CAG repeat instability in Huntington’s disease knock-in mice. Human Molecular Genetics 2006; 15:2015-2024.

Kishikawa S, Li J-L, Gillis T, Hakky MH, Warby S, Hayden M, MacDonald ME, Myers RH, Gusella JF. Brain-derived neurotrophic factor does not influence age at neurologic onset of Huntington’s disease. Neurobiology of Disease 2006; 24:280-285.

Li J-L, Hayden MR, Warby SC, Durr A, Morrison PJ, Nance M, Ross CA, Margolis RL, Rosenblatt A, Squitieri F, Frati L, Gomez-Tortosa E, Ayuso Garcia C, Suchowersky O, Klimek ML, Trent RA, McCusker E, Novelletto A, Frontali M, Paulsen JS, Jones R, Ashizawa T, Lazzarini A, Wheeler VC, Prakash R, Xu G, Djousse L, Mysore JS, Gillis T, Hakky M, Cupples LA, Saint-Hilaire MH, Cha J-HJ, Hersch SM, Penney JB, Harrison MB, Perlman SL, Zanko A, Abramson RK, Lechich AJ, Duckett A, Marder K, Conneally PM, Gusella JF, MacDonald ME, Myers RH. Genome-wide Significance for a Modifier of Age at Neurological Onset in Huntington Disease at 6q23-24: the HD MAPS Study. BMC Medical Genetics 2006, 7:71

Zeng W, Gillis T, Hakky M, Djousse L, Myers RH, MacDonald ME, Gusella JF. Genetic analysis of the GRIK2 modifier effect in Huntington’s disease. BMC Neuroscience 2006, 7:62.

Wilk JB, Tobin JE, Suchowersky O, Shill H, Klein C, Wooten GF, Lew M, Mark MH, Guttman M, Watts RL, Singer C, Growdon J, Latourelle JC, Saint-Hilaire M, DeStefano AL, Prakash R, Williamson S, Berg CJ, Sun M, Goldwurm S, Pezzoli G, Racette BA, Perlmutter JS, Parsian A, Baker K, Giroux ML, Litvan I, Pramstaller PP, Nicholson GA, Burn DJ, Chinnery PF, Vieregge P, Slevin JT, Cambi F, MacDonald ME, Gusella JF, Myers RH, Golbe LI. Herbicide exposure modifies GSTP1 haplotype association to Parkinson onset age: The GenePD Study. Neurology 2006; 67:2206-2210.

Feitosa MF, Province MA, Heiss G, Arnett DK, Myers RH, Pankow JS, Hopkins PN, Borecki IB. Evidence of QTL on 15q21 for High-Density Lipoprotein Cholesterol: The National Heart, Lung, and Blood Institute Family Heart Study. Atherosclerosis 2007;190:232-237

Tobin JE, Cui J, Wilk JB, Latourelle JC, Laramie JM, McKee AC, Guttman M, Karamohamed S, DeStefano AL, Myers, RH. Sepiapterin reductase expression is increased in Parkinson’s disease brain tissue. Brain Research 2007; 1139:42-47.

A quick and reliable EEG montage for the detection of seizures in the critical care setting. Karakis I, Montouris GD, Otis JA, Douglass LM, Jonas R, Velez-Ruiz N, Wilford K, Espinosa PS. J Clin Neurophysiol. 2010 Apr;27(2):100-5.

Suspecting optic neuritis, diagnosing Bartonella cat scratch disease. Gan JJ, Mandell AM, Otis JA, Holmuhamedova M, Perloff MD. Arch Neurol. 2011 Jan;68(1):122-6.

Anorgasmia with gabapentin may be common in older patients. Perloff MD, Thaler DE, Otis JA. Am J Geriatr Pharmacother. 2011 Jun;9(3):199-203. Epub 2011 May 23.

Induction of P-glycoprotein expression and activity by ritonavir in bovine brain microvessel endothelial cells. Perloff MD, von Moltke LL, Fahey JM, Greenblatt DJ. J Pharm Pharmacol. 2007 Jul;59(7):947-53.

Iatrogenic hyperammonemia after anorexia. Welsh E, Kucera J, Perloff MD. Arch Intern Med. 2010 Mar 8;170(5):486-8.

Teaching video neuroimages: the elusive L5 reflex. Perloff MD, Leroy AM, Ensrud ER. Neurology. 2010 Sep 14;75(11):e50. No abstract available.

