2017 Publications


RNA elongation by respiratory syncytial virus polymerase is calibrated by conserved region V. Braun MR, Deflubé LR, Noton SL, Mawhorter ME, Tremaglio CZ, Fearns R. PLoS Pathog. 2017 Dec 27;13(12):e1006803. doi: 10.1371/journal.ppat.1006803. [Epub ahead of print]

Reducing the RNA binding protein TIA1 protects against tau-mediated neurodegeneration in vivo. Apicco DJ, Ash PEA, Maziuk B, LeBlang C, Medalla M, Al Abdullatif A, Ferragud A, Botelho E, Ballance HI, Dhawan U, Boudeau S, Cruz AL, Kashy D, Wong A, Goldberg LR, Yazdani N, Zhang C, Ung CY, Tripodis Y, Kanaan NM, Ikezu T, Cottone P, Leszyk J, Li H, Luebke J, Bryant CD, Wolozin B. Nat Neurosci. 2018 Jan;21(1):72-80. doi: 10.1038/s41593-017-0022-z. Epub 2017 Nov 20.

Increased expression and modulated regulatory activity of co-inhibitory receptors PD-1, TIGIT and TIM-3 in lymphocytes of systemic sclerosis patients. Fleury M, Belkina AC, Proctor EA, Zammitti C, Simms RW, Lauffenburger DA, Snyder-Cappione JE, Lafyatis R, Dooms H. Arthritis Rheumatol. 2017 Dec 15. doi: 10.1002/art.40399. [Epub ahead of print]

White matter signal abnormalities in former National Football League players. Alosco ML, Koerte IK, Tripodis Y, Mariani M, Chua AS, Jarnagin J, Rahimpour Y, Puzo C, Healy RC, Martin B, Chaisson CE, Cantu RC, Au R, McClean M, McKee AC, Lin AP, Shenton ME, Killiany RJ, Stern RA. Alzheimers Dement (Amst). 2017 Nov 6;10:56-65. doi: 10.1016/j.dadm.2017.10.003. eCollection 2018.

Cell culture models of fatty acid overload: Problems and solutions. Alsabeeh N, Chausse B, Kakimoto PA, Kowaltowski AJ, Shirihai O. Biochim Biophys Acta. 2018 Feb;1863(2):143-151. doi: 10.1016/j.bbalip.2017.11.006. Epub 2017 Nov 15. Review.

A behavioral and pharmacological characterization of palatable diet alternation in mice. Moore CF, Schlain GS, Mancino S, Sabino V, Cottone P. Pharmacol Biochem Behav. 2017 Dec;163:1-8. doi: 10.1016/j.pbb.2017.10.013. Epub 2017 Oct 31.

Maternal but Not Infant Anti-HIV-1 Neutralizing Antibody Response Associates with Enhanced Transmission and Infant Morbidity. Ghulam-Smith M, Olson A, White LF, Chasela CS, Ellington SR, Kourtis AP, Jamieson DJ, Tegha G, van der Horst CM, Sagar M. MBio. 2017 Oct 24;8(5). pii: e01373-17. doi: 10.1128/mBio.01373-17.

Retromer revisited: Evolving roles for retromer in endosomal sorting. Chamberland JP, Ritter B. J Cell Biol. 2017 Nov 6;216(11):3433-3436. doi: 10.1083/jcb.201708111. Epub 2017 Oct 23.

Chronic curcumin treatment improves spatial working memory but not recognition memory in middle-aged rhesus monkeys. Moore TL, Bowley B, Shultz P, Calderazzo S, Shobin E, Killiany RJ, Rosene DL, Moss MB. Geroscience. 2017 Dec;39(5-6):571-584. doi: 10.1007/s11357-017-9998-2. Epub 2017 Oct 18.

College Binge Drinking Associated with Decreased Frontal Activation to Negative Emotional Distractors during Inhibitory Control. Cohen-Gilbert JE, Nickerson LD, Sneider JT, Oot EN, Seraikas AM, Rohan ML, Silveri MM. Front Psychol. 2017 Sep 22;8:1650. doi: 10.3389/fpsyg.2017.01650. eCollection 2017.

Genome-wide association study across European and African American ancestries identifies a SNP in DNMT3B contributing to nicotine dependence. Hancock DB, Guo Y, Reginsson GW, Gaddis NC, Lutz SM, Sherva R, Loukola A, Minica CC, Markunas CA, Han Y, Young KA, Gudbjartsson DF, Gu F, McNeil DW, Qaiser B, Glasheen C, Olson S, Landi MT, Madden PAF, Farrer LA, Vink J, Saccone NL, Neale MC, Kranzler HR, McKay J, Hung RJ, Amos CI, Marazita ML, Boomsma DI, Baker TB, Gelernter J, Kaprio J, Caporaso NE, Thorgeirsson TE, Hokanson JE, Bierut LJ, Stefansson K, Johnson EO. Mol Psychiatry. 2017 Oct 3. doi: 10.1038/mp.2017.193.

