Past Resident Publications and Presentations

mecharm_.jpg (23329 bytes)Ambrose Pare described mechanical arms for patients who had undergone amputation Publications and Presentations by Past Surgical Residents
Joseph Frenkel, MD
Book chapter: “Palliative Options and Procedures for Treatment of Esophageal Cancer.” In: Adult Chest Surgery: Concepts and Procedures, Editor: Sugarbaker DJ,
The McGraw-Hill Companies, New York, Publication: pending.

Hector Simosa, M.D.

 

Wang GJ, Sui XX, Simosa HF, Jain MK, Altieri DC, Conte MS. Regulation of vein graft hyperplasia by survivin, an inhibitor of apoptosis protein. Brigham and Women’s Hospital and Harvard Medical School, Boston, MA & University of Massachusetts Medical School, Worcester, MA. Arterioscler Thromb Vasc Biol. 2005 Oct; 25(10):2081-7.

 

Simosa HF, Wang G, Sui XX, Peterson T, Narra V, Altieri DC, Conte MS. Survivin expression is upregulated in vascular injury and identifies a distinct cellular phenotype. Brigham and Women’s Hospital and Harvard Medical School, Boston, MA & University of Massachusetts Medical School, Worcester, MA. J Vasc Surg. 2005 Apr; 41(4):682-90.

 

Simosa HF, Conte MS. Genetic therapy for vein bypass graft disease: Current perspectives. Brigham & Women’s Hospital, Harvard Medical School, Boston, MA. Vascular. 2004 Jul-Aug; 12(4):213-7.

 

Simosa HF, Aquino M, Hirsch EF. Chylous retroperitoneum: A rare presentation of blunt thoracic duct injury. Boston University Medical Center, Boston, MA. J. Trauma (In press) 2005.

Conte MS, Mann MJ, Simosa HF, Rhynhart KK, Mulligan, RC. Genetic interventions for vein bypass graft disease. A review. Department of Surgery, Brigham & Women’s Hospital & Harvard Institute for Human Genetics, Harvard Medical School, Boston, MA. J Vasc Surg. 2002 Nov;36(5):1040-52.

 

Blanc-Brude OP, YU J, Simosa HF, Conte MS, Sessa WC, Altieri DC. IAP survivin regulates vascular injury. Yale University School of Medicine, New Haven, CT. & Brigham & Women’s Hospital, Harvard Medical School, Boston, MA. Nature Med 2002 Sept;8(9):987-994

 

Moreno PR, Fallon JT, Murcia AM, Leon MN, Simosa H, Fuster V, Palacios IF. Tissue characteristics of restenosis after percutaneous transluminal coronary angioplasty in diabetic patients. Massachusetts General Hospital, Harvard Medical School, Boston. MA.J Am Coll Cardiol. 1999 Oct; 34(4): 1045-9.

 

Leon MN, Harrell LC, Simosa HF, Mahdi NA, Pathan A, Lopez-Cuellar J, Inglessis I, Moreno PR, Palacios IF. Mitral balloon valvotomy for patients with mitral stenosis in atrial fibrillation: immediate and long-term results. Massachusetts General Hospital, Harvard Medical School, Boston. MA. J Am Coll Cardiol. 1999 Oct; 34(4): 1145-52.

 

Pathan AZ, Mahdi NA, Leon MN, Lopez-Cuellar J, Simosa H, Block PC, Harrell L, Palacios IF. Is redo percutaneous mitral balloon valvuloplasty (PMV) indicated in patients with post-PMV mitral restenosis? Massachusetts General Hospital, Harvard Medical School, Boston. MA. J Am Coll Cardiol. 1999 Jul; 34(1): 49-54

 

Leon MN, Harrell LC, Simosa HF, Mahdi NA, Pathan AZ, Lopez-Cuellar J, Palacios IF. Comparison of immediate and long-term results of mitral balloon valvotomy with the double-balloon versus Inoue techniques. Massachusetts General Hospital, Harvard Medical School, Boston, MA. Am J Cardiol. 1999 May 1; 83(9): 1356-63.