Interlaminar versus transforaminal epidural steroids for the treatment of subacute lumbar radicular pain: a randomized, blinded, prospective outcome study. Gharibo CG, Varlotta GP, Rhame EE, Liu EC, Bendo JA, Perloff MD. Pain Physician. 2011 Nov-Dec;14(6):499-511.

Writing from the wards: advice for residents. Perloff MD, Zuzuárregui JR, Frank SA. Neurologist. 2012 Mar;18(2):96-8.

Gabapentin use in the prevention of succinylcholine-induced fasciculation and myalgia. Rayhill ML, Perloff MD. J Postgrad Med. 2012 Jan-Mar;58(1):1-2.

Pikula A, Beiser AS, Himali JJ, Debette S, DeCarli C, Au R, Selhub J, Tofler GH, Wang TJ, Kelly-Hayes M, Kase CS, Benjamin EJ, Vasan RS, Wolf PA, Seshadri S. Multiple Biomarkers and Risk of Clinical and Subclinical Vascular Brain Injury: The Framingham Offspring Study. Circulation 2011

Pikula A, Stefanidou M, Romero JR, Kase CS. Pure Motor Upper Limb Weakness and Infarction in the Precentral Gyrus: The Mechanism of Stroke. JVIN 2010

Seshadri S, Beiser A, Pikula A, Himali JJ, Kelly-Hayes M, Debette S, DeStefano AL, Romero JR, Kase CS, Wolf PA. Parental occurrence of stroke and risk of stroke in their children: the Framingham study. Circulation. 2010 Mar 23;121(11):1304-12. Epub 2010 Mar 8.

Debette S, Wolf PA, Beiser A, Au R, Himali JJ, Pikula A, Auerbach S, Decarli C, Seshadri S. Association of parental dementia with cognitive and brain MRI measures in middle-aged adults. Neurology. 2009 Dec 15;73(24):2071-8. Epub 2009 Dec 9.

Pikula A, Böger RH, Beiser AS, Maas R, DeCarli C, Schwedhelm E, Himali JJ, Schulze F, Au R, Kelly-Hayes M, Kase CS, Vasan RS, Wolf PA, Seshadri S. Association of plasma ADMA levels with MRI markers of vascular brain injury: Framingham offspring study. Stroke. 2009 Sep;40(9):2959-64. Epub 2009 Jul 30.

Pikula A, Almodovar JL, Nguyen TN. Teaching NeuroImages: cerebral arteriovenous malformation in hereditary hemorrhagic telangiectasia. Neurology 2009 Mar 10;72(10):e45.

Saint-Hilaire M, Ellis T. A Prescription for Physical Therapy and Exercise. Advances in Parkinson Disease 2013, 2:118-120 doi:10.4236/apd.2013.24023

Ellis T, Latham NK, De Angelis TR, Thomas CA, Saint-Hilaire M, Bickmore T. Feasibility of a Virtual Exercise Coach to Promote Walking in Community-Dwelling Persons with Parkinson Disease. American Journal of Physical Medicine & Rehabilitation. June 2013-Vol 92:6. pp472-485

Ramos EM, Latourelle JC, Gillis T, Mysore JS, Squitieri F, Di Pardo A, Di Donato S, Gellera C, Hayden MR, Morrison PJ, Nance M, Ross CA, Margolis RL, Gomez-Tortosa E, Ayuso C, Suchowersky O, Trent RJ, Mc Cusker E, Novelletto A, Frontali M, Jones R, Ashizawa T, Frank S, Saint-Hilaire MH, Hersch SM, Rosas HD, Lucente D, Harrison MB, Zanko A, Abramson RK, Marder K, Gusella JF, Lee JM, Alonso I, Sequeiros J, Myers RH, Macdonald ME. Candidate Glutamatergic and Dopaminergic Pathway Gene Variants do not influence Huntington’s Disease Motor Onset. Neurogenetics 2013, 14:173-179 doi: 10.1007/s10048-013-0364-y

Roy S, Cole B, Gilmore D, De Luca C, Thomas C, Saint-Hilaire M, Syed N. High Resolution Tracking of Motor Disorders In Parkinson’s Disease during Unconstrained Activity. Mov.Disord 2013,28:1080-1087.doi:10.1002/mds.25391

