Robert A. Stern, Ph.D.

Professor of Neurology, Neurosurgery, and Anatomy & Neurobiology
Clinical Core Director, BU Alzheimer’s Disease and CTE Center
Boston University School of Medicine
Robinson Complex, Suite 7800
72 East Concord Street,
Boston, MA 02118-2526

Research Phone: 617-638-5678
Clinical Phone: 617-638-7100
Fax: 617-414-1197
Web: www.bu.edu/alzresearch

Education:

Undergraduate: Wesleyan University, Psychology, Bachelor of Arts, 1980; Honors in Psychology; Heideman Prize for Community Contribution.

Graduate School: University of Rhode Island, Psychology, Master of Arts, 1984; Elected to Membership of Psi Chi National Honor Society in Psychology

University of Rhode Island, Clinical Psychology (Clinical Neuropsychology Specialization), Ph.D., 1988, Dissertation: “Mood Disorders following Stroke.” Elected to Membership of Phi Kappa Phi National Honor Society

Research Expertise and Professional Interests:

Dr. Robert Stern is Professor of Neurology, Neurosurgery, and Anatomy and Neurobiology at Boston University School of Medicine, where he is also Director of the Clinical Core of the BU Alzheimer’s Disease Center (one of only 27 centers funded by the National Institutes of Health, NIH), and Director of Clinical Research for the BU Chronic Traumatic Encephalopathy (CTE) Center.  A major focus of his research involves the long-term effects of repetitive brain trauma in athletes, including the neurodegenerative disease, CTE.  He has funding from NIH and the Department of Defense for his work on developing methods of detecting and diagnosing CTE during life, as well as examining potential genetic and other risk factors for this disease.  His other major areas of funded research include the assessment and treatment of Alzheimer’s disease, the cognitive effects of chemotherapy in the elderly, thyroid-brain relationships, and driving and dementia.  Dr. Stern has also published on various aspects of cognitive assessment and is the senior author of many widely used neuropsychological tests, including the Neuropsychological Assessment Battery (NAB).  Dr. Stern has received several NIH and other national grants, has published over 250 journal articles, chapters, and abstracts, and is a Fellow of both the American Neuropsychiatric Association and the National Academy of Neuropsychology.  He is on several editorial boards and is on the Medical and Scientific Advisory Boards of the MA/NH Chapter of the Alzheimer’s Association and Concussion Legacy Foundation, and is also a member of the Mackey-White Traumatic Brain Injury Committee of the NFL Players Association. Dr. Stern has testified before the US Senate Special Committee on Aging. He appears frequently in national and international print and broadcast media for his work on CTE and AD.  He also appears in the feature length documentaries, “League of Denial” (PBS Frontline, 2013), “Head Games” (2012), and “I Remember Better When I Paint” (2009).

Recent Publications:

Gavett BE, Gurnani AS, Saurman JL, Chapman KR, Steinberg EG, Martin B, Chaisson CE, Mez J, Tripodis Y, Stern RA. Practice Effects on Story Memory and List Learning Tests in the Neuropsychological Assessment of Older Adults. PLoS One. 2016 Oct 6;11(10):e0164492. doi: 10.1371/journal.pone.0164492.

Stern RA. Cerebrospinal Fluid Biomarkers in Postconcussion Syndrome: Measuring Neuronal Injury and Distinguishing Individuals at Risk for Persistent Postconcussion Syndrome or Chronic Traumatic Encephalopathy. JAMA Neurol. 2016 Sep 19. doi: 10.1001/jamaneurol.2016.3169. [Epub ahead of print]

Stern RA, Abularach LM, Seichepine DR, Alosco ML, Gavett BE, Tripodis Y. Office-Based Assessment of At-Risk Driving in Older Adults With and Without Cognitive Impairment. J Geriatr Psychiatry Neurol. 2016 Sep 19. pii: 0891988716666378. [Epub ahead of print]

Stern RA, Dasarathy S, Mozdziak PE. Ammonia elicits a different myogenic response in avian and murine myotubes. In Vitro Cell Dev Biol Anim. 2016 Aug 29. [Epub ahead of print]

