Vasan Srini Ramachandran, MD, DM, FACC, FAHA

Professor of Medicine, Boston University School of Medicine

Chief, Section of Preventive Medicine & Epidemiologysrini_vasan3


India Institute of Medical Sciences, New Delhi, India, MBBS, MD, DM

General field of research:

Cardiology; Cardiovascular Epidemiology


Evans Center for Interdisciplinary Biomedical Research

Sections of Preventive Medicine and Epidemiology and Cardiology, Department of Medicine, Boston University School of Medicine.

Senior Investigator, The Framingham Heart study

Editor, Circulation Cardiovascular Genetics

Associate Editor, Circulation

Contact information:

801 Massachusetts Avenue, Suite 470, Boston, MA 02118

Phone: (617) 638-8090
Fax: (617) 638-8076

Other research websites:

Research group information

The Framingham Heart Study


Heart failure; Echocardiography; High blood pressure; Risk prediction

Summary of research interest:

I am a noninvasive cardiologist with specialization in cardiovascular epidemiology, and a senior investigator at the Framingham Heart Study. I am the co-director of the echocardiography and vascular testing laboratory at the Framingham Heart Study and I direct its fellowship training program. My epidemiological research has focused on 4 inter-related areas: a. the epidemiology of congestive heart failure, including identifying risk factors for the disease, characterizing the subgroups with diastolic heart failure, asymptomatic LV systolic and diastolic dysfunction, and evaluating the role of LV remodeling; b. population-based vascular testing and echocardiography, including identifying biological, environmental, and genetic determinants (correlates) of cardiac structure and function; normative standards; detailed assessment of biomarkers of the process of LV remodeling; c. epidemiology of high blood pressure, including characterizing the lifetime risk, rates of progression and risks associated with various degrees of elevation; and, d. exercise physiology, and exercise test responses in asymptomatic individuals and prognostic information; relations to endothelial function.

Recent publications:

Pencina MJ, D’Agostino RB Sr, Larson MG, Massaro JM, Vasan RS. 2009 Jun 8. Predicting the 30-Year Risk of Cardiovascular Disease. The Framingham Heart Study. Circulation.

PLieb W, Xanthakis V, Sullivan LM, Aragam J, Pencina MJ, Larson MG, Benjamin EJ, Vasan RS. 2009 Jun 8. Longitudinal Tracking of Left Ventricular Mass Over the Adult Life Course. Clinical Correlates of Short- and Long-Term Change in the Framingham Offspring Study. Circulation.

Böger RH, Sullivan LM, Schwedhelm E, Wang TJ, Maas R, Benjamin EJ, Schulze F, Xanthakis V, Benndorf RA, Vasan RS. 2009 Mar 31. Plasma asymmetric dimethylarginine and incidence of cardiovascular disease and death in the community. Circulation; 119(12):1592-600.

Schnabel RB, Sullivan LM, Levy D, Pencina MJ, Massaro JM, D’Agostino RB Sr, Newton-Cheh C, Yamamoto JF, Magnani JW, Tadros TM, Kannel WB, Wang TJ, Ellinor PT, Wolf PA, Vasan RS, Benjamin EJ. 2009 Feb 28. Development of a risk score for atrial fibrillation (Framingham Heart Study): a community-based cohort study. Lancet; 373(9665):739-45.

Lieb W, Safa R, Benjamin EJ, Xanthakis V, Yin X, Sullivan LM, Larson MG, Smith HM, Vita JA, Mitchell GF, Sawyer DB, Vasan RS. 2009 May. Vascular endothelial growth factor, its soluble receptor, and hepatocyte growth factor: clinical and genetic correlates and association with vascular function. Eur Heart J.; 30(9):1121-7.

Wang TJ, Pencina MJ, Booth SL, Jacques PF, Ingelsson E, Lanier K, Benjamin EJ, D’Agostino RB, Wolf M, Vasan RS. l. 2008. Vitamin D deficiency and risk of cardiovascular disease. Circulation; 117:503-511.

Parikh NI, Pencina MJ, Wang TJ, Benjamin EJ, Lanier KJ, Levy D, D’Agostino RB Sr, Kannel WB, Vasan RS. 2008.  A risk score for predicting near-term incidence of hypertension: the Framingham Heart Study.  Ann Intern Med; 148:102-110.

D’Agostino RB Sr, Vasan RS, Pencina MJ, Wolf PA, Cobain M, Massaro JM, Kannel WB. 2008. General cardiovascular risk profile for use in primary care: the Framingham Heart Study. Circulation; 117:743-753.