Zhang R, Spengler DC, Saint-Hilaire MH, Hohler AD.Association of adverse effects with Monoamine Oxidase type B Inhibitor and Catechol-O- Methyl Transferase Inhibitor Combination Therapy In Parkinson’s Disease Patients. Advances in Parkinson’s Disease. 1:5-10,2012

Common SNP-based haplotype analysis of the 4p16.3 Huntington disease gene region. Lee JM, Gillis T, Mysore JS, Ramos EM, Myers RH, Hayden MR, Morrison PJ, Nance M, Ross CA, Margolis RL, Squitieri F, Griguoli A, Di Donato S, Gomez-Tortosa E, Ayuso C, Suchowersky O, Trent RJ, McCusker E, Novelletto A, Frontali M, Jones R, Ashizawa T, Frank S, Saint-Hilaire MH, Hersch SM, Rosas HD, Lucente D, Harrison MB, Zanko A, Abramson RK, Marder K, Sequeiros J, MacDonald ME, Gusella JF. Am J Hum Genet. 2012 Mar 9;90(3):434-44. Epub 2012 Mar 1.

CAG repeat expansion in Huntington disease determines age at onset in a fully dominant fashion. Lee JM, Ramos EM, Lee JH, Gillis T, Mysore JS, Hayden MR, Warby SC, Morrison P, Nance M, Ross CA, Margolis RL, Squitieri F, Orobello S, Di Donato S, Gomez-Tortosa E, Ayuso C, Suchowersky O, Trent RJ, McCusker E, Novelletto A, Frontali M, Jones R, Ashizawa T, Frank S, Saint-Hilaire MH, Hersch SM, Rosas HD, Lucente D, Harrison MB, Zanko A, Abramson RK, Marder K, Sequeiros J, Paulsen JS; PREDICT-HD study of the Huntington Study Group (HSG), Landwehrmeyer GB; REGISTRY study of the European Huntington’s Disease Network, Myers RH; HD-MAPS Study Group, Macdonald ME, Gusella JF; COHORT study of the HSG. Neurology. 2012 Mar 6;78(10):690-5. Epub 2012 Feb 8.

Association of cumulative lead exposure with Parkinson’s disease. Weisskopf MG, Weuve J, Nie H, Saint-Hilaire MH, Sudarsky L, Simon DK, Hersh B, Schwartz J, Wright RO, Hu H. Environ Health Perspect. 2010 Nov;118(11):1609-13.

Self-management rehabilitation and health-related quality of life in Parkinson’s disease: a randomized controlled trial. Tickle-Degnen L, Ellis T, Saint-Hilaire MH, Thomas CA, Wagenaar RC. Mov Disord. 2010 Jan 30;25(2):194-204.

Seshadri S, Beiser A, Pikula A, Himali JJ, Kelly-Hayes M, Debette S, DeStefano AL, Romero JR, Kase CS, Wolf PA. Parental occurrence of stroke and risk of stroke in their children: the Framingham study. Circulation. 2010; 121:1304-12.

Debette S, Beiser A, DeCarli C, Au R, Himali JJ, Kelly-Hayes M, Romero JR, Kase CS, Wolf PA, Seshadri S. Association of MRI markers of vascular brain injury with incident stroke, mild cognitive impairment, dementia, and mortality: the Framingham Offspring study. Stroke. 2010; 4:600-606.

Debette S, Beiser A, Hoffmann U, DeCarli C, O’Donnell CJ, Massaro JM, Au R, Himali JJ, Wolf PA, Fox CS, Seshadri S. Visceral fat is associated with lower brain volume in healthy middle-aged adults. Ann Neurol. 2010; 68:136-144.

Seshadri S, Fitzpatrick AL, Ikram MA, DeStefano AL, Gudnason V, Boada M, Bis JC, Smith AV, Carassquillo MM, Lambert JC, Harold D, Schrijvers EM, Ramirez-Lorca R, Debette S, Longstreth WT Jr, Janssens AC, Pankratz VS, Dartigues JF, Hollingworth P, Aspelund T, Hernandez I, Beiser A, Kuller LH, Koudstaal PJ, Dickson DW, Tzourio C, Abraham R, Antunez C, Du Y, Rotter JI, Aulchenko YS, Harris TB, Petersen RC, Berr C, Owen MJ, Lopez-Arrieta J, Varadarajan BN, Becker JT, Rivadeneira F, Nalls MA, Graff-Radford NR, Campion D, Auerbach S, Rice K, Hofman A, Jonsson PV, Schmidt H, Lathrop M, Mosley TH, Au R, Psaty BM, Uitterlinden AG, Farrer LA, Lumley T, Ruiz A, Williams J, Amouyel P, Younkin SG, Wolf PA, Launer LJ, Lopez OL, van Duijn CM, Breteler MM; CHARGE Consortium; GERAD1 Consortium; EADI1 Consortium. Genome-wide analysis of genetic loci associated with Alzheimer disease. JAMA. 2010; 303:1832-40.

