The department’s rich research portfolio is made up of the clinical, basic and translational research conducted by faculty in each of our clinical and research sections.
American heart association tobacco regulatory science center (a-trac 2.0)
Emelia Benjamin
Winter 2018 center strategically focused atrial fibrillation research network
Emelia Benjamin
Jackson heart study coordinating center
Brooke Goodman
Role of serca2 c674 oxidation in mediating apoptosis in cardiac myocytes
Naomi Hamburg
Cardiovascular injury due to tobacco product use
Naomi Hamburg
Cardiovascular toxicity of tobacco products
Naomi Hamburg
Mitochondrial activity in fhs
Ivan Luptak
Preclinical research program
Shinobu Matsuura
The bone marrow extracellular matrix: scaffold of hematopoiesis
Kevin Monahan
Preempt hf – precision event monitoring for patients with heart failure using heartlogic
Karki Shakun
Fsp27 regulation of vascular function in human obesity
Frederick Ruberg
(Prenotification) scan-mp (screening fro cardiac amyloidosis with nuclear imaging in minority…
Frederick Ruberg
Cardiac amyloidosis fellowship
Flora Sam
Protocol efc15156:a randomized, double-blind, placebo-controlled, parallel-group, multicenter study to evaluate the effects of sotagliflozin on clinical outcomes in hemodynamically stable patients
Flora Sam
Mechanistic underpinnings of increased adipose tissue in hfpef
Assessing food intake with the automatic ingestion monitor
Caroline Apovian
Select – ex9536-4388 – semaglutide effects on cardiovascular outcomes in people with overweight…
Michael Holick
Pilot clinical trial to evaluate the pharmacokinetics of orally administered 25-hydroxyvitamin d3 and vitamin d3 in healthy adults and adults with a history of intestinal malabsorption
Devin Steenkamp
Switch pro: a randomised, cross-over, open-label, multi-centre trial comparing the effect of…
Devin Steenkamp
Myl-1601d-3001 a randomized, multicenter, open-label, parallel-group clinical study comparing the…
Nicole Spartano
Physical inactivity, epigenetic aging, and preclinical dementia
Utilizing a pluripotent stem cell model system to unravel the pathogenesis of pulmonary fibrosis
John Berk
An open-label, investigator study to evaluate the short-term (4 weeks) effects of tolcapone on transthyretin stability in subjects with leptomeningeal ttr amyloidosis (attr) with and without cns.
John Berk
Helios-a: a phase 3 study to evaluate the efficacy and safety of aln-ttrsc02 in patients with hattr amyloidosis
Ehab Billatos
Decamp 1 plus: prediction of lung cancer using noninvasive biomarkers
Markus Bosmann
New genetic models for c5a receptors
Markus Bosmann
Role reversal of mavs in bacterial sepsis
Alan Fine
Medical student summer research program in heart, lung and blood diseases
Finn Hawkins
Ipsc-derived airway basal cells to model human airway development and disease
Finn Hawkins
Generation of functional lung stem cells from human ipscs
Elizabeth Klings
A study evaluating the efficacy and safety of ralinepag to improve treatment outcomes in pah patients
Elizabeth Klings
Protocol apd811-303: a study evaluating the long-term efficacy and safety of ralinepag in subjects with pah via an open-label extension
Elizabeth Klings
Protocol ac-055-512 retro: a retrospective, multicenter chart review to collect dosing information of pah background medication in subject who participated in the ac-055-302 (seraphin) double-blind
Elizabeth Klings
A study evaluating the efficacy and safety of ralinepag to improve treatment outcomes in pah patients
Darrell Kotton
Characterization of ipsc-derived alveolar epithelial type ii cells
Darrell Kotton
A national ips cell network with deep phenotyping for translational research
Darrell Kotton
Thyroid follicular cell development in mouse and humans
Darrell Kotton
A new human ipsc in vitro system to model the inception of lung adenocarcinoma
Darrell Kotton
Derivation of lung epithelia from ips cells for advanced disease modeling
Darrell Kotton
Generation of functional lung stem cells from human ipscs
