The Website of Mengwei Zang’s Laboratory

AMPK, SREBP, and Lipid Metabolism

Dr. Yu Li’s oral presentations in ADA webcasts (2010) (2011)

AMPK Phosphorylates and Inhibits SREBP Activity to Attenuate Hepatic Steatosis and Atherosclerosis in Diet-induced Insulin Resistance

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The Synthetic Polyphenol, S17834, Attenuates Accelerated Aortic Atherosclerosis in Insulin Resistant LDLR-/- mice

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Confocal Microscopy Image of Increased Nuclear SREBP-1 (Green) in the Hepatocytes of Insulin Resistant Mice and Eliminated by S17834 Treatment

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AMPK Directly Phosphorylates human SREBP-1c at Ser372 in vitro

Phospho-SREBP-1c (Ser372) antibody is available in Cell Signaling Technology (#9874) (http://www.cellsignal.com/products/9874.html)

Slide 1

AMPK Phosphorylates and Inhibits SREBP Activity to Attenuate Hepatic Steatosis and Atherosclerosis in Diet-induced Insulin Resistance

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December 29, 2011
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