Metabolomics Service Center

Metabolomics Service Center

Overview:

Metabolomics is the analysis of all metabolites in blood, tissue and organelles.  The Metabolomics Service Center at Boston Medical Center is an analytical facility specializing in mass spectrometry techniques, and offers a menu of analyses of known metabolites involved in carbohydrate, lipid, amino acid, energy and redox pathways.  Our goal is to provide investigators with the expertise and equipment to perform metabolite profiling that facilitates the analysis of major metabolic pathways in humans, animals and in vitro systems. The
Metabolomics Service Center primarily serves Boston University investigators, but will gladly accommodate requests from industry and non-BU investigators as well.

Service:

The mission of the Metabolomics Service Center is to perform assays and assist in the interpretation of the results. Following  assay modules have been developed for quantitative measurement of:

-   Plasma vitamin D metabolites (25(OH)2D3, 25(OH)D2 and 3epi-25(OH)D3)

-   Tryptophan metabolic pathway (tryptophan, kynurenine, kynurenic acid, anthralinic acid, xanthurenic acid, indoxyl sulfate and indoxyl acetate)

-    Plasma fatty acids.

-    Plasma amino acids

Other metabolite assay modules will be developed and validated in response to the emerging needs of Boston University investigators.

Instruments:

API 4000 Triple Quadrupole Mass Spectrometry,

Gas chromatography Mass Spectrometry

Agilent 1200 series LC systems

Location:

The Metabolomics Service center is located at 670 Albany St, 2nd floor.

 

Contacts

Director

Anqi Zhang, Ph.D.

617 414-2944

anqi@bu.edu