 

Lopez-Cuellar J, Leon MN, Pathan AZ, Mahdi NA, Simosa HF, McMellon C, Palacios IF. Ten year follow-up of optimal candidates for percutaneous mitral balloon valvuloplasty. Massachusetts General Hospital, Harvard Medical School, Boston, MA. Circulation, 1997 Oct; 96 (8S): 396-1.

 

Presentations/Abstracts:

Wang GJ, Lam D, Simosa HF, Sui XX, Conte MS. Adventitial angiogenesis and vein graft hyperplasia: role of an inhibitor of apoptosis protein, survivin. Department of Vascular Surgery, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA. Presented at the Society for Clinical Vascular Surgery, Coral Gables, FL. March 2005.

 

Simosa HF, Blanc-Brude OP, Narra V, Altieri DC, Conte MS. IAP Survivin regulates vascular injury. Department of Vascular Surgery, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA; University of Massachusetts Medical School, Worcester, MA. Presented at the ACS/Surgical Forum. Chicago, IL. October 2003.

 

Simosa HF, Blanc-Brude OP, Narra V, Altieri DC, Conte MS. Survivin, an inhibitor of apoptosis is cytoprotective in vascular smooth muscle cells and regulates lesion development following balloon angioplasty. Department of Vascular Surgery, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA; Boyer Center For Molecular Medicine Yale University Medical School, New Haven, Connecticut. Presented at the BWH Research Session. Boston, MA. March 2003.

 

Simosa HF, Blanc-Brude O, Narra V, Altieri DC, Conte MS. Survivin, an inhibitor of apoptosis is cytoprotective in vascular smooth muscle cells and is upregulated during lesion development following balloon angioplasty. Brigham and Women’s Hospital, Harvard Medical School, Boston, MA. Presented at the AAVS/SVS Joint annual meeting, Boston, MA. June 9, 2002.

 

Sabine Manoli, M.D.
 

Natarajan S, Manoli S, Basnyat PS, Bransom CJ, Jones RD: Spontaneous rupture of primary musculoskeletal hydatid cyst”. Surgery. 132(3): 533-4, 2002 

A. Brent Fruin, M.D.
 
Shebani, K.O., Stucchi, A.F., Fruin, A.B., McClung, J. Gee, D,, Beer, E. LaMorte, W.W. Becker, J.M. Pouchitis in A Rat Model of Ileal J Pouch-Anal Anastomosis. Inflammatory Bowel Diseases, 8(1):23-34, 2002.

Reed, KL, Fruin , AB , Stucchi, AF, Leeman, SE, Gower, AC, and Becker, JM. The role of substance P in intra-abdominal adhesion formation.  J Surg Res, 108:165-172, 2002.

Fruin , AB , el-Zammar, O, O’Brien, MO, Stucchi, A, and Becker, JM.  Colonic Metaplasia in the Ileal Pouch is Associated with Inflammation and is Not the Result of Long-Term Adaptation.  J Gastrointestinal Surg 7:246-254, 2003.

Stucchi, AF., Shebani, KO., Leeman, LE.,Wang, CC., Reed, KL., Fruin, AB., Gower, AC., McClung, JP., Andry, CD., O’Brien, MO., Pothoulakis, C. and Becker, JM., A Neurokinin 1 Receptor Antagonist Reduces an Ongoing Ileal Pouch Inflammation, and the Response to a Subsequent Inflammatory Stimulus. Am J Phys.  285: G1259-G1267, 2003.

Reed, KL, Fruin , AB , Gower, AC, Stucchi, AF., Leeman, SE., and Becker, JM. A substance P receptor antagonist decreases post-surgical intraabdominal adhesion formation in a rat model by increasing peritoneal fibrinolytic activity.  Proc Natl Acad Sci U S A. 101(4):9115-9120, 2004.

Yantiss, RK., Sapp, H., Farraye, FA., El-Zammer, O., O’Brien, MJ., Fruin, AB., Stucchi, AF., Brien, T., Becker, JM., and Odze, RD.  Histologic Predictors of Pouchitis in Patients with Chronic Ulcerative Colitis.  Am J Surg Path  28(8):999-1006, 2004.

