Major Accomplishments

September 2013

Dr. Mark Sloan received 2013 Robert Dawson Evans Quality Improvement Award in recognition to his work in Quality Improvement and Patient Safety.

February 2013

Dr. Naomi Ko’s work with the NCI-funded patient navigation research program at BMC was featured in the Feb 15 ASCO Post.

http://www.ascopost.com/issues/february-15,-2013/a-look-at-the-patient-navigator-program-in-breast-cancer.aspx

Dr. Dominguez was promoted to assistant professor and selected as a member of the Evo-Devo-Eco Network (EDEN) exchange selection committee, a NSF Research Coordination Network

Dr. Omar Eton will serve as Treasurer for the Massachusetts Society of Clinical Oncologists (MSCO).

January 2009: “Reaccreditation with Commendation of the Cancer Programs by the American College of Surgeons.” www.acosog.org

Click to view the section of Hematology and Medical Oncology 2009 Annual Report

PUBLICATIONS

David H.K. Chui, MD, FRCPC

Chui DHK, Fucharoen S, Chan V. Hemoglobin H disease: not necessarily a benign disorder. Blood 2003; 101:791-800.

Ding C, Chiu RWK, Lau TK, Leung TN, Chan LC, Chan AYY, Charoenkwan P, Ng ISL, Law H-Y, Ma ESK, Xu X, Wanapirak C, Sanguansermsri T, Liao C, Ai MATJ, Chui DHK, Cantor CR, Lo YMD. MS analysis of single-nucleotide differences in circulating nucleic acids: Application to noninvasive prenatal diagnosis. Proc Natl Acad Sci USA 2004; 101:10762-10767.

Luo H-Y, Adewoye AH, Eung SH, Skelton TP, Quillen K, McMahon L, Steinberg MH, Chui DHK. A novel sickle hemoglobin: Hemoglobin S – South End. J Pediatr Hematol Oncol 2004; 26:773-776..

Luo H-Y, Tang W, Eung SH, Coad, JE, Canfield P, Keller F, Crowell Jr EH, Steinberg MH, Chui DHK. Dominantly inherited beta-thalassemia intermedia due to a new single nucleotide deletion in exon 2 of the beta-globin gene: Hb Morgantown (beta91 CTG>CG). J Clin Pathol 2005; 58:1110-1112.

Chui DHK, Cunningham MJ, Luo H-Y, Wolfe LC, Neufeld EJ, Steinberg, MH. Screening and counseling for thalassemia. Blood 2006; 107:1735-1737.

Masiello D, Heeney MM, Adewoye AH, Eung SH, Luo H-Y, Steinberg MH, Chui DHK. Hemoglobin SE disease – A concise review. Am J Hematol 2007; 82:643-649.

Chui DHK. Thal for Thal. Blood 2007; 110:2788-2789.

Gibney GT, Panhuysen CIM, So JCC, Ma ESK, Ha SY, Li CK, Lee ACW, Li CK, Yuen HL, Lau YL, Johnson DM, Farrell JJ, Bisbee AB, Farrer LA, Steinberg MH, Chan LC, Chui DHK. Variation and heritability of Hb F and F-cells among beta-thalassemia heterozygotes in Hong Kong. Am J Hematol 2008; 83:458-464.

Chen ZY, Luo H-Y, Basran RK, Hsu T-H, Mang DWH, Nuntakarn L, Rosenfield CG, Patrinos GP, Hardison RC, Steinberg MH, Chui DHK. A T>G transversion at NT 567 upstream of HBG2 in a GATA-1 binding motif is associated with elevated Hb F. Mol Cell Biol 2008; 28:4386-4393.

Sedgewick AE, Timofeev N, Sebastiani P, So JCC, Ma ESK, Chan LC, Fucharoen G, Fucharoen S, Barbosa CG, Vardarajan BN, Farrer LA, Baldwin CT, Steinberg MH, Chui DHK. BCL11A is a major HbF quantitative trait locus in three different populations with beta-hemoglobinopathies. Blood Cells Mol Dis 2008; 41:255-258.

Wilcox I, Boettger K, Greene L, Malek A, Davis L, Steinberg MH, Luo H-Y, Chui DHK. Hemoglobin Kenya composed of alpha- and (Agamma beta)-fusion-globin chains, associated with hereditary persistence of fetal hemoglobin. Am J Hematol 2009; 84:55-58.