Lieb W, Beiser AS, Vasan RS, Tan ZS, Au R, Harris TB, Roubenoff R, Auerbach S, DeCarli C, Wolf PA, Seshadri S. Association of plasma leptin levels with incident Alzheimer disease and MRI measures of brain aging. JAMA. 2009; 302:2565-72.

Ikram MA, Seshadri S, Bis JC, Fornage M, DeStefano AL, Aulchenko YS, Debette S, Lumley T, Folsom AR, van den Herik EG, Bos MJ, Beiser A, Cushman M, Launer LJ, Shahar E, Struchalin M, Du Y, Glazer NL, Rosamond WD, Rivadeneira F, Kelly-Hayes M, Lopez OL, Coresh J, Hofman A, DeCarli C, Heckbert SR, Koudstaal PJ, Yang Q, Smith NL, Kase CS, Rice K, Haritunians T, Roks G, de Kort PLM, Taylor KD, de Lau LM, Oostra BA, Uitterlinden AG, Rotter JI, Boerwinkle E, Psaty BM, Mosley TH, van Duijn CM, Breteler MB, Longstreth WT Jr., Wolf PA. Genome-wide Association Studies of Incident Total Stroke and Ischemic Stroke: Meta-analysis and Replication from the CHARGE Consortium. New Engl J Med 2009; 360:1718-1728.

Debette S, Wolf PA, Beiser A, Au R, Himali JJ, Pikula A, Auerbach S, DeCarli C, Seshadri S. Association of parental dementia with cognitive and brain MRI measures in middle-aged adults. Neurology. 2009; 73:2071-2078.

Tan ZS, Beiser AS, Vasan RS, Roubenoff R, Dinarello CA, Harris TB, Benjamin EJ, Au R, Kiel DP, Wolf PA, Seshadri S. Inflammatory markers and the risk of Alzheimer’s disease: The Framingham Study. Neurology 2007;68:1902-1908.

Wolf PA, Beiser A, Elias MF, Au R, Vasan RS, Seshadri S. Relation of Obesity to Cognitive Function: Importance of Central Obesity and Synergistic Influence of Concomitant Hypertension. The Framingham Heart study. Current Alzheimer Research 2007;4:111-116.

MF Elias, LM Sullivan, EJ. Benjamin, PK Elias, RB D’Agostino, Sr., PA Wolf, Seshadri S, Au R, Vasan RS. Left Ventricular Mass, Blood Pressure and Lowered Cognitive Performance in the Framingham Offspring. Hypertension. 2007;49:439-45.

Jefferson AL, Massaro JM, Wolf PA, Seshadri S, Au R, Vasan R, Larson MG, Meigs JB, Keaney JF, Lipinska I, Kathiresan S, Benjamin EJ, DeCarli C.Inflammatory Biomarkers are Associated with Total Brain Volume: The Framingham Heart Study. Neurology 2007;68:1032-1038.

Seshadri S, Beiser A, et al. Lifetime risk of stroke and dementia. Stroke 2006; 37(2):345-50.

Seshadri S. Elevated plasma homocysteine levels: risk factor or risk marker for the development of dementia and Alzheimer’s disease? J Alz Dis 2006;9:393-8.

Elias MF, Sullivan LM, Elias PK, Vasan RS, D’Agostino RB, Seshadri S, Au R, Wolf PA, Benjamin EJ. Atrial fibrillation is associated with lower cognitive performance in the Framingham Offspring men. Journal of Stroke and Cerebrovascular Diseases 2006;15:214-222.

Seshadri S, Wolf PA, Besier A, Elias MF, Au R, Kase CS, D’Agostino RB, DeCarli C. Stroke Risk Profile, Brain Volume and Cognitive Function: The Framingham Offspring Study. Neurology 2004;63: 1591-99. Akomolafe A, Beiser AS, Meigs JB, Au R, Green RC, Farrer LA, Wolf PA, Seshadri S. Diabetes mellitus and risk of developing Alzheimer’s dementia: results from the Framingham Study. Arch Neurol 2006; 63:1551-5.