Alosco ML, Mez J, Kowall NW, Stein TD, Goldstein LE, Cantu RC, Katz DI, Solomon TM, Kiernan PT, Murphy L, Abdolmohammadi B, Daneshvar D, Montenigro PH, Nowinski CJ, Stern RA, McKee AC. Cognitive Reserve as a Modifier of Clinical Expression in Chronic Traumatic Encephalopathy: A Preliminary Examination. J Neuropsychiatry Clin Neurosci. 2016 Aug 19:appineuropsych16030043. [Epub ahead of print]

Besser LM, Alosco ML, Ramirez Gomez L, Zhou XH, McKee AC, Stern RA, Gunstad J, Schneider JA, Chui H, Kukull WA. Late-Life Vascular Risk Factors and Alzheimer Disease Neuropathology in Individuals with Normal Cognition. J Neuropathol Exp Neurol. 2016 Oct;75(10):955-962. Epub 2016 Aug 11.

Mandelblatt JS, Clapp JD, Luta G, Faul LA, Tallarico MD, McClendon TD, Whitley JA, Cai L, Ahles TA, Stern RA, Jacobsen PB, Small BJ, Pitcher BN, Dura-Fernandis E, Muss HB, Hurria A, Cohen HJ, Isaacs C. Long-term trajectories of self-reported cognitive function in a cohort of older survivors of breast cancer: CALGB 369901 (Alliance). Cancer. 2016 Jul 22. doi: 10.1002/cncr.30208. [Epub ahead of print]

Alosco ML, Jarnagin J, Tripodis Y, Platt M, Martin B, Chaisson CE, Baugh CM, Fritts NG, Cantu RC, Stern RA. Olfactory Function and Associated Clinical Correlates in Former National Football League Players. J Neurotrauma. 2016 Aug 11. [Epub ahead of print]

Galetta KM, Chapman KR, Essis MD, Alosco ML, Gillard D, Steinberg E, Dixon D, Martin B, Chaisson CE, Kowall NW, Tripodis Y, Balcer LJ, Stern RA. Screening Utility of the King-Devick Test in Mild Cognitive Impairment and Alzheimer Disease Dementia. Alzheimer Dis Assoc Disord. 2016 Jun 13. [Epub ahead of print]

Feke GT, Hyman BT, Stern RA, Pasquale LR. Retinal blood flow in mild cognitive impairment and Alzheimer’s disease. Alzheimers Dement (Amst). 2015 Apr 23;1(2):144-51. doi: 10.1016/j.dadm.2015.01.004. eCollection 2015 Jun.

Stern RA, Seichepine D, Tschoe C, Fritts NG, Alosco ML, Berkowitz O, Burke P, Howland J, Olshaker J, Cantu RC, Baugh CM, Holsapple JW. Concussion Care Practices and Utilization of Evidence-Based Guidelines in the Evaluation and Management of Concussion: A Survey of New England Emergency Departments. J Neurotrauma. 2016 May 19. [Epub ahead of print]

Montenigro PH, Alosco ML, Martin BM, Daneshvar DH, Mez J, Chaisson CE, Nowinski CJ, Au R, McKee AC, Cantu RC, McClean MD, Stern RA, Tripodis Y. Cumulative Head Impact Exposure Predicts Later-Life Depression, Apathy, Executive Dysfunction, and Cognitive Impairment in Former High School and College Football Players. J Neurotrauma. 2016 Mar 30. [Epub ahead of print]

Chapman KR, Bing-Canar H, Alosco ML, Steinberg EG, Martin B, Chaisson C, Kowall N, Tripodis Y, Stern RA. Mini Mental State Examination and Logical Memory scores for entry into Alzheimer’s disease trials. Alzheimers Res Ther. 2016 Feb 22;8:9. doi: 10.1186/s13195-016-0176-z.