Paul Maglione
Role of b cell activating factor in non-infectious complications of common variable immunodeficiency
Paul Maglione
How b cell developmental defects shape manifestations of common variable immunodeficiency
Paul Maglione
Optimizing efficacy of interferon-y therapy in primary immunodeficiency patients
Paul Maglione
Immunomodulatory role of igg replacement therapy in common variable immunodeficiency
Joseph Mizgerd
Lung-resident antibacterial heterotypic immunity
George O’connor
Multi-omic approaches to mechanisms of vitamin d, environmental influences, and the microbiome on asthma
George O’connor
Inner city asthma consortium 3 (icac3)
George O’connor
Genetic and genomic characterization of the occurrence and progression of interstitial lung abnomarlities
George O’connor
Childrens respiratory and environmental workgroup (crew)
George O’connor
Childrens respiratory and environmental workgroup (crew)
George O’connor
Interstitial lung abnormalities: defining the phenotype, causes, and consequences
George O’connor
The new england precision medicine consortium of the all of us research program
Seppo Rinne
The impact of professional relationships on icu burnout
Jason Rock
Generation of functional lung stem cells from human ipscs
Targeting cardiovascular events to improve patient outcomes after sepsis
Andrew Wilson
Contribution of gain of function toxicity to aatd lung disease pathogenesis
Andrew Wilson
Base editing in patient-derived pluripotent stem cells for disease modeling and therapeutic development
Andrew Wilson
Thyroid hormone signaling in human hepatocytes
Andrew Wilson
Application of isogenic crispr-corrected patient ipscs to determine whether zaat-induced gain of function toxicity renders mz or zz lung epithelium susceptible to cigarette smoke injury
Rheumatology
Hans Dooms
Mechanisms underlying the role of interleukin-7 in type 1 diabetes
David Felson
Uncovering the genetic mechanisms behind joint-specific osteoarthritis
David Felson
Multicenter osteoarthritis study (most) second renewal-boston university
S.Reza Jafarzadeh
Effects of nsaids and non-nsaid analgesics on osteoarthritis outcomes
S.Reza Jafarzadeh
Global awards for advancing chronic pain research (advance) 2018 _ nsaids, cox2 inhibitors, and opioids long-term effects on knee osteoarthritis progression and joint replacement
S.Reza Jafarzadeh
Personalized dynamic regimens of physical activity for persons with knee osteoarthritis
Tuhina Neogi
Optimizing the value of pain management in knee osteoarthritis patients with comorbidities
Robert Simms
Dimethyl fumarate in systemic sclerosis-associated pulmonary arterial hypertension
Robert Simms
Protocol ml30172 – scleroderma lung study iii: combining of anti-fibrotic effects of pirfenidone with mycophenolate to treat scleroderma-related interstitial lung disease
Robert Simms
A phase 1 open-label study to determine the safety and tolerability of avid200, a transforming growth factor b (tgfb) inhibitor, in patients with diffuse cutaneous systemic
Robert Simms
A multicenter, randomized, double-blind, placebo-controlled phase 3 trial to evaluate efficacy and safety of lenabasum in dermatomyositis
Marcin Trojanowski
Protocol cpi-ife-004 a phase 2 randomized, double-blind, placebo-controlled study to assess the safety and efficacy of ifetroban in patients with diffuse cutaneous systemic sclerosis or systemic-scl
Marcin Trojanowski
A phase 2 multicenter, randomized, double-blind, placebo-controlled study to assess the safety and efficacy of ifetroban in patients with diffuse cutaneous systemic sclerosis
Vascular Biology
Rosa Breton
Contribution of mitochondrial-associated er membrane integrity to endothelial dysfunction in human diabetes mellitus
Jessica Fetterman
Relations of mitochondrial genetic variation and function with atrial fibrillation
Jingyan Han
Protein s-glutathionylation and vascular dysfunction with aging
Jingyan Han
Alcohol-induced dysregulation of thiol homeostasis and endothelial function