Membrane Fluidity Sensing on the Single Virus Particle Level with Plasmonic Nanoparticle Transducers. Feizpour A, Stelter D, Wong C, Akiyama H, Gummuluru S, Keyes T, Reinhard BM. ACS Sens. 2017 Oct 27;2(10):1415-1423. doi: 10.1021/acssensors.7b00226. Epub 2017 Oct 4.

Regulation of autophagy, NF-κB signaling, and cell viability by miR-124 in KRAS mutant mesenchymal-like NSCLC cells. Mehta AK, Hua K, Whipple W, Nguyen MT, Liu CT, Haybaeck J, Weidhaas J, Settleman J, Singh A. Sci Signal. 2017 Sep 12;10(496). pii: eaam6291. doi: 10.1126/scisignal.aam6291.

Basal-A Triple-Negative Breast Cancer Cells Selectively Rely on RNA Splicing for Survival. Chan S, Sridhar P, Kirchner R, Lock YJ, Herbert Z, Buonamici S, Smith P, Lieberman J, Petrocca F. Mol Cancer Ther. 2017 Dec;16(12):2849-2861. doi: 10.1158/1535-7163.MCT-17-0461. Epub 2017 Sep 6.

Identification and characterization of a potent and biologically-active PDE4/7 inhibitor via fission yeast-based assays. de Medeiros AS, Wyman AR, Alaamery MA, Allain C, Ivey FD, Wang L, Le H, Morken JP, Habara A, Le C, Cui S, Lerner A, Hoffman CS. Cell Signal. 2017 Dec;40:73-80. doi: 10.1016/j.cellsig.2017.08.011. Epub 2017 Sep 1.

The Impact of Glottal Configuration on Speech Breathing. Heller Murray ES, Michener CM, Enflo L, Cler GJ, Stepp CE. J Voice. 2017 Aug 21. pii: S0892-1997(17)30106-6. doi: 10.1016/j.jvoice.2017.07.001. [Epub ahead of print]

An RNA polymerase II-driven Ebola virus minigenome system as an advanced tool for antiviral drug screening. Nelson EV, Pacheco JR, Hume AJ, Cressey TN, Deflubé LR, Ruedas JB, Connor JH, Ebihara H, Mühlberger E. Antiviral Res. 2017 Oct;146:21-27. doi: 10.1016/j.antiviral.2017.08.005. Epub 2017 Aug 12.

CYP2C19*2 and CYP2C19*17 variants and effect of tamoxifen on breast cancer recurrence: Analysis of the International Tamoxifen Pharmacogenomics Consortium dataset. Damkier P, Kjærsgaard A, Barker KA, Cronin-Fenton D, Crawford A, Hellberg Y, Janssen EAM, Langefeld C, Ahern TP, Lash TL. Sci Rep. 2017 Aug 10;7(1):7727. doi: 10.1038/s41598-017-08091-x.

Fetal hemoglobin in sickle cell anemia: The Arab-Indian haplotype and new therapeutic agents. Habara AH, Shaikho EM, Steinberg MH. Am J Hematol. 2017 Nov;92(11):1233-1242. doi: 10.1002/ajh.24872. Epub 2017 Aug 17. Review.

Renal sodium handling and sodium sensitivity. Frame AA, Wainford RD. Kidney Res Clin Pract. 2017 Jun;36(2):117-131. doi: 10.23876/j.krcp.2017.36.2.117. Epub 2017 Jun 30. Review.

White matter damage in maintenance hemodialysis patients: a diffusion tensor imaging study. Drew DA, Koo BB, Bhadelia R, Weiner DE, Duncan S, la Garza MM, Gupta A, Tighiouart H, Scott T, Sarnak MJ. BMC Nephrol. 2017 Jul 5;18(1):213. doi: 10.1186/s12882-017-0628-0.

Video Game Rehabilitation of Velopharyngeal Dysfunction: A Case Series. Cler GJ, Mittelman T, Braden MN, Woodnorth GH, Stepp CE. J Speech Lang Hear Res. 2017 Jun 22;60(6S):1800-1809. doi: 10.1044/2017_JSLHR-S-16-0231.