Chen ZY, Luo H-Y, Steinberg MH, Chui DHK. BCL11A represses HBG transcription in K562 cells. Blood Cells Mol Dis 2009; 42:144-149.

Koenig SC, Becirevic E, Hellberg MSC, Li MY, So JCC, Hankins JS, Ware RE, McMahon L, Steinberg MH, Luo H-Y, Chui DHK. Sickle cell disease caused by heterozygosity for Hb S and novel LCR deletion: Report of two patients. Am J Hematol 2009; 84:603-606.

Isabel Dominguez, PhD

Wu H, Symes K, Seldin DC, Dominguez I. Threonine 393 of β-catenin regulates interaction with Axin. J. Cell. Biochem. 2009 (in press)

Dominguez I, Sonenshein, GE, Seldin DC. CK2 as a regulator of Wnt and NFkB signaling in embryonic development and cancer. Cell Mol Life Sci 2009 (in press)

Bryja V, Schambony A, Čajánek L, Dominguez I, Arenas E, Schulte G. β-arrestin and casein kinase 1/2 define distinct branches of non-canonical WNT signaling pathways. EMBO Rep. 2008; 9(12):1244-50

Chitalia VC, Foy RL, Bachschmid MM, Zeng L, Panchenko MV, Zhou MI, Bharti A, Seldin DC, Lecker SH, Dominguez I, Cohen HT. Jade-1 inhibits Wnt signaling by ubiquitinating beta-catenin and mediates Wnt pathway inhibition by pVHL, Nat Cell Biol. 2008; 10(10):1208-16

Seldin DC , Lou DY, Toselli P, Landesman-Bollag E, Dominguez I. Gene targeting of CK2 catalytic subunits. Mol Cell Biochem. 2008; 316 (1-2):141-7

Lou DY, Dominguez I, Toselli P, Landesman-Bollag E, O’Brien C, Seldin DC. The alpha catalytic subunit of protein kinase CK2 is required for normal embryonic development Mol. Cell Biol. 2008; 28(1):131-9

Currier N, Solomon SE, Demicco EG, Chang DL, Farago M, Ying H, Dominguez I, Sonenshein GE, Cardiff RD, Xiao ZX, Sherr DH, Seldin DC. Oncogenic signaling pathways activated in DMBA-induced mouse mammary tumors Toxicologic Pathology 2005; 33(6):726-37

Dominguez I, Mizuno J, Wu H, Imbrie GA, Symes K, Seldin DC. A role for CK2a/b in Xenopus early embryonic development, Mol Cell Biochem 2005; 274(1-2):125-31

Farago M, Dominguez I, Landesman-Bollag E, Xu X, Rosner A, Cardiff RD, Seldin DC. Kinase inactive GSK3b promotes Wnt signaling and mammary tumorigenesis. Cancer Research 2005; 65(13):5792-801

Seldin DC, Landesman-Bollag E, Farago M, Currier N, Lou D, Dominguez I. CK2 as a positive regulator of Wnt signaling and tumorigenesis. Mol Cell Biochem. 2005; 274(1-2):63-7

Green JB, Dominguez I, Davidson LA. Self-organization of vertebrate mesoderm based on simple boundary conditions. Dev Dyn 2004; 231(3):576-81

Dominguez I, Mizuno J, Wu H, Song DH, Symes K, Seldin DC. Protein kinase CK2 is required for dorsal axis formation in Xenopus embryos. Dev Biol 2004; 274(1):110-24

Song DH, Dominguez I, Mizuno J, Kaut M, Mohr SC, Seldin DC. CK2 Phosphorylation of the armadillo repeat region of b-catenin potenciates Wnt signaling J Biol Chem 2003; 278(26):24018-25

Dominguez I, Green JB. Missing links in GSK3 regulation. Dev Biol 2001; 235(2):303-13

Dominguez I, Green JB. Dorsal downregulation of GSK3b by a non-Wnt-like mechanism is an early molecular consequence of cortical rotation in early Xenopus embryos. Development 2000; 127(4):861-8

Dominguez I, Itoh K, Sokol SY. Role of glycogen synthase kinase-3b as a negative regulator of dorsoventral axis formation in Xenopus embryos. Proc Natl Acad Sci USA 1995; 92(18):8498-502

Kevan L. Hartshorn, MD

Mogues T, Etzerodt M, Hall C, Engelich G, Graverson J, and Hartshorn KL. Tetranectin binds to the kringle 1-4 form of angiostatin and modifies its functional activity. Journal of Biomedicine and Biotechnology.2004; 2:73-78.

