Selected Publications


 

1. Guha P, Morgan JW, Mostoslavsky G, Rodrigues NP, Boyd AS. Lack of Immune Response to Differentiated Cells Derived from Syngeneic Induced Pluripotent Stem Cells. Cell Stem Cell. 2013 Jan 22. doi:pii: S1934-5909(13)00009-X. 10.1016/j.stem.2013.01.006. [Epub ahead of print]

2. Sommer CA, Christodoulou C, Gianotti-Sommer A, Shen SS, Sailaja BS, Hezroni H, Spira A, Meshorer E, Kotton DN, Mostoslavsky G. Residual expression of reprogramming factors affects the transcriptional program and epigenetic signatures of induced pluripotent stem cells. PLoS One. 2012;7(12):e51711. doi: 10.1371/journal.pone.0051711. Epub 2012 Dec 14.

3. Gianotti-Sommer A, Rozelle SS, Sullivan S, Mills JA, Park SM, Smith BW, Iyer AM, French DL, Kotton DN, Gadue P, Murphy GJ, Mostoslavsky G. Generation of Human Induced Pluripotent Stem Cells from Peripheral Blood Using the STEMCCA Lentiviral  Vector. J Vis Exp. 2012 Oct 31;(68). doi:pii: 4327. 10.3791/4327.

4. Lafaille FG, Pessach IM, Zhang SY, Ciancanelli MJ, Herman M, Abhyankar A, Ying SW, Keros S, Goldstein PA, Mostoslavsky G, Ordovas-Montanes J, Jouanguy E, Plancoulaine S, Tu E, Elkabetz Y, Al-Muhsen S, Tardieu M, Schlaeger TM, Daley GQ, Abel L, Casanova JL, Studer L, Notarangelo LD. Impaired intrinsic immunity to HSV-1 in human iPSC-derived TLR3-deficient CNS cells. Nature. 2012 Oct 28. Doi: 10.1038/nature11583.

5. Farago, M., Rosenbluh, C., Tevlin, M., Fraenkel, S., Schlesinger, S., Masika, H., Gouzman, M., Teng, G., Schatz, D., Rais, Y., Hanna, J.H., Mildner, A., Jung, S., Mostoslavsky, G., Cedar, H., Bergman, Y. Clonal allelic predetermination of immunoglobulin-k rearrangement.Nature. 2012 Oct 25;490(7421):561-565. doi: 10.1038/nature11496. Epub 2012 Sep 30.

6. Mostoslavsky, G. The Magic Act of Generating Induced Pluripotent Stem Cells: Many Rabbits in the Hat. Stem Cells. 2012 Jan;30(1):28-32. Epub Sep 21 2011. doi: 10.1002/stem.742.

7. Christodoulou, C., Longmire, T.A., Shen, S.S., Bourdon, A., Sommer, C.A., Gadue, P., Spira, A., Gouon-Evans, V., Murphy, G.J., Mostoslavsky, G.*, and Kotton, D.N.* Mouse ES and iPS cells can form similar definitive endoderm despite differences in imprinted genes. Journal of Clinical Investigation. 2011 May 2. Pil:43853. Doi: 10.1172/JCI43853. Epub ahead of print. * Corresponding authors.

8. Koh, K.P., Yabuuchi, A., Rao, S., Huang, Y., Cunniff, K., Nardone, J., Laiho, A., Tahiliani, M., Sommer, C.A., Mostoslavsky, G., Laheesmaa, R., Orkin, S.H., Rodig, S.J., Daley, G.Q., and Rao, A. Tet1 and tet2 regulate 5-hydroxymethylcytosine production and cell lineage specification in mouse embryonic stem cells. Cell Stem Cell. 2011 Feb 4;8(2):200-213.

9. Ellis, J., Baum, C., Benvenisty, N., Mostoslavsky, G., Okano, H., Stanford, W.L., Porteus, M., Sadelain, M. Benefits of Utilizing Gene-Modified iPSCs for Clinical Applications. Cell Stem Cell. 2010 Oct 8;7(4):429-30.

10. Somers, A., Jean J.C., Sommer, C.A., Omari A., Ford, C.C., Mills, J.A., Ying, L., Gianotti Sommer, A., Jean, J.M., Smith, B.W., Lafyatis, R., Demierre, M.F., Weiss, D.J., French, D.L., Gadue, P., Murphy, G.J., Mostoslavsky, G., Kotton, D.N. Generation of transgene-free lung disease-specific human iPS cells using a single excisable lentiviral stem cell cassette. Stem Cells. 2010 Oct;28(10):1728-1740. Epub August 16 2010.

11. Staerk, J., Dawlaty, M.M., Gao, Q., Maetzel, D. Hanna, J., Sommer, C.A., Mostoslavsky, G. and Jaenisch, R. Reprogramming of human peripheral blood cells to induced pluripotent stem cells. 2010. Cell Stem Cell. Jul 2;7(1):20-24.

12. Sommer, C.A., Gianotti Sommer, A., Longmire, T.A., Christodoulou, C., Thomas, D.D., Gostissa, M., Alt, F.W., Murphy, G.J., Kotton, D.N., and Mostoslavsky, G. Excision of Reprogramming Transgenes Improves the Differentiation Potential of iPS Cells Generated with a Single Excisable Vector. 2010. Stem Cells. Jan;28(1):64-74. Epub Nov 10 2009.

13. Eminli, S., Foudi, A., Stadtfeld, M., Maherali, N., Ahfeldt, T., Mostoslavsky, G., Hock, H., and Hochedlinger, K. Differentiation stage determines potential of hematopoietic cells for reprogramming induced pluripotent stem cells. 2009. Nature Genetics. Sep;41(9):968-976. Epub 2009 August 9.

14. Sommer, C.A., Stadtfeld, M., Murphy, G.J., Hochedlinger, K., Kotton, D.N., and Mostoslavsky, G. iPS Cell Generation Using a Single Lentiviral Stem Cell Cassette. 2009. Stem Cells. Mar;27(3):543-549. Epub Dec 18 2008.

A full list of publications is available in PubMed.

Primary teaching affiliate
of BU School of Medicine