Age-related changes in structural connectivity are improved using subject-specific thresholding. Bauer CM, Zajac LE, Koo BB, Killiany RJ, Merabet LB. J Neurosci Methods. 2017 Aug 15;288:45-56. doi: 10.1016/j.jneumeth.2017.06.010. Epub 2017 Jun 21.

Serum amyloid A self-assembles with phospholipids to form stable protein-rich nanoparticles with a distinct structure: A hypothetical function of SAA as a “molecular mop” in immune response. Frame NM, Jayaraman S, Gantz DL, Gursky O. J Struct Biol. 2017 Dec;200(3):293-302. doi: 10.1016/j.jsb.2017.06.007. Epub 2017 Jun 20.

Considerations for Experimental Animal Models of Concussion, Traumatic Brain Injury, and Chronic Traumatic Encephalopathy-These Matters Matter. Wojnarowicz MW, Fisher AM, Minaeva O, Goldstein LE. Front Neurol. 2017 Jun 1;8:240. doi: 10.3389/fneur.2017.00240. eCollection 2017. Review.

Targeting acetylcholine receptor M3 prevents the progression of airway hyperreactivity in a mouse model of childhood asthma. Patel KR, Bai Y, Trieu KG, Barrios J, Ai X. FASEB J. 2017 Oct;31(10):4335-4346. doi: 10.1096/fj.201700186R. Epub 2017 Jun 15.

High Glucose Induces Mitochondrial Dysfunction in Retinal Müller Cells: Implications for Diabetic Retinopathy. Tien T, Zhang J, Muto T, Kim D, Sarthy VP, Roy S. Invest Ophthalmol Vis Sci. 2017 Jun 1;58(7):2915-2921. doi: 10.1167/iovs.16-21355.

Early life allergen-induced mucus overproduction requires augmented neural stimulation of pulmonary neuroendocrine cell secretion. Barrios J, Patel KR, Aven L, Achey R, Minns MS, Lee Y, Trinkaus-Randall VE, Ai X. FASEB J. 2017 Sep;31(9):4117-4128. doi: 10.1096/fj.201700115R. Epub 2017 May 31.

Chimeric antigen receptor modified T cells that target chemokine receptor CCR4 as a therapeutic modality for T-cell malignancies. Perera LP, Zhang M, Nakagawa M, Petrus MN, Maeda M, Kadin ME, Waldmann TA, Perera PY. Am J Hematol. 2017 Sep;92(9):892-901. doi: 10.1002/ajh.24794. Epub 2017 Jun 5.

Mfn2 deletion in brown adipose tissue protects from insulin resistance and impairs thermogenesis. Mahdaviani K, Benador IY, Su S, Gharakhanian RA, Stiles L, Trudeau KM, Cardamone M, Enríquez-Zarralanga V, Ritou E, Aprahamian T, Oliveira MF, Corkey BE, Perissi V, Liesa M, Shirihai OS. EMBO Rep. 2017 Jul;18(7):1123-1138. doi: 10.15252/embr.201643827. Epub 2017 May 24.Smith

Myeloid-epithelial cross talk coordinates synthesis of the tissue-protective cytokine leukemia inhibitory factor during pneumonia. Traber KE, Symer EM, Allen E, Kim Y, Hilliard KL, Wasserman GA, Stewart CL, Jones MR, Mizgerd JP, Quinton LJ. Am J Physiol Lung Cell Mol Physiol. 2017 Sep 1;313(3):L548-L558. doi: 10.1152/ajplung.00482.2016. Epub 2017 May 18.

A split-luciferase complementation, real-time reporting assay enables monitoring of the disease-associated transmembrane protein TREM2 in live cells. Varnum MM, Clayton KA, Yoshii-Kitahara A, Yonemoto G, Koro L, Ikezu S, Ikezu T. J Biol Chem. 2017 Jun 23;292(25):10651-10663. doi: 10.1074/jbc.M116.759159. Epub 2017 May 10.

Systemic and topical use of monoclonal antibodies to prevent the sexual transmission of HIV. Anderson DJ, Politch JA, Zeitlin L, Hiatt A, Kadasia K, Mayer KH, Ruprecht RM, Villinger F, Whaley KJ.AIDS. 2017 Jul 17;31(11):1505-1517. doi: 10.1097/QAD.0000000000001521.

The TLR2 Binding Neisserial Porin PorB Enhances Antigen Presenting Cell Trafficking and Cross-presentation. Reiser ML, Mosaheb MM, Lisk C, Platt A, Wetzler LM. Sci Rep. 2017 Apr 7;7(1):736. doi: 10.1038/s41598-017-00555-4.