Van Eijk M, White MR, Batenburg JJ, Vaandrager AB, van Golde LMG, Haagsman HP, and Hartshorn KL. Interactions of influenza A virus with sialic acids present on porcine surfactant protein D. American Journal of Respiratory Cell Molecular Biology. 2004;30:871-9.

Leth-Larsen R, Garred P, Jensenius H, Meschi J, Hartshorn KL, Tornoe I, Madsen J, Madsen HO, Sorensen G, Crouch E, and Holmskov U. A common polymorphism in the SFTPD gene influences assembly, function, and concentration of surfactant protein D. J Immunol. 2005;174: 1532-1538.

Tacken P, Hartshorn KL, White MR, van Kooten C, van de Winkel JGJ, Reid KBM, Batenburg JJ. Effective targeting of pathogens of neutrophils via chimeric surfactant protein D/anti-CD89 protein. J. Immunol. 2004; 172: 4934-4940.

White MR, Crouch EC, van Eijk M, Elliott J, Hartshorn MW, Pemberton L, Ligtenberg T, Holmskov U, Hartshorn KL. Cooperative anti-influenza activities of respiratory innate immune proteins and neuraminidase inhibitor. Amer. J Physiol. 2004;288:831-840.

Crouch E, Tu Y, Briner D, McDonald B, Smith K, Holmskov U, Hartshorn K. Ligand binding of human surfactant protein D: Expression of a mutant trimeric collectin that shows enhanced interactions with influenza a virus. J Biol Chem. 2005 Feb 11; [Epub ahead of print]

Carol L. Rosenberg, MD

Schlechter BL, Yang Q, Larson PS, Golubeva A, Blanchard RA, de las Morenas A, Rosenberg CL. Quantitative DNA fingerprinting may distinguish new primary breast cancers from disease recurrence. J Clin Oncol 2004; 22:1830-1838.

King C, Guo N, Frampton GM, Gerry NP, Lenburg ME, Rosenberg CL. Reliability and reproducibility of high-density oligonucleotide arrays using independently isolated and amplified small-sample RNA from in vivo tissue. J Molec Diagnostics 2005; 7:57-64.

Larson PS, Schlechter BL, de las Morenas A, Cupples LA, Garber JE, Rosenberg CL. Allele imbalance, or loss of heterozygosity, in normal-appearing breast epithelium of sporadic cancer cases and BRCA1 gene mutation carriers is increased compared with reduction mammoplasty tissues. J Clin Oncol 2005; 23:8613-8619.

Larson PS, de las Morenas A, Cerda SR, Bennett SR, Cupples LA, Rosenberg CL. Quantitative analysis of allele imbalance supports atypical ductal hyperplasia lesions as direct breast cancer precursors. J Pathol 2006; 209:306-317. [Epub ahead of print 2006 Apr 7 DOI 10.1002/cncr.22223].

Larson PS, Ungarelli R, de las Morenas A, Cupples LA, Rowlings K, Palmer JR, Rosenberg CL. In utero exposure to diethylstilbestrol (DES) does not increase genomic instability in normal or neoplastic breast tissue. Cancer 2006; 107:2122-6. [Epub ahead of print 2006 Sep 22 DOI 10.1002/cncr.22223].

Tripathi A, King CL, de las Morenas A, Antoine G, Hirsch E, Kavanah M, Mendez J, Stone MD, Gerry NP, Lenburg M, Rosenberg CL. Gene expression abnormalities in histologically normal epithelium of breast cancer patients. MS submitted.

Murabito JM, Rosenberg CL, Finger D, Kreger B, Larson MG, Splansky GL, Antman KH, Hwang S-J. A genome-wide association study of breast and prostate cancer in the NHLBI’s Framingham Heart Study. MS submitted.

Vaishali Sanchorawala, MD

Sanchorawala V, Wright DG, Seldin DC, Falk RH, Finn KT, Dember LM, Berk JL, Quillen K, Anderson JJ, Comenzo RL, Skinner M. High-dose intravenous melphalan and autologous stem cell transplantation as initial therapy or following two cycles of oral chemotherapy for the treatment of AL amyloidosis: results of a prospective randomized trial. Bone Marrow Transplantation 2004; 33 (4): 381-388.