Reed, KL, Fruin , AB , Gower, AC, Gonzales, K., Stucchi, AF., Andry, C, O’Brien, M, and Becker, JM. NFkB preceeds Increases in mRNA Encoding Nuerokinin-1 Receptor, Inflammatory Cytokines and Adhesion Molecules in DSS-induced colitis in rats. Dig Dis Sci. (50)12:2366-2378, 2005.

Yantiss, RK., Farraye, FA., O’Brien, MJ., Fruin, AB., Stucchi, AF., Becker, JM., Reddy, SI., Odze, RD. Prognostic Significance of Superficial Fissuring Ulceration in Patients with Severe “Indeterminate” Colitis. Am J Surg Path 30(2):165-170, 2006.

El-Zammar, O., Fruin , AB , Stucchi, AF., Gee, D., Becker, JM. and O’Brien, MJ. Status of the vermiform appendix in ulcerative colitis:An assessment in a series of 86 proctocolectomies. Modern Pathology 14(1) 84A, 2001

Fruin , AB , Reed, KL, Stucchi, AF, Leeman, SE, Gower, AC, and Becker, JM. The role of substance P in intra-abdominal adhesion formation.  J Surg Res, 100(2): 293, 2001.

Saap, H., Farraye, F., O’Brien, MJ., Becker, JM., Fruin, AB., el-Zammar, O, Stucchi, AF., and Odze, RD. Severe pancolitis, early fissuring, ulceration, and severe involvement of the appendix are associated with the development of pouchitis after colectomy for ulcerative colitis. Modern Pathology, 15 (1) 143A, 2002.

Reed, KL, Fruin , AB , Gower, AC, Stucchi, AF, Andry, C, O’Brien, M, and Becker, JM. NFkB activation is an early inflammatory event that precedes the upregulation of proinflammatory cytokines and adhesion molecules in DSS-induced colitis in rats. Gastroenterology 122(4) A396, 2002.

Fruin , AB , el-Zammar, O, O’Brien, M, Stucchi, A, and Becker, JM.  Colonic Metaplasia in the Ileal Pouch is Associated with Inflammation and is Not the Result of Long-Term Adaptation.  Gastroenterology 123(1) 2, 2002.

Fruin , AB , Stucchi, AF, and Becker, JM.  The incidence and treatment of fungal pouchitis following ileal pouch-anal anastomosis. Diseases of the Colon and Recum 45(3) A50 2002.

Phillip Cohen, M.D.

Cohen, PA., Aarons, CB., Brahmbhatt, JV., Reed, KL, Gower, AC., Stucchi, AF., Leeman, SE., and Becker, MD, JM. The first 24 hours following laparotomy are critical in the development of Postoperative Adhesions.  Accepted SUS 2005

Reed, KL., Gower, A., Stucchi, AF., Steelman, K., Cohen, PA., Overman, K., Leeman, SE., Becker, JM., Substance P may Promote Intraabdominal Adhesion Formation by Decreasing Peritoneal Fibrinolytic Activity.  Gastroenterology 126(4):A557, 2004.

Cohen , PA. , Reed, KL., Gower, AC., Stucchi, AF. Lehrmann, J., Fruin, AB., Leeman, SE., Becker, JM.  A Substance P Receptor Antagonist that Reduces Intraabdominal Adhesion Formation Decreases Peritoneal Matrix Metalloproteinase Activity.  J AM College Surg. 199(3S): S21-S22, 2004.

Jill Lehrmann, M.D.

Lehrmann, J, Stucchi, AF,  LaMorte, WW, Herron, T, Becker, JM. Complications and Outcomes After Ileal Pouch-Anal Anastomosis (IPAA): A Meta-Analysis of more than 8300 Patients. Gastroenterology 124(4) A814, 2003

Reed, KL, Lehrmann, JF,  Stucchi, AF, Gower, AC, Leeman, SE, Becker, JM. Administration of a substance P receptor antagonist increases the expression of peritoneal tissue plasminogen activator in a rat model of intraabdominal adhesions. Gastroenterology 124(4), A299, 2003.

Lehrmann, JF., Reed, KL, Gower, AC, Stucchi, AF., Leeman SE. and Becker, JM,  Substance P Activates MAP Kinase, Downregulates Matrix Metalloproteinase 3 and Increases Collagen-type III mRNA levels in Cultured Peritoneal Mesothelial Cells. American College of Surgeons, J AM College Surg 197(3)S17-S18, 2003.  

