Recent Publications

The following list contains links to Recent Mass Spectrometry Resource Publications, including abstracts for the listed papers. Please contact Denise Neves to request a pdf file.

  • Burgoyne, J. R.; Haeussler, D. J.; Kumar, V.; Ji, Y.; Pimental, D. R.; Zee, R. S.; Costello, C. E.; Lin, C.; McComb, M. E.; Cohen, R. A.; Bachschmid, M. M. Oxidation of HRas cysteine thiols by metabolic stress prevents palmitoylation in vivo and contributes to endothelial cell apoptosis. FASEB J 2012, 26, 832-41. Pubmed Link

  • Wang, Q.; Shi, X.; Leymarie, N.; Madico, G.; Sharon, J.; Costello, C. E.; Zaia, J. A Typical Preparation of Francisella tularensisO-Antigen Yields a Mixture of Three Types of Saccharides. Biochemistry 2011, 50, 10941-50. Pubmed Link

  • Theberge, R.; Infusini, G.; Tong, W.; McComb, M. E.; Costello, C. E. Top-Down Analysis of Small Plasma Proteins Using an LTQ-Orbitrap. Potential for Mass Spectrometry-Based Clinical Assays for Transthyretin and Hemoglobin. Int J Mass Spectrom 2011, 300, 130-142. Pubmed Link

  • Szmola, R.; Bence, M.; Carpentieri, A.; Szabo, A.; Costello, C. E.; Samuelson, J.; Sahin-Toth, M. Chymotrypsin C is a co-activator of human pancreatic procarboxypeptidases A1 and A2. J Biol Chem 2011, 286, 1819-27. Pubmed Link

  • Staples, G. O.; Shi, X.; Zaia, J. Glycomics analysis of mammalian heparan sulfates modified by the human extracellular sulfatase HSulf2. PLoS ONE 2011, 6, e16689. Pubmed Link

  • Seward, R. J.; Drouin, E. E.; Steere, A. C.; Costello, C. E. Peptides Presented by HLA-DR Molecules in Synovia of Patients with Rheumatoid Arthritis or Antibiotic-Refractory Lyme Arthritis. Mol Cell Proteomics 2011, 10, M110 002477. Pubmed Link

  • Schumacher, V. A.; Schlotzer-Schrehardt, U.; Karumanchi, S. A.; Shi, X.; Zaia, J.; Jeruschke, S.; Zhang, D.; Pavenstaedt, H.; Drenckhan, A.; Amann, K.; Ng, C.; Hartwig, S.; Ng, K. H.; Ho, J.; Kreidberg, J. A.; Taglienti, M.; Royer-Pokora, B.; Ai, X. WT1-Dependent Sulfatase Expression Maintains the Normal Glomerular Filtration Barrier. J Am Soc Nephrol 2011, 22, 1286-96. Pubmed Link

  • Sargaeva, N. P.; Lin, C.; O’Connor, P. B. Differentiating N-terminal aspartic and isoaspartic Acid residues in peptides. Anal. Chem. 2011, 83, 6675-82. Pubmed Link

  • Sargaeva, N. P.; Lin, C.; O’Connor, P. B. Unusual fragmentation of beta-linked peptides by ExD tandem mass spectrometry. J Am Soc Mass Spectrom 2011, 22, 480-91. Pubmed Link

  • Naimy, H.; Buczek-Thomas, J. A.; Nugent, M. A.; Leymarie, N.; Zaia, J. Highly sulfated non reducing end-derived heparan sulfate domains bind fibroblast growth factor-2 with high affinity and are enriched in biologically active fractions. J Biol Chem 2011, 286, 19311-19319. Pubmed Link

  • Li, X.; Huang, Y.; O’Connor, P. B.; Lin, C. Structural heterogeneity of doubly-charged peptide b-ions. J Am Soc Mass Spectrom 2011, 22, 245-54. Pubmed Link