Skinner M, Sanchorawala V, Seldin DC, Dember LM, Falk RH, Berk JL, Anderson JJ, O’Hara C, Finn KT, Libbey CA, Wiesman J, Quillen K, Swan N, Wright DG. High-dose melphalan and autologous stem cell transplantation in patients with AL amyloidosis: An 8-year study. Ann Intern Med 2004; 140: 85-93.

Seldin DC, Anderson JJ, Sanchorawala V, Malek K, Wright DG, Quillen K, Finn KT, Berk JL, Dember LM, Falk RH, Skinner M. Improvement in quality of life of patients with AL amyloidosis treated with high-dose melphalan and autologous stem cell transplantation. Blood 2004; 104:1888-1893.

Oran B, Malek KM, Sanchorawala V, Wright DG, Quillen K, Finn KT, LaValley M, Skinner M, Seldin DC. Predictive factors for hematopoietic engraftment after autologous peripheral blood stem cell transplantation for AL amyloidosis. Bone Marrow Transplantation 2005; 35: 567-575.

Gertz MA, Comenzo R, Falk RH, Fermand JP, Hazenberg BP, Hawkins PN, Merlini G, Moreau P, Ronco P, Sanchorawala V, Sezer O, Solomon A, Grateau G. Definition of Organ Involvement and Treatment Response in Primary Systemic Amyloidosis (AL): A Consensus Opinion From the 10th International Symposium on Amyloid and Amyloidosis. American Journal of Hematology 2005 (in press)

Berk JL, Weisman JF, Skinner M, Sanchorawala V. Diaphragm paralysis in primary systemic amyloidosis. Amyloid, Journal of Protein Folding Disorders 2005 (in press)

Berk JL, Weisman JF, Skinner M, Sanchorawala V. Diaphragm paralysis in primary systemic amyloidosis. Amyloid, Journal of Protein Folding Disorders 2005 (in press)

David Seldin, MD, PhD

Landesman-Bollag, E., R. Romieu-Mourez, D. H. Song, G. E. Sonenshein, R. D. Cardiff and D. C. Seldin Protein kinase CK2 in mammary gland tumorigenesis. Oncogene, 2001 20(25): 3247-57.

Song DH, Dominguez I, Mizuno J, Kaut M, Mohr SC, Seldin DC. CK2 phosphorylation of the armadillo repeat region of β-catenin potentiates Wnt signaling, J Biol Chem, 2003; 278:24018-25.

Dominguez I, Mizuno J, Wu H, Song D, Symes K, and Seldin DC. Protein kinase CK2 Is required for dorsal axis formation In Xenopus embryos, Developmental Biology, 2004; 274:110-24.

Farago M, Dominguez I, Landesman-Bollag E, Xu X, Patel S, Rosner A, Cardiff RD, Seldin DC. Kinase-inactive glycogen synthase kinase 3β promotes Wnt signaling and mammary tumorigenesis, Cancer Research, 2005; 65: 5792-5801.

Currier N, Solomon SE, Demicco EG, Chang DLF , Farago M, Ying H, Dominguez I, Sonenshein GE, Cardiff RD, Xiao ZJ, Sherr DH, Seldin DC. Oncogenic signaling pathways activated in DMBA-induced mouse mammary tumors, Toxicol. Pathol., 2005; 33:726-737.

Sanchorawala V, Skinner M, Quillen K, Finn KT, Doros G, Seldin DC. Long-term outcome of patients with AL amyloidosis treated with high-dose melphalan and stem cell transplantation, Blood 110(10):3561-3.

Connors LH, Jiang Y, Budnik M, Théberge R, Prokaeva T, Bodi KL, Seldin DC, Costello CE, Skinner M. Heterogeneity in Primary Structure, Post-Translational Modifications, and Germline Gene Usage of Nine Full-Length Amyloidogenic kappa1 Immunoglobulin Light Chains. Biochemistry. 2007 Dec 11;46(49):14259-71.

Belguise K, Guo S, Yang S, Rogers AE, Seldin DC, Sherr DH, and Sonenshein GE. Green Tea Polyphenols Reverse Cooperation between c-Rel and CK2 that Induces the Aryl Hydrocarbon Receptor, Slug and an Invasive Phenotype, Cancer Research 2007 67(24):11742-5.

Lou DY, Dominguez I, Toselli P, Landesman-Bollag E, O’Brien C, and Seldin DC. The Alpha Catalytic Subunit of Protein Kinase CK2 Is Required For Mouse Embryonic Development, Mol Cell Biol. 2008, 28(1):131-9.