Au R, Massaro JM, Wolf PA, Young ME. Beiser AS, Seshadri S, D’Agostino RB, DeCarli C. Association of white matter hyperintensity volume with cognitive functioning- The Framingham Heart Study. Arch Neurol 2006;63:246-250.

McKee AC, Au R, Cabral HJ, Kowall NW, Seshadri S, Kubilus CA, Drake J, Drake BS, Wolf PA. Pathological involvement of the visual association cortex in cognitively intact, mildly impaired and demented subjects with Alzheimer’s Disease. Neuropathol Exp Neurol. 2006;65:621-30.

Brown, L.B., Stern, R.A., Cahn-Weiner, D.A., Rogers, B., Davis, M.A., Lannon, M.C., Maxwell, C., Souza, T., White, T., & Ott, B.R. (2005). Driving Scenes test of the Neuropsychological Assessment Battery (NAB) and on-road driving performance in aging and very mild dementia. Archives of Clinical Neuropsychology, 20, 209-215.

Jefferson, A.L., Wong, S., Bolen, E., Ozonoff, A., Green, R.C., & Stern, R.A. (2006). Cognitive correlates of HVOT performance differ between patients with mild cognitive impairment and normal controls. Archives of Clinical Neuropsychology, 21, 405-412.

Westervelt, H.J., Brown, L.B, Tremont, G., Javorsky, D.J., & Stern, R.A. (2006). Patient and family perceptions of the neuropsychological evaluation: How Are We Doing? The Clinical Neuropsychologist, 1385-4046

Bhalla, R.K., Papandonatos, G.D., Stern, R.A., & Ott, B.R. (2007). Alzheimer’s disease patients’ anxiety prior to and following a standardized on-road driving test. Alzheimer’s and Dementia, 3, 33-39.

Ropacki, S.A.L., Bert, A.A., Ropacki, M.T., Rogers, B.L., & Stern, R.A. (2007). The influence of cognitive reserve on neuropsychological functioning after coronary artery bypass grafting (CABG). Archives of Clinical Neuropsychology,.22, 73-85.

Jefferson, A.L., Wong, S., Gracer, T.S. Ozonoff, A., Green, R.C., & Stern, R.A. (in press). Geriatric norms for an abbreviated version of the Boston Naming Test. Applied Neuropsychology.

Posternak, M.A., Novak, S.P., Stern, R.A., Hennessey, J.V., Joffe, R., Prange, A.J. Jr, & Zimmerman, M. (in press). A pilot effectiveness study: placebo-controlled trial of adjunctive L-triiodothyronine (T3) used to accelerate and potentiate the antidepressant response. The International Journal of Neuropsychopharmacology.

Michaelides, C., and Wiesman, J., Letter to the Editor: Subacute Combined Degeneration of the Spinal Cord in a Young African-American Male, Southern Medical Journal, Vol 99 (1); 1311, 2006

Berk JL, Wiesman JF, Skinner M, Sanchorawala V. Diaphragm paralysis in primary systemic amyloidosis. Amyloid. 2005 Sep;12(3):193-6.

Wiesman, J. “Overview of Overactive Bladder”, an article review, Journal Watch, May, 2004.

Tan ZS, Seshadri S, Beiser A, Zhang Y, Felson D, Hannan MT, Au R, Wolf PA, Kiel DP. Bone Mineral Density and the Risk of Alzheimer’s Disease. Arch Neurol 2005;62(1):107-111. [PMID: 15642856],

Elias PK, Elias MF, D’Agostino RB, Sullivan LM, Wolf PA Serum Cholesterol and Cognitive Performance in the Framingham Heart Study. Psychosom Med 2005;67(1):24-30. [PMID: 15673620]

Radziszewska B., Hart RG, Wolf PA, D’Agostino RB, Sr., Cutler JA. Clinical Research in Primary Stroke Prevention: Needs, Opportunities, and Challenges. Neuroepidemiology. 2005;25(2):91-104. [PMID: 15956806]

Elias MF, Sullivan LM, D’Agostino RB, Elias PK, Jacques PF, Selhub J, Seshadri S, Au R, Beiser A, Wolf PA. Homocysteine and Cognitive Performance in the Framingham Offspring Study: Age is Important. Am J Epidemiol 2005;162(1):644-653. [PMID: 16107567]

