Course Descriptions
Medical NUTRITION GRADUATE PROGRAM
GMS NU 755 Molecular, biochemical and physiologic bases of nutrition I: energy balance and micronutrients (4 credits, Prerequisite: at least one semester each of Biochemistry and Physiology, or equivalent, and permission of the instructor) This is the first semester of a 2 semester sequence (that can be taken in either order) that focuses on the Physiological, Biochemical and Molecular Bases of Nutrition. This semester will cover concepts of essential nutrients and methods for determining their requirements (DRIs), body composition, nutrition and growth, energy expenditure, regulation of energy intake, vitamins and macro-mineral metabolism(Ca, P) and micronutrients. Functions and roles of micronutrients in signaling from gene to whole organism will be discussed. Implications for nutrient requirements through the lifecycle and in health and disease will be addressed. A discussion session will teach students to critically evaluate cutting-edge and seminal papers addressing each topic, and introduce students to state of the art research approaches and methodologies – basic (cell and molecular), clinical and epidemiological. Weekly writing assignments on the papers will provide experience and hone skills with scientific writing. S.K. Fried, 4cr, 1st sem.
GMS NU 756 Molecular, biochemical and physiologic bases of nutrition: Macronutrients (4 credits, Prerequisite: at least one semester each of Biochemistry and Physiology and permission of the instructor, Fried.) Regulation of lipid, carbohydrate, and protein digestion, absorption, transport, tissue and cellular metabolism. Integration of macronutrient metabolism in response to alteration in nutritional status (e.g. starvation, obesity) on a whole body and tissue-specific basis. Mechanism regulating macronutrient metabolism in response to stresses such as exercise and aging and disease. A discussion session will teach students to critically evaluate research papers, provide knowledge of seminal papers in the field, and introduce students to research approaches and state of the art methods (e.g. assessment of metabolic flux using stable isotopes, euglycemic clamps, metabolomics). S.K. Fried, 4 cr, 2nd sem.
GMS NU 620 Research, Clinical and Public Policy Applications in Medical Nutrition Sciences (Prereq: Human Physiology, or equivalent, consent of instructor. Prereq or Coreq NU 755 or 756). The course will focus on disease states related to nutrition and diet, with a major focus on clinical nutrition research. It will: 1. Acquaint students with current concepts and methods in clinical nutrition research, familiarize students with clinical research and how investigators approach nutrition-related questions in their specific fields to answer questions related to disease states, 3. Evaluate the role of nutrition as it relates to development, prevention and therapy of18major diseases, including cardiovascular, diabetes, gastrointestinal, osteoporosis, obesity, and cancer. Apovian. 4 cr, 2nd sem.
GMS NU 700 Medical Nutrition Sciences Seminar Students develop and present a research seminar. S. Fried and L. Moore 2 cr, Fall
GMS NU 804 Directed Studies in Medical Nutrition TBA. Directed studies of a specific advanced topic with a faculty member.
GMS NU 901, 902 Research in Medical Nutrition Sciences TBA. var cr, 1st and 2nd sem.

