Mass Spectrometry Shared Instrumentation Laboratory
The BUSM Mass Spectrometry Resource operates two shared mass spectrometers to meet biomolecular mass spectral analysis needs of a group of NIH-funded investigators on the medical campus. These instruments were funded through the NIH/NCRR Shared Instrument (S10) program.
These instruments are:
- A Bruker Ultraflextreme TOF/TOF Mass Spectrometer
- A Thermo-Fisher Scientific hybrid LTQ-Orbitrap Mass Spectrometry system
- A Bruker Daltonics Solarix 12 Tesla Fourier Transform Mass Spectrometer
Here is information on how the instrument are operated.
- The instruments are used for ongoing collaborative projects involving post-translationally modified proteins, carbohydrates, or other glycoconjugates.
- These instruments are not used for routine proteomics service.
- Use of these instruments is through academic collaboration. Principal Investigators wishing to collaborate should contact Prof. Costello or Prof. Zaia. Typically a member of the collaborating lab works with a member of the Center for Biomedical Mass Spectrometry Staff. These people will work together to acquire and analyze the data.
For infomation on initiating a collaborating a contract, please contact Prof. Catherine E. Costello or Prof. Joseph Zaia.
Only samples representing no biological hazard may be analyzed using the shared instrumentation.
- All samples must be safe to manipulate on an open bench top.
- All samples must be non-radioactive.
- The Principal Investigator must certify that all samples represent no biological hazard and are not radioactive.