Prediction of Antibiotic Interactions Using Descriptors Derived from Molecular Structure. Mason DJ, Stott I, Ashenden S, Weinstein Z B, Karakoc I, Meral S, Kuru N, Bender A, Cokol M. J Med Chem. 2017 May 11;60(9):3902-3912. doi: 10.1021/acs.jmedchem.7b00204. Epub 2017 Apr 27.

Seed Location Impacts Whole-Brain Structural Network Comparisons between Healthy Elderly and Individuals with Alzheimer’s Disease. Zajac L, Koo BB, Bauer CM, Killiany R, Behalf Of The Alzheimer’s Disease Neuroimaging Initiative. Brain Sci. 2017 Apr 6;7(4). pii: E37. doi: 10.3390/brainsci7040037.

Broad induction of immunoregulatory mechanisms after a short course of anti-IL-7Rα antibodies in NOD mice. Vazquez-Mateo C, Collins J, Fleury M, Dooms H. BMC Immunol. 2017 Mar 29;18(1):18. doi: 10.1186/s12865-017-0201-4.

Ebolaviruses Associated with Differential Pathogenicity Induce Distinct Host Responses in Human Macrophages. Olejnik J, Forero A, Deflubé LR, Hume AJ, Manhart WA, Nishida A, Marzi A, Katze MG, Ebihara H, Rasmussen AL, Mühlberger E. J Virol. 2017 May 12;91(11). pii: e00179-17. doi: 10.1128/JVI.00179-17. Print 2017 Jun 1.

CLASP2 Links Reelin to the Cytoskeleton during Neocortical Development. Dillon GM, Tyler WA, Omuro KC, Kambouris J, Tyminski C, Henry S, Haydar TF, Beffert U, Ho A. Neuron. 2017 Mar 22;93(6):1344-1358.e5. doi: 10.1016/j.neuron.2017.02.039. Epub 2017 Mar 9.

Microglia activation and phagocytosis: relationship with aging and cognitive impairment in the rhesus monkey. Shobin E, Bowley MP, Estrada LI, Heyworth NC, Orczykowski ME, Eldridge SA, Calderazzo SM, Mortazavi F, Moore TL, Rosene DL. Geroscience. 2017 Apr;39(2):199-220. doi: 10.1007/s11357-017-9965-y. Epub 2017 Feb 25.

Systemic insulin sensitivity is regulated by GPS2 inhibition of AKT ubiquitination and activation in adipose tissue. Cederquist CT, Lentucci C, Martinez-Calejman C, Hayashi V, Orofino J, Guertin D, Fried SK, Lee MJ, Cardamone MD, Perissi V. Mol Metab. 2016 Oct 31;6(1):125-137. doi: 10.1016/j.molmet.2016.10.007. eCollection 2017 Jan.

Structure of serum amyloid A suggests a mechanism for selective lipoprotein binding and functions: SAA as a hub in macromolecular interaction networks. Frame NM, Gursky O. Amyloid. 2017 Mar;24(sup1):13-14. doi: 10.1080/13506129.2016.1270930. Epub 2016 Dec 31. No abstract available.

Central Ghrelin Resistance Permits the Overconsolidation of Fear Memory. Harmatz ES, Stone L, Lim SH, Lee G, McGrath A, Gisabella B, Peng X, Kosoy E, Yao J, Liu E, Machado NJ, Weiner VS, Slocum W, Cunha RA, Goosens KA. Biol Psychiatry. 2017 Jun 15;81(12):1003-1013. doi: 10.1016/j.biopsych.2016.11.009. Epub 2016 Nov 29.

Pathological Overeating: Emerging Evidence for a Compulsivity Construct. Moore CF, Sabino V, Koob GF, Cottone P. Neuro-psychopharmacology. 2017 Jun;42(7):1375-1389. doi: 10.1038/npp.2016.269. Epub 2016 Dec 6. Review.

The Trace Amine-Associated Receptor 1 Agonist RO5256390 Blocks Compulsive, Binge-like Eating in Rats. Ferragud A, Howell AD, Moore CF, Ta TL, Hoener MC, Sabino V, Cottone P. Neuropsychopharmacology. 2017 Jun;42(7):1458-1470. doi: 10.1038/npp.2016.233. Epub 2016 Oct 6.

Immunologic environment influences macrophage response to Porphyromonas gingivalis. Papadopoulos G, Shaik-Dasthagirisaheb YB, Huang N, Viglianti GA, Henderson AJ, Kantarci A, Gibson FC 3rd. Mol Oral Microbiol. 2017 Jun;32(3):250-261. doi: 10.1111/omi.12168. Epub 2016 Aug 26.