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Selected Publications

Murphy, G.J. and Leavitt A.D.  (1999)  A model for studying megakaryocyte development and biology.  Proc. Natl. Acad. Sci. USA,96,3065-3070.

Shiraga, M., Ritchie A., Aidoudi, S., Baron V., Wilcox, D., White G., Ybarrondo, B., Murphy, G., Leavitt, A., Shattil, S.  (1999)  Primary megakaryocytes reveal a role for transcription factor NF-E2 in integrin alpha IIb beta3 signaling.  J Cell Biol,147,1419-1430.

Berlanga O, Bobe R, Murphy G, Leduc M, Bon C, Barry FA, Gibbins JM, Garcia P, Frampton J, Watson SP.  (2000) Expression of the collagen receptor glycoprotein VI during megakaryocyte differentiation.  Blood, 96(8),2740-2745.

Gaur  M, Murphy GJ, deSauvage FJ, and Leavitt AD. (2001)   Characterization of Mpl mutants using primary megakaryocyte-lineage cells from mpl-/- mice:  a new system for Mpl structure-function studies.  Blood, 97(6), 1653-1661.

Emambokus NR, Murphy GJ, and Frampton J.  (2002) Manipulation of gene expression in megakaryocytes, in Platelets and Megakaryocytes:  Methods and Protocols, Editors J.M. Gibbins and M.P. Mahaut-Smith.

Gaur M, Murphy GJ, Frampton J, and Leavitt AD.  (2002) Using retroviruses to express genes in primary megakaryocyte lineage cells, in Platelets and Megakaryocytes:  Methods and Protocols, Editors J.M. Gibbins and M.P. Mahaut-Smith.

Murphy GJ, Göttgens B, Vegiopoulos Sanchez MJ, Leavitt AD, Watson SP, Green AR, and Frampton J. (2003)  Manipulation of mouse hematopoietic progenitors by specific retroviral infection. Journal of Biological Chemistry, 44, 43556-43563.

Gottgens B, Broccardo C, Sanchez MJ, Deveaux S, Murphy G, Gothert JR, Kotsopoulou E, Kinston S, Delaney L, Piltz S, Barton LM, Knezevic K, Erber WN, Begley CG, Frampton J, Green AR.  (2004)  The scl+18/19 stem cell enhancer is not required for hematopoiesis:  identification of a 5′ bifunctional hematopoietic-endothelial enhancer bound by Fli-1 and Elf-1.  Mol Cell Biol., 24, 1870-1883.

Murphy GJ, Mostoslavsky G, Kotton DN,  Mulligan RC.  (2006)  Exogenous control of mammalian gene expression via modulation of translational termination.  Nature Medicine, 9, 1093-1099.

Sommer CA, Stadtfeld M, Murphy GJ, Hochedlinger K, Kotton DN, and Mostoslavsky G.  (2008)  iPS generation using a single lentiviral stem-cell cassette.  Stem Cells, December 18 (epub ahead of print).

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