Stern RA, Tripodis Y, Baugh CM, Fritts NG, Martin BM, Chaisson C, Cantu RC, Joyce JA, Shah S, Ikezu T, Zhang J, Gercel-Taylor C, Taylor DD. Preliminary Study of Plasma Exosomal Tau as a Potential Biomarker for Chronic Traumatic Encephalopathy. J Alzheimers Dis. 2016 Feb 10;51(4):1099-109. doi: 10.3233/JAD-151028.

Stern RA, Stamm JM. Author Response. Neurology. 2015 Sep 15;85(11):1008-10.

Mez J, Solomon TM, Daneshvar DH, Murphy L, Kiernan PT, Montenigro PH, Kriegel J, Abdolmohammadi B, Fry B, Babcock KJ, Adams JW, Bourlas AP, Papadopoulos Z, McHale L, Ardaugh BM, Martin BR, Dixon D, Nowinski CJ, Chaisson C, Alvarez VE, Tripodis Y, Stein TD, Goldstein LE, Katz DI, Kowall NW, Cantu RC, Stern RA, McKee AC. Assessing clinicopathological correlation in chronic traumatic encephalopathy: rationale and methods for the UNITE study. Alzheimers Res Ther. 2015 Oct 12;7(1):62. doi: 10.1186/s13195-015-0148-8.

Koerte IK, Hufschmidt J, Muehlmann M, Tripodis Y, Stamm JM, Pasternak O, Giwerc MY, Coleman MJ, Baugh CM, Fritts NG, Heinen F, Lin A, Stern RA, Shenton ME. Cavum Septi Pellucidi in Symptomatic Former Professional Football Players. J Neurotrauma. 2016 Feb 15;33(4):346-53. doi: 10.1089/neu.2015.3880. Epub 2015 Dec 15.

Koerte IK, Mayinger M, Muehlmann M, Kaufmann D, Lin AP, Steffinger D, Fisch B, Rauchmann BS, Immler S, Karch S, Heinen FR, Ertl-Wagner B, Reiser M, Stern RA, Zafonte R, Shenton ME. Cortical thinning in former professional soccer players. Brain Imaging Behav. 2015 Aug 19.

Stamm JM, Koerte IK, Muehlmann M, Pasternak O, Bourlas AP, Baugh CM, Giwerc MY, Zhu A, Coleman MJ, Bouix S, Fritts NG, Martin BM, Chaisson C, McClean MD, Lin AP, Cantu RC, Tripodis Y, Stern RA, Shenton ME. Age at First Exposure to Football Is Associated with Altered Corpus Callosum White Matter Microstructure in Former Professional Football Players. J Neurotrauma. 2015 Nov 15;32(22):1768-76. doi: 10.1089/neu.2014.3822.

Stein TD, Montenigro PH, Alvarez VE, Xia W, Crary JF, Tripodis Y, Daneshvar DH, Mez J, Solomon T, Meng G, Kubilus CA, Cormier KA, Meng S, Babcock K, Kiernan P, Murphy L, Nowinski CJ, Martin B, Dixon D, Stern RA, Cantu RC, Kowall NW, McKee AC. Beta-amyloid deposition in chronic traumatic encephalopathy. Acta Neuropathol. 2015 Jul;130(1):21-34. doi: 10.1007/s00401-015-1435-y.

Koerte IK, Lin AP, Willems A, Muehlmann M, Hufschmidt J, Coleman MJ, Green I, Liao H, Tate DF, Wilde EA, Pasternak O, Bouix S, Rathi Y, Bigler ED, Stern RA, Shenton ME. A review of neuroimaging findings in repetitive brain trauma. Brain Pathol. 2015 May;25(3):318-49. doi: 10.1111/bpa.12249. Review.

Koerte IK, Lin AP, Muehlmann M, Merugumala S, Liao H, Starr T, Kaufmann D, Mayinger M, Steffinger D, Fisch B, Karch S, Heinen F, Ertl-Wagner B, Reiser M, Stern RA, Zafonte R, Shenton ME. Altered Neurochemistry in Former Professional Soccer Players without a History of Concussion. J Neurotrauma. 2015 Sep 1;32(17):1287-93. doi: 10.1089/neu.2014.3715.