Terry DF, Pencina M, Vasan RS, Murabito JM, Wolf PA, Kelly-Hayes M, Levy D, D’Agostino RB, Sr,. Benjamin E. Cardiovascular Risk Factors Predictive for Survival and Morbidity-Free Survival in the Oldest Old Framingham Heart Study Participants. J Am Geriatr Soc 2005; 53(11):1944-1950. [PMID 16274376]

Lessov-Schlaggar CN, Reed T, Swan GE, Krasnow RE, DeCarli C, Marcus R, Holloway L, Wolf PA, Carmelli D. Association of Sex Steroid Hormones with Brain Morphology and Cognition in Healthy Elderly Men. Neurology, 2005;65(10):1591-1596. [PMID: 16301487]

Elias MF, Elias PK, Sullivan LM, Wolf PA, D’Agostino RB. Obesity, Diabetes and Cognitive Deficit: The Framingham Study. Neurobiol Aging, 2005;26S1:S11-S16. [PMID: 16223549]

Babikian VL, Wolf PA. Invited Letter to the Editor. Retinal and Cerebral Microembolism During On-Pump and Off-Pump Coronary Artery Bypass Graft Surgery. Circulation 2005;112(25):3816-3817. [PMID: 16365204]

DeStefano AL, Atwood L, Massaro JM, Heard-Costa N, Beiser A, Au R, Wolf P, DeCarli C. Genome-wide Scan for White Matter Hyperintensity: The Framingham Heart Study. Stroke 2006;37(1):77-81 [PMID: 16322484].

Najarian RM, Sullivan LM, Kannel WB, Wilson PF, D’Agostino RB, Wolf PA. Metabolic Syndrome Compared with Type 2 Diabetes Mellitus as a Risk Factor for Stroke: The Framingham Study. Arch Intern Med 2006;166(1):106-111. [PMID 16401818]

Seshadri S, Beiser A, Kelly-Hayes M, Kase CS, Au R, Wolf PA. The Lifetime Risk of Stroke: Estimates from the Framingham Study. Stroke 2006, 37(2):345-350. [PMID: 16397184]

Au R, Massaro JM, Wolf PA, Young ME, Beiser A, Seshadri S, D’Agostino RB, DeCarli C. Association of White Matter Hyperintensity Volume with Decreased Cognitive Functioning: The Framingham Heart Study. Arch Neurol, 2006;63(2):246-250. [PMID: 16476813]

Lloyd-Jones D, Leip EP, Larson MG, D’Agostino RB, Beiser A, Wilson PWF, Wolf PA, Levy D. Prediction of Lifetime Risk for Cardiovascular Disease by Risk Factor Burden at 50 Years of Age. Circulation 2006;113(6):791-798. [PMID: 16461820]

Elosua R, Ordovas JM, Cupples LA, Lai CQ, Demissie S, Fox CS, Polak JF, Wolf PA, D’Agostino RB, O’Donnell CJ. Variants at the APOA5 Locus, Association with Carotid Atherosclerosis and Modification by Obesity: The Framingham Study. J Lipid Res 2006;47(5):990-996. [PMID: 16474174]

Najarian RM, Sullivan LM, Kannel WB, Wilson PWF, D’Agostino RB, Wolf PA. Reply to Letter to the Editor. Stroke, Obstructive Sleep Apnea, and Disorders of Glucose Metabolism. Arch Intern Med 2006;166:1418-1419.

McKee AC, Au R, Cabral HJ, Kowall NW, Seshadri S, Kubilus CA, Drake J, Wolf PA. Visual Association Pathology in Preclinical Alzheimer Disease. J Neuropathol Exp Neurol 2006;65;(6):621-630. [PMID: 16783172]

Elias MF, Sullivan LM, Elias PK, Vasan RS, D’Agostino RB Sr., Seshadri S, Au R, Wolf PA, Benjamin EJ. Atrial Fibrillation Is Associated With Lower Cognitive Performance in the Framingham Offspring Men. J Stroke and Cerebrovascular Disease, 2006;15 (5):214-222.

