Aleksandra Pikula, MD

Assistant Professor of NeurologyAleksandra Pikula
Boston University School of Medicine
72 East Concord Street, Neurology C-3
Boston, MA 02118

Phone: 617-638-8456
Fax: 617-638-5354
Email: alpikula@bu.edu

Medical School: University of Belgrade, School of Medicine (1995)
Internship: Queens Medical Center, Mount Sinai School of Medicine, New York University (2004)
Residency: Neurology, Boston University Medical Center (2007)
Clinical Fellowship: Vascular Neurology, Boston University Medical Center (2008)
Research Fellowship: Advanced Vascular Neurology, Boston University Medical Center & the Framingham Heart Study (2009)
Board Certifications: Vascular Neurology (2009), Neurology (2008), General Medicine (1997)
Special Interests: Cerebrovascular Disease, Stroke Risk Factors/Novel Biomarkers, Stroke in Young, Neuroepidemiology/Neurogenetics.

 

Recent Publications

Weinstein G, Beiser AS, Choi SH, Preis SR, Chen TC, Vorgas D, Au R, Pikula A, Wolf PA, Destefano AL, Vasan RS, Seshadri S.Serum Brain-Derived Neurotrophic Factor and the Risk for Dementia: The Framingham Heart Study. JAMA Neurol. 2013 Nov 25.

Pikula A, Beiser AS, Chen TC, Preis SR, Vorgias D, Decarli C, Au R, Kelly-Hayes M, Kase CS, Wolf PA, Vasan RS, Seshadri S.Serum Brain-Derived Neurotrophic Factor and Vascular Endothelial Growth Factor Levels Are Associated With Risk of Stroke and Vascular Brain Injury: Framingham Study.
Stroke 2013. Aug 8 (ahead of print)

Romero JR, Mercado M, Beiser AS, Pikula A, Seshadri S, Kelly-Hayes M, Wolf PA, Kase CS. Transient global amnesia and neurological events: the framingham heart study. Front Neurol 2013;4:47.

Shoamanesh A, Catanese L, Sakai O, Pikula A, Kase CS.Diffusion-Weighted imaging hyperintensities in intracerebral hemorrhage: Microinfarcts or microbleeds? Ann Neurol. 2013 Jan 29.

Romero JR, Preis SR, Beiser AS, DeCarli C, Lee DY, Viswanathan A, Benjamin EJ, Fontes J, Au R, Pikula A, Wang J, Kase CS, Wolf PA, Irrizary MC, Seshadri S.
Lipoprotein Phospholipase A2 and Cerebral Microbleeds in the Framingham Heart Study. Stroke September 2012

Enhancing Neuro Imaging Genetics through Meta-Analysis (ENIGMA) Consortium, Bis JC, Decarli C, Smith AV, van der Lijn F, Crivello F, Fornage M, Debette S, Shulman JM, Schmidt H, Srikanth V, Schuur M, Yu L, Choi SH, Sigurdsson S, Verhaaren BF, Destefano AL, Lambert JC, Jack CR Jr, Struchalin M, Stankovich J, Ibrahim-Verbaas CA, Fleischman D, Zijdenbos A, den Heijer T, Mazoyer B, Coker LH, Enzinger C, Danoy P, Amin N, Arfanakis K, van Buchem MA, de Bruijn RF, Beiser A, Dufouil C, Huang J, Cavalieri M, Thomson R, Niessen WJ, Chibnik LB, Gislason GK, Hofman A, Pikula A, Amouyel P, Freeman KB, Phan TG, Oostra BA, Stein JL, Medland SE, Vasquez AA, Hibar DP, Wright MJ, Franke B, Martin NG, Thompson PM; the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium, Nalls MA, Uitterlinden AG, Au R, Elbaz A, Beare RJ, van Swieten JC, Lopez OL, Harris TB, Chouraki V, Breteler MM, De Jager PL, Becker JT, Vernooij MW, Knopman D, Fazekas F, Wolf PA, van der Lugt A, Gudnason V, Longstreth WT Jr, Brown MA,
Bennett DA, van Duijn CM, Mosley TH, Schmidt R, Tzourio C, Launer LJ, Ikram MA, Seshadri S. Common variants at 12q14 and 12q24 are associated with hippocampal volume. Nat Genet. 2012;44(5):545-551. doi: 10.1038/ng.2237.

Pikula A, Beiser AS, Decarli C, Himali JJ, Debette S, Au R, Selhub J, Toffler  GH, Wang TJ, Meigs JB, Kelly-Hayes M, Kase CS, Wolf PA, Vasan RS, Seshadri S. Multiple biomarkers and risk of clinical and subclinical vascular brain injury: the framingham offspring study. Circulation. 2012;125(17):2100-7. Epub 2012 Mar 28.

Tan ZS, Harris WS, Beiser AS, Au R, Himali JJ, Debette S, Pikula A, Decarli C, Wolf PA, Vasan RS, Robins SJ, Seshadri S. Red blood cell ω-3 fatty acid levels and markers of accelerated brain aging. Neurology 2012;78(9):658-64.

Nguyen TN, Babikian VL, Romero JR, Pikula A, Kase CS, Jovin TG, Norbash AM. Intra-arterial treatment methods in acute stroke therapy. Frontiers in Endovascular and Interventional Neurology 2011;2:1-10.

Petrea RE, Koyfman F, Pikula A, Romero JR, Viereck J, Babikian VL, Kase CS, Nguyen TN. Acute Stroke, Catheter Related Venous Thrombosis, and Paradoxical Cerebral Embolism: Report of Two Cases. J Neuroimaging 2011;31.

Pikula A, Stefanidou M, Romero JR, Kase CS. Pure Motor Upper Limb Weakness and Infarction in the Precentral Gyrus: The Mechanism of Stroke. JIVN 2010 (in press).

Seshadri S, Beiser A, Pikula A, Himali JJ, Kelly-Hayes M, Debette S, DeStefano AL, Romero JR, Kase CS, Wolf PA. Parental occurrence of stroke and risk of stroke in their children: the Framingham study. Circulation 2010;121(11):1304-12.

Debette S, Wolf PA, Beiser A, Au R, Himali JJ, Pikula A, Auerbach S, Decarli C, Seshadri S. Association of parental dementia with cognitive and brain MRI measures in middle-aged adults.Neurology 2009;73(24):2071-8.

Romero JR,  Pikula A, Nguyen TN,  Nien YL,  Norbash A, Babikian VL. Cerebral Collateral Circulation in Carotid Artery Disease.Current Cardiology Reviews 2009;5(4);279-288.

Pikula A, Boger RH, Beiser A, Maas R, DeCarli C, Schwedhelm E, Du Y, Schulze F, Au R, Kelly-Hayes M, Kase CS, Vasan RS, Wolf PA, Seshadri S. Plasma Asymmetric dimethylarginine (ADMA) Levels are Associated with Silent Cerebral Infarcts: The Framingham Study. Stroke 2009;40(9):2959-64.

Romero JR, Pikula A. Carotid Artery Disease: Current Concepts on Endothelial Dysfunction and Matrix Remodeling. Current Drug Therapy 2009;4(3):202-213.

Pikula A, Almodovar JS, Nguyen T. Cerebral Arteriovenous Malformation in Hereditary Hemorrhagic Teleangiectasia. Neurology 2009;72(10):e45.

Romero JR, Morris J, Pikula A. Stroke prevention: modifying risk factors. Therapeutic Advances in Cardiovascular Disease 2008;2: 287-303.

Primary teaching affiliate
of BU School of Medicine