Antonio A. Lazzari, MD, FACR, CCD
MD – Escola Paulista Medicina – Brazil
Residence and Rheumatology Fellowship – University of S. Paulo
Laboratory Rheumatology Fellowship – Arthritis Section -BUSM.
General Internal Medicine Residence Boston VA HCS
General field of research:
Osteoporosis, Bone Metabolism, Body Composition, Clinical Densitometry
Affiliations other than medicine:
VA Boston HealthCare System – Primary Care and Radiology – Clinical Densitometry
Lecturer on Medicine – Harvard Medical School
VA Boston HCS
150 South Huntington Ave – Suite F2-10
Boston, MA 02130
Osteoporosis and Bone Metabolism Research. Director Male Osteoporosis Prevention and Treatment Clinic VA Boston HCS
Summary of research interest:
Dr. Lazzari’s research focuses on the evaluation, diagnosis, treatment and prevention of osteoporosis and osteoporotic fractures in men. He has performed and published studies of secondary causes of osteoporosis including: spinal cord injury patients, patients with epilepsy and chronic users of prednisone. Dr. Lazzari collaborates with other investigators of the VA Boston and other researchers from Spaulding Rehabilitation Hospital, developing bone densitometric techniques to assess bone health; bone loss and fat distribution in patients after spinal cord injury. He is also a local VA PI on a federal funded study which goal is to develop specific treatment and prevention guidelines for osteoporosis in SCI patients. He also collaborates with investigators of the Brigham and Women Hospital evaluating body composition by correlating bone mass/ lean and fat distribution in patients with congestive heart failure. Dr. Lazzari participated in a National Committee at VA Central Office to create clinical guidelines on diagnosing, treating and preventing osteoporosis and fractures for male patients. These VA guidelines have now been recommended and instituted nationally.
In addition to his research, Dr. Lazzari cares for both primary care and rheumatology patients, supervises residency clinics, attends in the inpatient general medical wards and mentors medical students from Boston University and Harvard Medical School, in addition to residents and fellows from BUMC, Beth Israel Deaconess Medical Center and Brigham and Women’s Hospital.
Lazzari AA, Dussault, P , Thakore-James, M and Bamford R.L.: Antiepileptic Drugs and Risk for Bone Loss in a Male Veteran Population; J.Clin. Dens. 2007;(10): 222-223.
Morse LR, Giangregorio L, Battaglino RA , Holland R, Craven BC, Stolzmann KL, Lazzari AA, Sabharwal S, Garshick E.: VA-Based Survey of Osteoporosis Management in Spinal Cord Injury. PM&R 2009; 1(3), 240-44.
Morse LR, Battaglino RA, Stolzmann KL, Hallett LD, Waddimba A, Gagnon D, Lazzari AA, Garshick E. Osteoporotic fractures and hospitalization risk in chronic spinal cord injury, Osteoporosis Internat 2009; 20:385-92.
Morse LR, Geller A, Battaglino RA, Stolzmann KL, Matthess K, Lazzari AA, Garshick E. Barriers to providing dual energy x-ray absorptiometry services to individuals with spinal cord injury. Am J Phys Med Rehabil. 2009; 88:57-60.
Morse LR, Lazzari AA, Battaglino R, Stolzmann KL, Matthess KR, Gagnon DR, Davis SA, Garshick E. Dual energy absorptiometry of the distal femur may be more reliable than the proximal tibia in spinal cord injury. Arch Phys Med Rehabil 2009; 90:827-31.
Travison TG, Basaria S, Store, TW et al: Clinical Meaningfulness of the Changes in Muscle Performance and Physical Function Associated With Testosterone Administration in Older Men With Mobility Limitation. J Gerontol A Biol Sci Med Sci (2011) first published online June 22, 2011 doi:10.1093.
Morse LR, Sudhakar S, Danilack V, Tun C, Lazzari A, Gagnon DR, Garshick E, Battaglino RA. Association between sclerostin and bone density in chronic spinal cord injury. J Bone Miner Res. (2012) Feb;27(2):352-9. PubMed PMID: 22006831; PubMed Central PMCID: PMC3288145.
Battaglino RA, Sudhakar S, Lazzari A, Garshick E, Zafonte R, Morse LR. Circulating sclerostin is elevated in short-term and reduced in long-term SCI. Bone. (2012) May 7. [Epub ahead of print] PubMed PMID: 22575440.
Zavin A, Daniels K, Arena R, Allsup K, Lazzari A, Joseph J, Schulze PC, Lecker SH, Forman DE. Adiposity facilitates increased strength capacity in heart failure patients with reduced ejection fraction. Int. J. Cardiol (2012) Jun 26. [Epub ahead of print] doi:10.2016/jijcard.2012.06.007 PMID:22743190.
Battaglino RA, Lazzari AA, Garshick E, Morse LR.: Spinal Cord Injury-Induced Osteoporosis: Pathogenesis and Emerging Therapies. Curr Osteoporos Rep (2012) 10:278–285 DOI 10.1007/s11914-012-0117-0.
Richards JS, Lazzari AA, Teves Qualler DA, Desale S, Howard R, Kerr GS. : Validation of the Osteoporosis Self-Assessment Tool in US Male Veterans. J Clin Densitom. 2013 Mar 12. pii: S1094-6950(13)00026-7. doi: 10.1016/j.jocd.2013.02.004. [Epub ahead of print]
Daniels KM, Zavin A, Allsup K, Joseph J, Arena R, Lazzari AA, Schulze PC, Lecker SH, Brown J, Forman DE.: Serum adiponectin in non-cachectic heart failure patients. Int J Cardiol. 2013 Jun 2. pii: S0167-5273(13)00987-X. doi: 10.1016/j.ijcard.2013.05.059. [Epub ahead of print]