Noah Rosen, M.D.
Presentations:

Society for Clinical Vascular Surgery – Coral Gables , Fla : March 2005; “The Effect of a Surgical Resident as Assistant for Carotid Endarterectomy.”

Massachusetts Chapter of the American College of Surgeons – Boston , MA : Nov. 2004; “A Comparison of Cerebral Oximetry to EEG as a Monitor of Cerebral Ischemia during Carotid Endarterectomy.”

Association for Academic Surgery - Boston , MA : Nov 2002; “Perflubron Emulsion Increases Subcutaneous Tissue Oxygen Tension.”

International Society of Oxygen Tissue Transport - Manchester , England : Aug 2002; “Perflubron Emulsion Increases Subcutaneous Tissue Oxygen Tension.”

Wound Healing Society – Baltimore , MD : May 2002; “Perflubron Emulsion Increases Subcutaneous Tissue Oxygen Tension in an Animal Model.”

Association for Academic Surgery – Milwaukee , WI : Nov 2001; “Near-Infrared Spectrometric Determination of Blood pH.”

  Publications:        

Rosen NA, Hopf HW, Hunt TK. Perflubron emulsion increases subcutaneous tissue oxygen tension in rats. Wound Rep Reg; 14; 2006; pp. 55-60.  

Rosen NA, Hopf HW, Hunt TK. Oxygen and wound healing. In: Falabella, Kirsner, eds.  Wound Healing. Marcel Dekker, Inc, 2005; pp. 563-573.  

Odilo T, Wagner S, Wicke C, Scheuenstuhl H, Hussain MZ, Rosen N, Seremetiev A, Becker HD, Hunt TK. Lactate and oxygen constitute a fundamental regulatory mechanism in wound healing. Wound Rep Reg; 11; 2003; pp. 504-509.  

Rosen NA, Charash WE, Hirsch EF. Near-infrared spectrometric determination of blood pH. J Surg Res; 106; 2002; pp. 282-286.  

Patent:

Rosen NA, Kohl BA. Transbronchial reflectance oximetric measurement of mixed venous oxygen saturation, and device therefor. U.S. Patent 6,961,600 B2, Nov 1, 2005 .

Jeffrey Kalish, M.D.
Presentations:

Monahan TS, Panossian H, Andersen ND, Kalish JA, Contreras MA, Phaneuf MD, Ferran CJ, LoGerfo FW.  The role of OB-cadherin in vascular smooth muscle cell migration and proliferation.  Oral presentation by Dr. Monahan at New England Society for Vascular Surgery (NESVS) Annual Meeting, September 2005.

 

Kalish JA, Monahan TS, Contreras MA, LoGerfo FW.  The Protective Role of OB-Cadherin during Cellular Proliferation in Vein Graft Remodeling.  Oral presentation at Society of University Surgeons (SUS) Annual Meeting, February 2005.

 

Monahan TS, Andersen ND, Popescu-Vladimir A, Contreras MA, Phaneuf MD, Daniel SL, Shrikhande GV, Kalish JA, Ferran CJ, LoGerfo FW.  RNA Interference Targeting MARCKS Arrests Human Vascular Smooth Muscle Cell Proliferation In Vitro and Ex Vivo.  Oral presentation by Dr. Monahan at Society of University Surgeons (SUS) Annual Meeting, February 2005.

 

Monahan TS, Contreras MA, Kalish JA, Phaneuf MD, Bide MJ, Dempsey DJ, Mitchell RN, LoGerfo FW, Hamdan AD.  In vivo testing of an infection resistant prosthetic material.  Oral presentation by Dr. Monahan at American College of Surgeons (ACS), October 2004.

 

Contreras MA, Monahan TS, Kalish JA, Phaneuf MD, Dempsey DJ, Mitchell RN, Quist WC, LoGerfo FW.  In Vivo Evaluation of a New Dacron-Polyurethane Surface with Vascular Endothelial Cell Growth Factor and Recombinant Hirudin.  Oral presentation by Dr. Contreras at Federation of American Societies for Experimental Biology (FASEB), April 2004.