  • Leymarie, N.; McComb, M. E.; Naimy, H.; Staples, G. O.; Zaia, J. Differential characterization and classification of tissue specific glycosaminoglycans by tandem mass spectrometry and statistical methods. Int J Mass Spectrom 2011, 312, 144-154. Pubmed Link

  • Legrain, P.; Aebersold, R.; Archakov, A.; Bairoch, A.; Bala, K.; Beretta, L.; Bergeron, J.; Borchers, C. H.; Corthals, G. L.; Costello, C. E.; Deutsch, E. W.; Domon, B.; Hancock, W.; He, F.; Hochstrasser, D.; Marko-Varga, G.; Salekdeh, G. H.; Sechi, S.; Snyder, M.; Srivastava, S.; Uhlen, M.; Wu, C. H.; Yamamoto, T.; Paik, Y. K.; Omenn, G. S. The human proteome project: current state and future direction. Molecular & cellular proteomics : MCP 2011, 10, M111 009993. Pubmed Link

  • Langsdorf, A.; Schumacher, V.; Shi, X.; Tran, T.; Zaia, J.; Jain, S.; Taglienti, M.; Kreidberg, J. A.; Fine, A.; Ai, X. Expression regulation and function of heparan sulfate 6-O-endosulfatases in the spermatogonial stem cell niche. Glycobiology 2011, 21, 152-61. Pubmed Link

  • Huang, Y.; Shi, X.; Yu, X.; Leymarie, N.; Staples, G. O.; Yin, H.; Killeen, K.; Zaia, J. Improved LC-MS/MS of Heparan Sulfate Oligosaccharides via Chip-based Pulsed Make-up Flow. Anal. Chem. 2011, 83, 8222-8229. Pubmed Link

  • Han, L.; Costello, C. Electron Transfer Dissociation of Milk Oligosaccharides. J. Am. Soc. Mass Spectrom. 2011, 22, 997-1013. Pubmed Link

  • Dreyfuss, J. M.; Jacobs, C.; Gindin, Y.; Benson, G.; Staples, G. O.; Zaia, J. Targeted analysis of glycomics liquid chromatography/mass spectrometry data. Anal Bioanal Chem 2011, 399, 727-35. Pubmed Link

  • Crouch, E.; Nikolaidis, N.; McCormack, F.; McDonald, B.; Allen, K.; Rynkiewicz, M.; Cafarella, T.; White, M.; Lewnard, K.; Leymarie, N.; Zaia, J.; Seaton, B.; Hartshorn, K. Mutagenesis of SP-D informed by evolution and xray crystallography enhances defenses against Influenza A Virus in vivo. J Biol Chem 2011, 286, 40681-92. Pubmed Link

  • Bielik, A. M.; Zaia, J. Multistage Tandem Mass Spectrometry of Chondroitin Sulfate and Dermatan Sulfate. Int J Mass Spectrom 2011, 305, 131-137. Pubmed Link

  • Zee, R. S.; Yoo, C. B.; Pimentel, D. R.; Perlman, D. H.; Burgoyne, J. R.; Hou, X.; McComb, M. E.; Costello, C. E.; Cohen, R. A.; Bachschmid, M. M. Redox regulation of sirtuin-1 by S-glutathiolation. Antioxidants & redox signaling 2010, 13, 1023-32. Pubmed Link

  • Wada, Y.; Dell, A.; Haslam, S. M.; Tissot, B.; Canis, K.; Azadi, P.; Backstrom, M.; Costello, C. E.; Hansson, G. C.; Hiki, Y.; Ishihara, M.; Ito, H.; Kakehi, K.; Karlsson, N.; Kato, K.; Kawasaki, N.; Khoo, K. H.; Kobayashi, K.; Kolarich, D.; Kondo, A.; Lebrilla, C.; Nakano, M.; Narimatsu, H.; Novak, J.; Novotny, M. V.; Ohno, E.; Packer, N. H.; Renfrow, M. B.; Tajiri, M.; Thomsson, K. A.; Yagi, H.; Yu, S. Y.; Taniguchi, N. Comparison of Methods for Profiling O-glycosylation: HUPO Human Disease Glycomics/Proteome Initiative Multi-Institutional Study of IgA1. Mol Cell Proteomics 2010, 9, 719-727. Pubmed Link

