Control of fibroblastoid stromal networks by the immune system
Virus/Host interaction; viral domination of protein synthesis; antiviral compounds, systems biology of viral hemorrhagic fever, novel approaches to virus detection.
T cell disfunction and regulation in autoimmune disease
Control of respiratory syncytial virus RNA synthesis
Feng Feng, Ph.D.
Computational immunology; innate immunity; toll-like receptors and their transcriptional network
HIV immune evasion mechanisms
Cellular signals that regulate HIV transcription and replication
Reproductive immunology and the pathogenesis of gonococcal and chlamydia infections
Thomas B. Kepler, Ph.D.
Quantitative systems immunology; vaccine development
Acute lower respiratory tract infection; cytokines; innate immunity; neutrophil recruitment and activation; pneumonia; transcriptional and post-transcriptional regulation of gene expression
Stem cell biology and gene therapy
Host response to filovirus infection; molecular mechanisms of filovirus replication and transcription
Mechanisms responsible for the pathogenesis of systemic lupus erythematosus and lupus-associated atherosclerosis
Molecular biology of HIV-1; the role of virus-host cell interactions in pathogenesis
Vaccine development; microbial immunity and pathogenesis; effect of bacterial products on eukaryotic cells