Lavatelli F, Perlman DH, Spencer B, Prokaeva T, McComb ME, Théberge R, Connors LH, Bellotti V, Seldin DC, Merlini G, Skinner M, Costello CE. Amyloidogenic and associated proteins in systemic amyloidosis proteome of adipose tissue. Mol Cell Proteomics. 2008 Aug;7(8):1570-83.

Seldin DC, Lou DY, Toselli P, Landesman-Bollag E, Dominguez I. Gene targeting of CK2 catalytic subunits. Mol Cell Biochem. 316 (1-2):141-7.

Chitalia VC, Foy RL, Bachschmid MM, Zeng L, Panchenko MV, Zhou MI, Bharti A, Seldin DC, Lecker SH, Dominguez I, Cohen HT. Jade-1 inhibits Wnt signalling by ubiquitylating beta-catenin and mediates Wnt pathway inhibition by pVHL. Nat Cell Biol. 2008, 10 (10):1208-16.

Martin H. Steinberg, MD

Sebastiani, P., Wang, L., Nolan, V.G., Baldwin, C.T., Ma, Q., Steinberg, M.H. Fetal hemoglobin in sickle cell anemia: Bayesian modeling of genetic associations. Am. J. Hematol. 83: 189, 2008.

Morris, C.R., Suh, J.H., Larkin, S., Bland, D.A., Steinberg, M.H., Vichinsky, E.P., Shigenaga, M., Ames, B., Kuypers, F.A., Klings, E.S. Erythrocyte glutamine depletion, altered redox environment, and pulmonary hypertension in sickle cell disease. Blood 111: 402, 2008.

Sebastiani, P., Zhao, Z., Abad-Grau, M, Riva, A., Hartley, S., Sedgewick, A., Doria, A., Montano, M., Melista, E., Terry, D., Perls, T.T., Steinberg, M.H., Baldwin, C.T. A hierarchical and modular approach to the discovery of robust associations in genome-wide association studies from pooled DNA samples. BMC Genet.ePub Jan 14, 2008.

Klings, E.S., Bland, A., Rosenman, D., Princeton, S., Odhiambo, A., Li, G., Bernard, S.A., Steinberg, M.H., Farber, H.W. Pulmonary arterial hypertension and left-sided heart disease in sickle cell disease: clinical characteristics and association with soluble adhesion molecule expression Am. J.Hematol. 83: 547, 2008.

Taylor, J.G., IV, Nolan, V.G., Mendelsohn, L., Kato, G J., Gladwin, M.T., Steinberg, M.H. Chronic hyper-hemolysis in sickle cell anemia: association of vascular complications and mortality with less frequent vasoocclusive pain. PLoS One May 7;3(5):e2095, 2008.

Gibney, G.T., Panhuysen, C.I.M., So, J.C.C., Ma, E.S.K., Ha, S.Y., Li, C.K., Lee, A.C.W., Li, C.K., Yuen, H.L., Lau, Y.L., Johnson, D., Farrell, J.J., Bisbee, A., Farrer, J.J., Steinberg, M.H., Chan, L.C., Chui, D.H.K. Variation and heritability of Hb F and F-cells among β-thalassemia heterozygotes in Hong Kong. Am. J. Hematol. 83: 458, 2008.

Chen,Z., Hong-yuan, L,. Basran, R.K., Rosenfield, C.G., Patrinos, G.P., Hardison, R.C., Steinberg, M.H., Chui, D.H.K. A T-to-G transversion at nucleotide -567 upstream of HBG2 in a GATA-1 binding motif is associated with elevated hemoglobin F. Mol. Cell. Biol. 28: 4386, 2008.

Sedgewick, A.E., Timofeev, N., Sebastiani, P., So, J.C.C., Ma, E.S.K., Chan, L.C., Fucharoen, G., Fucharoen, S., Barbosa, C.G., Vardarajan, B., Farrer, L.A., Baldwin, C.T., Steinberg, M.H., Chui, D.H.K. BCL11A is a major HbF quantitative trait locus in three different populations with β-hemoglobinopathies. Blood Cells, Mol. and Dis. 41: 255, 2008. http://dx.doi.org/10.1016/j.bcmd.2008.06.007

Nolan, V.G., Zhang, Y., Lash, T., Sebastiani, P., Steinberg, M.H. Association of wind speed and the occurrence of sickle cell acute painful episodes: Results of a case-crossover study. Br. J. Haematol. 143: 433, 2008.

