Ongoing and Graduated ARCs:
(Note: In addition to intra-ARC collaborations, there are also ongoing inter-ARCs collaborations)
A. ARCs
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Host-pathogen interaction: the case of Pneumonia (PneumoniARC) (1.1.16)
Director: Dr. Joseph (Jay) Mizgerd (jmizgerd@bu.edu)
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Thrombosis to Hemostasis in Health and Disease (1.1.15)
Co-Directors: Dr. Vipul Chitalia (vichital@bu.edu), Dr. Jean Francis (jean.francis@bmc.org), Dr. Mark Sloan (mark.sloan@bmc.org), and Dr. Katya Ravid (kravid@bu.edu)
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ETIOLOGY AND PATHOGENESIS OF ORAL CANCER (EPOC)
Drs. Maria Kukuruzinsa (mkukuruz@bu.edu), Avrum Spira (aspira@bu.edu) and Maria Trojanowska (trojanme@bu.edu), ARC Directors (1.1.14)
B. ARC-Programs
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NANOTHERANOSTIC PLATFORMS FOR CANCER AND VASCULAR DISEASE
Drs. Mark Grinstaff (mgrin@bu.edu), Victoria L.M. Herrera (vherrera@bu.edu), Joyce Y. Wong (jywong@bu.edu) and Karl J. Karlson (kkarlson@bu.edu), ARC Directors (1.1.12)
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MITOCHONDRIA IN HEALTH AND DISEASE
Dr. Orian Shirihai, ARC Director (shirihai@bu.edu) (2.1.09)
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MOLECULAR, BIOMECHANICAL AND GENETIC MECHANISMS OF ARTERIAL STIFFNESS
Drs. Richard A. Cohen (racohen@bu.edu), Kathleen Morgan (kmorgan@bu.edu) and Francesca Seta (setaf@bu.edu), ARC Directors (12.1.10)
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PROTEIN TRAFFICKING AND NEURODEGENERATIVE DISEASE
Dr. Lindsay Farrer, ARC Director (farrer@bu.edu) (12.1.09)
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SEX DIFFERENCES IN ADIPOSE TISSUE BIOLOGY AND RELATED METABOLIC DISEASE
Dr. Susan Fried, ARC Director (skfried@bu.edu) (12.1.09)
C. ARCs graduated into centers or PPG or other
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iPS Bank (in collaboration with CReM)
Drs. Darrell N. Kotton and Gustavo Mostoslavsky, ARC Directors (dkotton@bu.edu; gmostosl@bu.edu) (2.1.09)
***successful completion of ARC research with achievement of a formal university-recognized Center for Regenerative Medicine***
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CARDIOVASCULAR CONSEQUENCES OF METABOLIC DISEASE
Dr. Kenneth Walsh (kxwalsh@bu.edu), ARC Director
***successful completion with achievement of an NHLBI-funded PPG ( Grant Number: 2P01HL081587-06A1; Principal Investigator: KENNETH WALSH; Project Title: Metabolic Control of Endothelial Cell Phenotype; Project Period: 04/1/2011- 2/29/2016)***
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BIOMARKERS OF DISEASE
Dr. Mark McComb (mccomb@bu.edu), ARC Director, and Drs. Richard Cohen (racohen@bu.edu), and Catherine Costello (cecmsms@bu.edu), ARC co-Directors (12.1.09)
***ARC Directors re-directed efforts into a newly funded NIH grant to support a National Proteomic Center at BU***
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OBESITY, CANCER AND INFLAMMATION
Dr. Gerald Denis (gdenis@bu.edu), ARC Director, and Dr. Barbara Nikolajczyk (bnikol@bu.edu), ARC Co-Director (12.1.10)
***In 12.1.12, members of this ARC joined other ARCs focused on metabolic disease and obesity (see above), thus enhancing collaborative capabilities ***
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CALCIUM HOMEOSTASIS IN HEALTH AND DISEASE
Drs. Victoria Bolotina (bolotina@bu.edu) and Mike Kirber (mkirber@bu.edu), ARC Directors (12.1.10)
***ARC obtained Foundation Funding to develop Parkinson Disease-related research***
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COMPUTATIONAL GENOMIC MODELS OF ENVIRONMENTAL & CHEMICAL CARCINOGENICITY
Drs. Stefano Monti (smonti@bu.edu) and David Sherr (dsherr@bu.edu), ARC Directors (1.1.13)
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METABOLIC DISEASES AND INSULIN RESISTANCE: STUDIES IN PATIENTS UNDERGOING BARIATRIC SURGERY
Dr. Ruderman, ARC Director (nrude@bu.edu); Drs. Caroline Apovian (capovian@bu.edu) and Konstantin Kandror (kkandror@bu.edu), Co-Directors,(1.1.12)
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ATRIAL FIBRILLATION: EPIDEMIOLOGY AND GENOMICS IN AN URBAN CARE CENTER
Jared W. Magnani, MD (jared.magnani@bmc.org), ARC Co-Director, and Emelia J. Benjamin, MD, ScM (emelia@bu.edu), ARC Co-Director (12.1.10, funding did not matriculate)
***ARC Directors developing infrastructure***
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BLOOD MICROBIOME
Drs. Marie E. McDonnell (Marie.McDonnell@bmc.org) and Lisa Ganley-Leal (Lisa.GanleyLeal@bmc.org), ARC Directors (2.1.09)
*In 2011, members of this ARC joined other related ARCs, as the Microbiome initiative was halted upon transition of leading faculty to other institution*