Lin AP, Ramadan S, Stern RA, Box HC, Nowinski CJ, Ross BD, Mountford CE. Changes in the neurochemistry of athletes with repetitive brain trauma: preliminary results using localized correlated spectroscopy. Alzheimers Res Ther. 2015 Mar 15;7(1):13. doi: 10.1186/s13195-015-0094-5. eCollection 2015.

Stamm JM, Bourlas AP, Baugh CM, Fritts NG, Daneshvar DH, Martin BM, McClean MD, Tripodis Y, Stern RA. Age of first exposure to football and later-life cognitive impairment in former NFL players. Neurology. 2015 Jan 28. pii: 10.1212/WNL.0000000000001358. [Epub ahead of print]

Riley DO, Robbins CA, Cantu RC, Stern RA. Chronic traumatic encephalopathy: Contributions from the Boston University Center for the Study of Traumatic Encephalopathy. Brain Inj. 2015;29(2):154-63. doi: 10.3109/02699052.2014.965215.

Montenigro PH, Corp DT, Stein TD, Cantu RC, Stern RA. Chronic traumatic encephalopathy: historical origins and current perspective. Annu Rev Clin Psychol. 2015;11:309-30. doi: 10.1146/annurev-clinpsy-032814-112814. Epub 2015 Jan 12. Review.

Andrikopoulos J, Montenigro PH, Stern RA. Clinical presentation of chronic traumatic encephalopathy. Neurology. 2014 Nov 18; 83(21):1991-3.

Montenigro PH, Baugh CM, Daneshvar DH, Mez J, Budson AE, Au R, Katz DI, Cantu RC, Stern RA. Clinical subtypes of chronic traumatic encephalopathy: literature review and proposed research diagnostic criteria for traumatic encephalopathy syndrome. Alzheimers Res Ther. 2014 Sep 24;6(5):68. doi: 10.1186/s13195-014-0068-z. eCollection 2014. Review.

Montenigro PH, Stern RA. Author response. Neurology. 2014 Nov 18; 83(21):1992-3.

Baugh CM, Robbins CA, Stern RA, McKee AC. Current understanding of chronic traumatic encephalopathy. Curr Treat Options Neurol. 2014 Sep;16(9):306. doi: 10.1007/s11940-014-0306-5. PubMed PMID: 25023937.

Mandelblatt JS, Stern RA, Luta G, McGuckin M, Clapp JD, Hurria A, Jacobsen PB, Faul LA, Isaacs C, Denduluri N, Gavett B, Traina TA, Johnson P, Silliman RA, Turner RS, Howard D, Van Meter JW, Saykin A, Ahles T. Cognitive impairment in older patients with breast cancer before systemic therapy: is there an interaction between cancer and comorbidity? J Clin Oncol. 2014 Jun 20;32(18):1909-18. doi: 10.1200/JCO.2013.54.2050. Epub 2014 May 19. PubMed PMID: 24841981.

Qiu WQ, Au R, Zhu H, Wallack M, Liebson E, Li H, Rosenzweig J, Mwamburi M, Stern RA. Positive association between plasma amylin and cognition in a homebound elderly population. J Alzheimers Dis. 2014;42(2):555-63. doi: 10.3233/JAD-140210.

Zhu H, Wang X, Wallack M, Li H, Carreras I, Dedeoglu A, Hur JY, Zheng H, Li H, Fine R, Mwamburi M, Sun X, Kowall N, Stern RA, Qiu WQ. Intraperitoneal injection of the pancreatic peptide amylin potently reduces behavioral impairment and brain amyloid pathology in murine models of Alzheimer’s disease. Mol Psychiatry. 2015 Feb;20(2):252-62. doi: 10.1038/mp.2014.17.

Robbins CA, Daneshvar DH, Picano JD, Gavett BE, Baugh CM, Riley DO, Nowinski CJ, McKee AC, Cantu RC, Stern RA. Self-reported concussion history: impact of providing a definition of concussion. Open Access J Sports Med. 2014 May 7;5:99-103. doi: 10.2147/OAJSM.S58005. eCollection 2014. PubMed PMID: 24891816.

