Katrina Steiling, M.D, M.Sc.
B.S., Boston College, Chestnut Hill, MA
M.D. Boston University School of Medicine, Boston, MA
Internal Medicine Residency, Boston University Medical Center, Boston, MA
Postdoctoral Research Fellowship, Pulmonary Center, Boston University Medical Center, Boston, MA
Pulmonary/Critical Care Fellowship, Boston University Medical Center, Boston, MA
M.Sc., Bioinformatics, College of Engineering, Boston University, Boston, MA
Internal Medicine Board Certifications, Pulmonary Disease, Critical Care Medicine
Dr. Steiling’s research focuses on applying high-throughput genomic tools and emerging computational methods to develop improved diagnostics, prognostics, and risk stratification tools for phenotypically complex lung diseases such as COPD and lung cancer. Dr. Steiling’s primary research involves gene expression profiling of the airway epithelium from individuals with COPD in order to understand the molecular mechanisms of this disease and its relationship to lung cancer. She has also worked to apply airway gene expression profiling to the diagnosis of lung cancer, to understand the relationship between smoking-induced changes in gene expression in the bronchial airway and the upper airway, and to elucidate the relationship between smoking-induced changes in airway gene and protein expression.
Gower AC, Steiling K, Brothers JF, Lenburg ME, Spira A. “Transcriptomic studies of the airway ‘field of injury’ associated with smoking-related lung disease.” Proc Am Thorac Soc, 2011; 8(2):173-179.
Brody JS, Steiling K. “Interaction of cigarette exposure and airway epithelial cell gene expression” Annu Rev Physiol. 2011; 73:437-456.
Spira A, Steiling K. Topics in genetics and genomics: Gene Expression. In: UpToDate, Basow DS (Ed), UpToDate, Waltham, MA, 2010.
Steiling K, Lenberg ME, Spira A. “Airway Gene Expression in Chronic Obstructive Pulmonary Disease.” Proc Am Thorac Soc. 2009;6:697-700.
Steiling K, Kadar AY, Bergerate A, Flanigon J, Sridhar S, Shah V, Ahmad QR, Brody JS, Lenburg ME, Steffen M, Spira A. “Comparison of proteomic and transcriptomic profiles in the bronchial airway epithelium of current and never smokers.” PLoS ONE. 2009;4(4):e5043.
Steiling K, Ryan J, Brody JS*, Spira A*. “The field of tissue injury in the lung and airway.” Cancer Prevention Research, 2008; 1(6):396-403. *contributed equally as senior author