Avrum Spira, MD, MSc, to Co-lead Project to Intercept Lung Cancer
Lung cancer remains the leading cause of cancer deaths in the United States, with someone diagnosed approximately every two minutes. In a collaborative effort to end this devastating disease, the American Lung Association and LUNGevity Foundation have joined forces to invest $3 million over the next three years in research aimed at intercepting lung cancer […]
Researchers Shed Light on Signaling Pathway Responsible for Head and Neck Cancers
A new study from researchers at Boston University Chobanian & Avedisian School of Medicine shows how computational approaches can drive important biomedical discoveries. The study aimed to better characterize oral tumor heterogeneity, including aggressive cell subpopulations, and identify candidate vulnerabilities that could be targeted therapeutically. The findings are of timely significance, providing new information about […]
Centenarians Possess Unique Immunity that Helps them Achieve Exceptional Longevity
Led by researchers from Boston University Chobanian & Avedisian School of Medicine and Tufts Medical Center, a new study finds centenarians harbor distinct immune cell type composition and activity and possess highly functional immune systems that have successfully adapted to a history of sickness allowing for exceptional longevity. These immune cells may help identify important […]
Two Technologies That Can Make Diagnosing Dementia Easier for Doctors and Patients
(Source: The Brink) Dr. Vijaya Kolachalama, Associate Professor of Medicine and CBM faculty member, was quoted in the Brink article “Two Technologies That Can Make Diagnosing Dementia Easier for Doctors and Patients.” The article also featured more information about a deep learning algorithm he and his team developed. See below for a an article preview […]
Identifying New Biomarkers to Detect Lung Cancer Earlier
Source: NIH National Cancer Institute, Division of Cancer Prevention Lung cancer, the leading cause of cancer deaths worldwide killing 1.8 million people each year, is often diagnosed at an advanced stage when the chances for a cure are limited. In the United States, almost 60% of people diagnosed with localized lung and bronchus cancer are […]
Thesis Defenses – Zhe Wang and Ke Xu
Congratulations to CBM PhD candidates Zhe Wang and Ke Xu, who both passed their thesis defenses on Thursday, April 8. Zhe Wang, of the Campbell lab, defended his thesis entitled“Enhancing Preprocessing and Clustering of Single-Cell RNA Sequencing Data” and Ke Xu, of the Spira/Lenburg lab, defended his thesis entitled “Airway Gene Expression Alterations in Association […]
Boston University researchers to develop new breast tumor models
Source: Eurekalert Breast cancer is the second most common cancer diagnosed in women in the United States after skin cancer, and women with comorbidities (the presence of more than one condition/disease) often fare worse in terms of their breast cancer. Researchers believe that comorbid conditions such as diabetes, obesity and metabolic disease may alter the […]
Past Event – Dr. Vijaya Kolachalama at BU AHA-GV Lecture
On January 25, 2021 from 2:00-3:00PM, CBM’s Vijaya Kolachalama presented “Unsupervised Machine Learning” at the Bu AHA-GV Lecture. Click here for additional lecture materials.
Dr. Joshua Campbell Receives Award from Lung Cancer Research Foundation
Joshua Campbell, PhD, Assistant Professor has received an award from the Lung Cancer Research Foundation. The award will provide support for two years to research “Determining differences in immunotherapy outcomes and immunobiology in African American patients with NSCLC”.
New Publication – Contextualized Protein-Protein Interactions
Source: Patterns Highlights We present PPI Context: contextualization of existing literature-curated PPIs A resource for filtering PPIs by cell-line information mined from reporting studies A fast and flexible pipeline implementing the presented data mining method The Bigger Picture Existing literature-curated protein-protein interaction (PPI) databases usually aggregate cell-type-agnostic interactions, yet PPIs are dependent on environmental conditions. […]