Mez J, Stern RA, McKee AC. Chronic traumatic encephalopathy: where are we and where are we going? Curr Neurol Neurosci Rep. 2013 Dec;13(12):407. doi: 10.1007/s11910-013-0407-7. Review. PubMed PMID: 24136455.

Mandelblatt JS, Hurria A, McDonald BC, Saykin AJ, Stern RA, VanMeter JW, McGuckin M, Traina T, Denduluri N, Turner S, Howard D, Jacobsen PB, Ahles T; Thinking and Living With Cancer Study. Cognitive effects of cancer and its treatments at the intersection of aging: what do we know; what do we need to know? Semin Oncol. 2013 Dec;40(6):709-25. doi: 10.1053/j.seminoncol.2013.09.006. Review. PubMed PMID: 24331192.

Stern RA, Daneshvar DH, Baugh CM, Seichepine DR, Montenigro PH, Riley DO, Fritts NG, Stamm JM, Robbins CA, McHale L, Simkin I, Stein TD, Alvarez VE, Goldstein LE, Budson AE, Kowall NW, Nowinski CJ, Cantu RC, McKee AC. Clinical presentation of chronic traumatic encephalopathy. Neurology. 2013 Sep 24;81(13):1122-9. doi: 10.1212/WNL.0b013e3182a55f7f. Epub 2013 Aug 21. PubMed PMID: 23966253.

Seichepine DR, Stamm JM, Daneshvar DH, Riley DO, Baugh CM, Gavett BE, Tripodis Y, Martin B, Chaisson C, McKee AC, Cantu RC, Nowinski CJ, Stern RA. Profile of self-reported problems with executive functioning in college and professional football players. J Neurotrauma. 2013 Jul 15;30(14):1299-304. doi: 10.1089/neu.2012.2690. Epub 2013 Jul 11. PubMed PMID: 23421745.

Cardozo FT, Larsen IV, Carballo EV, Jose G, Stern RA, Brummel RC, Camelini CM, Rossi MJ, Simões CM, Brandt CR. In vivo anti-herpes simplex virus activity of a sulfated derivative of Agaricus brasiliensis mycelial polysaccharide. Antimicrob Agents Chemother. 2013 Jun;57(6):2541-9. doi: 10.1128/AAC.02250-12. Epub 2013 Mar 18. PubMed PMID: 23507287.

Joffe RT, Pearce EN, Hennessey JV, Ryan JJ, Stern RA. Subclinical hypothyroidism, mood, and cognition in older adults: a review. Int J Geriatr Psychiatry. 2013 Feb;28(2):111-8. doi: 10.1002/gps.3796. Epub 2012 Mar 13. Review. PubMed PMID: 22410877.

McKee AC, Stern RA, Nowinski CJ, Stein TD, Alvarez VE, Daneshvar DH, Lee HS, Wojtowicz SM, Hall G, Baugh CM, Riley DO, Kubilus CA, Cormier KA, Jacobs MA, Martin BR, Abraham CR, Ikezu T, Reichard RR, Wolozin BL, Budson AE, Goldstein LE, Kowall NW, Cantu RC. The spectrum of disease in chronic traumatic encephalopathy. Brain. 2013 Jan;136(Pt 1):43-64. doi: 10.1093/brain/aws307. Epub 2012 Dec 2. Erratum in: Brain. 2013 Oct;136(Pt 10):e255. PubMed PMID: 23208308.

Niewoehner PM, Henderson RR, Dalchow J, Beardsley TL, Stern RA, Carr DB. Predicting road test performance in adults with cognitive or visual impairment referred to a Veterans Affairs Medical Center driving clinic. J Am Geriatr Soc. 2012 Nov;60(11):2070-4. doi: 10.1111/j.1532-5415.2012.04201.x. Epub 2012 Oct 30. PubMed PMID: 23110784.

Gavett BE, Stern RA. Dementia has a categorical, not dimensional, latent structure. Psychol Aging. 2012 Sep;27(3):791-7; author reply 798-800. doi: 10.1037/a0027687. PubMed PMID: 22962922.