Elosua R, Cupples LA, Fox CS, Polak JF, D’Agostino RB, Wolf PA, O’Donnell CJ, Ordovas JM. Association Between Well-Characterized Lipoprotein-Related Genetic Variants and Carotid Intimal Medial Thickness and Stenosis: The Framingham Heart Study. Atherosclerosis 2006;189(1):222-228. [PMID: 16430904]

Schaefer EJ, Bongard V, Beiser A, Lamon-Fava S, Au R, Tucker KL, Kyle D, Wilson PWF, Wolf PA. Plasma Phosphotidylcholine Docosahexaenoic AcidContent and Risk of Dementia and Alzheimer Disease: The Framingham Heart Study. Arch Neurol 2006;63:1545-1550. [PMID: 17101822]

Akomolafe A, Beiser A, Meigs J, Au R, Green RC, Farrer LA, Wolf PA, Seshadri S. Diabetes Mellitus and Risk of Developing Alzheimer’s Dementia: Results from the Framingham Study. Arch Neurol 2006;63:1551-1555. [PMID: 17101823]

Carandang R, Seshadri S, Beiser A, Kelly-Hayes M , Kase CS, Kannel WB, Wolf PA. Trends in Incidence, Lifetime Risk, Severity, and 30-day Mortality of Stroke Over the Past 50 Years: The Framingham Study. JAMA 2006;296;24:2939-2946. [PMID: 17190894]

Lessov-Schlaggar CN, Swan GE, Reed T, Wolf PA, Carmelli D. Longitudinal Genetic Analysis of Executive Function in Elderly Men. Neurobiol Aging 2006; Sep 9. [PMID: 16965841]

Wolf PA. Lipids and Ischemic Stroke. Journal Watch 2007;9:1;1-2.

Salaycik KJ, Kelly-Hayes M, Beiser A, Nguyen A-H, Brady SM, Kase CS, Wolf PA. Depressive Symptoms and Risk of Stroke: The Framingham Study. Stroke 2007;38:16-21. [PMID: 17138952]

Kathiresan S, Larson MG, Keyes MJ, Polak JF, Wolf PA, D’Agostino RB, Jaffer FA, Clouse ME, Levy D, Manning WJ, O’Donnell CJ. Assessment by Cardiovascular Magnetic Resonance, Electron Beam Computed tomography, and Carotid Ultrasonography of the distribution of Subclinical Atherosclerosis Across Framingham Risk Strata. Am J Cardiol 2007;99(3):310-314. [PMID: 17261388]

Elias MF, Sullivan LM, Elias Pk, D’Agostino Sr RB, Wolf PA, Seshadri S, Au R, Benjamin EJ, Vasan RJ. Left Ventricular Mass, Blood Pressure, and Lowered Cognitive Performance in the Framingham Offspring. Hypertension, March 2007;49:439-445. [PMID 17224472]

Jefferson AL, Massaro JM, Wolf PA, Seshadri S, Au R, Vasan RS, Larson MG, Meigs JB, Keaney JF, Lipinska I, Kathiresan S, Benjamin EJ, DeCarli C. Inflammatory Biomarkers Are Associated with Total Brain Volume: The Framingham Heart Study. Neurology 2007;68:1032-1038 [PMID: 17389308].

Wolf PA, Beiser A, Elias MF, Au R, Vasan RS, Seshadri S. Relation of Obesity to Cognitive Function: Importance of Central Obesity and Synergistic Influence of Concomitant Hypertension. The Framingham Heart Study. Curr Alzheimer Res 2007;4;2:111-116. [PMID: 17430232]

Terry DF, Evans JC, Pencina MJ, Murabito JM, Vasan RS, Wolf PA, Kelly-Hayes M, Levy D, D’Agostino Sr. RB, Benjamin EJ. Characteristics of Framingham Offspring Participants With Long-Lived Parents. Arch Intern Med 2007;167:438-444. [PMID: 17353490]

Splansky GL, Corey D, Yang Q, Atwood LD, Cupples LA, Benjamin EJ, D’Agostino Sr. RB, Fox CS, Larson MG, Murabito JM, O’Donnell CJ, Vasan RS, Wolf PA, Levy D. The Third Generation Cohort of the National Heart, Lung and Blood Institute’s Framingham Heart Study: Design, Recruitment and Initial Examination. Am J Epidemiol 2007;165:1328-1335. [PMID: 17372189]

Ingelsson E, Sullivan LM, Murabito JM, Fox CS, Benjamin EJ, Polak JF, Meigs JB, Keyes MJ, O’Donnell CJ, Wang TJ, D’Agostino Sr. RB, Wolf PA, Vasan RS. Prevalence and Prognostic Impact of Subclinical Cardiovascular Disease in Individuals with the Metabolic Syndrome and Diabetes. Diabetes 2007;56:1718-1726. PMID: 17369522].