  • Staples, G. O.; Shi, X.; Zaia, J. Extended NS domains reside at the non-reducing end of heparan sulfate chains. J Biol Chem 2010, 285, 18336-18343. Pubmed Link

  • Staples, G. O.; Naimy, H.; Yin, H.; Kileen, K.; Kraiczek, K.; Costello, C. E.; Zaia, J. Improved hydrophilic interaction chromatography LC/MS of heparinoids using a chip with postcolumn makeup flow. Anal. Chem. 2010, 82, 516-22. Pubmed Link

  • Ren, R.; Hong, Z.; Gong, H.; Laporte, K.; Skinner, M.; Seldin, D. C.; Costello, C. E.; Connors, L. H.; Trinkaus-Randall, V. Role of glycosaminoglycan sulfation in the formation of immunoglobulin light chain amyloid oligomers and fibrils. J Biol Chem 2010, 285, 37672-82. Pubmed Link

  • Palaima, E.; Leymarie, N.; Stroud, D.; Mizanur, R. M.; Hodgkin, J.; Gravato-Nobre, M. J.; Costello, C. E.; Cipollo, J. F. The Caenorhabditis elegans bus-2 mutant reveals a new class of O-glycans affecting bacterial resistance. J Biol Chem 2010, 285, 17662-72. Pubmed Link

  • Naimy, H.; Leymarie, N.; Zaia, J. Screening for anticoagulant heparan sulfate octasaccharides and fine structure characterization using tandem mass spectrometry. Biochemistry 2010, 49, 3743-3752. Pubmed Link

  • Li, X.; Lin, C.; O’Connor, P. B. Glutamine deamidation: differentiation of glutamic acid and gamma-glutamic acid in peptides by electron capture dissociation. Anal. Chem. 2010, 82, 3606-15. Pubmed Link

  • Li, X.; Lin, C.; Han, L.; Costello, C. E.; O’Connor, P. B. Charge remote fragmentation in electron capture and electron transfer dissociation. J Am Soc Mass Spectrom 2010, 21, 646-56. Pubmed Link

  • Ebbel, E. N.; Leymarie, N.; Schiavo, S.; Sharma, S.; Gevorkian, S.; Hersch, S.; Matson, W. R.; Costello, C. E. Identification of phenylbutyrate-generated metabolites in Huntington disease patients using parallel liquid chromatography/electrochemical array/mass spectrometry and off-line tandem mass spectrometry. Anal Biochem 2010, 399, 152-61. Pubmed Link

  • Chatterjee, A.; Carpentieri, A.; Ratner, D. M.; Bullitt, E.; Costello, C. E.; Robbins, P. W.; Samuelson, J. Giardia cyst wall protein 1 is a lectin that binds to curled fibrils of the GalNAc homopolymer. PLoS Pathog 2010, 6, e1001059. Pubmed Link

  • Carpentieri, A.; Ratner, D. M.; Ghosh, S. K.; Banerjee, S.; Bushkin, G. G.; Cui, J.; Lubrano, M.; Steffen, M.; Costello, C. E.; O’Keefe, B.; Robbins, P. W.; Samuelson, J. The antiretroviral lectin cyanovirin-N targets well-known and novel targets on the surface of Entamoeba histolytica trophozoites. Eukaryot Cell 2010, 9, 1661-8. Pubmed Link

  • Bowman, M. J.; Zaia, J. Comparative glycomics using a tetraplex stable-isotope coded tag. Anal. Chem. 2010, 82, 3023-31. Pubmed Link

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of BU School of Medicine