 

Deutsch ER, Phaneuf MD, Willis DJ, Bide MJ, Kalish JA, LoGerfo FW, Quist WC.  Development of a Biologically Active Dacron Vascular Graft Surface.  Oral presentation by Dr. Deutsch at Association for Academic Surgery (AAS) Annual Meeting, November 2003.

 

Kalish JA, Willis DJ, Link JJ, Deutsch ER, Contreras MA, LoGerfo FW, Quist WC.  Evaluation of Hypoxia-Related Gene Expression in Autologous Vein Bypass Grafts Using Microarray Analysis.  Oral presentation at American College of Surgeons (ACS) Annual Meeting, October 2003.

 

Kalish JA, Willis DJ, Deutsch ER, Contreras MA, LoGerfo FW, Quist WC.  Temporal Up-Regulation and Localization of OB-Cadherin Following Vein Bypass Grafting.  Oral presentation at New England Society for Vascular Surgery (NESVS) Annual Meeting, September 2003.

 

Kalish JA, Willis DJ, Link JJ, Deutsch ER, Contreras MA, LoGerfo FW, Quist WC.  Genomic Expression Patterns in Vein Graft Remodeling.  Oral presentation at NHLBI Symposium (From Genome to Disease: A Symposium of High Throughput Biology), July 2003.

 

Kalish JA, Willis DJ, Link JJ, Deutsch ER, Contreras MA, LoGerfo FW, Quist WC.  Application of Microarrays and Hierarchical Clustering to Assess Early Vein Graft Remodeling.  Oral presentation at Federation of American Societies for Experimental Biology (FASEB) Annual Meeting, April 2003.

 

Kalish JA, Willis DJ, Link JJ, Deutsch ER, Contreras MA, LoGerfo FW, Quist WC.  Temporal Gene Expression in Vein Bypass Grafts Using Microarray Analysis.  Oral presentation at United States and Canadian Academy of Pathology (USCAP) Annual Meeting, March 2003.

 

Joseph KA, Kalish J, Yee H, Shamamian P.  Necrotizing Pancreatitis Results in Local and Systemic Upregulation of Transforming Growth Factor b1 (TGFb1): Evidence for a Common Mechanism of Injury. Poster Presentation at The Society for Surgery of the Alimentary Tract (SSAT) Annual Meeting, May 1999.

 

Joseph KA, Kalish J, Tinglin J, Yee H, Galloway A, Shamamian P.  Increased Expression of Transforming Growth Factor b1 (TGFb1) is Independent of Severity of Pancreatitis.  Oral presentation by Dr. Joseph at The Society of University Surgeons (SUS) Resident’s Program, February 1999.

 

Jacobowitz GR, Kalish JA, Lee AM, Adelman MA, Riles TS, Landis R.  Long-term Follow-up of Saphenous Vein, Internal Jugular Vein, and Knitted Dacron Patches for Carotid Artery Endarterectomy.  Poster presentation at Stroke Council 23rd International Joint Conference on Stroke and Cerebral Circulation, February 1998.

 

 

Publications:

 

Kalish JA, Babineau TJ.  PET scans in tumor staging: hope or hype?  Curr Surg. (In press).

 

Kalish JA, LoGerfo FW.  Diabetic foot and vascular complications.  In DeGroot LJ, Jameson JL (eds): Endocrinology. Philadelphia, Elsevier, 2006, pp 1367-1373.

 

Lorber J, Kalish J, Farraye FA, Cerda S, Babineau TJ.  Glomus tumor of the gastric antrum: case report.  Curr Surg 2005;62:436-438.

 

Willis DJ, Kalish JA, Li C, Deutsch ER, Contreras MA, LoGerfo FW, Quist WC.  Temporal gene expression following prosthetic arterial grafting.  J Surg Res 2004;120:27-36.

 

Kalish JA, Willis DJ, Li C, Link JJ, Deutsch ER, Contreras MA, Quist WC, LoGerfo FW.  Temporal genomics of vein bypass grafting through oligonucleotide microarray analysis.  J Vasc Surg 2004;39;645-654.