Tan ZS, Beiser AS, Vasan RS, Roubenoff R, Dinarello CA, Harris TB, Benjamin EJ, Au R, Kiel DP, Wolf PA, Seshadri S. Inflammatory Markers and the Risk of Alzheimer Disease: The Framingham Study. Neurology 2007;68:1902-1908.

Kelly-Hayes M, Wolf PA. Response to Letter by Salvador Vale, M.D. to the Editor on Depressive Symptoms and Risk of Stroke: The Framingham Study. Stroke June, 2007;38:e35.

Carandang R, Seshadri S, Beiser A, Kelly-Hayes M, Kase CS, Kannel WB, Wolf PA. Trends in Stroke Over the Past 50 Years. Cardiology Review, August, 2007.

Seshadri S, DeStefano AL, Au R, Massaro JM, Beiser AS, Kelly-Hayes M, Kase CS, D’Agostino Sr RB, DeCarli C, Atwood LD, Wolf PA. Genetic Correlates of Brain Aging on MRI and Cognitive Test Measures: A Genome-Wide Association and Linkage Analysis in the Framingham Study. BMC Medical Genetics 2007, 8(Suppl 1):S15 [PMID:17903297]. PMCID: PMC1995608

Ikram MA, Seshadri S, Bis JC, Fornage M, DeStefano AL, Aulchenko YS, Debette S, Lumley T, Folsom AR, van den Herik EG, Bos MJ, Beiser A, Cushman M, Launer LJ, Shahar E, Struchalin M, Du Y, Glazer NL, Rosamond WD, Rivadeneira F, Kelly-Hayes M, Lopez OL, Coresh J, Hofman A, DeCarli C, Heckbert SR, Koudstaal PJ, Yang Q, Smith NL, Kase CS, Rice K, Haritunians T, Roks G, de Kort PL, Taylor KD, de Lau LM, Oostra BA, Uitterlinden AG, Rotter JI, Boerwinkle E, Psaty BM, Mosley TH, van Duijn CM, Breteler MM, Longstreth WT Jr, Wolf PA. Genomewide association studies of stroke. N Engl J Med. 2009;360(17):1718-28. [PMID: 19369658]. PMCID: PMC276834.

Debette S, Wolf PA, Beiser AS, Au R, Himali JJ, Pikula A, Auerbach S, DeCarli CS, Seshadri S. Association of Parental Dementia with Cognitive and Brain MRI Measures in Middle-Aged Adults. Neurology. 2009;73:2071-2078. [PMID: 20007524]. PMCID: PMC2790222.

Seshadri S, Fitzpatrick AL, Ikram MA, DeStefano AL, Gudnason V, Bis JC, Smith AV, Carassquillo MM, Lambert JC, Harold D, Schrijvers EM, Debette S, Longstreth WT, Janssens C, Pankratz S, Dartigues JF, Hollinhworth P, Aspelund T, Beiser A, Kuller LH, Koudstaal PJ, Dickson DW, Tzourio C, Abraham R, Du Y, Rotter JI, Aulchenko YS, Harris TB, Petersen RC, Berr C, Owen MJ, Varadarajan BN, Becker JT, Rivadeneira F, Nalls MA, Graff-Radford NR, Campion D, Auerbach S, Rice K, Hofman A, Jonsson PV, Schmidt H, Lathrop M, Mosley TH, Au R, Psaty BM, Uitterlinden AG, Farrer LA, Lumley T, Williams J, Amouyel P, Younkin SG, Wolf PA, Launer LJ, Lopez O, van Duijn CM, Breteler MMB. Genome-wide Association Studies of Alzheimer’s Disease. Lancet. 2010 May 12; 303(18):1832-40. [PMID: 20460622]. NIHMSID: 208236

Debette S, Beiser A, Hoffmann U, Decarli C, O’Donnell CJ, Massaro JM, Au R, Himali JJ, Wolf PA, Fox CS, Seshadri S. Visceral fat is associated with lower brain volume in healthy middle-aged adults. Ann Neurol. 2010 Aug;68(2):136-44. [PMID: 20695006]. PMCID: PMC2933649.

Primary teaching affiliate
of BU School of Medicine