Ellen O Weinberg, PhD

Research Assistant Professor

Education:

PhD, Boston University Medical School

Post-doc, Beth Israel Deaconess Medical Center, Boston

General field of research:

Cardiovascular research

Contact information:

Office:
X-704  650 Albany Street

Phone: (617)-638 7677

Fax: (617)-638 8081

eweinbe@bu.edu

Keywords:

LV hypertrophy; heart failure; interleukins; inflammation; immunity; endothelium

Summary of research interest:

My research interest is the role of interleukin-1 receptor family members in inflammation and immunity in human diseases. My research has focused on ST2, an interleukin-1 receptor family member, and its ligand, IL-33 in cardiovascular disease.

Recent publications:

Weinberg EO, Shimpo M, De Keulenaer GW, MacGillivray C, Tominaga S, Solomon SD, Rouleau JL, Lee RT. 2002  Expression and regulation of ST2, an interleukin-1 receptor family member, in cardiomyocytes and myocardial infarction. Circulation; 106(23):2961-2966

Weinberg EO, Mirotsou M, Gannon J, Dzau VJ, Lee RT, Pratt RE. 2003  Sex and temporal dependence of the left ventricular genomic response to pressure overload. Physiol Genomics; 12(2):113-127

Weinberg EO, Shimpo M, Hurwitz, S, Tominaga S, Rouleau JL, Lee RT.  2003  Identification of serum soluble ST2 receptor as a novel heart failure biomarker. Circulation; 107(5):721-6

Mirotsou M, Dzau VJ, Pratt RE and Weinberg EO. 2006  Physiological genomics of cardiac disease: quantitative relationships between gene expression and left ventricular hypertrophy. Physiological Genomics; 27:86-94

Bartunek, J, Leen Delrue L, Van Durme F, Muller O, De Wiest, B, Croes R, Verstreken S, Goethals S, de Raedt H, Sarma J, Joseph L, Vanderheyden M, Weinberg EO. 2008  Non-myocardial production of ST2 protein in human hypertrophy and failure is related to diastolic load. J Am Coll Cardiol.; 52(25):2166-74.

Weinberg EO.  2009  ST2 protein in heart disease:  from discovery to mechanisms and prognostic value.  Biomarkers in Medicine; 3(5), xxx-xxx.  Review.