Pecoits E, Konhauser KO, Aubet NR, Heaman LM, Veroslavsky G, Stern RA, Gingras MK. Bilaterian burrows and grazing behavior at >585 million years ago. Science. 2012 Jun 29;336(6089):1693-6. doi: 10.1126/science.1216295. PubMed PMID: 22745427.

Baugh CM, Stamm JM, Riley DO, Gavett BE, Shenton ME, Lin A, Nowinski CJ, Cantu RC, McKee AC, Stern RA. Chronic traumatic encephalopathy: neurodegeneration following repetitive concussive and subconcussive brain trauma. Brain Imaging Behav. 2012 Jun;6(2):244-54. doi: 10.1007/s11682-012-9164-5. Review. PubMed PMID: 22552850.

Shenton ME, Hamoda HM, Schneiderman JS, Bouix S, Pasternak O, Rathi Y, Vu MA, Purohit MP, Helmer K, Koerte I, Lin AP, Westin CF, Kikinis R, Kubicki M, Stern RA, Zafonte R. A review of magnetic resonance imaging and diffusion tensor imaging findings in mild traumatic brain injury. Brain Imaging Behav. 2012 Jun;6(2):137-92. doi: 10.1007/s11682-012-9156-5. Review. PubMed PMID: 22438191.

Goldstein LE, Fisher AM, Tagge CA, Zhang XL, Velisek L, Sullivan JA, Upreti C, Kracht JM, Ericsson M, Wojnarowicz MW, Goletiani CJ, Maglakelidze GM, Casey N, Moncaster JA, Minaeva O, Moir RD, Nowinski CJ, Stern RA, Cantu RC, Geiling J, Blusztajn JK, Wolozin BL, Ikezu T, Stein TD, Budson AE, Kowall NW, Chargin D, Sharon A, Saman S, Hall GF, Moss WC, Cleveland RO, Tanzi RE, Stanton PK, McKee AC. Chronic traumatic encephalopathy in blast-exposed military veterans and a blast neurotrauma mouse model. Sci Transl Med. 2012 May 16;4(134):134ra60. doi: 10.1126/scitranslmed.3003716. PubMed PMID: 22593173.

Gavett BE, Lou KR, Daneshvar DH, Green RC, Jefferson AL, Stern RA. Diagnostic accuracy statistics for seven Neuropsychological Assessment Battery (NAB) test variables in the diagnosis of Alzheimer’s disease. Appl Neuropsychol Adult. 2012;19(2):108-15. doi: 10.1080/09084282.2011.643947. PubMed PMID: 23373577.

Gavett BE, Cantu RC, Shenton M, Lin AP, Nowinski CJ, McKee AC, Stern RA. Clinical appraisal of chronic traumatic encephalopathy: current perspectives and future directions. Curr Opin Neurol. 2011 Dec;24(6):525-31. doi: 10.1097/WCO.0b013e32834cd477. Review. PubMed PMID: 22045219.

Daneshvar DH, Riley DO, Nowinski CJ, McKee AC, Stern RA, Cantu RC. Long-term consequences: effects on normal development profile after concussion. Phys Med Rehabil Clin N Am. 2011 Nov;22(4):683-700, ix. doi: 10.1016/j.pmr.2011.08.009. Epub 2011 Sep 23. Review. PubMed PMID: 22050943.

Stern RA, Riley DO, Daneshvar DH, Nowinski CJ, Cantu RC, McKee AC. Long-term consequences of repetitive brain trauma: chronic traumatic encephalopathy. PM R. 2011 Oct;3(10 Suppl 2):S460-7. doi: 10.1016/j.pmrj.2011.08.008. Review. PubMed PMID: 22035690.

Ready RE, Carvalho JO, Green RC, Gavett BE, Stern RA. The structure and validity of self-reported affect in mild cognitive impairment and mild Alzheimer’s disease. Int Psychogeriatr. 2011 Aug;23(6):887-98. doi: 10.1017/S104161021100041X. Epub 2011 Mar 24. PubMed PMID: 21429280.

Primary teaching affiliate
of BU School of Medicine