Joshua D. Safer, MD, FACP

Associate Professor of Medicine and Molecular Medicine

Education:

MD, University of Wisconsin – Madison

General field of research:

Endocrinology, Thyroid Disease

Affiliations other than medicine:

Evans Center for Interdisciplinary Biomedical Research

Department of Medicine Section of Endocrinology

Diabetes and Nutrition Section of Molecular Medicine

Contact information:

Office
M-1016
Phone: (617)-638 7470

Lab
M-1020
Phone: (617)-638 8530
Fax: (617)-638 8530

jsafer@bu.edu

Other research websites:

http://www.bumc.bu.edu/medicine/faculty/dabady/leung/safer/

www.bumc.edu/endo

Keywords:

Endocrinology; Thyroid; Androgens

Summary of research interest:

Manipulation of local thyroid hormone economy in order to treat cutaneous pathologies.

Recent publications:

Safer JD, Fraser LM, Ray S, Holick MF.  2001  Topically applied triiodothyronine stimulates epidermal proliferation, dermal thickening, and hair growth in mice and rats.  Thyroid 11(8):717-724.

Safer JD, Crawford TM, Fraser LM, Hoa M, Ray S, Chen TC, Persons K, Holick MF.  2003  Thyroid hormone action on skin:  diverging effects of topical versus intraperitoneal administration.  Thyroid 13(2):159-165.

Santini F, Ceccarini G, Montanelli L, Rosellini V, Mammoli C, Macchia P, Gatti G, Pucci E, Marsili A, Chopra IJ, Chiovato L, Vitto P, Safer JD, Braverman LE, Martino E, Pinchera A.  2003  Role for inner ring deiodination preventing transcutaneous passage of thyroxine.  Journal of Clinical Endocrinology and Metabolism 88(6):2825-2830.

Safer JD, Crawford TM, Holick MF.  2004  A role for thyroid hormone in wound healing through keratin gene expression.  Endocrinology  145(5):2357-2361.

Safer JD, Crawford TM, Holick MF.  2005  Topical thyroid hormone accelerates wound healing in mice.  Endocrinology  146(10):4425-4430.

Safer JD, Holick MF.  2008  Potential therapeutic uses of thyroid hormone,  Thyroid Disorders with Cutaneous Manifestations, Heymann WR, ed.,  Springer-Verlag, London, UK  181-186.

Safer JD, Persons K, Holick MF.  2009  A thyroid hormone deiodinase inhibitor can decrease cutaneous cell proliferation in vitro.  Thyroid  19(2):181-185.