 

Jacobowitz GR, Kalish JA, Lee AM, Adelman MA, Riles TS, Landis R. Long-term Follow-up of Saphenous Vein, Internal Jugular Vein, and Knitted Dacron Patches for Carotid Artery Endarterectomy.  Annals of Vascular Surgery 2001; 15: 281-287.

 

Elizabeth Renaud, M.D.
Presentations:
Renaud, E., H. Patel, S.L. Moulton.  “Perioperative Care for the Pediatric Patient” in Essentials of Surgery, Becker, J., ed.  Elsevier (submitted). 

Renaud, E, E. Oliva, B. Rueda, D. MacLaughlin and P.K. Donahoe.  “Endometrial Cancer is a Receptor Mediated Target for Mullerian Inhibiting Substance.”  PNAS, January 2005, Vol 102:111-116. 

 

Renaud, E., D. Liu, D. Teitelbaum.  “Inferior Vena Cavectomy for Wilms’ Tumor: An Unusual Variant.”  Journal of Pediatric Surgery, March 2001, Vol. 36 No 3, pp. 526-529.

 

Teitelbaum, D., A. Coran, E. Renaud, T. Durant, R. Ciley, D. Bliss, N. Sherman.  “Primary Endorectal Pull-Through for Hirschsprung’s Disease: A Multicenter Study.”  Annals of Surgery, September 2000, Vol. 232, No. 3, pp. 372-380.

 

Felt, B., E. Mollen, S. Diaz, E. Renaud, M. Zeglis, G. Wheateroft, D. Mendelow.  “Behavioral Interventions Reduce Infant Distress at Immunizations.”  Archives of Pediatric and Adolescent Medicine, July 2000, Vol. 154 No. 7, pp. 719-724.

Publications

Renaud, E., E. Oliva, B. Rueda, D. MacLaughlin, and P.K. Donahoe.  “Endometrial Cancer Expresses the Mullerian Inhibiting Substance (MIS) Type II receptor and is Growth Inhibited by MIS.”  Presentation at the American College of Surgeons Clinical Congress, October 2004.

 

Renaud, E., D.T. MacLaughlin, E. Oliva, and P.K. Donahoe.  “The Role of Mullerian Inhibiting Substance and Its Type II Receptor in Growth Inhibition of Endometrial Cancer.”   Poster Presentation at the Annual Meeting of the American Pediatric Surgical Association, May 2004.

 

Renaud, E., D.T. MacLaughlin, E. Oliva, and P.K. Donahoe.  “The Role of Mullerian Inhibiting Substance and The Mullerian Inhibiting Substance Type II Receptor in Growth Inhibition of Endometrial Cancer.”  Presentation, Grasberger Research Symposium, Boston University Medical Center, February 9, 2004.

 

Renaud, E., H. Patel, S. Moulton.  “Incidental Appendectomy during Laparoscopic Splenectomy in Children with Sickle Cell Anemia – New, Safe, and Worth It.”  Poster Presentation, 12th Congress for Endosurgery in Children Sponsored by the International Pediatric Endosurgery Group, March 10-13, 2003.

John Jones, M.D.
 Presentations: 
Jones J: Transthoracic echocardiography in the evaluation of pulmonary hypertension in rats.”  Oral presentation.American Heart Association – 2001. 

 Jones J: 5-Lipoxygenase accelerates the development of pulmonary hypertension in monocrotaline-treated rats. Poster presentation presented at the 7th International Conference on Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation and Related Diseases. 

Publications:
 Forgione MA, Cap A, Liao R, Moldovan NI, Eberhardt RT, Lim CC, Jones J, Goldschmidt-Clermont PJ, Loscalzo J.  Heterozygous cellular glutathione peroxidase deficiency in the mouse: abnormalities in vascular and cardiac function and structure. Circulation. 2002 Aug 27;106(9):1154-8. 
 
 Jones J, Mendes L, Rudd MA, Russo G, Loscalzo J, Zhang YY. Serial noninvasive assessment of progressive pulmonary hypertension in a rat model. Am J Physiol Heart Circ Physiol. 2002 Jul;283(1):H364-71.
Primary teaching affiliate
of BU School of Medicine