Zhao, Z., Timofeev, N., Hartley, S., Chui, D.H.K., Fuchareon, Perls, T.T, Steinberg, M.H. Baldwin, C.T., Sebastiani, P. Imputation of missing genotypes: an empirical evaluation of IMPUTE. BMC Genetics (in press).

Lewis Weintraub, MD

Weintraub, L.R., Scola, M.,: Hematology and Immunology. IN: Appleton & Lange USMLE STEP 1 Outline Review, Goldberg, J.S., chapter 5: 123 186, 2004

Tiwari, S., Dong, H., Kim, E. J., Weintraub, L.R., Epstein, P. M., Lerner, A.: Type 4 cAMP Phosphodiesterase (PDE4) Inhibitors Augment Glucocorticoid-mediated Aptosis in B cell Chronic Lymphocytic Leukemia (B-CLL) in the Absence of Exogenous Adenylyl Cyclase Stimulation. Biochemical Pharmacology 2005; 69:473-483.

Xuemei Zhong, PhD

Zhong, X., T. J. Schneider, et al. (2001). An alternatively spliced long form of Fas apoptosis inhibitory molecule (FAIM) with tissue-specific expression in the brain. Mol Immunol 38: 65-72.

Irigoyen, I.M., T. Mizuno, X. Zhong, et al. (2002). B cell activation leads to upregulated expression of the murine Sik-similar protein gene. Mol Immunol.38:861-866

Zhong, X., T. Mizuno, and T. L. Rothstein. (2003). Fas-induced apoptosis in B cells. Apoptosis 8:451.

Zhong, X., C. Bai, W. Gao, T. B. Strom, and T. L. Rothstein. (2004). Featured Article of the Month: Suppression of expression and function of negative immune regulator PD-1 by certain pattern recognition and cytokine receptor signals associated with immune system danger. Int Immunol 16:1181.

Barrington, R. A., X. Zhong, M. Zhang, H. Jonsson, N. Holodick, A. Cherukuri, S. K. Pierce, T. L. Rothstein, and M. C. Carroll. (2005). CD21/CD19 coreceptor signaling promotes B cell survival during primary immune responses. J Immunol 175:2859.

Kandel R, Hartshorn KL. Novel strategies for prevention and treatment of influenza. Expert Opinion, 9:1-22, 2005.

Tecle T, White MR, Hartshorn KL. Innate Immunity to Influenza Virus Infection. Current Respiratory Reviews. 2005

Seldin DC . Interfering with Amyloidosis. Blood 2004,104 (12), 3419-3420.

BOOK CHAPTERS

Chui DHK, Steinberg MH. Laboratory diagnosis of hemoglobinopathies and thalassemias. In: Hematology: Basic Principles and Practice, 5th edition. Hoffman R, Benz Jr EJ, Shattil SJ, Furie B, Silberstein LE, McGlave P, Heslop HE. (eds.) Elsevier, Philadelphia, 2009; 525-533.

Martin H Steinberg, Edward J Benz Jr, Adeboye H Adewoye and Benjamin Ebert. Pathobiology of the Human Erythrocyte and its Hemoglobin. Hematology Basic Principles and Practice 4 th Edition 2005. Edited by Ronald Hoffman, Edward J Benz Jnr, Sanford J Shattil, Bruce Furie, Harvey J Cohen, Leslie E Silberstein, Philip McGlave. Elsevier Churchill Livingstone.

Adeboye Adewoye ., Martin H Steinberg. Pregnancy in hemoglobinopathies (Cambridge University Press 2005 in press).

Seldin DC and Skinner M. Amyloidosis. In: Lichtenstein LM, Busse WW, and Geha RS, ed. Current Therapy in Allergy, Immunology, and Rheumatology, Phila.: Mosby, 2004, 260-7.

Seldin DC and Skinner M. Amyloidosis. In: ED Harris, S Ruddy, CB Sledge, JS Sergent, and RC Budd, ed. Kelley’s Textbook of Rheumatology 7th edition,. Elsevier, Philadelphia, 2005, 1697-1704.

Steinberg, M.H., Farber, H.W. Hospital Medicine, 2nd ed. Chapter Sickle Cell Disease 2005

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of BU School of Medicine